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Nancy Schimelpfening

Quick Tip: Wellbutrin and Alcohol Don't Mix

By August 31, 2004

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A member of our forum shared the following tip regarding the effects of alcohol while using† the antidepressant Wellbutrin:† "I took Wellbutrin SR for several months. I only drink occasionally, but the day after I had a couple of drinks, I would become more depressed. It would take around 3 days to snap out of it. I believe the alcohol would negate the positive effects of the Wellbutrin.†† For me, a few hours of being happier while enjoying a drink or two wasn't worth the days of depression that followed.† I don't drink at all anymore."--daisys4me

What have been your experiences with Wellbutrin and alcohol?† Did it make your depression worse?† Please share your thoughts below in the comments section.

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August 27, 2006 at 3:38 am
(1) kenneth says:

Don’t ever drink on Wellbutrin. I mean maybe a drink or two is fine. But be careful.

I’ve never taken any antidepressants, and my doctor didn’t bother to tell me no to drink. I had a good deal of booze and had a rather violent episode that i don’t remember anything of. Psychotic. Strange. Detructive.

I went apeshit haywire and could have hurt myself or someone else seriously if I didn’t have friends to restrain me.

December 4, 2006 at 2:06 am
(2) Mike says:

I drink, but when I started taking wellbutrin, I had to taper into it. At first, I felt really bad after just a drink or two. Now, I am almost back to being able to drink like I did before, although of course, it is always helpful in depression to stay away from the nectar. It definitely does put you in a slump after a big night of drinking however.

December 18, 2006 at 11:31 am
(3) Liz says:

I didn’t realize that Wellbutrin and Alcohol could be such an ugly concotion. I went to a party on Saturday, and after only a few drinks,I was so out of it, that I don’t remember the entire evening. People said that I was acting crazy. I’ll stay away from the drinks from now on.

January 23, 2007 at 7:07 pm
(4) Kate says:

BEWARE of the lethal combo! I started taking Wellbutrin a little over a year ago. My boyfriend and I tend to party. I have had some terrible, destructive, falling down, out of control, seriously wacked out behavior after having a few cocktails or wine. Although I think it has destroyed our relationship, I am thankful he was always with me – who knows what could have happened. Alcohol and Wellbutrin don’t mix.

May 14, 2007 at 2:07 am
(5) Chris says:

I’m so glad to find this — the exact same thing is happening with me and I had no idea what was up. I’ve found that a small amount of alcohol is fine, up to 2 beers or 2 glasses of wine (I weigh 175 lbs.) Anything more than that, enough to make you feel a bit dizzy, can make you feel sick for days. Depressed, exhausted, clouded thoughts…fortunately it has gone away after a week every time. I am a college student and used to be an occaisional big drinker before I took Wellbutrin, but now reading this, I think it’s going to have to stop! You’re right Nancy, days of depression is not worth a few hours of “fitting in.”

September 24, 2007 at 12:14 pm
(6) Joe says:

It is a seriously bad combination. I had two pints of beer one one glass of wine, which normally wouldn’t have bothered me. I began having random muscle twitches along with coordination problems; and apparently talking complete nonsense. I’ve found out that the alcohol Wellbutrin combination can cause seizures, which I avoided but it was a little to close for comfort. I woke the next day with a vicious hangover and went into a deep gloom for a few days. That was on only three drinks. While taking Wellbutrin one drink will give me a bit of a hangover and that’s about it. Still, it’s not worth it, so I’m staying away from alcohol as long as I’m on the stuff.

October 17, 2007 at 3:37 am
(7) Tom says:

Thank you all for sharing. Like Joe, I had three drinks (2 wine, 1 beer) to fit in and boy did I pay for it. I had just started Wellbutrin earlier in the week and was too embarrassed to tell people at a dinner party. So I accepted wine when it was offered to me and went along to a bar afterwards. I felt like hell the rest of the night and for days after–depressed, out of it, like I canceled out all the good and I was feeling when I earlier in the week and actually felt worse than before I started the drug! I still don’t feel back to normal yet, whatever that is on Wellbutrin. However, the first few days on the drugs were great. After drinking, the mild side effects I was experiencing were magnified by 100–terrible headaches, blurred vision, muffled hearing, and a sore throat.

January 25, 2008 at 2:33 pm
(8) Kelli says:

I have experienced blackouts while taking Wellbutrin and alcohol. And I just had two drinks the other night and felt bad for two days. Has anyone experienced blurry vision? Does it subside? Thanks

August 17, 2011 at 4:49 am
(9) Chase says:

Blurred vision is a possible side effect of Wellbutrin. Also it is said that alcohol can increase the side effects of antidepressant medication. I am on Wellbutrin as well, but I don’t feel to much in the way of side effects.. Only after a drink or two do I start to notice some things. Such as dizziness, occasional blurred vision (not bad), anxiety; all common side effects of Wellbutrin. I know.. crazy right? Anxiety is a possible side effect of the antidepressant? Talk about irony. Anyway, if you are worried about your side effects I suggest you mention it to your doctor. Happy Trails!

February 3, 2008 at 11:00 pm
(10) MLRB says:

Just wanted to share my experience in case it helps someone. I’ve been on Wellbutrin for almost 2 years now, and it has REALLY helped me get my life back. I feel like a completely different person, in a good way. However I can no longer drink socially. A beer or two, or a glass of wine, is usually okay, but honestly I try even to avoid that much b/c I may get raging headaches. The strangest episode occurred last night, when I went out with the girls and tried some new beers. I used to be one of those people who needed 6 beers before feeling anywhere close to drunk, but after 4 beers last night I was totally wasted. I barely remember the last few hours of the evening! And when I woke up this morning, I still felt drunk. Coffee did not help. Even now, at 10pm, I still have: Clouded thoughts, dizziness, confusion, weakness, tiredness, anxiety, and bad coordination. Doing my homework is totally out of the question. I must add that I recently went from a dose of 100mg to 300mg, and this is the first drinking I’ve done since the increase. DEFINITELY practice moderation if you are on a higher dose. I don’t want anyone else to feel this way! I do want to add, in case anyone else is wondering, that I have not had any negative reactions with mild marijuana use (but all things in moderation!). I would much rather relax that way than drink, so I think the beer-tasting parties have come to an end! I’d like to keep the 3.5 GPA I’m maintaining, so it’s no big loss anyway. Hope this helps!

August 9, 2011 at 3:02 pm
(11) Aaron says:

Caution: craft beers sometimes drink like wine @ 12+%alc by vol. been there.

February 9, 2008 at 8:20 pm
(12) AllenT says:

This is confusing. I just started taking wellbutrin and I havent experienced any side effects from the combination of alcohol/wellbutrin. I drank about 5 ounces of vodka last night and didnt feel any different than usual.

February 18, 2008 at 7:10 am
(13) Drikk says:

A very interesting thread, as everywhere else the discussion of wellbutrin interaction with alcohol is limited to seizure risk. Yet I experienced sth quite similar to this.

I’m on 150 mg of wellbutrin sr, went for drinks with friends and after 3 drinks got quite out of control, feeling so full of energy and very agitated. Feeling unstoppable. After another 5 drinks friends went home, so I also had to. For the next 3 days I was totally spaced out, unwilling to communicate to anyone, uninterested in anything. A typical side effect?

March 11, 2008 at 7:56 pm
(14) Dayna says:

Thanks for all your comments they have really been helpful. I have been taking wellbutrin(generic) for around 6 weeks or so and am noticing many positive side effects. I have taken many other AD’s and noticed that when i would start a new AD i would feel a euphoric high for the first couple times taking it. When i was younger and “trying to catch a buzz” i would mix wellbutrin with other substances that i had turned to before such as alchol, marijuana and other perscription uppers or narcotics. I felt unstoppable as many have you have mentioned. I notice that taking the medicine exponetionally increases my buzz in quite a dangerous way. I have actually given away my pills to a friend in order to see how he responded, and he felt “amazing” after one pill and only two beers. Not to recommend mixing the two because it has worked out badly in some circumstances, just wanted to make new timers aware that it will make you feel good. About a week ago i went out with some friends from work and had prolly two shots and a few beers, and was surprised at how tonked i was. The next day for the first time after mixing the two i felt terrible (like most of you reported here). Im not sure why now it effects me now more than before. I suppose that my frequent substance abuse in the past allowed me a tolerance whereas now i am again a “lightweight”. I guess my point is to agree with above comments while also stating that you should be careful not to become your own worst enemy because the combo can be quite entertaining…….

March 27, 2008 at 1:50 am
(15) Pam says:

Ok, this is really weird. I feel like the lone ranger here because I can’t feel the effects of alcohol since my dose was increased from 150 to 300. I can drink one beer after another and feel nothing. Or my favorite drink – margaritas – I used to get buzzed after one drink but now I feel nothing after I drink three of them. It sounds like I am having a completely different experience than everyone else.
Also, I experienced blurred vision in one eye a few days ago. No alcohol in my system – my right eye just started to see double. It scared the crap out of me when it happened because I thought I was experiencing a stroke.

June 25, 2011 at 11:14 pm
(16) Heather says:

I have a similar experience Pam. I never drink and so one would think that when I have a night out drinking with old friends until 3 AM, that I would be smashed! No, my thoughts, speech, motor skills, were fine. After many shots and drinks it was as if I had had just a few. Even the next day, no headaches or stomach issues. I was tired, but hey I’m 41 and am normally in bed by 11. Strange!

July 2, 2011 at 8:04 pm
(17) tara says:

me too Pam,,,on 150mg Wellbutrin, and it seems like i cant get buzzed anymore without drinking ALOT of beer….always up at early hour too!!!!!!!!!!

July 15, 2011 at 3:46 pm
(18) Lisa says:

“Ok, this is really weird. I feel like the lone ranger here because I canít feel the effects of alcohol since my dose was increased from 150 to 300. I can drink one beer after another and feel nothing. Or my favorite drink Ė margaritas Ė I used to get buzzed after one drink but now I feel nothing after I drink three of them. It sounds like I am having a completely different experience than everyone else.”
–I am just like Pam; I have had the complete opposite effect of most of the posts here. Before Wellbutrin, when I would go out and have a drink, I would get drunk after 1-2 drinks. I’ve always been a total lightweight.

I notice when I have had drinks since I started Wellbutrin almost 2 years ago, that I actually CAN’T feel my alcohol. It is very, very weird, because, as I said, my whole life, if I had a drink, I would be buzzed or drunk after 1-2 drinks; now I feel nothing after having several. I don’t get it… I wish someone could tell me why this is. It is very weird….

I am on 100mg once a day of Wellbutrin; and 75 mg of Zoloft once a day.

November 29, 2011 at 3:03 am
(19) Evan says:

I’m on 450mg a day for the past 2 years and started taking it before ever trying alcohol. Since I’ve started drinking 6 months or so ago, and I have never felt an alcohol induced symptom, no “buzz”.

Still, with the knowledge that Wellbutrin and alcohol don’t mix well, I’ve never had more than three strong drinks. So, take my story with a grain of salt. I also don’t recall feeling any ill effects the next morning.

March 31, 2008 at 12:11 pm
(20) Sheila says:

I have been on wellbutrin for about 2 months now and really feel fine drinking on it. I don’t have weird “drunk spells”, or any side effects. HOWEVER…the next day I am very depressed and feel down all day long. At first I couldn’t figure it out but realized the days of feeling really low were always followed by a day or days of drinking. I usually did not get drunk either, but one week, I drank wed, thurs, fri, and sat, and by the time Sunday came.. it was terrible and not worth it!!! Look at it this way.. when you drink the meds dont’ work.. So not only did my meds not work from wed- sat but i added alcohol which doubled the negative effect. It all makes sense.. Choose your poison.. right now wellbutrin is where I’ll stay!!!

April 9, 2008 at 1:50 am
(21) Jessica says:

Today i was moved to three hundred milligram wellbutrin xl from one fifty. Forgetting i had already taken my one fifty dose i proceeded to take a three hundred, therefore taking the maximum dose of four fifty. i`ve, of couse, after taking such a high dose not felt like eating all day. i recently had three to four large shots of ninety nine proof alcohol and a good bit of marijuana and feel very tired but at the same time very good. it does feel like a different kind of drunk but not necessarily a bad one.

April 27, 2008 at 10:43 pm
(22) Paul says:

Been on 450 mg for about a year, up from 300. Wellbutrin has kept my binge drinking under control but I still like to have a few now and then. Not a good combo. Before XL I was having 20-25 drinks a week. Now I find i can handle 1-2 drinks occasionally but if I do it consistently (e.g. more than twice in a week) it catches up to me and I spend a week to 10 days in depression. On the rare occasions now that I have over 4 drinks I feel depressed, uncommunicative, irritable for about a week. Not worth it for me so I try to abstain.

May 1, 2008 at 5:45 pm
(23) susan says:

Omigosh! I’m so glad I found this forum. I’ve been mystified by the dramatic increase in my sensitivity to alcohol. I began Wellbutrin a year ago, and my tolerance has gradually gotten less and less. I now get VERY drunk VERY easily, and for the first time in my 52 years I’ve had drunkenness-related lapses in memory, lapses in judgment, double vision, passing out, 2-day killer-hangovers, severe guilt, and the like. Wellbutrin is great, but it’s made me a lightweight! Two’s my limit from now on. Thanks for sharing your experiences, everyone!

May 21, 2008 at 9:33 pm
(24) Michael says:

I’ve been on wellbutrin 150mg xl for 3 weeks and for the first two weeks I avoided drinking at all but drinking is a large part of my social life (I’m in college and have a little bit of social anxiety). So when I drink I really drink (at least 5 drinks) and the only thing is the second time I drank I had a pretty bad hangover that lasted well past the morning. I normally don’t get hangovers at all.

June 26, 2008 at 1:09 am
(25) Trevor says:

I’ve been on Wellbutrin XL for 9 months now and it’s definitely affected my drinking experiences. I’m on 300 ml a day. When i first started taking Wellbutrin, i could barely drink at all without getting drunk way to easily. It hardly takes anything to get me drunk anymore and it used to take a lot. I’d be careful while on this. I am vomiting a lot now after I drink and I never used to before. My advice is to definitely pace yourself if you are planning on drinking. That seems to negate the negative side effects.

August 9, 2011 at 2:59 pm
(26) Aaron says:

I long for the days of vomiting. It’s natures red light. I’m just putting two and two together…. I’ve always liked to drink but did not black out like this….I’m losing friends right and left ( FB tells me so, although the individuals concerned say nothing to me any more) I don’t know which to give up, my social life revolves around drinking. I’m on 300mg/day and I’ve thought it is doing me a service. Now I’m not sure.

June 28, 2008 at 9:29 am
(27) Laura says:

WOW! You’ve all just described my experience since taking Wellbutrin! For the past 3 weekends I have become drunk(either passing out or unbelievably energetic)on WAY less alcohol. I’m now a “cheap date” when it used to take large quantities of vodka for me to feel any effects. I also have wondered why I’ve been feeling so down again lately. Thank you all for sharing! I know now what is going on and will def be more careful.

June 29, 2008 at 1:36 am
(28) Marie says:

Thank you all so much. I thought I was crazy because the only stuff I could find on wellbutrin + alcohol was all seizure-related. However I feel like I get wayyyyyyy too drunk wayyyyyyy too easily and I blackout for hours at a time and do things I would never do before no matter how drunk I was. I don’t know what to do because I am a college student and drinking is a part of my lifestyle. Unlike some of you though, Wellbutrin does not increase my hangovers or depression. Just the extreme sensitivity to alcohol. Can anyone suggest a similar AD that doesn’t have these effects? I’ve ruined so much in my life these past few months because of being too drunk and out of control on just a couple drinks. Please… help.

May 22, 2011 at 2:28 am
(29) Peter says:

did you find a similar AD that doesnt have the effects?

August 12, 2011 at 11:38 pm
(30) Amy says:

Are there any other AD that you can drink on and not have this huge problem?

June 30, 2008 at 2:34 pm
(31) Kim says:

I am so glad I found this forum! I thought there was something wrong with me. I was out the other day at a festival and was very cautious about pacing myself while drinking beer…..but when I hit the hard stuff (sambucca)well thats all she wrote. i dont remember ANYTHING after about 15 minutes from drinking that stuff. I had amnesia and I think this is because of the mixture of Wellbutrin and the “hard” stuff. I was fine as long as I was sipping on beer. Well at least I now know I am not crazy or the only one who has experienced this.

July 3, 2008 at 2:02 pm
(32) Hannathema says:

Like everyone else, I am so happy to have found this discussion! I am frustrated by pharmacists and doctors that when asked a question (i.e. this question) respond with the cliche pharmaceutical warnings. I started taking 300 mg of Wellbutrin (for ADHD/ depression) over a month ago, and am ashamed to say that I have no idea what the drug “does” to my emotional state, because I have been on a drinking binge ever since the semester got over (in large the fault of Adderall, which caused huge depression.) I suspected that I was f*cking things up with the drinking (@ 50 drinks per wk, Female, 22 yrs. old, 130 lbs), but am used to feeling like shit. I can drink more than ever (maybe just tolerance rising), I never get sick, but get wasted…the end of everynight is either blurry or blank. I am also hugely emotional…I have lost friends, and I carelessly lost my heart, and am full of regrets. I pull myself together in the morning, punish myself in the gym, fight the fog and constant stomach and head aches, and then night rolls around…

I’m rambling.

Thank you for sharing your experiences…more evidence for me that this med might actually help…I just need to put down the bottle.

November 29, 2011 at 12:06 pm
(33) Wonda says:

If you can stop drinking, I guarantee you will feel better! Alcohol is a depressant! It does mix well with any antidepressant!!! You will feel so much better with out it. It will also destroy your liver..hugs!!!!

July 3, 2008 at 5:39 pm
(34) Bobby says:

I’ve been taking Welbutrin for about 2 years now and when my dr increased the dosage from 150mg to 300mg all hell broke loose. After having a few drinks I would wake up and wonder how I got home. People would tell me I did things that I do not recall at all. It’s like having amnesia. I’m so glad I had friends around who took care of me !! I could have easily been mugged in that condition.
Also, it would take me 3-4 days to recover!! Just crazy !! Be very careful, never mix Wellbutrin and Alcohol.

July 4, 2008 at 3:17 am
(35) Rusty says:

I am currently taking Wellbutrin (Bupropion) @ 300mg a day and have quite mixed feelings about it. At first it made me lose my appetite and I could hardly sleep at night. I was very happy throughout the day and had abnormal energy levels. Previously 6 months leading up to this med I tried Lexapro for 1 month and Effexor for 6 months. The Lexapro did nothing and actually made the alcohol effects increase. Effexor made me numb to almost any level of alcohol or marijuana, scary since I was already very tolerant of both. It also made me apathetic about everything. It seems that every time I went back to my regular doctor he would prescribe whatever is the latest and greatest. Genetically I am subject to high normal blood pressure which is evident when I go to the doc yet he prescribes me meds that go against this condition. Effexor was hell to get off of, total disorientation and withdrawal. If it werenít for my high consumption of marijuana at the time I donít think I could have done it. There have been several bouts of exercise, healthy lifestyle, and total discontinuation of M & A but it seems that I get extreme anxiety that gets triggered by my emotionally challenged life and back I go. Lately I keep stopping the Bupropion for a day or two and always go back for fear of what could happen. I am not sure about these meds at all and their effect on certain types of people. I have a tendency to overanalyze the logical aspects of any type of substance in my body and I am coming to a point where I donít think I can have anything like this in my system. Marijuana does almost nothing to me no matter the potency, how often or how much I use. I understand its effects and can rationalize them when it is in my system. Ignorance is bliss…. Alcohol is the same way. I can go thought 48 beers in a weekend and never blackout once nor forget any part of it. It seems that they dull a certain part of my brain that is not functioning properly. I have come to a point where I am seeking an actual doctor in the field of psychology not some BS counselor that always tells me to journal my feelings and use breathing techniques yet offers no feedback after I dump all of my cherished thoughts and past experiences on them. Believe me I have a lot of unfinished business and I am in no way a typical case but I feel that these drugs are not right for some of us with certain brain chemistry. I still do great at my job and solve difficult logical problems with ease all day long but everything else is a blur to me. I have always been able to self medicate and still take care of my life but since I chose to start anti-depressants my life has been out of control. My brain is not functioning normal. Maybe related, maybe not, just an obvious change.

July 6, 2008 at 12:28 am
(36) barb says:

I took Welbutrin a few years ago when I was 23 and my friends kept saying that I would get drunk really fast and act kinda revved up. I didn’t really see it so I didn’t take their warnings until I blacked out, got completely naked and peed in the corner of my new boyfriends room! I have never peed during drinking and I didn’t have enough to black out. It was scary and I was takin’ off it. I definately think that my tolerance is lowered and with too much alcohol blacking out happens alot when on antidepressants. Alcohol and antidepressants are trying to combat each other in your brain. Its not good.

