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Zoloft Dosage and Administration

Zoloft (Sertraline)


Updated May 09, 2013

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What Is Zoloft? | Dosage and Administration | Side Effects | Interactions | Warnings and Precautions | Should I Take Zoloft? | Stopping Zoloft

Zoloft, a selective serotonin reuptake inhibitor (SSRI) that is used in the treatment of major depressive disorder, is available in 25, 50, and 100 mg scored tablets, as well as a 20 mg/mL oral concentrate.

If you've been prescribed Zoloft, your daily dose should be taken at the same time each day. It may be taken with or without food.

If you are using the oral concentrate, mix an appropriate amount with water, ginger ale, lemon-lime soda, lemonade or orange juice only. Drink all of the liquid immediately.

Your particular dose will depend on your personal case and your doctor's judgment. Always follow the dosing instructions provided to you.


Medication Guide. Pfizer, Inc. Accessed: Jan. 27, 2010. http://www.zoloft.com

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