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Updated August 31, 2011


A persistent, often painful erection. The condition occurs when blood is unable to adequately drain from the penis. It is not associated with sexual stimulation, but may be caused by sickle cell anemia, trauma to the spinal cord or genital area, black widow spider bites, carbon monoxide poisoning, illicit drug use or certain prescription drugs. An antidepressant called trazodone is one drug which can potentially cause priapism. If not treated immediately, it can cause permanent scarring and erectile dysfunction.


"Priapism." The Cleveland Clinic Information Center. The Cleveland Clinic Department of Patient Education and Health Information . Accessed: October 12, 2007.

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