July 9, 2008 at 12:54 am
(37) Roman says:

hey im taking wellbutrin as well , so im cool if i just take 2 beers ?? , and another thing does anyone know if there is any issue with smoking cigarretes and taking wellbutrin , i apreciate any information about that thank you

July 12, 2008 at 11:32 am
(38) Kris says:

Wellbutrin (Zyban) is actually used to help ppl to stop smoking. It doesn’t hurt you to smoke while on the med, but it can help you cut your addiction to nicotine quite nicely if you use it properly.

July 20, 2008 at 12:32 pm
(39) Maggie says:

I started taking welbutrin more than 10yrs ago for cyclothymia (rapid-cycling manic depression), obsessive-compulsive syndrome and suicidal tendencies… there has been some question that I may also have borderline personality disorder… I think it’s all ptsd from childhood abuse… I’m also in menopause. Point is, last spring we started playing with the dosage because I was under incredible stress( I had been taking 75ml 3xday, but switched to 100SR) and I started having these violent rage attacks. I was let go from my teaching job, and then started drinking and smoking weed like crazy. It got worse: one night I flipped at a bar and began crashing a barstool on the ground. Blackouts happened regularly, I stopped eating, just got really out there. I was also having off the wall hive attacks to foods I’d never had problems with. I switched to 150sr recently and feel a lot better. The rages stopped, nightmares and sleeplessness decreased, overall enjoyment increased. It seems like the dosage and form have a huge effect on my emotional and physical stability. Talk w/ your Dr honestly about your lifestyle and tendencies: I almost landed in jail. As my mother would have said, “(That’ll) give you something to cry about!”

July 21, 2008 at 2:10 am
(40) Marly says:

Been on Wellbutrin for a little over two weeks. Friday night I took two shots of rum and caught a buzz very quickly (not normal). Then I decided to go get more (big mistake, I wish I could take it back). Talking to a friend on the phone I snapped and went off on him over absolutely nothing, I was screaming at him about something completely unrelated to the conversation. Arriving back home, apparently I drank roughly another 3 shots based on what was gone out of the bottle. Again this should not have been a problem, although it wasn’t normal for me to be drinking by myself (I missed that clue). Usually I’m the giggly drunk who loves everybody. Now, for the really bad part that I don’t remember. Apparently I spent two hours (intermittently, I kept hanging up) on the phone with a friend, while he was at work. Crying, hysterical, talking non sense and threatening to kill myself. He was so freaked out he got a hold of my mom to have her come check on me, this was just so completely out of character for me. She found me, passed out on the floor with a plastic bag duck taped around my head. I could have died and I don’t even remember any of this! I had to hear about it the next day! The irony here is that I am not taking wellbutrin for depression, I’m taking it to quit smoking. My friends have reached a consensus, the pills are making you crazy please keep smoking (I did quit). The alcohol warning lable needs to be more specific “Lowers tolerance and may make you paranoid, suicidal, irrational, delusional and anything you can think of that is the opposite of who you are normally.” All of that off of 5 shots of rum, hehe normally that’s just a good night.

July 24, 2008 at 5:35 pm
(41) Jesse says:

DO NOT DRINK WHILE ON THIS MEDICATION! I am so glad I found this forum since I am trying to make sense of last night. I just started taking Wellbutrin 2 days ago to quite smoking. I consider myself a regular drinker but a happy drunk. Last night, I blacked out, hit my boyfriend, ripped his shorts off and scratched his face up. I woke up this morning without a trace of any memory. This is not typical behavior for me and I am shocked I got so out of control. This was scary and it is not worth it to have a drink. Read the label on your bottle, WHEN TAKING THIS MEDICATION DO NOT DRINK ALCOHOLIC BEVERAGES. Be careful even if you have a record of holding your drinks, you may wake up in a strange place with blood on your hands or even worse a bag on your head like Marly. My doctor said I could drink in moderation while taking this, that is BS because no one should drink while on this, not even just a little.

July 28, 2008 at 12:28 pm
(42) Sinceri says:

I’m glad to have read all your blogs. I have been on Wellbutrin for a couple of years. I love it! I cannot drink with it. I’ve had episodes thinking I’m the Incredible Hulk, and that’s not good. I have to stop drinking, its hard since its such a part of my social life. I can’t deal with the guilt or the depression afterwards. Thanks so much.

July 31, 2008 at 4:29 pm
(43) Erin says:

I have been taking Wellbutrin for about 10 years. I started when I was 17, after my mom died. Since then, I have been a regular drinker, drinking massive quantities, while taking my medicine. I have had tons of psychotic episodes when drunk, looking back, but for some reason attributed it to the alcohol and didnt even consider the Wellbutrin was causing them. I recently reduced my dosage from 300 to 150 and I feel more clear headed. and I have been drinking less because Im back in school again at the age of 29. It’s crazy to think that all of the ‘issues’ I have had all these years, and unnecessary fights with boyfriends and crazy behavior might have all been caused by the medication that was supposed to be helping me. although, I guess I always knew. Im going to try to ween off of it or quit drinking.

August 1, 2008 at 6:45 pm
(44) Sessie says:

First off, anyone who is taking Wellbutrin is obviously suffering from depression so regardless if you are taking Wellbutrin or not, the day after drinking will not be fun. While taking Wellbutrin, the effects of alcohol will be increased and your seizure threshold will be lowered due to the Wellbutrin but if you are not prone to having seizures already, you most likely will not have one. Some people may be fine drinking on Wellbutrin anf some not, but remember your bodies natural responses to alcohol will most likely be increased while taking Wellbutrin. Depressed people will feel depressed after drinking.

August 4, 2008 at 2:02 am
(45) Patrick says:

I’m on 300mg Wellbutrin daily and I take Klonopin regularly, both for Social Anxiety (Wellbutrin was originally for quitting smoking). I also drink regularly, including when i take the Klonopin, and I noticed no side-effects at all. Maybe the only difference I see is that I get drunk quicker, probally because of the Klonopin. No hangover. No nothing.

August 9, 2008 at 7:54 am
(46) Marley says:

SESSIE: Obviously not suffering from depression. Wellbutrin was prescribed for me to use as a stop smoking aide. After looking into wellbutrin a bit further I learned it LOWERS your alcohol tolerance significantly while also increasing the rate at which your body absorbs the drug. I BLACKED OUT from 5 shots of the candy rum (not even full strength 80 proof).

April 19, 2011 at 1:12 am
(47) Ainge says:

All smokers are depressed. Snap out of the delusion.

April 27, 2011 at 10:32 pm
(48) Jeff Hamielec says:

Nice Ainge LOL I’d be offended if I was sure that you were wrong….

August 10, 2008 at 1:15 pm
(49) Noey says:

I have only been on Wellbutrin Xl for 36 hours and in that time I have had about 3 drinks. I highly DO NOT reccomend drinking on this. Last night I had to cut my night short and laid in the fetal position having chills and muscle aches for hours. I have been an experienced drinker for a while and realized it was getting me no where. I made the decision to finally get on this medication and that outweighs drinking I am afraid.

August 17, 2008 at 1:31 am
(50) Robert says:

I have been on Wellbutrin for about 6 months now. I take 150 SR twice a day. I have also been drinking for a very long time. I did not discontinue my alcoholic behavior since i started. My tolerance to alcohol did not change at all. I continue to drink every night and I have not felt any difference in my tolerance. Drinking has been a serious problem for me as far back as I can remember. I have always been known to overdue it. Drank 20 beers last night and also upped my dose to 450mg for the evening. I do notice that I have serious mood swings at times and it could be because of this. Last night I cried out of control. This is why I uped my dose. I also use marijuana and have been known to use xanex, morphine, percocets, and vicodins while on this drug. I did notice the wellbutrin was helping within the first days i used it. I also have tried to stop drinking recently and on the second day I felt real wierd. Tripping out with high anxiety. Peeking out my window and getting sweats. Dont know if its from stopping alcohol or from mixing all this stuff. I wanna quit but feel as though I cant without proper counseling and meds. It is crazy to read these posts and see how everyone else seems to get more wasted than usual. I abuse alcohol and prescription drugs and feel like usual. High but like usual. I must have a serious problem. I just want to be normal and happy with my life. My mood swings are very strange. I usually am no longer depressed but it hits me every so often. I need to see my doc and hope something can be done. I have no side effects on this med and think it helps. Dont know if i need more meds or what. It feels to not make me as happy as it did in the first 2 months. I am ****** up and dont know what I can do. If anyone has any advise or suggestions I would appreciate your reply. Well gonna go finish some beers and smoke a bowl. Boy I hate to feel this way. I guess I am lucky to not have had a blackout or experienced a siezure as of yet. Wonder if my day is coming. I am usually motivated and keep a 3.8 GPA in college. I know I have a problem. I just dont know what to do about it. Does anyone have any ideas. Thanks for your posts. Once again as usual I feel like an outcast.

March 6, 2011 at 10:29 am
(51) Jen says:

Robert I was really touched by your post and although it’s from 2 1/2 years ago, I am curious to see how you’re doing, if you’re still around.


August 17, 2008 at 10:51 pm
(52) me says:

Been on 150 for a about 6 weeks or so. Was on it a year go. Worked okay, went off, now it doesn’t work as well.

I have been drinking quite moderately. 2 light beers last night. Glass of wine tonight and 1 light beer earlier. I feel like hell. I want to die. I think even this small amount of booze is making me feel worse and worse. Today I had a public flip out. Was perfectly fine one moment – what should have been a minor aggravation flipped me out.

I don’t know the solution. Will stop drinking period, but I think the Wellbutrin is messing me up even when I’m not drinking.

Please everybody get off this drug. I will pray for us all.

August 25, 2008 at 11:02 am
(53) Valerie says:

Yeah, I had an extremely psychotic episode while drinking just this past Saturday night. I may have ruined my boyfriend’s life forever and I attacked (verbally) an innocent girl for no apparent reason. I am usually not mean and aggressive and abusive like that at all. I broke a glass. I was out of control. As long as I’m wellbutrin, I’m never drinking again. I don’t know if my boyfriend will ever be able to forgive me/restore his friendships and remain in his running club, which is his entire existance. :(

August 31, 2008 at 9:36 am
(54) K says:

I have been taking Wellbutrin for about a month and thought the antidepressant effects were just inconsistent. One day I would feel fine and the next depressed. After reading all your posts I realized the inconsistency is due to alcohol intake. I didnít put it together until now. Iíve had a lot of social events this summer and Iíve had a few drinks at each. The next day the Wellbutrin didnít ďwork.Ē I havenít experienced any of the out of control behavior that some have talked about (thank God) just a little down on the day following a wedding or party. Itís not worth it to me. Iíll drink club soda with cranberry from now on. I’m really glad I came across these posts.

September 3, 2008 at 11:19 pm
(55) Robert says:

Well my doctor told me when first prescribing the medication that the alcohol does not work with Welbutrin. She said that the pot smoking is not that bad even though it is considered a depressant but she said the alcohol must stop in order for the drug to work. I think I should give it a try. What do I have to lose anyway?..A buddy told me something at school today…I told him of my drinking and lack or self motivation or care and he said….If you dont look out for yourself who the hell is going to look out for you?…..I knew alcohol was my problem but never cared to correct it…He said I should treat myself like a king just like he treats himself….This made so much sense to me…if I dont care about myself it does not matter how much help or support I have or anybody has…I hope to stop my corrupt lifestyle very soon. Thanks for all the posts.

September 10, 2008 at 9:03 am
(56) Mr.B says:

It makes sense to me now! I’ve been on wellbutrin for about a week. The first two days were great, I started feeling in control. The third day I had about six or eight beers and a couple glasses of vodka cran. The next day I forgot to take my pill in the morning. I didn’t have a hang over, but I felt like shit, depressed and very easily agitated(I have two young boys so it don’t take much some times!).I thought maybe it was that I let the meds ware off but after two days I still felt like shit. It’s been three days and I’m finally feeling good again. I love to drink socially. I don’t think it will happen anymore. NOT WORTH IT!!! Thanx everyone and good luck!

September 24, 2008 at 12:57 am
(57) chole says:

Never ever ever drink more than 1 or 2 drinks while taking wellbutrin as i did and basically don’t remember the whole night. I didn’t drink that much to blackout like i did. Friends said i did some things that were absolutely bizarre and completely out of character for me. I will never drink more than 2 drinks while taking this very powerful drug.

October 3, 2008 at 12:51 pm
(58) Lilstuff says:

I am currently on Wellbutrin 300XL daily.. I’m a 29 year old female and drink nightly at least 3-5 beers.. On weekends, a little more. I have not noticed anything different except that maybe I get a little more of a buzz faster.. And sometimes, after just a few, i just won’t even feel like drinking anymore. Since taking the XL, there’s been a HUGE improvement in my mood and drinking alcohol doesn’t seem to affect the effects of the Wellbutrin in any way. I still feel great! Now, i haven’t gone out and gotten blitzed since being on this medication.. I don’t go NEAR hard liquor.. My experience is only while at home.. But, i just thought I would share because I was very concerned myself when I was first put on this medication. I hope this helps anybody who’s wondering the same thing…


October 4, 2008 at 6:12 pm
(59) francine says:

MARLY – you must have been terrified hearing that story, I certainly was and it’s made me decide NOT to take any chances with alcohol and wellbutrin. On a MUCH less severe scale, I woke up this morning after four glasses of wine over dinner at my brother’s house to find vomit everywhere (sorry, it’s gross). All over my bed, all over my beautiful new white rug, and I don’t remember it at all. I’ve spent the entire day getting sick with more intensity than ever before, and I feel lower than low. I appreciate the information from this post, mostly for the ways it can help me change some stuff to try and get better. I’ve lost most of my friends, not because of outbursts, but apparently, from my increasingly gloomy/boring/irritable attitude over the last couple of months. I can’t think of what they mean, and I’m generally overly self-analytical. Nothing like the blacked-out sickness had happened before, so to the people who have seen no effects – that’s what I would have said yesterday too. Take the opportunity to dodge having to learn the hard way that these things probably just don’t mix.

October 13, 2008 at 1:17 pm
(60) Gretchen says:

I have been taking 450 mg. Wellbutrin every morning for probably about a year, and drinking at times as well. Last week I had quite a lot to drink one night, took my Wellbutrin as usual the next morning, and suddenly had a full-on seizure in the afternoon. I knew nothing of it, but apparently I was thrashing uncontrollably all over the place and it took me quite some time to come out of it (my husband was present). Afterward, my tongue was swollen, abraded and painful along both sides where I had apparently bitten it repeatedly, and my arms and legs ached as though I’d had a serious workout. Absolutely do not mix this stuff. I cut out alcohol immediately and I feel so much better (much less depressed too), I wish I’d dropped alcohol years ago.

October 18, 2008 at 12:39 pm
(61) tyboulder says:

I just started wellbutrin 3 weeks ago. I was on 150mg and just recently upped it to 300mg. I’ve read a lot about many medications, but I’ve never heard about wellbutrin and alcohol mixing like this. I have a really stressful job right now, and I’m always anxietized, so I don’t know if wellbutrin is the right drug for me? When I’m less depressed it’s easier to get things done (ADD). But thank you so much for the early warning on alcohol everyone! I binge drink about once a week (avg. 10 drinks), so who knows what might have happened. I was insane(!) on 40mg of paxil and alcohol. Good luck all.

October 21, 2008 at 9:30 am
(62) olivier says:

Well! This, is a really useful issue: wellbutrin and alcohol… I’m on a combo wellbutrin/sipralexa (serotonin-like) since two weeks, on 150 mg, morning.
After 2 days, I felt like my energy was back again (I have been feeling extremely tired for several years, after a mononucleosis and the CMV (cyto megalo virus). Then, I had quite a few drinks with my wife in the evening and the NEXT day I really got the feeling that Wellbutrin was not “working” out anymore!
That, corresponds to what you say, all of you: wellbutrin seems to “block” its working in presence of alcohol.
I think there is a choice to do there, don’t you think so? ((; Wellbutrin… or alcohol.
I don’t see any other way. Olivier, Brussels, Belgium

October 30, 2008 at 3:37 pm
(63) Claire says:

I have been on Wellbutrin-XL 150mg daily for 10 days, and abstaining completely from alcohol for 11 days (stopped drinking the day before starting the drug). I am not feeling any better yet from the drug, but want to give it a fair trial of 2-4 weeks without alcohol. Previously I was drinking 2-3 drinks daily and more heavily 1-2 times per week. I will definitely limit my alcohol to 1 or 2, if any at all, the next time I am out with friends. Thanks to everyone for your stories. I hope that I won’t have one to tell when I eventually decide to have a drink or two.

November 2, 2008 at 11:22 am
(64) Jackie says:

Like most of you here, I thought i was the only one. I have felt such excessive rage today that I banged my head against a door, could not stop slamming doors, swearing and shouting at everyone and it scared the hell out of me. I have been taking wellbutrin now for 2 weeks and i have felt increasingly more anxious and agressive. I went out on friday night, (it is now sunday) only had 2 drinks (double spiced gold, then a cider) and I actually started to feel off so I went home. I have also been finding that if I do smoke a cigarette, i feel nauseous and want to throw up. I also midly smoke marijuana (few puffs of a joint every now and again, so I am also wondering if that would have any effect? I will wait it out, see if things improve but i dont like this, im ruining every relationship by freaking out and hitting things.

November 2, 2008 at 1:03 pm
(65) Peter says:

A lot of these comments mention blacking out and doing intensely odd things, but couldn’t it just be the Wellbutrin lowering your tolerance? I’ve blacked out once in my life and I wasn’t on any medication at the time and I acted extremely nuts clawing at my friends face violently.
I’ve only been on the stuff for just over a week but what’s been happening to me when I’ve had just one or two drinks (and mind you I have a very very high tolerance level) is that for a period of maybe ten seconds or I will be trying to say something and it just won’t come out right. It feels almost as if I’m on a psychotropic substance. It’s very strange but I kind of like it all the same!

November 3, 2008 at 2:43 pm
(66) Terrified says:

Booze and Wellbutrin… Never again would I make that mistake. I’m a career alchy, ALWAYS drinking ALL the time, morning, noon and night. Two years ago, I took Wellbutrin 300mg for about a week and then on the weekend I did my normal thing, drinking from the moment I got up ’till I passed out in the afternoon only to wake up and drink some more. Except that instead, I never passed out. I became anxious. Then more anxious. Then so anxious that I called a friend to come over because I felt terrified(of nothing). Eventually I was in a barely controllable state of panic that lasted for a day and a half. I spent the whole night on my couch crying and rocking, smacking my leg in an attempt to try and get control of myself. My friend wanted to take me to the hospital but I refused.

When I finally recovered I knew one thing for certain… I could either drink or take Wellbutrin but I couldn’t do both. I had to make a decision…

The pill bottle is still in my cabinet, mostly full and with two refills left.

October 17, 2011 at 2:00 pm
(67) ck says:

this is so funny

November 3, 2008 at 3:40 pm
(68) Amy says:

I have been on Wellbutrin for 5 months. When I drink, I get extremely flush, so much so that my skin gets red and blotchy. Also, I feel a tingling and numbness in my head. Does anyone else experience this? Also, wicked hangovers!

November 18, 2008 at 4:19 pm
(69) Question Mark says:

Unlike many of the preceding comments, Wellbutrin/Budeprion SR (150 mg) was prescribed to me for smoking cessation. I don’t have depression/suicidal/alcohol issues; I’m just trying to overcome my “desire” to smoke. When the doctor told me the Wellbutrin/Budeprion SR MIGHT cause seizures, I decided to never take them even though there is no history of seizures in my family. The 24-hour (prescribed) patch has been effective for reducing my physical desire to smoke, but I’m desperately “missing” that “kick” in the back of my throat after inhailing, and I miss the taste of smoke in my mouth. I was told the Wellbutrin/Budeprion would help to remove those desires, but I’m not willing to risk flopping on the ground like a fish out of water. Has anyone else used this drug for smoking cessation? Does it remove the desire to want to smoke without (alcohol assisted) nausea?

November 20, 2008 at 10:03 am
(70) Steve says:

I’ve heard mention of other AD’s here like Effexor. Stay away from that stuff. I’ve been on it for about 3 years. I wasn’t depressed, or even happy for that matter. I was just flat lined. What’s worse is when you miss one dose. The muscle aches, the “Brain Zaps” etc.

As far as Wellbutrin is concerned I believe its the best AD on the market, despite the side effects when you include alcohol.
I find that if I have 1 drink a week I still wake up in the morning with a headache, but if I have a few during the week it doesn’t seem so bad. I’m not sure why this is. Anyone else have the same symptoms?

November 21, 2008 at 9:57 pm
(71) Stacie says:

AMY-I have also experienced blotchy, hot skin while drinking. I haven’t had many other side effects and I’ve been drinking a lot lately (4-5 drinks a night at least twice a week from nothing at all).

I’ve been on 100 MG Wellbutrin for close to 2 years now. It has helped me so much, but I just recently started drinking and worrying about the effects. I haven’t noticed anything horrible like what I’ve read above, and I think it may be because I’m on such a low dose.

I’m worried about any possible long term side effects or anything REALLY dangerous. Does anyone know if mixing alcohol and Wellbutrin can harm you more than just giving you bad side effects and increasing risk of seizure? I’ve been trying to find this answer forever now so if someone could help, that would be great! Thanks!

November 22, 2008 at 1:51 pm
(72) robby says:

yup yup… like most everyone here, i ended up on this page after experiencing the worst backlash from drinking that i have ever had. I am on 4 doses of 75 mg IR 6 hours aparing for quitting smoking. A couple of days ago i went out w/ some friends and had maybe 3 beers and a shot. No black out or strange actions yet the next day i spiraled into the worst depression, paranoia ever. I turned off my cell phone and refused to communicate with anyone except my DOG for 2 days. WTF? My doctor never mentioned this and the Wellbutrin web site makes lite of the combo. I am 100% positive that my extreme reaction was due to Wellbutrin especially after reading all of the postings above.

November 26, 2008 at 11:41 am
(73) Lilstuff says:

Just like to comment again.. still taking 300 XL daily. Still drinking daily.. Wellbutrin still working strong! Nothing different when i drink. Maybe i’m one of those rare few.. I can’t believe how it can affect everybody so differently! :)

November 30, 2008 at 2:44 pm
(74) aracely says:

I’ve been on wellbutrin sr for almost three months I’m on 300 mg and I had been avoiding any type of alcohol consumption due to the risk of seizures. Yet, on Thanskgiving I decided I was going to try a new wine that I bought specifically for the holiday.

I could not finish a glass the taste was very strong and it just didn’t feel right.I’m 116 lbs so 2-3 glasses of wine would be enough before wellbutrin. Now, I can’t even finish a glass. The next day I was nauseous and had a terrible headache and felt sad and depressed. It’s not worth the risks besides we all know alcohol is a depressant the very thing that we are trying to get rid of.

November 30, 2008 at 2:44 pm
(75) aracely says:

I’ve been on wellbutrin sr for almost three months I’m on 300 mg and I had been avoiding any type of alcohol consumption due to the risk of seizures. Yet, on Thanskgiving I decided I was going to try a new wine that I bought specifically for the holiday.

I could not finish a glass the taste was very strong and it just didn’t feel right.I’m 116 lbs so 2-3 glasses of wine would be enough before wellbutrin. Now, I can’t even finish a glass. The next day I was nauseous and had a terrible headache and felt sad and depressed. It’s not worth the risks besides we all know alcohol is a depressant the very thing that we are trying to get rid of.

November 30, 2008 at 2:51 pm
(76) aracely says:

The bottle specifically says Do Not Consume Alcoholic beeverages while taking this medication. Therefore, even if your doc does not warn you about the effects of wellbutrin and alcohol the bottle does. The warning is there for a reason it’s better to be safe than sorry.

December 3, 2008 at 8:39 pm
(77) Chris says:

I can confirm that even two or three drinks -in the evening in my case- along with anti-depressants -in the morning- were enough to bring me back down to the old negative attitude very quickly. It also disrupted my sleep pattern and clouded my thinking for a couple of days so that I felt pretty useless and guilty, and of course that’s not what we want when we’re fighting depression.

I finally completely stopped drinking, and it makes a world of difference. I had stopped drinking before between 1992 and 2006, and have been taking anti-depressants since 1996. These two years of combining drink with medicine have shown me without a doubt that it was a losing proposition. Feeling fine again and staying so means, at least for me, the definitive end of substance intoxication.

December 18, 2008 at 8:33 pm
(78) kat Bode says:

I have friends on Well who drink like fish.. they are fine..I started two days ago but I am not taking it anymore if I can’t have cocktails.. How boring..

I am trying to exercise more and take muliti’s with energy boosters.. I say NO to Wellbrutrin and try something else that you can have alcohol with.. or try acupuncture or herbal remedies..

December 20, 2008 at 5:23 am
(79) Kwork says:

A special thank you to Pam for sharing her blurred eye experience. When it happened to me I called eye doctor who told me it was serious and I should get there as soon as possible. After considerable testing he could find nothing, so referred me to neural opthalmologist. What a pain, travelling to meet his hours, waiting, filling out forms, etc. He could find nothing wrong so recommended an MRI. Again, time, distance,forms,etc. An extensive MRI found no reason for blurred vision. All shrugged and said, fortunately nothing was wrong w/me, but had no clue as to what brought it on. You’re fortunate you didn’t get processed by med establishment. Thanks to your posting, I feel problem arose from booze/Wellbutrin.

December 20, 2008 at 5:30 am
(80) Kwork says:

Thanks, Terrified. I belong to same club. Drink until groggy, take nap, wake up drink some more, morning/noon/night. I now also will leave 2 time refillabe almost full Wellbutrin container in medicine cabinet. Didn’t realize risk of seizure.

December 25, 2008 at 7:19 pm
(81) Mike says:

How long do you have to be off wellbutrin before you can safely drink?

Ive been on WellbutrinXL for about 6 weeks and have not drank any alcahol since I started it. I have not noticed an improvement with my depression and anxiety so I have decide to stop the Well and to drink again – moderately. But I find no Info on how long it takes the Wellbuterin to be out of your system before you can drink safely. All the bottle says is “Avoid drinking alcahol while taking this medication”. Well that could mean dont wash the pill down with Jack Daniels or wait for a year after discontinuing it. Does anyone have an answer for this?

Thanks In Advance!

January 4, 2009 at 7:17 pm
(82) roger says:

i have been taking wellbutrin for a few months now and the other night i went drinking and had 5 or 6 beers and im a pretty big leightweight so i was wasted. it is now day 4 and things seem a little blurry still and im pretty worried that its not gonna go away. will it? please help

January 4, 2009 at 9:55 pm
(83) a says:

hey roger dont worry same thing happened to me new years night, i had about 10 drinks and felt mentally clouded for the past couple of days but now im starting to feel better. hope you feel better too

January 5, 2009 at 3:13 am
(84) Tilley says:

I am glad I found this site. My experience has been the same as many of you. I get drunk very quickly, I blackout, and for several days after am in a deep depression and dwell on all the stupid things I did while making a complete idiot out of myself in public. I just want to be a “normal” person but cannot live without antidepressants.

January 8, 2009 at 8:55 pm
(85) esp says:

wow. i never pay attention because most prescription drugs say no alcohol. i’ve just started taking 150mg of the XL after a few months break. I drank for the first time last night and got much drunker than normal and today am much more hungover than normal. i remember last time my doc upped my meds to 300 and i tried to cut myself and jump out the window. my bf literally had to hold me. until i’ve read all this I thought this was just in my head. thanks

January 9, 2009 at 1:15 am
(86) AmyD says:

I want to add my thanks to all those who have posted their experiences here and made me feel that I wasn’t alone in this, or that my Wellbutrin wasn’t working. Yep, I am on the second day after having 6 drinks, and I am depressed and irritable. I was all set to call my Dr. to up my appointment (in a week and a half), but I think I’m going to just avoid alcohol altogether until then and see if it makes a difference. I too had WICKED hangovers after 4-5 drinks but didn’t realize that the alcohol was causing the breakthrough depression so many days later. I was used to drinking pretty heavily but agree that it isn’t worth it to have a few hours of fun, to feel so shitty days later. I again, am eternally grateful to this site and all of you for letting me know that this combo could be so bad, and that it could last for as long as it has. I thought that I was going to have to start all over again with a new med, but I hope it’s just the booze!

Also, to Jackie #51-I too experienced huge “waves” of rage when my Dr upped me from 300 mg XL to 450 mg. I told him and got it dropped and that hasn’t happened again unless I’ve had a few drinks. I don’t know if this is the case with you, but if you’re still having this it might be in your best interests to see if your Dr wants to lower your dose.

January 11, 2009 at 10:18 pm
(87) Ann says:

I drank last night – way too much – and now after reading this site, and how I feel today, it makes sense. I will never drink again while on Wellbutrin.

Mike – are you on the brand wellbutrin or the generic? For some there is a difference so before you quit taking it, you may want to talk to your doctor.

January 21, 2009 at 2:04 pm
(88) Yankee says:

Like most of you I get very easily drunk now that I have been on Wellbutrin for 9 months. Binge drinking (at parties…I only sip red wine at home) can cause me to have fragmentary blackouts, and to display inappropriate behavior that embarrasses me the next day, which is very unusual. I have always been able to “handle” my liquor, and I’ve been drinking since age 17 (now age 36).

I have depression, but my main disorder has always been anxiety. I switched to Wellb because SRIs take away my sex drive, which is absolutely not acceptable to me, and I thought I’d give Wellb a shot. I don’t know if anyone else has experienced this, but I’ve smoked weed for 18 years to relax and self-medicate my anxiety, but since being on Wellb I get HARD CORE paranoia and anxiety if I do that. My heart is beating a mile a minute and I seriously feel insane until the weed wears off. I decided to give up the weed a few weeks ago and am doing much better.

I can sip 8 to 12 oz of red wine thoughout an evening without getting crazy drunk, but after reading these posts I’m wondering if my listlessness and lack of desire to do anything productive is because of drinking ANY amount of alcohol while on this scrip. I have always been a motivated go-getter, but I have noticed in the past few months I can stay indoors all day on a weekend and never leave the house. This forum makes me suspect there is a connection.

I think I am going to be “clean” (scrip only) from now on. Big life change for me!!!

Hopefully this info helps someone.

January 23, 2009 at 1:47 pm
(89) bridge says:

i’ve been on wellbutrin and lexapro together for a couple years. I really don’t have any bad side effects at all and i still enjoy drinking while on these medications. I say try it and if it is bad for you then don’t continue to drink. But not everyone has to stop drinking while on these medications.

January 27, 2009 at 9:25 am
(90) mick says:

I myself have been on and off wellbutrin for 2 years. I stopped a year ago but recently have gone back on it starting the new year. Like most people i find myself slightly more sensitive to alcohol. The main issue is that when taking wellbutrin and i have alcoholic tendencies. I’m a moderate habitual drinker but the mechanism in my brain that says enough is enough just doesn’t function when on the meds. The more i drink the better i feel. After an embarrassing experience where i blacked out and friends had to carry me home I learned to consciously control my alcohol intake.

Another strange thing is that once I refilled my prescription with a generic version of the drug I have started to notice some side effects of fatigue, headache, irritability. I’m not sure if it’s coincident and I might have a virus or something or whether there is a difference between generic and brand

February 1, 2009 at 3:39 pm
(91) DGinAustin says:

I am a 44 yr-old woman and in my life have never taken any medication other than aspirin–I hate taking pills. A week ago I was prescribed WB/300mg for smoking cessation and mild depression: a feeling of being flat, no interest in anything and a sense of being disconnected from people and life. After day 3 a noticeable side effect was that I was conscious of my heart beat and found it difficult to fall asleep and sleep soundly. I felt a little lightheaded and out of sync. Maybe due to lack of sleep? I’m probably a little older than most on this post, but still like to party on the weekends. Friday night is my one night to binge and it’s almost always white wine with an occasional shot of tequila. In the course of six hours I’ll drink one bottle and depending on the conversation and food, sometimes 2 bottles of wine. I can’t remember a Friday where I did not drink wine. I have never blacked out nor have I ever been out of control or behaved so badly that I was embarrassed the next day. I am always in control and know when it’s time to stop and go home. This past Friday was day 5 on the WB. After one bottle of wine, I felt hyper, sort of nervous and I was nervously using my hands to over-animate as I talked. When I did talk, my head would involuntarily shake side to side like someone with Parkinson’s disease. When I did speak, my words would come out jumbled and mixed up. I could not form simple sentences and since none of my friends know I am taking WB they would laugh it off and imitate me. I didn’t know I was mixing up my words to that extreme. It was definitely time to go home. When I announced that I was leaving I said to everyone “It’s go to leave for me” or something like that. It really scared me. The next day, I had a mild hangover and also had mild body tremors and involuntary muscle jerks and a nervous or anxious feeling all day. Today, I feel a little better but notice that I don’t feel 100 percent yet. I do believe my days of weekend binge drinking are over while taking this medication. As far as the smoking cessation, it is too early to tell, but what I do notice one week into taking WB is that 4-5 hours will pass before I realize I haven’t smoked, didn’t think about smoking, and I didn’t have the desire to cave in and have one. For me, I am going to stick with the 30-day trial period and follow-up with my doc and re-post. Being an ex-smoker and feeling better emotionally and socially is far more important to me than drinking. Thanks to all who share their experience. It educates us all in some way.

February 2, 2009 at 3:46 am
(92) erica says:

i have been taking wellbutrin for three months, and recently after drinking a bottle of wine i snapped for no reason and i assaulted my boyfriend. i was out of control, and i am usually a happy drunk… not this time. i have only a vague recollection of the events of that night, but i am still paying for it. our relationship is over and i feel kind of cheated because violence is completely out of my nature. i don’t even know what happened.

February 4, 2009 at 7:45 pm
(93) Kyle says:

I was just prescribed wellbutrin 100mg sr. I am a serious drinker. Drinking a 6 pack a day with a shot or 2 of whiskey mixed in there. I have no qualms about quitting..it would be good for me, but I am reading that one should not “abruptly” stop drinking when prescribed wellbutrin so as to avoid seizures. So what should I do? slowly ease off drinking? Stop completely? Continue full strength. I just want to get better.

February 6, 2009 at 4:45 pm
(94) kevin says:

ok so i have been taking Bupropion for five days. i basically was seriously drinking almost daily since july, now it’s feb. my life fell apart and my “girl” told me she was pregnant from another guy as a christmas present. basically i was major depressed. i took prozac years ago but it made me just even.. if i won the lottery or was hit by a bus they were both the same amount of apeal to me. so 12 years later i decided to try the anti dep. meds again, but i adamantly refused prozac. basically i have had 3 things happen. first i got my script at like 7 pm on monday and was told it may make me not sleep so i waited to take it till tue morning. i ended up staying up all night monday and took my pill on tue morn. after about 40 hours of being up and 6 hrs after taking my pill (150mg) i had a totally weird experience. it was like i was trying to puppet my body through a tunnel i sort of zoned out, but i was still there(not missing time) but i was far away from myself. it lasted about ten min and stopped and hasn’t happened since. 2 i feel happier, even though i know it is supposed to take month(s) to get the benefit(s) from this drug, my smoking is the same. 3 i drank about a 12 pack last night, i was ok but this morning i just felt like hell. i haven’t had a hangover in years so i didn’t associate the feeling, but a headache, no energy and a lack of motivation or interest. before i began this med i had a few psychotic episodes while drinking, mostly anger involving a relationship, and blackouts where i would be told later by others what happened, i basically lost all my friends this way. so i am concerned about the potential for blackouts on this med, but i haven’t had anything yet, and if i feel like this ALWAYS after drinking it may be what i need to stop! i’ll update if i have any other strange experiences. has anyone else had the puppet zone out thing?!

February 10, 2009 at 10:00 pm
(95) Luke says:

I started taking wellbutrin XL in november of 2008 and am still taking it today. I continued to binge drink pretty heavily same as before I started. My doctor advised me not to but I did not really care. Honestly I don’t think it really effected me. I always black out and can’t remember the night anyhow.

February 10, 2009 at 10:19 pm
(96) jessica says:

I’ve been taking between 150-300mgs of wellbutrin for five years, sometimes with effexor. I don’t drink a lot, but I’ve had no change in my response to alcohol. I’m starting klonopin this week though, so I’ll tread carefully.

February 14, 2009 at 1:05 pm
(97) tyrone says:

I have been on wellbutrin 150mg for 6weeks. decided to drink. Cant rememeber half the nyt which is unsual on my behalf. quit smoking since been on it. Smoked alot. Almost got it punch up for no reason whatsoever. my fault. Was uncontrollable. felt on edge and like “no where” the entire time. Got chucked out of the club by police officer, almost got arrested because I ran my mouth. Got home and decided to snort 2tabs. Messed me up totally. Peice of advice, just dont mix these two. Rather do drugs with this AD than drink. It is very weird feeling, and uncomfortable. I read these posts before I drank but decided to still go ahead. U probably wont take this advice, so learn the hard way and I hope nothing serious happens. Good luck

February 15, 2009 at 3:12 am
(98) kyle says:

Anyone have an answer to my question above?

February 16, 2009 at 3:46 am
(99) heyyou says:

i think you are supposed to wean off of the alcohol. just like starting a med. cut down slowly, like a week at a time and then taper off completely.
after 2 weeks of 300 the doc upped me to 450 because i suddenly felt like life was hopeless and empty, so confused about my future and feelings. which is strange. i started for stress and to quite smoking. I didn’t realize that my 2 beers a night and the stuff was the reason i had such a hard 2 weeks. it was awful. i feel better on the 450. just had 3 beers tonight, only thing alcohol has done to me with wellbutrin is make me want to have sex, but yes the next day i feel like life has no meaning, wich is scary.
as for the smoking, i have been a smoker for 7 years. every 2 hours no matter where, i had to have one.
i am now down to 3 a day and that is AMAZING for me. it takes away the thoughts of smoking….so great

February 16, 2009 at 1:21 pm
(100) Kyle says:

Thanks. I had done just that. 6 Beers then 5, the 4 and so on to just a small glass of red wine a night. Then last night I went to a show and since I had no answer I had a couple drinks. Exatly 2 Ketel 1 and Tonics. Got home and then had a few more. I woke up and felt like I had been hit by a bus. I feel really really, down today. I am just going to avoid alcohol completely from now on. It’s not worth it for me. It hurts to type this. I want to curl up in a ball and cry.

February 18, 2009 at 11:15 am
(101) Nick says:

SOMEBODY PLEASE HELP ME. Okay, so I recently went on Wellbutrin 2 months ago. Since then, I’ve been drinking about 4-8 beers every saturday and sunday with minimal side effects. THEN, last saturday I drank 12 drinks in an 8 hour time span, got really drunk (didn’t blackout), and acted semi-crazy. The next day I felt like complete SHIT. This is now day FOUR and I had to take the day off of work. This is not a normal hangover and it is not getting any better. I am dizzy, light headed, have blurred vision, semi-confused, semi-crazy, lathargic, unpersonable, can’t concentrate. Has anyone else heard of this? PLEASE help!! I don’t want this to last forever because it really isn’t getting better and it’s been four days.

February 21, 2009 at 11:46 am
(102) SJ says:

I just started taking 150mg of Budeprion and had no idea about the alcohol combo. I weigh 120lbs and am fairly sensitive to alcohol as is, but last night I only had 3 cocktails over the course of 4 hours. I remember feeling a little anxious then, but this morning I am soooo dizzy and have slightly blurry vision. I still feel drunk! I was planning on going out to a Mardi Gras party tonight, but after reading this I’ll definitely keep it to just one from now on! Thank you!!!

February 23, 2009 at 1:47 am
(103) Dana says:

I’ve been on Wellbutrin for around 2 years now, but in the past two weeks was sure it was wearing off. Now I’m not so certain. I don’t even remember the different anti-depressants I tried before settling with this one because my depression was so dark. And I felt it returning! That don’t want to wake up, get out of bed, leave the apartment, go to class, feeling. The inexplicable sobbing because it felt like my body was being ripped apart. Just deeply, deeply sad and even suicidal at one point (I’ve attempted in the past). It’s scary. I still feel so down and unmotivated. I’ve also been drinking a LOT lately, and now I wonder if it’s a vicious circle. Drinking makes me depressed which makes me want to drink more. I’ll take a break from the bottle for a while. Never experienced blackouts or anything on 300 XL, but have had the invincible feeling. I’ll stay away from drinking and hope I feel less hopelessly depressed soon. I don’t want to scare my boyfriend, who met me after my depression was under control, away because of me bringing him down with me.

March 3, 2009 at 4:08 pm
(104) kate says:

This weekend i went to a party and drank… about 5-6 heavily loaded jim and sprites. Ive always been a big drinker. I also had a couple shots. Now usually this amount of alcohol, well im drunk, but not blacked out. Usually i can drink more. Now i blacked out a good 3 hours of the night. The things that i did that night were very… not me. ever since than, i honestly want to kill myself. i feel horrible, i have nightmares. My dreams alone feel 3 days long. I wake up every 45 minutes scared. throughout the day i get my dreams and reality confused. I cant concentrate, and am absolutely detached from the world. Im scared right now. i advise strongly not to, the dreams alone will haunt me for some time.

March 8, 2009 at 4:00 pm
(105) Audrey says:

I am so relieved to have found this thread. I have been taking Wellbutrin for about 10 weeks. I’m a freshman in college, and I’ve started drinking on the weekends with friends. I noticed that I was extremely emotional some nights after drinking. I totally flipped shit on my best friend for no reason last one night while walking to the dorms. But today, I am experiencing the most awful feelings. I can’t focus. I can’t form thoughts properly. I have a 3 page essay due tomorrow, and I’m about to breakdown. I drank on Friday night, and like most of you, became very drunk after only drinking a little. Last night at 9, I became extremely anxious before meeting up with a guy. I was completely unable to calm myself down. I still went out, and we drank wine. I was tipsy and shaky and could hardly express myself. But now, I can’t snap back. I can’t even function. I can’t form thoughts or focus. I’m glad I found this blog. I’m so mad at myself for not reading the label, and not listening to my counselor. I thought I was having panic attacks, but now it makes sense.

March 11, 2009 at 9:53 pm
(106) Matt says:

Interesting stories! I’ve actually been prescribed 600 mg of Wellbutrin per day with a few occasional 20mg adderall pills every so often. My body has a high metabolism. I’ve been taking Wellbutrin XL for about 2 years now and everything was fine up until about a few weeks ago. I’ve noticed that my drinking has increased recently (0 beers to 2 to 4 beers and a few shots of whiskey), due to the stress levels in my life.

Over the last month, I have been loosing out on more and more sleep and have become more and more stressed out from work. Several weeks ago, I took my regular dosage of wellbutrin xl and Adderall throughout the duration of the day, came home had about 4 beers, ran my usual 4 miles for the day, took my last dosage of wellbutrin xl for the day around 10 pm(totaling 600 mg), and at that point, I fainted and started feeling extremely dizzy and light-headed and called the Poison Control Center. After speaking with them and finding that everything should be okay, I started seeing spots in front of me and I began to feel really weak. Eventually, I had to have my girlfriend call 911. At the time, I was scared to death that I was going to have a seizure or god knows what. The paramedics hooked me up to all of the emergency medical equipment and found that I was going to be okay after all; however, I was advised to call my doctor immediately. The paramedics told me that a seizure is usually caused if you keep popping those pills just one after another; however, that was not my case. Anyways, I spent the rest of the night drinking water and pissing that stuff out. Needless to say, the following day, I felt like crap and could barely function at work (Thank god it was Friday).

After the incident, I went off this stuff cold turkey simply out of the fear that it instilled in me (no telling how my body will react to it again when and if I take it). My doctor has prescribed me Lexapro now … we’ll see how this goes …

I just wanted to post a WARNING to those who take high doses of this stuff and ingest alcohol along with it. Don’t do it! And get plenty of rest as well!

March 12, 2009 at 8:24 pm
(107) Loren says:

Ok, I’ve read most of these comments and I have to say I haven’t read one that described what I went through.

I take 300mg. of Well. and 20mg. of prozac to treat my depression. Up until just now I didn’t know how bad the side effects CAN be when mixing alcohol. I’ve been taking well. for a few months and I’ve been drinking moderately (as I always have). I did notice last Fri. a HUGE difference. Quite bizarre. I went to the bar with a few friends and ordered what I always do (double vodka/tonic), I finished it, didn’t feel anything, ordered another one. USUALLY if I have two double vodka/tonics in a night….I’m good for the remainder of the evening. However, this night was different. After finishing my second double vodka/tonic, I waited a little bit, and to my surprise, still didn’t feel anything. No buzz, no sense of feeling happier, I could have been drinking fruit juice all night. Soooooo….I had a shot of tequila, normally after all this alcohol I would be drunk off my ass. But guess what? after that shot…still nothing. So, I’m starting to wonder what the hell’s going on and I think it’s kind of funny. My friend THEN ordered my ANOTHER shot of tequila! 30 min later….NOTHING! What came next? An irish car bomb…..and yes, you guessed it, nothing. I had never felt so sober. I was in complete disbelief. Like I said, normally 2 double vodka/tonics OR two shots of tequila, over the course of the night would have been just fine. Btw, I’m 25, female and about 180#s.

I definitely notice a difference in hangovers though…not good. Also, after reading I DO feel worse for a couple days following. I just thought that was interesting, has anyone else noticed a DECREASE in alcohol sensitivety?

March 22, 2009 at 2:36 am
(108) Mladen says:

I’m taking wellbutrin for the second time in my life.. just started a few weeks ago again. Totally agree to watch the combo with alcohol. Personally it makes me manic, and prone to extreme outbursts of anger and rage. I’ve done some crazy things while mixing the two. Be careful.

March 24, 2009 at 3:21 am
(109) susu says:

I’ve been taking Wellbutrin SR 150 mg a day for the last 6 months due to depression from career burn out. I drink about 3 glasses of wine a night, sometimes 4 — I have not noticed much of a different effect, except that I feel like I drink more now than I used to because it’s harder to wind down from the speedy effect of the Wellbutrin. When I increased my dose to 300 mg (when I first started the drug) I had a complete psychotic episode (with no alchohol). Wellbutrin is a very strong drug, and while it cures the depression, I feel that it’s made me less sensitive/empathetic in general. Hard alchohol definitely seems to have a much, much stronger effect as well. I’m super athletic, so I would imagine that for people that exercise less the effects of the alcohol the next day or 2 without sweating could be much stronger.

March 25, 2009 at 10:31 pm
(110) JT says:

Like most, I’m glad i found this site. For 4 years i took wellbutrin then switched to 20 mg of celexa. While on celexa, had an increased desire to drink but was always a happy drunk. Due to the weight gain, i asked doc to put me back on Wellbutrin. Well, i can assure you there is a big difference in the affect for me. On the same amount of alcohol, i get way hammered, not a happy drunk and am useless for two days. We all must remember, for those of us who take AD for depression, alcohol is as depressant. What do we think will happen????? Be careful. No more for me. Do your research because most of the docs are clueless as to how we feel.

March 28, 2009 at 1:06 pm
(111) Katie says:

Wow I’m so glad I found this because just last week I had a pretty shitty thing happen. After work my boss came and gave me wine and after just 2 glasses I went into and out of a blackout all night, could barely walk, blurred vision, etc. My boss who’s 50, married, and has daughter older than I am took advantage of me. I thought he mightve put something in my drink because normally to feel as fucked up as I was it would take 9 or 10 shots. I don’t recall if I agreed to go upstairs in the restaurant or not.. I was pretty messed up. I guess it’s not his fault though if my meds kept me from being able to say no.

October 15, 2011 at 4:41 am
(112) annie says:

I know this comment is kind of old but no matter how drunk you were or what drugs you were on its NEVER ok for someone to do anything sexual with you. It’s actually illegal. You cannot legally consent to sex when you are drunk or high or whatever! Your boss is an ass and should go to jail. I hope you are doing ok now.

April 1, 2009 at 7:23 pm
(113) Angela says:

i just started taking 300 mg of wellbutrin and .5 mg of klonopin a little about a week ago. i plan to drink this upcoming weekend. should i worry?

April 9, 2009 at 10:36 pm
(114) Daniel says:

Jeesh. I just started taking Wellbutrin about a week ago. This past Sunday night I went out and drank a fair amount. Not an unusual amount for me as I have a high tolerance and have been a somewhat heavy drinker on and off for a long time. Anyway- I ended up completely blacking out. I don’t remember where I was- where I was going. My seconf to last memory was being at a bar and ordering another beer. My next memory was being handcuffed and put in the back of a police car and taken to the drunk tank at our local hospital. THIS HAS NEVER HAPPENED TO ME BEFORE. I have never blacked out and I’ve never been arrested. Thankfully I did not make it back to my car. I vaguely remember trying to kick the door of the cell open and then nothing until about 11 am the next day. I found this site because I’ve been looking for info to explain this behavior. I utterly embarrassed and every time I see a cop (like in the restaurant I had lunch in today) Im worried they recognize me as the psycho from Sunday night. Anyway- I am relieved to read your stories…thanks for sharing. I quit drinking btw.

April 10, 2009 at 1:36 pm
(115) Daniel says:

When I first started taking Wellbutrin it was 150 mg. Around the second week on it I had ONE beer and immediately started having tunnel vision and tingling in my hands, fingers and legs. I haven’t drank since. I had never felt that sensation before and am afraid it was a precursor to a seizure.

April 24, 2009 at 4:09 am
(116) Lisa says:

I am on wellbutrin now for about a month. From the first day that I took it my depression went away and my binge eating stopped. I had a ton of energy… The side effects were beginning to subside enough to tolerate when I went out until this past weekend. I drank alot…a few shots, a few mixed drinks.. I didnt get any more drunk than I would have before being on wellbutrin, and I didnt black out or throw up. However, starting the day after (Sunday) up until today (Friday) I have been extremely depressed, lethargic, I locked myself in my room, wont answer my phone, cant derive any pleasure from anything, cant work etc…the medication stopped working. And to boot starting on wednesday I started to feel like I was going through the residuals of opiate withdrawal! I went to my doc and she upped my dosage to 300. I didnt know if I wanted to do this because in the past when I drank (not as much) the medication only stopped working for a day or two maybe three but then it started working again like normal. I thought it would be the same thing again this time…boy was I wrong. My pharmacist said basically the drinking wiped out all the stores of the medication that my body had built up and thats why I was feeling like this. That I should keep taking the higher dosage until I build them up again (the 300 will do this quicker than the 150) and then once I feel better again if I want I can come back to 150 since I was doing well on it before. Im just starting to feel better today but this week was a horror show. Obviously I cant drink on this medication. I’m not sure if the pharmacist is completely right or not because I think the drinking messed up my dopamine system possibly depleting alot of my dopamine or desensitizing or screwing with the neurons or receptors. Just letting people know my experience so that it can help you learn without having to go through this nightmare.

April 25, 2009 at 8:37 pm
(117) Girlygal says:

I’ve been on Wellbutrin XL for over a year now. I’m only in my 20′s and weigh 138lbs, so I guess you can consider me a light weight, seeing as how prior to being on the drug it only took a couple drinks to feel pretty drunk. Since taking the medication it literally takes a beer or two to feel drunk. At times I feel very concerned what of could happen to me because not many people know I take Wellbutrin. Unfortunately, I don’t think I would be able to function without it.

April 29, 2009 at 3:34 am
(118) Studioforce says:

I am on 100 SR and i’ve been taking welbutrin for a while now. I have noticed EXTREME depression the following day. The hang over sysmptons of lessened but the depression is always there. I realized the hangover connection but that the depression. It’s not worth it to experience that. I can’t imagine drinking at 300mgs. Some of you are really pushing it. I’m 230lbs 6’4 body builder… I can’t imagine how it would effect you.

April 30, 2009 at 11:27 pm
(119) Cuteshoes says:

I have been on WB XL for 2 days for mild situational depression and I have a first date next Tuesday (5days) and we are going to a wine bar. I only plan on drinking 2 glasses if wine. Should I either not drink at all or not take the WB for a few days. I am not a big drinker. Maybe 2-3 glasses of wine once or twice a month…if that. No other drugs or anything. I need help quick!

May 2, 2009 at 8:13 pm
(120) Casey says:

ok i have been on wellbutrin for about a week now at 150 mg. Went out last night with a friend and we shared about 3 pitchers of beer. This morning i woke up thought the world was going to end. Hangover from hell. Still at this point at 8pm iam still not the same. I have had dizziness, shaking, flush face, twitching, not very hungry symptoms. I have learned my lesson and will not drink on this medication again. It really does not mix at all.I can say though that it has begun to help me quite smoking though. i went from a pack a day to at least half a pack already in one week. Tomorrow i am suppose to increase my dose to 300 mg. Unsure if iam ready for this.

May 4, 2009 at 12:22 am
(121) theo says:

i just got on wellbutrin and could use some feedback from you guys. I’d taken Lexapro for a while, but it was barely working okk, so the doc and i agreed Wellburtin would be worth trying for me.

I like to go out w friends and party a bit. The first time after I took wellbutrin 150g was a big bash, so I threw down quite a few drinks and went swimming in a pool. I was drunk, but no differently b/c taking wellbutrin . I also got very hungover, but fine.

Then the next week was the 2nd time: my birthday party in Tribeca. I drank more than the previous time, things happened that shouldn’t have that i don’t remember and i woke up at a girlfriends place that I didn’t remember going to. But, I’d been legitimately soused. I have never not remembered so much of an evening like this one. The doormen at the building forced me to leave later in the morning even though I wasn’t a part of the fight that had taken place at their bar the nght before. And the hangover was worse this time, but more in line w the amoung i drank.

The 3rd, and maybe last time I drank booze while on wellbutrin, was last nite. I told myself I would not drink much, just one wine or beer with a light dinner and my date ate lightly, too. I felt ok, really, just with drinking very moderately. A beer or one wine and that would be it. But she told me that when I crashed at her place the 2nd night above, she got pregnant. She wants to keep the baby.

The botton line for me: I should have realized to take it easy on nite #2, not night #3. So I wonder if Wellbutrin can also affect your judgment in conjunction with alcohol. WHile I liked Darah enough to date and fool around with, i sure wasnt’ ready for this to happen. I don’t like to blame things, but if it weren’t for the Welluburtin I would not have come close to that and have another set of issues to seal with. So maybe I will just do the right thing, propose to Dara and then this will be a good kid, the first of mnay SO THANK you Wellbutrin, just keep me from other girls ready to get impregnated.

May 4, 2009 at 1:53 pm
(122) meredith says:

i’m really glad i found this thread! i was just prescribed wellbutrin for depression & anxiety (i’m already on prozac). like most people my age (24), i often go out & drink on the weekends with friends. i already get extremely tired (i’ve fallen asleep in bars more than once) and depressed while drinking, plus my social anxiety comes back worse each time. reading everyone’s reactions to alcohol & wellbutrin has just solidified my decision to cut back even more on my drinking once i start taking it. i’ve dealt with blackouts & not knowing how i got home in the past and i’m not looking forward to dealing with those again.

plus…i always have more fun watching everyone else be drunk while i’m soberly laughing at them :)

May 10, 2009 at 12:44 am
(123) Corina says:

I have been on 300mg Wellbutrin XL for about 6 months now and have noticed a big difference in my reaction to alcohol.
I can have 3 glasses of wine and not feel any alcohol effects and wake up with a horrible hangover.
I also can not feel physically buzzed or drunk and have random moments of blackout or horrible emotional (mostly crying sometimes rage episodes) out of nowhere.
While I will still have a glass of wine at night, the “joy” of drinking is gone.
I think the best bet is to try and steer clear of alcohol while on this med!

May 11, 2009 at 1:29 am
(124) Thatgirl says:

I have been taking 150mg of Wellbutrin for almost a month now for my anxiety and depression. I consider myself a heavy drinker. I am noticing now when i drink i become drunk very fast and have a horrible hangover the next day. This past Friday i went and drank with a friend. I then took 30mg of methadone and a lortab plus alcohol. I could not sleep. When i got home in the morning i took 1mg of xanax to help me sleep. I woke up after 3 hrs and then took my 150mg dose of wellbutrin and 30mg of adderall to help me wake up and study for finals. I was doing all of this and not even thinking about what kind of drugs i was mixing together and the effects it would have on me. I have been vomiting everything, suffering sever nausea, blurred vision, and stomach pains. I AM AN IDIOT! When i drink i make poor decisions and feel awful the next day, especially when mixing it with other drugs!

May 11, 2009 at 1:32 am
(125) Nat says:

I have been taking 150mg of Wellbutrin for almost a month now for my anxiety and depression. I consider myself a heavy drinker. I am noticing now when i drink i become drunk very fast and have a horrible hangover the next day. This past Friday i went and drank with a friend. I then took 30mg of methadone and a lortab plus alcohol. I could not sleep. When i got home in the morning i took 1mg of xanax to help me sleep. I woke up after 3 hrs and then took my 150mg dose of wellbutrin and 30mg of adderall to help me wake up and study for finals. I was doing all of this and not even thinking about what kind of drugs i was mixing together and the effects it would have on me. I have been vomiting everything, suffering sever nausea, blurred vision, and stomach pains. I AM AN IDIOT! When i drink i make poor decisions and feel awful the next day, especially when mixing it with other drugs!

May 27, 2009 at 4:46 pm
(126) Kimberly says:

I am so happy to have stumbled onto this thread. I have been off and on (mostly on) Wellbutrin (generic) for four years. Initially for smoking and now I notice that if I stop for a few days I fall into a deep depression. I am a wine drinker. It was nothing to drink one or even two bottles at a time. I started blacking out about 2 years ago. At first I would pretend I knew what had happened the night before just so no one would know. I then told my husband who is very supportive. I also flew into rages the next day…horrible sweats, racing thoughts etc. I just thought I was going crazy. Recentl yI went back to the Doc and he upped my dosage from 300mg to 450mg. I drank more last night than I have in a while and although I did not black out, I have had stomach cramps all day and have a feeling os listlesness and low self esteem. I never connected the dots between alcohol and this drug before. I think it is more dangerous to completely stop drinking. I am going to “step” down and hopefully just be an occaisional drinker. I am soooooo glad I am not alone!

May 30, 2009 at 11:35 am
(127) AC says:

I have been on 75mg of bupropion a day for about 4 weeks now. Last night was the first time a glass of wine made me very tipsy and the effect lasted for many hours — I was dizzy, as well. (Interestingly, I had a glass after being on for 3 weeks, but no impact, so I guess the medicine is fully in my blood stream now.) Anyway, be careful. I’m not sure I’ll have more than a glass of wine on this stuff.

June 8, 2009 at 4:18 pm
(128) Lindsey says:

I used to drink to get drunk when i was younger but that stopped eventually. I take wellbutrin, prozac, and triazadone everyday. One day I decided to have a couple drinks to relax after work. I ended up getting into a blackout, auto accident, dwi, and in a fight with two cops. Ive never been in a fight ever.Dont mix alcohol with pills

June 9, 2009 at 6:07 pm
(129) Meg says:

Anybody else have stomach issues? I have been on wellbutrin SR for years now, which i don’t actually take for depression but because it works in combination with my thyroid medication somehow (I don’t question what works). Anyway, I noticed that on wellbutrin often i will get really nauseous from not that much alcohol (i’m barely drunk but feel like i’m going to throw up). It didn’t used to happen pre-wellbutrin so i’ve always associated it with that. Just curious if anyone else had that issue. I also get drunk a lot faster on it, but I don’t any problems with depression afterwards or blacking out. The upset stomach thing sucks but not enough for me to consider going off the medication.

June 8, 2011 at 10:12 pm
(130) Jilly says:

I am interested in knowing why you are on wellbutrin with your thyroid meds…I have had to take thyroid replacement since removing my thyroid. I have never felt the same once on Levothroid. I absolutely cannot stand it…it messes w my mind; seems to cause depression; and I end up with chemical imbalances.
I, too, am on Wellbutrin to counter the effects of thyroid meds. Is this your case as well?

June 10, 2009 at 12:06 pm
(131) Jay says:

FYI, I have just started Wellbutrin for about 1-2 weeks now taking 150mg daily. I went out this past weekend with some friends and had about 6-8 beers, glass of wine, and couple shots of hard liquor. Ofcourse I was drunk but I was just normally drunk like I would be any other time. Is this because I just started on Wellbutrin I’m not getting the same side effects with the mixture you guys are getting? Also to let you know I have a naturally high tolerance against prescription medication and alcohol… just putting in my insight about this, wondering if anyone else had any same experiences.

June 13, 2009 at 2:01 pm
(132) Alexander says:

I seem to have the exact opposite effect than anyone else here is describing about Wellbutrin. When I’m on Wellbutrin, it makes it nearly impossible for me to get drunk, no matter how much I drink. I’m talking drinking to 40s of malt liquor, multiple shots, over the span of about 3 hours. Anyone else get this, or am I one of those few people who are experiencing an opposite side effect?

June 21, 2009 at 12:35 am
(133) Jon says:

I can still drink, but not as much as I used to. Up to a certain point (probably 6-9 drinks), I’m fine. Past that, I become very agitated and angry at everything and I’ve done some very stupid stuff in that state. I believe it’s the alcohol shutting down my reasoning “circuits” and after that the increased dopamine in my brain is more “active” or potent.

June 23, 2009 at 8:08 am
(134) David says:

I feel depressed and “foggy” after having any drinks while taking Welbutrin however I had the same effect while taking Celexa. My doctor switched to W from C in order to try and curb the foggy feeling but it didn’t seem to make any change. Interesting to read all of these posts. Everyone’s body is a little different it seems.

June 30, 2009 at 5:56 pm
(135) Vera says:

I have been taking Welbutrin XL 150 for over 3 years. When I drink I have no problems whatsoever. The only thing I noticed was that it takes a lot less alcohol for me to get drunk, which isn’t necessarily a bad thing if you’re careful. The day after drinking though, I do feel more down and feel very out of it and “fuzzy”. But this usually only lasts during the first couple of hours after waking. I would say it’s fine to drink with this medicine as long as you realize that the effects of alcohol can be amplified and that if you drink too often it could lead to prolonged depressive feelings.

July 5, 2009 at 12:53 pm
(136) Kim says:

It’s 4th of July, been on Wellbutrin for about 5 wks to stop smoking, hav’nt drank at all and I’m craving beers real bad!. Bought a 12 pack of heineken came home, found this site, read it and NO WAY am I drinking!!!! Thanks to all of you for posting this. You saved me from a bad experience. Since I quit smoking on this med, hopefully I can get off soon so cause I really miss my alcohol!!
Good Luck to you all!!

July 9, 2009 at 4:56 pm
(137) Ella says:

Hey, I’m about to start Weelbutrin and I’m nervous because I’m a college student and I like to drink socially. Does anyone know what would happen if I didn’t take Wellbutrin the day I know I’ll be drinking? Would it remove the effects of the alcohol/wellbutrin combo? Or would it make no difference?

July 16, 2009 at 12:22 am
(138) greg says:

My doc said not to try to compare to others. As you can see, if you read the stories, most of them were not good. I like to drink, too. But, I have agreed to stop while taking Wellbutrin.
Doc says that you are messing with the neurotransmitters that you are trying to help with the medicine when you drink.

August 9, 2009 at 4:06 pm
(139) Mystia says:

I have another horrible story with psychotic blackout.

I was on 300 wellbutrin as well as effexor for severe clinical depression.
I thought I had been slipped a date rape drug, but now I know the reason!
Due to severe depression, sometimes I would binge drink to feel better, so I knew I had a high tolerance, and never blacked out before even when drinking A LOT.
But after being on the medication for a few months, I went to a bar with a friend. I only had 3 beers. Apparently I was acting very strange, and when my friend was getting a taxi I wouldnt get in because I thought the taxi driver would kill me, I was crying and shaking. I’m normally a very logical person that doesn’t experience paranoia! Anyway, my friend got in the taxi with me and dropped me off on the main street a block away from my house. BUT I NEVER MADE IT HOME.
When I “came to”, it was 6am and I was at the beach, holding a dead rat. I was completely repulsed and thought I must be dreaming. :( I was extremely dizzy feeling and disoriented. I still had my purse with me (Thank gawd!) so I stumbled to a McDonalds and bought a coffee and sat there until I had the energy to take the bus home.
I live in a bigger city that has a lot of junkies that walk around all night. I could have been mugged, raped, or worse. When I got home I rested for a few hours, then went into the kitchen for a drink and fainted hitting my face on the counter and passed out for a couple minutes.

I only had three beers!! Usually this only gets me mildly buzzed!!!

On this medication I also experienced severe body tremors and went to the emergency room twice because it was so painful like I was possessed.

BEWARE. If you want to see if you can drink alcohol with this medication, do it when you are HOME and SAFE! Even a slow night at a pub could lead to a disaster.

August 15, 2009 at 5:11 am
(140) R says:

I started Wellbutrin about 2 weeks ago. I’ve found that for the past few times I drink alot, like over 5 drinks, I get extremely depressed and have crazy destructive almost suicidal thoughts. I havent been like that in many many years. I think its because of the alcohol? I never put it together but now I think thats why.

If anyone has input, please let me know.

August 16, 2009 at 8:53 am
(141) erin says:

take it from mystia, the previous poster— unless you want to wake up on a beach holding a dead rat, don’t mix your wellbutrin with alcohol. i’m sorry, that made me laugh but it’s no laughing matter.
i feel down the next day or so after drinking with vitamin W, and have had some serious psychotic rages from mixing them over the past ten years or so.

August 20, 2009 at 10:12 pm
(142) April says:

I just received my first supply of Wellbutrin today. From your experiences should I avoid drinking tomorrow night? I was planning on starting the medicine the morning after but do not want any extreme depression symptoms. This column has been very helpful!

August 21, 2009 at 6:45 pm
(143) John says:

I just got fired from my job today. I’m on Wellbutrin, and had too many drinks at a job function Wednesday night. I ended up acting crazy as well as strealing drink tickets and alcohol from the bar at the hotel. My career as a teacher is over.

August 28, 2009 at 4:39 pm
(144) Kevin says:

I’m on 300 mg’s of Welbutrin and 20 mg’s of Celexa. I’ve only been on the Welbutrin for about a month and have been drinking on the weekends. I do notice that I get a buzz faster than usual and after a few beers I don’t want anymore. I assumed this was because of Welbutrin’s “side-effect” that stops addictive thinking (it’s also prescribed for smokers who want to quit).

But for any of you out there who are freaking out I recommend taking it easy and having a few drinks at home before going out on it. See how it effects you and then go from there.

September 1, 2009 at 11:17 am
(145) bobbi says:

I am currently on 300mg Wellbutrin and 10mg Lexapro. I generally do not drink at all. This is the first time in a year since my son’s death. This past saturday night, I went to play poker at the bar and I usually just drink a diet coke, but that night I had the same glass size with JACK and coke… 7 of them from 7:30pm to 1:30am. With two shots of PATRONE…. tequila. I remember the whole night. I felt very happy (long time since I was happy) and I did not have any problems, although I was drunk.. no doubt. My husband got me home, gave me two ibuprofen and two dramamine and put me to bed about 3:00am. No headache, no vomiting, no seizures…. I felt really good Sunday.

September 2, 2009 at 11:50 pm
(146) Amanda says:

I am in college and am a pretty regular drinker. I started taking 300mg of Wellbutrin 4 weeks ago and have had some scary incidents recently. I drank some wine and had a vodka drink and blacked out, can’t remember almost the entire night. I had another episode that was worse- violent and erratic. I have never behaved that way. It is really scary but I would rather give up partying than have to deal with things like that happening again. I strongly suggest NOT drinking on Wellbutrin at all.

September 6, 2009 at 3:05 am
(147) jamie says:

I have to agree with most of the storys .I have had quite a few drinks and blacked out and let me tell u it was scary I even ended up in jail for my violent behavior I was so ashamed .I have been taking welbutrin for a year now I don’t know if I should stop taking it or not because of the side affects when I drink because for days after I lock myself in the house and get very depressed.I strongly suggest not drinking on this medication and if u like your drinks maybe talk to your doctor about something else

September 6, 2009 at 3:11 am
(148) JerryMocha says:

Ive been talking 60mg of Prozac (social anxiety and depression), for 2 years and just recently started switching to Wellbutrin. I currently take 20mg Prozac, 150mg Wel. I havn’t drinkin for months, and have smoked some pot while on Wel. which got me high but very anxious and restless. College is around the corner, so I’m bound to have some drinking experiences comming up, espeacially cuz I’m turning 21 in a couple months. I’m in a real pickle here trying to decide if I should attempt drinking or not, it would be so hard to just quit it alltogethor before I’ve even experienced legal drinking (bars, etc.). I’ve decided that weed makes me too anxious overall, but used to love the effect of loosing all inhibitions/ happy while drinking. I guess I’ll have to experiment n take it slow…it was great reading all these posts, nice to know I’m not alone here.

September 8, 2009 at 2:57 pm
(149) Jen says:

Hey guys this is no joke for real! I was taking Serzone until about 5 yrs ago. I switched to Wellbutrin XL and drinking was NOT a problem…at first. I worked at a bar where the management encouraged you to drink with your tables and it was never really an issue for the first couple of months but slowly I started noticing that I was getting drunk faster and faster and would completely black out sometimes. Its 5 yrs later and I can no longer drink ANY liquor..not even one drink. I will completely blackout and have said and done some horrible things when I was. I stick to beer only now.

September 10, 2009 at 4:49 pm
(150) Rachel says:

I, too, have had a problem with mixing alcohol and Wellbutrin, but haven’t seemed to learn my lesson. After drinking, sometimes I feel fine, but every few times I get violently ill. It seems unpredictable. Last night I had three beers and ended up vomiting all night and had a splitting headache. I wanted to die and still feel terrible. I missed work today.

I’m taking Wellbrutin 150mg and Celexa. On the Celexa alone, I didn’t have any problem with drinking. Now after drinking I find I am depressed and low energy for about 3 days afterwards. SO not worth it.

I do find I get drunk much faster than I used to. I recently got pulled over and was made to do all of the drunk driving tests and blow. I passed the breathalyzer test and the cops seemed really surprised. They asked If I had been taking any narcotics or anything (which I wasn’t). They let me go, but I was obviously acting drunk, even though I had very little alcohol in my system. If you take Wellbutrin and drink anything at all DO NOT DRIVE!

I have also had a few blackouts and psychotic episodes. The blackouts are particularly frightening. Fortunately I have always been with people that took care of me, but I am embarrassed beyond belief.

During one of my psychotic episodes I physically attacked one of my male friends for no apparent reason. I’m 5’7” and 125 pounds. He’s over 6 foot tall and weighs much more than me. I attacked him, we started struggling as he was trying to calm me down and I managed to knock him off his feet and tried to gouge his eyes out. Luckily he was able to flip me over and he sat on my back pinning me to the ground until I calmed down. I was also screaming at him, telling him he was “dead to me”. The people we were with were totally freaked out. In the morning I woke up and was like “WTF??. I remember acting out of control, but I felt like it wasn’t me, like a had been momentarily possessed or something. I still have no idea what provoked me. I was covered in bruises and had a long, deep scratch on my shin that I still have a scar from. No idea how that happened. I have since tried to apologize for my behavior, but that relationship is pretty much ruined. I can understand why.

I’m glad I found this discussion. Thank you for sharing your experiences. I think I finally realize I need to abstain from alcohol completely. Knowing it’s not just me helps. I’m going to print these posts out and re read them when I’m tempted to drink again. Good luck to everyone that’s trying to quit drinking.

August 6, 2011 at 5:36 pm
(151) Christy says:

I had two years of very similar experiences to all of these on this board. Sometimes I would drink a ton and not have any effect. Next time out I would drink a ton and have violent psychotic episodes. Next time I would cry hysterically and black out. This med is not good. Here’s what Im wondering. Everyone comments on not drinking with with med but not many have said that they will stop taking the med altogether. Its the med causing the problems, not the necessarily the alcohol.

September 16, 2009 at 12:35 pm
(152) Tara says:

Hi, my doctor just prescribed Wellbutrin 200mg. mainly for my weight….is anyone else taking it strictly for weight loss? Im afraid what effects are goin to be mentally….do u become dependent? Can you stop for a day if you know you want to drink and go back to it? What are side effects?

ANyway just throwing this out there since I have bottle in front of me and im scared to try it just yet so i guess Ill continue reading……

September 18, 2009 at 4:35 pm
(153) Joshua says:

So I started taking Wellbutrin XL for mild ADD/ depression. Been on 300 for about 5 weeks. Its been ok i guess.

There have only been a handfull of times i drank on Wellbutrin. Having read this website and the comments (fyi thanks to all for sharing!) I have been extemely careful with what I drank. When I drink its only been beer (sucks cause i was a big whisky guy) and tried my best to keep it to just ONE beer!

Of course, being a 220lb dude and a retired weekend warrior member, I thought I can handle being a rockstar again.

Big mistake.

It only took 4 beers. FOUR MOTHER F$@#@#R# Beers?!! I got mildy buzzed but really drunk–so far so good but then it began. I got a HUGE migrane headache–I had to go home and took about four advils. But little did i know the fun was just beginning. For the next 5 days I would be not only be lethargic and depressed but would be suicidal.

I’ve NEVER been suicidal like this for so long before. My head is still foggy. I don’t know what to make of it. Even during the days when i use to blackout (half bottles of whisky and beer funnels) I would be on my feet by know.

Four beers and My world is ending?? What the hell!! Its been nearly a week!!!!!!

September 24, 2009 at 5:12 pm
(154) anna_78 says:

first of all.. im not from usa, so my english is not so good. well… i have been taking wellbutrin 150 mg (+ zoloft 50 mg) for 3 weeks now. before that i was just on zoloft. after adding wellbutrin i started to feel much much better, really. first week i had headaches and loss of appetite…. i had (still have) a lot of energy during the day, but at night i get soooo sleepy (no sign of insomnia like they are saying).. and i am sleeping really good, like never before. about alcohol… before wellbutrin i was drinking quite a lot (a bottle of wine, 3 or 4 times a week). so… first i was wondering… am i a regular drinker (so i shouldnt stop drinking abruptly, like i was reading, or what??!)? anyway… i tried a glass of wine first week… i felt really strange. in few days i drunk 2 glasses… i was a little drunk already… then slowly 3, 4, 5 glasses… and i felt okay. so now i can drink a little more. but still i dont want to drink so much as i did before. i dont even need that so much anymore. after reading all your comments i was a little scared…. but my experiences with wellbutrin+alcohol are okay. for now :)

September 28, 2009 at 11:36 am
(155) gradstudent says:

i started wellbutrin about 4 weeks ago at 150 mg per day. it was a different AD med from the prior cilexa, so i hoped it would work and give me what i needed. second week, Dr. and i agreed to bump it to 300 mg a day. lo and behold— i came out of my 8 month slump! i was energetic, enthusiastic, encouraged, and most importantly able to FOCUS and PRIORITIZE my life as a new doctoral student. :)

i’ve always been a drinker and never had a problem with alcohol and my prior AD meds (whether it was lexapro or cilexa). usually, a couple beers through the week and some mixed drinks on the wkds. no hangovers, no headaches, no black outs, etc. when i started the Wellbutrin, my mother, a nurse, warned me of the dangers of mixing alcohol with welbutrin. so i layed off. in the past month, i have only drank one time- at my father’s wedding reception. unfortunately, i drank beyond what my new alcohol tolerance allowed for (around 3 drinks, and too close together). i had a little hangover the next day…but no interaction with the wellbutrin. i continued my dosage as before, no alcohol either.

about 6 days after my little episode at the reception…i had a seizure while shopping at office depot for a new printer for my lab at school. no warning. no dizzy, nausea, faint spell, nothing…just a fade to black and i woke up in the ER of the local hospital like 6 hrs later. :(

now, the Dr. is mixing lamictal, an anti-seizure med into the concoction. although, you can bet i won’t be drinking for awhile. in addition, i had low blood sugar as indicated by labs run at the ER. eating correctly is also a part of the picture now. we’re not sure what was the direct cause of the seizure- excessive drinking a week earlier? low blood sugar as a result of lost appetite? :\

October 5, 2009 at 12:01 pm
(156) spencer says:

Hey guys, I totally agree about the alcohol part. I tried to drink a single glass of wine but it seemed really strong and I couldn’t even finish it. This may seem abit off topic, but I seem to be having very abnormal dream and sleeping patterns while on this stuff. I normally dream 3-4 dreams a night and before I was never really a dream person. I also always wake up after each dream and then have trouble falling back asleep and the dreams are so vivid and detailed. Having this many dreams usually leaves me fucked up during the day. Anyone else have this?

October 8, 2009 at 10:15 am
(157) Shami says:

Has anyone experienced unusual anger after having a few drinks while on wellbutrin?

October 11, 2009 at 1:39 pm
(158) Mal says:

This thread has been really helpful but also very scary at the same time. I just started taking WB about a week ago (300mg). I just had a baby 2 months ago and I have really wanted to have a couple of drinks, but now I’m concerned. I was wondering if anyone has ever taken it strictly for postpartum depression?

October 11, 2009 at 5:32 pm
(159) Mal says:

I also wanted to add that my postpartum is VERY severe and I’m concerned when the doc tries to take me off in 6 months that it will cause me to go into a bad deep depression again. Has anyone experienced this when stopping WB? (sorry this question isn’t really concerning the alcohol)

October 20, 2009 at 3:15 pm
(160) anna_78 says:

Spencer, i have something similar. before i was dreaming every single night, but now (with wellbutrin) even more, deeper, defferent, vivid,…. but quite good dreams. just one night when i drunk a little too much wine in the evening, i had such a nightmare like never before in my life!!! i woke up and then nightmare again… woke up again, nightmare again… it was really scary. so, 5 glasses of wine for me is the limit.

October 21, 2009 at 10:57 am
(161) Jennifer says:

I took Wellbutrin for approximately one month in 2007 for minor depression. I went to a happy hour with a friend while on the drug and had a couple glasses of wine over several hours (and ate dinner too). Apparently, I called her on my way home and she didn’t answer so left an unpleasant voicemail on her cell phone that I have no recollection of in which I was swearing and accusing her of flirting with my husband. When I “came to” I was sitting in the parking lot of 7-11 a block away from my house. I had driven for miles and made this phone call and had no recollection of it. When I got home, all hell broke lose. My friend’s husband called wanting to know why I said those things to his wife and I could not even remember making the call. I became hysterical and had suicidal thoughts. It was so incredibly scary and so unlike me. I lost a friend over this (but really in my mind if she was a true friend she would have forgave me as I was not in my right mind but that is another matter). Please do not take the chance and mix this drug with alcohol.

October 24, 2009 at 5:37 pm
(162) ken says:

me and my wife had a few drinks and she said we was intimate but I don’t remember any of it. I drank as much as I normally drink but never had taken wellbutrin w/ it before. I don’t remember it but she swares it happened.

October 26, 2009 at 8:02 pm
(163) laura says:

googled hangover/wellbutrin and was glad to see this website. thanks for all the comments – i definitely will not be drinking again on wellbutrin. when I was taking the generic version i could drink occasionally and never noticed a difference. my doctor said i needed to be on the name brand, that it is better. I’ve tried to drink twice while on it and have come to the conclusion it gives me a 3 day hangover!at least i now know why i feel so bad, it’s not just hypochondria.
i, for one, will not be drinking while taking this medication again!!!

October 27, 2009 at 3:55 pm
(164) Sunni says:

Thanks for sharing everybody! After several years of being off Zoloft I decided to start up again due to slight depression & wieght gain. In the meantime, I was told by my doctor that it is time to quit smoking. We decided to quit the Zoloft and go to Wellbutrin. I have the bottle of W, but am scared to death of the possible side effects. the risk of acting out against my loved ones is very scary. Has anyone had a good result with the W and stopping smoking? I don’t mind the thought of taking it easy with the drinks until I quit smoking, but like I said I am scared of the effects and trying to get off the W when it is time.

October 30, 2009 at 1:06 am
(165) Andrew says:

It seems like maybe I’m the exception to most of the comments, but I think that drinking with Wellbutrin is ok.

Granted, you have to drink MUCH LESS than you normally do. I normally can drink close to 9 beers without feeling incredibly drunk, but last night I barely manged 5 before I was totally smashed. I don’t know the after effects on your body (such as the liver and stuff), but apparently when taking Wellbutrin, you will reach a “drunk” state much faster than without taking Wellbutrin.

If you DO choose to take Wellbutrin and drink (I’m in college so i obviously drink), just remember that you will get drunk faster on Wellbutrin. That’s a good thing, right? Less money spent on beer! If you are in a Frat or Sorority, you should mention that you are on Wellbutrin or just refuse to drink after half your normal limit. If you don’t, it can fuck you up for days. Seriously, going through the awkward moment of telling your frat or sorority that you can’t drink that much cause you are on anti-depressants is MUCH better than suffering through the crappy feeling of having a hangover for days. I really don’t know if Wellbutrin effects your body in other negative ways (mainly your liver and kidneys) when you drink, but it definitely gets you drunk faster, so if you are taking it, don’t drink quite as much.

November 3, 2009 at 3:48 am
(166) Jan says:

My story is on the track of the extreme stories I read. I tend to drink a lot when I go out. I went to a guy’s house for the second time ever, and let’s just say the police came. I thought I was in a game and the devel was everywhere. The guy or I could have gone to jail because I was telling crazy stories about him. I thought I was seriously loosing it or he had druged me untill I read this site. I hope I never have to see him again, poor guy.

November 7, 2009 at 10:59 pm
(167) Ella says:

Simular experience to many of you all. Lower tolerance to alcohol on Wellbutrin xl. For those of you who are serious about stopping drinking AA can be a good resource. It is a free support group that is available all over the country. I am tryinf to get the courage up myself to go there. Eventhough I don’t feel like I am an alcoholic, I want to stop drinking completely. Wouldn’t it be nice to see what life is like, especially when we are on mood enhancers like Wellburrin. Good luck to you. I know I will need it.

November 10, 2009 at 7:33 pm
(168) Claire says:

So glad I found this thread! Thanks for sharing, everyone. I’ve always been a lightweight and have epic hangovers. I’ve been on Wellbutrin since I was 16 and didn’t start drinking until college, so I never realized my meds were the culprit. However, last week my dr raised the dose and I’ve been on 450 mg for a few days. Last night, I drank one and a half beers. This morning I felt like I got run over by a truck! I tried to tough it out but ended up throwing up at work. Looks like drinking on this dose is not an option for me. But… would it be a terrible idea if, maybe once a month, I skipped my meds so I could go out that night? I really love drinking and would hate to have to give it up completely. Has anyone tried this?

November 14, 2009 at 9:33 am
(169) Dave says:

Holy crap! 150mg/day, and it only took four drinks to floor me. I spent the next 12 hours dry heaving in the shower, and the next week in a haze. Avoid drinking if you’re on Wellbutrin…period!

November 14, 2009 at 4:22 pm
(170) Leila says:

Wow thanks everyone for sharing your stories. I’ve always been a happy drunk until Wellbutrin. Last night I actually slapped my gf twice!!!! That is not ok. I love her more than life and would never raise a hand on her. I accused her of things that were in my head. I trust her completely but when I drink I go into a jealous rage! This has happened every time I’ve drank. Today she packed her bags and said she can’t do it anymore. She was selling her condo and the papers were supposed to be signed this morning. I feel like the biggest ass on the planet and will never be drinking while on this drug ever again.

P.S. I blacked out and don’t remember any of this.

November 15, 2009 at 7:29 pm
(171) Gayle says:

From Greg’s posting in July:

“Doc says that you are messing with the neurotransmitters that you are trying to help with the medicine when you drink.”

I am going to write that one down and hope it will make a lasting impression.

I have read this thread previously, but always forget the dangers. Have a few glasses of wine at home without a problem and then forget the danger. Last night I had my second episode of not remembering, then passing out when I got home. Fortunately, I was with my husband. Unfortunately, thanks to technology, I used Facebook on my Blackberry to post lots of inappropriate stuff, and in about 5 minutes of time, PURCHASE a bunch of stuff. I was able to dust my trail on Facebook when I got up to vomit at 3 a.m.! But I am still embarrassed, and as another poster said, ashamed.The problem with limiting your alcohol intake, at least for me, is that after the first drink or two, theat resolve goes away. I am actually considereing trying non-alcoholic wine, just for the ritual of having a glass or two of wine. Wonder if that will work??

November 24, 2009 at 8:36 pm
(172) Lyndsey says:

I’ve been on Bupropion XL for the past three and a half weeks. I’ve taken the drug before and realized that the days after I drank I felt horribly depressed. And that is why I stopped taking the drug. Flash forward a few years. Friday night I went out and got drunk for the first time in a long time. It’s Tuesday night and I still feel like I’m in a pretty significant slump. After reading all of these posts, I’m going to quit drinking entirely, but I wonder how long it’s going to take to get back to feeling “normal.” Does anyone else have any experience with this? I called my doctor, but since it’s right before the holiday, it’s going to be awhile before she gets back to me.

November 29, 2009 at 2:26 am
(173) Lauren says:

Last night, i drank for the first time heavily on wellbutrin. i am only on 100 mg and i didnt think i drank that much, but i kept drinking because i wasnt feeling anything. when it finally hit me, i completely blacked out and ran around the house opening and shutting doors. Today, 24 hours after this, my heart is still freaking out. I had a legitimate severe panic attack while driving earlier and am going to go to the hospital in the morning because I am almost positive my heart palputations and slowing are due to the combination of wellbutrin and alcohol

December 9, 2009 at 11:54 pm
(174) Sam says:

It has been very emotional reading all these comments because I can identify with a lot of what is being said. I have been on Wellbutrin for a couple of years but never new until tonight about the effects of Wellbutrin and alcohol. I would binge occasionally when a friend would invite me out. I would blackout and not remember driving home. I would run outside in the middle of the night and find my car parked straight between the lines. And then the next morning I would get those horrible phone calls: “Do you know what you said last night?” “Do you know what you did at the bar?” I lost a lot of friends. I was overwhelmed with guilt. The things I said and did were out of character for me. I never new what caused this horrible behavior until tonight. I stopped drinking alcohol last May 14 during the last incident. I will never drink again.

December 15, 2009 at 12:00 am
(175) Bocko says:

Thanks so much for this site: I just started Vitamin W today and with the holidays coming up and my girlfriend loving wine I am sure I would have risked it in the coming weeks. It will be hard but I guess I’ll leave the cork in the wine bottle for me. See what happens just on the W. My doc said it could take up to 6 weeks to feel anything from this: 150mg SR generics. Here goes nothing. Thanks again for all your sharing, you all know way more than the pharmacist did when I picked it up today.

December 21, 2009 at 3:59 am
(176) tika says:

wow – this is eye opening. I knew it was not the greatest idea to drink while taking wellbutrin. I’m on 450mg of xl and last summer when I started the medication whenever we’d go out to drink, I’d drink a bottle of wine. Acting like a crazy lunatic, falling all over the place, rolling around on the dinner table, I had bruises all over my body all the time. I even hit on a girl in front of my boyfriend and I think I was serious. I thought I was letting loose but I definitely think the wine/wellbutrin mix played a big role in my ridiculous behavior. I never noticed that I was more depressed the next day because I’ve been extremely depressed for a long time and not sure if I would notice if it was worse :(

December 23, 2009 at 1:55 pm
(177) Jarvik says:

I’ve been on Wellbutrin for 6 months now. Started at 150mg Sr 2X day. I had been using Walmart generic for a month and felt great, changed to Walgreens (Teva) manufacturer and got completely depressed again. Moved to Brand 200mg SR 2X day, which immediately alleviated my mood. The change in manufacturer affected me badly. But was a quick drop and bounce back. After going to Brand I got better quickly and maintained that state for a few months.

I also found that I had way more energy and felt much more positive and as a result wanted to be social and go out and drink. I had a good tolerance of 4-5 vodkas before starting Wellbutrin and would be ok at that amount.

After starting Wellbutrin that dropped significantly to about 1 or 2. Then my tolerance was built up again after a few months and back to 4-5 and then upped to 6-8 and finally I’d be drinking 10-12 drinks a night. Once I started on my third drink I turned into a maniac that was unstoppable. I would buy drinks/shots for people, and party like nobody’s business. I started going to strip clubs and spending tons of money and blew through $8000 in 4 months. This was always ALWAYS and only after I started drinking. I could not be stopped by anyone. My friends my girlfriend. Even the strippers would tell me to slow down. I would have black outs and was completely out of control.

After drinking I would get into horrible fights with my girlfriend, ending up in:

a.) suicidal behavior
b.) violent threatening behavior
c.) physical violence
d.) reckless driving

Basically a walking nightmare.

I would wake up severely remorseful and the depression would be in full force for 4-6 days afterward. I had no motivation no happiness and no sense of well being.

The alcohol robbed me of everything I had gained from medication and severely affected my life negatively.

I have stopped drinking altogether and fell light hearted and well now.

I don’t know if the Wellbutrin exacerbated an alcohol problem, or if my depression was caused from alcohol abuse or If I was self medicating with alcohol for depression.

I can say this.
Alcohol + Depression = Severe Depression
Alcohol + Wellbutrin+Depression= Severe Depression/Mood Disorder/Psychotic Behavior

I love Alcohol don’t get me wrong. I just have to accept that I cannot use it any more if I want to be healthy and happy.

If you have depression cut alcohol out.
If you’re on Wellbutrin and have a history of drinking, try to stop drinking.

If you’re on Wellbutrin and have predispositions to addictions it may get out of hand. It can make you more prone to binge on pleasureful things as it regulates Dopamine re-uptake. Dopamine is the neurotransmitter that is released when you feel pleasure from things such as food, sex and drugs. It’s your brains way of rewarding you.

Alcohol lowers your inhibitions. Couple this with Wellbutrins ability to enhance pleasure can be a bad combination.

December 25, 2009 at 12:20 am
(178) Craig says:

I’ve been on Wellbutrin SR for about a year and have found that Wellbutrin and alcohol DO NOT mix! Recently, after only two rums and Sprite, I felt quite crazy – just whacked. Depressed, agitated, angry, irrational. I went to bed because I was so concerned about what I would do otherwise.

January 2, 2010 at 3:46 am
(179) Murdock says:

After taking Zoloft, I noticed that alcohol had a slight increase in potency. When I switched to Wellbutrin because of negative mental side-effects on SSRIs, I quickly found out that consuming alcohol was much more debilitating. I don’t feel different than I did when I was not taking anti-depressants, but I have an amplified effect when on the medicine. I also feel clumsier and more off-balance when sober.

January 4, 2010 at 1:17 am
(180) ZSunday says:

Despite all of these intimidating stories, I have subjected myself to the simple experiment of drinking the better half of a pint of Cutty Sark, and have been on Wellbutrin 150 SR for a month now, just starting my second bottle. While I’m fairly inebriated and feel a bit of a sharpness in my brain, I feel that my senses and dexterity are quite intact, especially since I haven’t had a drink in 2 months, so my tolerance is probably fairly low. While I am enjoying the buzz, I am apprehensive about the side effects and wary of the fated seizure effect. I am also not looking forward to the days of depression that so many others have seen fit to allude to. I promise to report back in the morning and report my disposition. Stay tuned!!!

January 4, 2010 at 3:07 pm
(181) ZSunday says:

Well, I made it. I slept well, had pleasant dreams, at some rice krispies, and have begun the day by rearranging furniture, accompanied by a showing of Nim’s Island on HBO. While I do have a slight hangover, it’s nowhere near as bad as I was anticipating, so all things considered, I feel just fine.
I will not, however, drink on a daily basis, because to be quite honest, The drunk was not all that enjoyable. The alcohol intensified the stimulating effect of the wellbutrin, and the wellbutrin actually blocked some of the buzz factor. It’s just not a pleasurable experience, but I suppose that could be a good thing…

January 5, 2010 at 4:39 am
(182) YaKnow says:

I have to say this is a side effect I never got from Welbutrin. I’ve always considered my alcohol tolerance strong and I think Welbutrin costs me maybe one or two drinks in tolerance max.

That being said, it gives me other problems.

January 5, 2010 at 6:33 am
(183) erin says:

Jarvic—-Everything that you said, I completely relate 100%. You summed up what I have been thinking for quite some time now.

January 12, 2010 at 9:56 am
(184) Scott says:

I am also very glad to find this forum. I have dealt with depression for over 15yrs now on and off. It’s a genetic family thing for me, but I never wanted to be on medication my whole life. I now realize that’s BS because i’ve self medicated w/ alcohol and marijuana ever since freshman year of college. Over the years i’ve taken Zoloft, Celexa & Cymbalta. I didn’t drink on zoloft (did smoke MJ) or cymbalta (stayed sober for a year on it after going about 5mo’s sober without it), but I did on celexa and it had a similar effect as other people are listing for WB, it even made me crave alcohol more because of how good I felt. I’m 33 now and am realizing that my depression is destroying my work and family life. I’m pretty smart and well education, so i’ve always blaimed my issues on other people not understanding me and the world being against me. But i’ve realized that my depression is causing much of it. I’m finally in the job that I enjoy and i’m F’in it up the last few months. I’ve been sober on and off for most of the last 5 years, but can’t make it more than 3-4mos w/o antidepressents (i’m assuming because I made it a year on them, but I didn’t like Cymbalta at all, it worked but I didn’t like my side effects). I’ve read all the seziure stuff too and it scared the crap out of me. I can’t not drink for more than about 4 days right now, so i’ve been waiting to start the meds. But after reading this I feel better and i’m going to start today. I’m not going to make it any other way. Blackouts are common on any of the AD’s i’ve taken when mixing alcohol. Most of us have to choose either the meds or the drinks, both will seriously mess you up. Good luck to everyone.

January 26, 2010 at 10:13 am
(185) Bill says:

ZSunday, this makes sense that it’s just not a pleasurable experience. I started taking W. last week for a myriad of reasons, one of those not being to quit smoking (I successfully quit over a year ago). My doctor asked if I have stopped taking pleasure in things I used to find enjoyable, and I mentioned smoking. I actually enjoyed smoking but not the health risks and the stink. So, he suggested W. because of its effects on the brain and the anecdotal evidence he’s gathered from his patients who are on it. Apparently, and maybe some people here could confirm this, they say that when taking W. to quit smoking, the cigarettes just don’t “do it” for you anymore. Also, there’s a bit of what I remember feeling like a nicotine buzz after first taking it in the morning.

But, and I’ve no idea how much this has to do with the fact that I drank on Friday, but Sunday morning I (and no idea what came over me; I’m really not like this) stole someone’s parking spot. Since then I’ve felt ridiculously guilty over something trivial. Anyone else notice an increase in feelings of guilt after taking W?

February 3, 2010 at 6:09 pm
(186) Randy says:

I noticed that whenever I drink now (that I am on welbutrin) I have a hard time keeping it down. I toss my cookies almost every time which leads to me drinking more to recover what I lost. And I generally get depressed. I know I am slowly killing myself and wish I could stop.

February 8, 2010 at 9:52 am
(187) A says:

I just started W this weekend, 150mg of generic. I had some wine last night and feel SO sick today. I was profusely sweating this morning and am extremely nauseous. I’m not sure if this is just really bad anxiety (which I regularly suffer from- but usually it doesn’t quite feel like this), or if it is from the alcohol mixed with W.

I guess regardless of whether it’s anxiety or ill effects of combining W and alcohol, if this is the feeling that will result, I will seriously need to reconsider my drinking habits. I am going to greatly reduce it, cut it out all together, or at least be sure not to do it when i have to function the next day. And that’s hard for me to say because I enjoy having a glass of wine here and there to relax.

I did ask my dr about the risks of alcohol and W and he mentioned the seizure thing. But he also said that in all his years of prescribing W, no one has ever reported having a seizure to him due to alcohol. Not saying that should persuade anyone one way or the other, just repeating what he told me.

February 12, 2010 at 1:22 pm
(188) Bob says:

to all you people who say “I stopped it for a while and then started again” – are your doctors approving this stopping and starting or are you doing this on your own? I have never heard of such a thing related to AD’s – I’ve been taking Paxil for 15 yrs and my doctor just added WellButrin 150 – I’m hoping it might actually start helping me feel…something positive

February 20, 2010 at 5:05 pm
(189) abl says:

My roommate started taking W two or three months ago. I told him that alcohol and the meds don’t mix many many times. I notice a marked difference in his behavior after he drinks. He also seems very impulsive. His DR. has also prescribed Xanax. Last night he was arrested for DWI/DUI. If you drink and take these meds, please talk to your DR. and please be careful.

February 21, 2010 at 5:06 am
(190) Al in Pittsburgh says:

I find Wellbutrin changes my life so much for the good, I have been on SR for a few months and drink beer from time to time. The only thing I notice is it hits me a bit faster and I do not have a comfortable night when I get home. I use to drink a lot in the past but have cut back over the years. For me I can not drink for months and then do it a few times in a month. I use to have 7 or so beers before I felt anything. Now it seems 4 or 5 do the same. I now have to call it a night at 7 to 10 while before it was 10 to 15 beers. That is the only thing I have noticed on it. I wonder how it will be on XL? This is what I used the last time I needed Wellbutrin and turns out I had to ask for the change this time and it did the trick. I do not think I drinked last time I used XL. I am a big guy now and has so much beer in the past. Anyone know what to think of this? Going to go snow on XL first. It could be the SR was out of my system when I drank. This would not be the case with XL.

March 6, 2010 at 8:46 pm
(191) tom says:

Dont mix wellbutrin and beer folks i had only three last night and now im very dizzy and having blurred vision 24 hours later fell like crap.

March 13, 2010 at 12:23 pm
(192) Sam says:

I have read most of the posts in this forum, and I guess the most important thing to take away from it is that it works differently for everybody. I’d say about 1/10 people on this forum have reported zero negative side-effects from drinking while on Wellbutrin. I’m no alcoholic, but I am a college student, and as such, drinking is a major part of my weekend. I have been taking 300mg of Wellbutrin for a little over a month now, Luckily, I have not had any different (negative or positive) experiences from drinking while on my medication.
My advice is TRY IT. Once. See what happens. Of course, take it slow, be cautious. But in case you are in that 10% minority who can drink while on AD’s, it would be a shame to completely give up drinking because other people have had displeasing experiences. If it doesn’t work and you feel like sh*t for a few days, then don’t do it again. If you feel fine, then thank god you tried, huh?

March 16, 2010 at 2:04 am
(193) Joe says:

I’m on 150mg sr twice a day for a month. I’ve been a regular drinker for about 20 years. The medication really reduces my tolerance to alcohol. Hangovers are much worse. I can get away with a couple of drinks at a time, feel I need to be really careful. This isn’t really related to the alcohol, but I had a couple of worrisome uncharacteristic anger outbursts two weeks into the wellbutrin. I tend to be really unconfrontational, and have trouble with low self esteem. I think that with my mood boosted from the drug, I felt more justified in acting out. Since I noticed this, I’ve been able to keep it in check, and there have been no more outbursts. My doctor says that the anger is probably the way my energy has come back as the depression lifts, and it should be easy to channel this in a positive direction.

March 18, 2010 at 1:40 pm
(194) Ashlee says:

I have been on lamictal for about four months. Then about two months ago the doctor put me on wellbutrin. at first it was 150 mgs a day. Then about a month ago he boosted it to 300 mgs a day. About two weeks ago i went to a party for one of my friends birthday. Usually i have a very high tolerence for drinking. But this was the first time i drank on welbutrin. Honestly it was very scary. It started with just 5 shots. Then two mixed drinks. Usually that would make me just a little tipsy. But after that last mixed drink, the last thing i remember was sitting on a couch talking to my friend’s brother. The next day i asked my friend what had happened. She told me everything. I had asked for about three or four more drinks after i blacked out, which definatly did not help the situation. It was very embarrassing, to the point that im not going to say what it was. But also i had a lot of muscle spasms. The next day i was hung over so bad, and ive never had a hangover before. It lasted all day and i barely had the energy to walk. Then for the two days after that i was still sick. I’d never felt so tired and nauseous. It was the worst experience of my life. I’ll tell you i wont be drinking for a long time.

March 26, 2010 at 4:13 pm
(195) Laura says:

I’ve been taking Wellbutrin for over a year now, but I just recently started taking it by itself. Before I was taking it with Celexa, and I’ve stopped the Celexa. Since I’ve been on antidepressants, I’ve become a complete weirdo when drunk. I used to be able to really drink people under the table, but now I get drunk really quick, say and do a bunch of really odd stuff, and generally end up blacking out. I’m really lucky that I don’t go out without my VERY understanding husband, because if not for him, I’d probably have gotten raped or killed by now. Alcohol and Wellbutrin are scary together. I, however, really like to drink on weekends. So, for now I’m just trying to cut WAY back on how many drinks I have so that I can stop feeling like such an a** the day after the blackout.

March 27, 2010 at 11:01 pm
(196) Alexandra says:

I take Wellbutrin together and Effexor together. If I drink I black out and when I do I act really aggressively and do stupid things like hitting on guys in front of my boyfriend who I am head over heels in love with. I don’t know why, I only want to be with my boyfriend and I have never been into the guy I made a pass at – I am not attracted to him. I have absolutely no idea how I could become this different person – it is like I have multiple personality disorder. It is so weird and embarrasing and I feel like a complete fool. Drunk on Wellbutrin is like being on steroids. It sucks cause so my social interaction is meeting up for a drink. Aaaahhh this really sucks, why can’t I just be a normal girl?

April 3, 2010 at 8:42 am
(197) Rjones says:

I have been taking W for the last 5 days for mild depression/smoking…150mg a day. I read the label warning against drinking alcohol and my Dr. warned me about the risk of seizures from too much alcohol. I have always enjoyed a couple of drinks especially on the weekends but vowed to reduce the amount while taking the med.

Last night at a party I had three glasses of white wine. After the third drink I noticed that I seemed extremely tired and slightly irritated. The laughter of the party goers seemed to piss me off. I am a very mild and relaxed person. Then I started experiencing a headache and I felt not buzzed but kind of “out of it.” The next morning I had a hangover and felt depressed (more than before the drug) and can barely get out of the bed.

What is the point of drinking if this is the end result. No more drinking for me I feel terrible right now.

April 3, 2010 at 4:39 pm
(198) Sophia says:

I am so glad I found this forum! I have been an off and on drinker for years. Started the wellbutrin xr 5 days ago, and this morning felt really great! About lunchtime decided to have a vodka and soda, then another. Next thing I know I am passed out cold for over an hour, and woke with a screaming headache! This from someone whose tolerance was through the roof! Bad, very bad combo.

April 4, 2010 at 7:22 am
(199) catalina says:

Thanks everyone for the helpful comments, glad I stumbled on to this thread. I just started on generic W SR on 6 days. The first two days were hell – but I’m not sure it was W causing it as much as discontinuation of Paxil (I had some semi-serious bleeding problems on the Paxil so my doc and I chose W together). But by day 3, I noticed my mood significantly improved. The night of day 4, my bf and I went out for a few hours with friends. I was afraid of the seizure side effect more than anything, so I limited myself to only a half of a beer (so about 6 oz). I’m normally a lightweight (2-4 drinks and I’m pretty tipsy), and I maybe have 2-4 drinks in an entire week (not a heavy drinker). And I will say that I certainly fell short of getting any sort of buzz – which is fine because I was feeling pretty darn happy on the W alone. Anyway – got home, went to bed, and woke up on day 5 feeling fine, took my W, but by mid-afternoon I got a headache and started to feel fairly irritable. Not back to my pre-W levels, but still noticable irritability. I thought maybe it meant that I needed to take a 2nd dose (I know many people do), but this thread has given me some hope that it was just from even the small amount I drank. This morning I’m feeling alright so far – headache is finally gone. I don’t think I’m crabby still, but no one has said/done anything to tick me off either. I’m so glad I really limited myself, I can’t imagine how bad I would have felt with even an entire 12 oz beer! So, for those of you who have had seizures with drinking…did it happen right away? I saw one comment that it was 6 days later, which has me a little spooked. But I figure it is somewhat dose dependent of both the W and alcohol. I’m only on 150 mg, once per day.

April 8, 2010 at 12:13 pm
(200) Mikey says:

Hmm guess I was lucky. I virtually never drink and went out over spring break. I’ve been on XL for about 2 months and I drank very heavily for me (9-10 drinks along with trops and a beer about 4 hours before that) and had no side effects either during or after and I’ve always been a lightweight (I feel two drinks quite a lot). Guess it’s different for everyone.

April 10, 2010 at 10:35 pm
(201) Drink_Well says:

A week ago I started taking Wellbutrin 100mg/day to help treat my ADHD. I drink 5-6 drinks every evening, and never have had any such reaction as the horror stories I just read. I mean Nothing. I am not taking it for depression however. Maybe I am a rare case perhaps, but then again; “life as usual” is hardly newsworthy.

April 19, 2010 at 6:56 am
(202) DJ says:

WOW! I have been taking Wellbutrin (generic) for almost a year now. I was taking it initially to combat the side effects of prozac, which I stopped taking. So I’ve been taking 300 mg of Wellbutrin XR alone now for awhile. Almost every time I drink I BLACK OUT. It’s scary as hell. I had THREE beers last night and I can’t remember how I got home.

I can’t believe it took me this long to figure out that it was the Bupropion (generic WB) mixing with the alcohol that was causing me to be such a raging lightweight. I’m known in some circles for falling asleep at every party we go to before things even really start. Sad. I’m getting off of this stuff…

May 22, 2011 at 1:50 am
(203) Christina says:

I’m not gonna stop drinking just for this medicine, like every other person on here… I’m in the same boat as you, buproprion, and wanna get off of it. Did you start taking something else that worked afterwards?

April 19, 2010 at 1:46 pm
(204) Diana says:

It has been interesting reading everyone’s comments. I started taking Zoloft ten years ago and switched to Welbutrin about 2 years ago. I take 400mg (a very high dose). Generally speaking I have never had a problem with alcohol. I have one drink a month on average… that means I drink about once every six months, but have five or six beers. Last Friday I had five beers at home with some friends. Everything was normal. I didn’t black out or get sick. About two hours after I stopped drinking I got a bit nauseous, but thought it was stress or a food or something. It wasn’t until Saturday night that I went into a major depressive rage spiral. I still have the self imposed welts on my arms. The worst part is not knowing why I was angry. I had to physically stop myself from breaking things or hitting people. My driving was crazy and I almost had a head on collision while going 50mph in a 30 zone. Could the time delay be because my pills are SR???

April 22, 2010 at 6:29 pm
(205) Psycho says:

I have taken generic Welbutrin For years, and I like beer. My observations have been if I take pills made by Anchen I tend to do better with alcohol. I do note that I don’t feel like I would normally feel when intoxicated, weird clear drunk. Have to drink more before coordination and speech are effected. But just like all above a killer head ache is a guarenteed consequence if I go to far.
Also watch the cafiene. Tremors are a drag. Remember we are all in this together I am pulling for ya!

April 26, 2010 at 12:07 pm
(206) DG says:

This weekend I got into a heated discussion with my brother-in-law and cried. I don’t remember the discussion, just the crying. My husband had to rescue me. In the morning he said you don’t remember do you? Nope. Then he says “again.” Welbutrin and alcohol do not mix. They make you a totally different person. Angry and mean. What I notice is that I cannot feel the alcohol like I used to. It takes a while for it to “kick in” and when it does it is too late. Passing out, forgetting the night and starting fights are the effect on me. I’m a mom and I don’t want my kids to see me on alcohol while taking welbutrin. I’m happy I read this thread. Now things make more sense.

April 28, 2010 at 6:24 pm
(207) Willie Wonka says:

For those that cant tolerate caffeine while taking wellbutrin, google Yerba Mate. Its a plant that has the same effects as coffee or tea but it does not increase your heart rate or give you the shakes.
I am very sensitive to caffeine, even before taking WB but this gives me a better effect (it does not spike like coffee) and it lasts longer.

May 10, 2010 at 10:16 am
(208) Sahuss says:

Hello everyone. Can anyone tell me if it possible that a person on 300 mg Wellbutrin who has a few drinks, can still have motor skills and be going in a severe state of depression? My nephew went out drinking with friends a week ago and is missing. He is an occasional drinker;His friend say that he seemed normal when he left that night. He was driving. The police have not been able to locate him or his car.
If alcohol blanked him out, he would not have been in a condition to drive, and the car would have been found.
Is it possible he was in a condition to drive sensibly but in a severe state of depression because of possibly having some hard drinks?

April 20, 2011 at 4:22 pm
(209) veronica says:

your post made me scroll all the way down to see what happened to your nephew. Is he ok?

May 14, 2010 at 4:31 pm
(210) kaitlyn says:

Wow. Im really glad to have found this!! Same ol story. Iíve been on WB XL for 2 weeks. I was starting to feel a lot better, not perfect, but a VAST improvement from the state I was in (Anxiety, Depression, Nightmares, Disturbing thoughts) brought on by a cortisone shot AND many years of drinking daily (to the point of a heavy buzz at least) My CRNP prescribed me WB and I feel much better but I still have had at least 2 drinks every night while taking it. POINT: I definitely DO NOT recommend drinking on this drug. The first night I went out and drank big time, it was to a work function (I know really stupid) and drank about 3 glasses of wine and completely blacked out. I donít remember ANYTHING that happened after that 3rd glass (I know I kept drinking though) My friends and co workers were telling me things that I was doing and saying and I remember none of it. I was apparently going off on people shouting like a banshee idiot. Also, I had to literally be helped to my front door by the cab driver because I couldnít walk. This rarely has happened in a good 10 years of drinking (Iím 28) And that wasnít even the worst part, The next morning, I was so depressed and anxious I felt like I was going to come out of my skin! I literally had to have someone come over to my house because I was terrified to be alone. It was AWFUL. I believe that not only does alcohol counteract the wellbutrinís effect, but I think it completely screws with your brain chemicals to the point that it makes you worse then you were in the first place by about 100Xs. My recommendation, give up the booze while on WB!!

May 15, 2010 at 5:54 pm
(211) Alhaderech says:

Sahuss: Have you found your nephew?

May 17, 2010 at 5:25 pm
(212) rachel says:

glad i searched this up… thought i was alone. after a binge episode (which i act like a complete idiot) i am severely depressed for a few days after. it is almost unbearable i also feel scared of the world and my anxiety is at its peak. i dont recommend drinking with welbutrin xl if depression is your cause for usage. 33 fem :)

May 22, 2010 at 9:20 pm
(213) Sahuss says:

No. Not a sign. The police have no clue.

May 29, 2010 at 2:18 pm
(214) Marianna says:

I started on 150 SR on generic Wellbutrin about a week ago. I hadn’t had anything alcoholic to drink until last night. I had maybe 4 or 5 shots of Jack Daniels, which will usually get me tipsy but never drunk. I didn’t even think about the effect liquor could have on me mixed with my medication. now it’s 1:15 in the afternoon of the next day and I’ve been throwing up constantly and my head is pounding.

you guys have no idea how much I wish I had found this site before last night. I’m never drinking on this medication again. I’ll stick with my MaryJane, thank you very much.

May 30, 2010 at 7:11 pm
(215) Ryan says:

Reading these posts has been a relief. I started taking Wellbutrin 3 days ago, went out last night and got completely out of control. Blacked out for at least 2 hours, lost my damn Ipod, I dont remember much of the night. Im glad I made it home ok. I have apologized to the people I went out with. If you are new to the drug be very careful when drinking.

June 2, 2010 at 12:56 pm
(216) Mike Thomas says:

strange to hear of everybodies similar distress while mixing with alcohol. I am a moderate to heavy drinker at least 5 or 6 drinks everyday and sometimes more. Was on wellbutrin for a little over a year, skipped a vouple of months and have been back on it for about two weeks. In all my time taqking this medication I have never experienced any difference while drin king alcohol. Anyone else?

June 16, 2010 at 9:28 am
(217) Jessica says:

Wow, some of these stories are really scary.

I have always had a problem with memory lapses while drinking, even if I don’t drink that much.

However, I started Wellbutrin about 2 or 3 weeks ago and had some drinks at my friend’s house. Not only did I completely black out after a couple beers and a couple glasses of wine, but I also drove home while still intoxicated– something I would never EVER do while normally intoxicated.

The only things I remember from the night before is my friend using her phone to drunk dial her boyfriend and a single traffic light. Not only that but my memory of the entire day before is hazy, not just the time during which I was drinking.

Luckily I was with my close friends so I’m pretty sure they didn’t let me do anything crazy (except drive home) and seem okay with me so I guess I didn’t verbally or physically assault them or anything. My boyfriend insists that he called me and warned me not to drink anymore, but I of course do not remember that at all.

The next day, however, on top of not being able to remember anything but those two fragments of the night I also got stuck in a deep depressive stupor and laid in bed almost the entire day staring at the wall.

I’m glad I found all of this out before going back to college, where I used to drink regularly on the weekends. I’m so glad I was with a few close friends in a safe place when I found out how alcohol affected me instead of in public at a party!

I will definitely not drink until I am off Wellbutrin. I would advise others to do the same. It’s definitely not worth blacking out and making dumb and dangerous decisions that could harm yourself or others.

This forum helped explain a lot! Thanks so much!

June 17, 2010 at 6:56 pm
(218) jabe says:

Wow, bless you all. I’ve read every word with a mixture of anxiety and comfort.

175lbs, 6′, male, 300mils SR generic vitamin W (for six months), is my drug of choose. Except for vitamin. V (vodka) of course.

For me, and as you can see, we can be very different; I’m buzzed faster on W. I’m buzzed faster on nicotine, I’m buzzed faster in spin class , Iím sexed up, Iíve lost weight and all in all happier. I think Welbrutin is a gift from god but it’s very true for me that booze counters the long term effects of ADĎs, negates the usefulness and basically prolongs depression. (He writes this consuming a very delicious and obviously bad for him, “cape-codder” (cranberry and vodka)

Much love and good luck to you all and hoping you feel the same for me, j

June 28, 2010 at 3:14 am
(219) Joan says:

Am new to ADs. Just got off Lexapro but kept the wellbutrin, only 150 dose as I am very sensitive to medications.
Today I had an emotional “trigger” event that made me feel inadequate, distrustful, etc. I had to face this person so I had a mixed drink, felt great; then another; then later 2 glasses of wine. I took a nap after dinner then awoke with the WORST anxiety. Exhausted but cannot sleep. And, as others have reported, I feel worse than ever. I am very concerned about wellbutrin side effects and want to get off. I hope it does not take more than a week or so.
I did make one important discovery about generics — they are not alike. The first I took was budeproprion and it caused restlessness, anxiety and no good results at all. The pharmacist switched to another generic without telling me. I compared the two on line and a comment blog described my bad symptoms exactly.
I am now switched to the buproprion which seems to allow a more normal day. However, with the alcohol, I have really crashed.
I want my life back. I have never felt good on ADs one day in the past 6 months. Right now, I do not want to see or interact with anyone. Maybe a trusted therapist. It’s not good.

July 1, 2010 at 6:32 pm
(220) Nina says:

I’m a 33 year old female, and I have been taking Wellbutrin 150mg SR for past year and half. Initially, I started taking WB, for smoking cessation, and ended up really liking the way WB made me feel. I just felt happy! All day long I will have a lil smile on my face.

Since I liked WB so much, I asked my Dr. to give me refills. Dr. mentioned that I might have been a little depressed, which I was. (Had just broken up w/ boyfriend of 3 years when I started taking WB. My boyfriend of 3 years was engaged to be married less than 1 month after our breakup.) Long story short, I’m not depressed anymore. I have a old flame/new boyfriend now! No time to think about the EX, yet I continue to take WB. I’m a daily drinker and have been for many, many years. I drink hard liquor and chase it w/ beer, pretty much on a dily basis. I have seen no changes in my drunkeness. Everything is the same, no super extended periods of depression the next day. No blackouts, no violence, nothing! I love it, and I love my alcohol, cigarettes, and mary jane!

May 22, 2011 at 1:45 am
(221) Christina says:

#1. is welbutrin exactly the same as buproprion? im taking buproprion but i think its the same.
#2 I wanna be able to NOT fucking blackout, and be able to drink like i used to, and actually ENJOY smoke going down my throat like i used to.. I can still smoke as much weed as I want, but do you think me taking the exact same thing as you would work? I take 300mg XL

July 7, 2010 at 2:21 pm
(222) Mark says:

Wow! Just started at generic at 150 mg right before the fourth of July weekend. Had no idea that it would put me in such a funk for so long. My research indicates that Wellbutrin causes the liver to work overtime in an effort to properly clear it. Mix that with the liver wanting to clear alcohol and you pretty much have the symptoms listed in the posts. Correct?

July 8, 2010 at 1:53 am
(223) John says:

Does anyone know if these effects are the same with ALL antidepressants or just with wellbutrin when it comes to alcohol.

July 19, 2010 at 6:44 pm
(224) Jean Claude Van Damn It says:

I am 240lbs 6’3 body builder, run yourself into the ground every day person. The depression you feel is ridiculious. It does taper away over time but it’s slow. It deactivates the wellbutrin because alcohol is a poison so it’s a priority for the liver. Meanwhile your wellbutrin abruptly stops.

October 15, 2011 at 12:53 pm
(225) Big Team Bodybuilding says:

Has the Wellbutrin affected any of your contest training? I’ve got a show coming up next May and I have noticed my appetite is blunted, which will obviously have an adverse affect on my ability to compete.

July 20, 2010 at 2:43 pm
(226) kathryn says:

I take 400/g of wellbutrin/day, and am also a regular drinker. Two or three drinks seems to be okay, but I have had several horrific experiences where I have blacked out after having gotten drunk. This has happened about three times over the last four years, but each time I acted belligerent, malicious, and borderline violent, saying and doing things I would never dream of if lucid. This is a bad combo, one which ends friendships and relationships.

July 22, 2010 at 6:31 pm
(227) Rusty says:

I am in the absolute zone when I am on the Welbutrin at parties and my tolerance to alcohol hasn’t increased or decreased but, rather, for lack of a better word, it has morphed into something far better. I never black out anymore when I drink on this medication. I am extremely social and more the life of the party then ever before. Welbutrin hasn’t really turned my life around per se, but it certainly beats taking Vyvanse- fuck that shit.

July 23, 2010 at 2:48 pm
(228) Jacob says:

Ive been on Wellbutrin SR 150MG for almost a year now, and various times when I would drink socially, I would black out and not know what the hell was goin on. Even if I hadn’t had alot to drink. Once, I blacked out and became pretty psychotic and went off on one of my friends. Don’t mix the 2 drugs; only in moderation.

July 26, 2010 at 11:05 am
(229) Scott says:

I had the same sort of experiences a few times. I have been taking 150 for about 4 months, but everytime (like 5 times) that i drink more than a few beers I go crazy and barely remember anything. I turn very mean towards everyone and just wonder off by myself. The next day I wake up wondering and being scared of what I have done the night before.

Can you just stop taking welbutrin a few days before you know your going to drink a lot???

July 29, 2010 at 12:02 am
(230) Desire says:

I have been on wellbutrin for clinical depression for 3 weeks now. 150mg. I only drink once a week and usually have a single drink when I do. Last night I blew through 60 dollars. How did that happen? I couldn’t tell you, all I know is I have never drank more than 10 dollars worth of alcohol in a bar, ever! I’m sore all over, covered in bruises and slept for about 18 hours today. I’m done with the drinking. Thats the end of that!

August 2, 2010 at 4:20 pm
(231) mcc says:

don’t get this forum… people that are confused because they drink too much and are on AD meds that don’t interact well with alcohol? wow, who would have known….

August 3, 2010 at 2:21 am
(232) enigma says:

Partially agreeing with mcc. Most of you don’t realise that you’re simply experiencing the normal effects of alcohol. I’ll provide you with some honest proof. Within the past two hours, I’ve consumed a pint of brandy. I’m also taking 150 mg of Buproprion/day. I can still walk, talk and type just as well as I could when I drank that much booze without Buproprion.

In my opinion, alcohol+Wellbutrin=0. There’s no intensified effect. When you drink, you get drunk. The fact that you’re on a pill doesn’t change that. If it were an SSRI, maybe, yes…but Buproprion doesn’t do that. However, I will admit this; you might feel a bit down(er) in the morning than if you had stayed sober. But it’s hard to say since the typical hangover usually includes depression.

August 19, 2010 at 9:08 am
(233) vilerick says:

I have read almost all the comments that have been posted on this website and I don’t see how anyone has not reported any deaths from the wellbutrin/alcohol combination. I am a 49 year old female and have been taking wellbutrin for years. First of all, I have to say that it works very well for depression, has hardly any side effects, and doesn’t cause a loss of sexual desire for me at all. However, from my experience with this drug and alcohol THIS IS A VERY UNPREDICTABLE AND DANGEROUS COMBINATION!

When I first stated to take wellbutrin (150 mg/day) I noticed right away that drinking just didn’t feel the same any more and I seemed to get drunk faster and with smaller amounts of alcohol than ususal. I just figured it was because I was getting older and have been drinking off and on (oftentimes heavily) since I am a teenager. I started taking wellbutrin for depression but I wanted to try to quit smoking so my doctor increased the dose to 150 mg 2x/day. I knew that if I quit smoking I would also have to quit drinking and so I did quit drinking for about 2 months. Well, I was having a very rough day so I got myself a medium White Russian daiquiri (I had been accustomed to drinking 2 large – these are made very strong from a little shop by my house with their own receipe). I had only drank about half when I realized I was really drunk and felt sick. I lay down only to start throwing up and my son tells me I had a seizure. (I have only had one other seizure in my life when I was much younger.) Also I was very sick that night and all the next day! I couldn’t believe that I had gotten that drunk and that sick on so little alcohol!

For money reasons, I went back to my usual dose once a day, blew the seizure incident off, and still drank on occasion. But I still noticed that I seemed to feel drunk almost immediatly when drinking, my speech would get slurred right away, and I was doing and saying lots of off the wall things.

A month ago, I went back to the twice a day dose and am trying to quit smoking again. However, I had two White Russian mixed drinks while shooting pool in a tounament 2 weeks ago and feel like I almost died that night. I got so drunk so fast! I was embarassed and felt sick so I went outside and sat in my car. Well it wasn’t long before I threw up and realized I was really wasted. There was no way I could walk, let alone drive, and I couldn’t even use my cell phone! All I could do was sit there in my car and cry. I felt just awful! I kept trying to call my husband but I couldn’t see the numbers on the phone and I just cried and cried and asked God to please help me because there was nothing I could do about anything at this point.

I don’t remember anything after that! It seems I did call my husband (my phone did not show that I had called him however!) and he came get me and brought me home. I don’t remember him coming to get me, the ride home, or walking in the house (he said I did but I don’t remember any of it). I thank God that I am alive and I don’t know how I did not die that night! My husband said he almost took me to the hospital because it looked like I had alcohol poisoning. It scared the heck out of me and I haven’t had a drink since!

From all the comments posted, I have gathered that most of you are young college students. I am afraid for all of you out there because I know how much alcohol is a part of the social scene for you all. PLEASE PASS THE WORD ON TO OTHERS ABOUT THE DANGER OF WELLBUTRIN AND ALCOHOL !!!!!!! YOU NEVER KNOW WHAT IT WILL DO TO YOU AND WHEN!!!!!!!

August 21, 2010 at 11:24 am
(234) Clary says:

I drink very little but noticed immediately after starting wellbutrin that something was different. My twice weekly ONE Smirnoffs wild grape seemed to give me more of a buzz.
This was on only 100 mg. Then one night I had a glass of red wine & was doubled over in pain for HOURS- not throwing up just the worst stomach pain I’ve ever had not being in labor! I suppose something else could have caused it. I rarely ever drink wine so who knows? Also frequently if I had one mixed drink I was getting VERY nauseous-strange! For this reason I seldom had two. Less than a wk ago my dosage was increased to 150 mg. Last night I had two mixed drinks w vodka- each was around 12 ounces w maybe a shot & a half each & I became about as ill as I’ve ever been in my life- I honestly thought about going to the hospital. I was throwing up uncontrollably & the dizziness was the worst I’ve ever experienced in my life. It took me 2 1/2 hrs to be able to walk at all & I threw up for a total of 7 1/2 hrs.
IF I EVER have another drink while on wellbutrin if will not be more than one!

August 31, 2010 at 9:10 am
(235) missy j says:

I can now drink like a fish……without a bad hangover but I don’t get drunk. Takes a whole bottle of rum to feel anything. At first I thought great! But I’m worried about my poor liver. If I skip my 150 mg night dose, seems like I can I can catch a buzz easyer. Always take my 150 morning pill. Been on this for 3 weeks and feel no different, but my husband seems to like me again so maybe it is working. Still want to smoke….hope that changes!! Kinda sucks that I have to do shots….lots of shot to get a buzz. Don’t enjoy having to drink SO much. Better than getting sick and mean I guess. At least I can have a few beers if I want, just no more buzz unless I drink a whole bottle of hard alcohol….yick.

September 6, 2010 at 6:28 pm
(236) shelly says:

I am so happy I found this today. I have been dealing with depression/anxiety D.O. for half my life at least. I’m currently on Wellbutrin XL 300mg divided dose for the last 3 weeks. I drank a big bottle of wine Saturday at a party, felt nothing but depressed, dispondant, and miserable. Then I threw up. The next day I felt ok, had some more wine (yes I’m a dumb ass) and today I feel so nauseous, my stomach is cramping and I am one DSM IV symptom away from suicidal. I feel so miserable and down today that I’m scared. After reading this I plan on drinking lots of fluids and trying to get a good nights sleep. Tomorrow will be a new day and hopefully better. To anyone reading this SKIP THE ALCOHOL!!!!! The next day sadness, anger, guilt and depressions are so not worth it.

September 17, 2010 at 4:21 pm
(237) Tyler says:

I guess everybody reacts differently to wellbutrin. I hadn’t been feeling myself, and have had low energy, loss of apetite, depressed. I just started taking 150mg of wellbutrin xl 1x a day a little over a week ago, the first day I took it I felt a difference in energy and focus. I have gotten drunk a couple times since then, the first time, I went out to the bars and probably had like 10 or 11 drinks (shots and beers) over 5 hours (I am 175lbs), I did have 1/2 of an energy drink beforehand too tho, probably didn’t need that. Anyway as the night progressed I felt more awake, energized and lively, very fun. Never violent or anxious or depressed or anything. Although I definitely did not feel drunk, more like a strong buzz, it only felt like I drank 1/3 as much. I tried going to sleep though, and hardly slept, maybe got 2 hours of sleep… just that 1/2 energy drink with wellbutrin pepped me up too much, the alcohol probably didn’t help with sleeping either. The 2nd time I got drunk I drank 6 drinks, I didn’t have any energy drinks, i felt a little more drunk because i wasn’t as active as the bar night and no Monster, but I slept fine.

On both mornings after, hardly any hangover!

Be careful with this drug though, take it easy and see how your body reacts to it with different things like alcohol. I had 2 mugs of coffee before work one morning, and for the first 2-3 hours I felt so hyper it was very uncomfortable, felt a little dizzy and was sweating. be careful with caffiene.

I am doing better as of day 9 today, feeling better about life because i have energy to do things that I didn’t have the drive to do before.

September 26, 2010 at 1:22 am
(238) Allie says:

So. I’ve read through all of these, and I’m scared, especially of potentially self-prophecizing (yes, I just made up that word..)

I’m supposed to drink with my boyfriend and his sister and one of our managers tomorrow.. so tonight I’m going to have a bit of a test run, having some drinks with another friend. We are drinking at a public park, so it’s obviously going to be mixed by myself. I’ll be sure to keep it weak. but we’ll see how it goes! I have no worries about keeping sane, or blacking out. I just don’t want a seizure..

PS this is my third day, still at a 150mg dose of W XL.

September 26, 2010 at 3:59 am
(239) Amber says:

NEVER OVER DRINK ON WELLBUTRIN. I’ve been taking wellbutrin for about 3 months. It was having great effect and I kept on drinking socially with no issues. The past week I’ve been drinking more than normal and I started feeling more depressed than ussual.

Last night I was talking to some friends at 12am in a bar and suddenly I woke up in the back seat of my car in a parking lot at 4am. I have absolutely no idea how I got there and this has never happened to me in the past. Aparently I told one of them that I wanted to fuck him repeatedly and he hasn’t talked to me since. I have absolutely no memory of that happening.

DON’T drink more than a couple of beers with this medicine. Not only does depression get worse but you can pass out like me and have absolutely no idea what happend.

September 26, 2010 at 6:28 pm
(240) Allie says:

So, I had about two and a half-three ounces of alchol last night, in the span of two hours. Nothing really felt different, but I was mostly testing the waters and not pushing it much. At any rate, I’m happy I didn’t even have the slightest hangover! I felt really emotionally volatile once, but that was just from something I would have experienced nonetheless, and it went away when I distracted myself.

September 29, 2010 at 3:29 pm
(241) Angela says:

My biggest concern is the MEMORY LOSS. I have been on 150 for almost 2 years. I am a social drinker on the weekend. I noticed a higher sensitivity to aclohol, so I was careful not to drink more than 3-4 drinks. Lately, I have been having severe memory loss. I go through the night enoying myself, and the next day see photos and have no recollection, then friends say, dont you r remember you did this or that. Nothing – I can’t recall anything. No negative experiences, just can’t remember. My dosage hasn’t changed, but I am noticing lately I am having problems remember even while I am not drinking. Has anyone experienced this??

September 30, 2010 at 4:35 am
(242) Leah says:

Wow, I’m really glad I found this thread. I was surprised when I saw the alcohol warning on the bottle because my doctor or the pharmacist didn’t warn me in the slightest about drinking. I even read the medical info and all I could find was it makes you “more buzzed.” (btw I’m on 300mg a day of bupropion for depression/ADD and have been on it for 2 weeks).
So, I went to a bar last night and decided to have a beer to test if it would make me more tipsy than usual (I’m a borderline lightweight). I drank 3/4 of the glass when I started feeling the effects. I felt more DRUGGED than buzzed. A few minutes after that I started talking slurred the way I do if I’ve had 4 shots. I also had slightly blurry vision and a little tunnel vision. After that I became very nauseous and it’s lasted until the next day, although less. I threw up in my mouth manged to keep it down since we were in a very crowded area. Luckily I had the sense to not get another beer. If it weren’t for the nausea I might have…and judging by what I’ve read I definitely could’ve blacked out (I black out easily anyway). I was with my boyfriend so I told him how I felt. We stayed there another hour until my “drugged” feelings subsided and I felt better after chewing gum. I drove home that night and was fine doing so since it had worn off.
After reading the replies I’m definitely for putting the bottle down. I was a light/moderate drinker before (4-6 drinks/week) but I have to say I’m bummed that I have to. I really like the bupropion so far, *but* I’m 22 & a college student and my bf and friends drink socially pretty often. I also like having wine with dinner occasionally.
I’m worried that me not drinking will have a negative effect of my social life. I’ve also thought about just drinking O’Doul’s or trying non-alcoholic wines to satiate any cravings, but it doesn’t seem the same. I feel like I’m an outcast now. I just wished that I was warned so I could have one last hurrah before starting bupropion. :(

October 10, 2010 at 8:47 pm
(243) Johan says:

I took Wellbutrin for both bipolar disorder and as part of a ‘stop smoking plan’. My roomate & I were both taking it and supporting each other’s plan to stop smoking cigarettes. Well after any potential ‘nicotine fits’(a couple of months), we both started noticing that minor irritations at work, etc. were causing us to overreact. One weekend night, during our normal light-drinking(alcohol/beer)and playing pool outing, I total went crazy and I mean psychotic blackout crazy. I freaked out verbally abusing my girlfriend, broke up with her, then went home an was going to shoot myself in the head. Either my roomate or my ‘by then ex-girlfriend’ called the police. Luckily I was having borderline seizures(tremors/muscle spasms) and kept jamming the first round every time I racked the slide of the gun. The police took me to a psych ward, where I spent over a week getting evaluated. I don’t remember much, but I was severely traumatized by the whole experience and the significant repercussions/consequences. I ruined a previously healthy relationship with my GF and my roomate/friend has been terrified of me ever since. He said just my ‘glare’ at him made him feel as if my hands were actually on his neck/throat choking him(although we were many feet away from each other during the ‘police episode’, according to him. I feel it very safe to assume that I was beyond simply ‘intense’ or psychotic. Just a warning to those who have psych issues. Don’t mix alcohol with ANY mood stabilizers or antidepressants, especially Wellbutrin which seems to exacerbate the effects of alcohol to an extremely unpredictable level.

November 9, 2010 at 4:11 pm
(244) dani says:

Im on wellbutrin and not drinking any alcohol. But with the holidays coming up as well as my birthday I would like to drink for these special occasions. Does anyone recommend I stop taking the wellbutrin for a few days before or just keep taking it and deal with the killer hangover the next day? Just wondering if anyone has any experience in regards to a similar situation.

November 11, 2010 at 2:00 pm
(245) Elizabeth says:

i weigh 120 so i am i pretty small person and i usually can drink guys under the table i started welbutrin and kept drinking the usual amount i drink i usually can drink about 10 shots and continue with beer…the next day my depression is unbearable. i just thought it was me going crazy but now i realize i drink wayyy too much and i blacked out every single time i drink so i guess now that i realize how others are affected by the little amounts of alcohol my drinking is going to have to stop..

November 16, 2010 at 2:09 pm
(246) Lindsey says:

Yesterday my Doc wrote me a script for generic Wellbutrin…XL 150 so I am new to this AD.
I have been on Celexa for anxiety/depression for at least 2 years. During that time I continued to drink and had frequent blackouts, usually in my kitchen/bar at night where I would raid the frig after 2 bottles of wine, or a half a fifth, or 6-8 beers. The next morning I had little or no recall of what or how much I had eaten or what I had said. I rarely had hangovers but my motivation, will, and desire to change, exercise, or succeed was stifled beyond belief. I never associated the Celexa with the blackouts but I sure as heck woke up to the fact that 20 additional pounds gave me a reason to be depressed now!
Sooo, we enter the land of Wellbutrin XL150.
My first day, I popped one in the car leaving the
pharmacy then came home, got on the computer and found these posts, OH MY GOD!!! Had I read all this prior, I would never have filled that script and saved my $120.00. I have felt slightly sick all day and night. Probably should not have taken the first dose yesterday since I drank about half a fifth the night before the Doc saw me in her office.
Although I love to drink, I will be brutally honest when I say this–I cant stop at one drink. However, the above posts have literally scared the daylights out of me. I will give the XL150 a 30 day trial run with NO alcohol and see how I feel. It seems to me that sobriaty enhances the lives it touches.
I have never been in rehab so the next 30 days should be interesting as I get to know a sober, skinnier me in my own form of self-imposed rehab. Years ago I attended AA and heard people saying they were on Wellbutrin, and would become voilently ill if they drank. I failed to remember that tidbit of valuable information until just now…go figure. Thanks for letting me contribute.

November 17, 2010 at 10:48 pm
(247) christine says:

i’m a part of the group that it now takes more for me to feel drunk. i’m on 100mg SR. i can say that when my buspar was upped, i think too much whiskey caused me to sleepwalk.

November 23, 2010 at 10:16 am
(248) nightmare says:

This is the most nightmarish combination on planet earth. now i know why my friend hanged himself in high school. i started taking it a few months ago – since then, I’ve blacked out several times, turned INTO THE HULK and went completely berserk other times – TOTALLY out of my mind, shenanigans were out of control… mischief, MAYHEM….

after a few drinks, TOTAL chaos + turmoil + havoc + chemical induced lunacy + neurotic… AND I’M ONLY ON 150mg!!

i can’t IMAGINE what you people on double/triple the dosage had to go through. this medication HAS TO BE more dangerous then CRACK – it should be outlawed in all 194 or 195 countries across the globe.

i’m almost 30 so i can’t fathom any college kids on the drug and drinking that Four Loko madness, it’s got to be utter madness.

Wellbutrin should be a CLASS A controlled substance up with Heroin, Cocaine, Methadone, LSD, Ecstacy, etc.

December 2, 2010 at 4:53 am
(249) Giovanna says:

I just started taking Wellbutrin 150mgs about 6 weeks ago. I am a 5’6 ,120 pound female with an extremely high tolerance to alcohol. On the 2nd week of taking wellbutrin I decided to order the same cocktail i always drink Absolute Vodka and water. After finishing the 1st drink i felt really buzzed and then the 2nd drink i was already slurring.This is Not Normal for me. I didn’t even remember driving home. {and thats not good} I woke up the next day with a pounding headache, extremely dizzy and lightheaded which never happens to me even with downing 10 drinks. I really had no idea what happened to me that night. The next day i started thinking maybe somebody put something in my drink.But then a week later I had my usual drink and was buzzed again after the 1st drink and super drunk after the 2nd and woke up with the same pounding headache dizziness etc.which took 2 days to recover from so then i put 2 and 2 together{and with the help of this website of course}and figured out that wellbutrin and alchohol DO NOT MIX. I Don’t want to stay on Wellbutrin if it has such a powerful negative effect with alcohol like it does.It makes me wonder whats really going on in that pill and what long- term mental or physical problems that could arise later down the road.I am a health freak and wellbutrin is the only man made substance i am on. So I already feel very guilty for being on it. Does anyone know a natural or Holistic alternative to any Antidepressants? Thanks so much for everyones stories ,they have helped tremendously!

December 2, 2010 at 5:00 am
(250) Giovanna says:

Nick …..Yes I have experienced everything you have felt after drinking on Wellbutrin. Are you going to keep taking the wellbutrin?

December 5, 2010 at 1:31 pm
(251) Robert says:

Hello everyone. I take Wellbutrin XL for quiitng smoking and mild despression and anxiety caused by quitting smoking. It took 10 days for it to actually start working, 150 mg for 7 does and then 300 mg for the next 5+ weeks. I am in week 2 of taking the 300 mg and I just want to say, do not drink more than 2 beers at the most while on this drug. I made the mistake of drinking 2 8% hard lemonades, followed by 2 generous shots of both Jack Daniels and cheap vodka. The next morning I woke up with a really bad hangover and took my 300 mg dose then went back to bed. I woke up 2 hours later and and felt not only the hangover effects doubled in strength, but every bad side effect of Wellbutrin was intensified as well. The worst part was the extreme dizziness when closing my eyes. I would get these contstant sensations of falling. I had anxiety attacks and feelings of dread. I had no appetite and anything I ate I threw up shortly. I was able to manage a bowl of cerial and a bowl of chicken noodle soup for the entire day. I also had severe muscle twitching (legs and whole body at times) and sometimes I experieinced shortness of breath. It also made my heart palpitations twice as strong (I got that right after I quit smoking for some reason). Lastly, any amount of exertion would cause my pulse to race and I would see dancing spots in the peripheral of my vision. I spent the whole day in bed with the covers drawn while wearing a night mask. I experienced all of this until 2 am when I was finally able to sleep for an hour.

I called the poision control center around 11:30 am the following morning and they what I experienced was the hangover and Wellbutrin side effects intensified. I also asked him if I should continue my daily dose since I was very hesitent to do so and he said to do it because it may cause more complications if I abrubtly stop taking it. I just took it and am hoping I do not have a repeat of yesterday.

Alcohol and Wellbutrin are not good friends!

December 9, 2010 at 12:38 pm
(252) Kali says:

I guess I am one of the few here, I have been on wellbutrin for 6 years, 300 MG split dose, and have no issues drinking. I can have a couple glasses of wine and be fine. I drink socially and haven’t had any issues with getting over drunk, psychotic episodes etc. Just the same as before. Everyone’s body will react different and metabolize any drug differently, so while this may be an issue for some it won’t be for all. Just use caution when mixing alcohol and ANY meds!

December 9, 2010 at 6:37 pm
(253) Carter says:

I am taking bupropion (wellbutrin) for smoking cessation. On vacation, I had several drinks and basically, flipped out. Odd, rude, very out of character behaviour – no violence but very disturbing. I didn’t realize it was happening and only put the pieces together the next day. I plan to avoid alcohol for the remainder of my time with wellbutrin. On a positive note, after 3 weeks on 150mg/day, I have little craving for cigarettes.

December 16, 2010 at 3:00 pm
(254) Brian says:

I’ve been on Wellbutrin SR for two weeks now. I had been avoiding alcohol since starting, but decided to get some beer last night. Got drunk with a fraction the amount. Today = terrible anxiety, impending doom, urge to flea, but nowhere to run. It’s gotta be the Alc from last night because up until today I’d felt a steady ramp-up in my mood. Now I feel all twitchy, jumpy, guilty (without cause) and nervous. Bad combo!

December 18, 2010 at 12:40 am
(255) Jon says:

I’m not sure what to make if this thread. I used to take welbutrin as a teenager (now 28). I recently started taking it again to kinda level me out. I’ve been on it for about 2 wks now and I can def tell it’s helping in my day to day life. I’m taking 150mg 2x a day. The only reason I looked up any interaction with alcohol was because this morning I happened to pay more attention to the label and noticed a rather large warning that said not to drink. Not sure how I missed it over the past 2 wks. Also, my dr didn’t mention anything to me about not drinking. That may be better left for another forum. Anyway, my point is that I haven’t had any of the symptoms you guys have discussed so far, and I guess I would be considered to be a moderate drinker (?). Maybe I’m the exception to the rule. I may have 3 or 4 beers one week, but then have 25 to 30 another week. I’m not an alcoholic by any stretch, just an enthusiastic social drinker. I’m currently 4-16oz beers in and I feel a slight buzz. I got pretty sh** hammered at the beginning of the week and never had any serious boughts of depression, no fits of rage or loss of memory; just the usual hangover. I’m not critisizing or disparaging anyone, I just thought I’d put my personal experience out there. Good luck to everyone out there. I wish you all the best.

December 19, 2010 at 4:11 am
(256) Josh says:

NEVER I repeat NEVER drink on this medication.

I went to the bar with some friends the other night, after a few drinks I blacked out. There’s pictures of me with people that I don’t remember taking, I don’t remember leaving the bar or making it home. My parents had said my two friends drove me home and helped me walk inside the house because I was so drunk. I also had vomit all over my clothing, which must’ve happened either at the bar or in my friends car. Once home, I went into a violent rage and threatened to punch my dad, I began punching walls, made my way downstairs to drink out of my rum bottle while I was already black out drunk. I woke up the next day not remembering a single thing.. the last thing I remember from that night was me leaving my house. This has NEVER happened to me before while drinking, and my tolerance for alcohol is very high. It has left me with extreme guilt and embarrassment, and am left feeling more depressed 3 days later than I was before that night occurred. PLEASE if you are taking Wellbutrin.. do not drink. I was a very heavy drinker, and this experience has left me never wanting another drink again.

December 28, 2010 at 4:45 pm
(257) Mandy says:

This forum has been extremely helpful. Like many people here, I had no idea that alcohol and Wellbutrin were such a crazy mix.
I take 300 WB and 10mg cipralex. It seems to work well, but when I drink, I go crazy. The word used here often – unstoppable – is perfect. First of all, I seem to be able to drink a lot more than I normally do, and like many here, don’t feel the effects like I used to. And for the first time, I experience blackouts – large parts of the evening that I don’t remember.
Although I never get violent, and never hurt anyone, I become extremely sexually promiscuous and get myself into crazy situations – and I’m impulsive and driven to do so.

Does anyone else experience that – sexually reckless behaviour?
I am definitely going to lay off the alcohol, although it will be difficult for social reasons. I usually lead a very busy, professional life, with dinner parties and going to restaurants a lot. Not having wine will be difficult, but I’d much rather be sane, and safe, and not suffer crazy guilt or waking up in strange places.
Thanks to everyone who has posted here.

August 29, 2011 at 12:14 pm
(258) AP says:

I know exactly what you are talking about. It’s almost as if you are watching yourself do things that you never would otherwise do because you’ve lost all inhibition.

September 19, 2011 at 1:25 pm
(259) Vanessa says:

I also have experienced uncharacteristic sexual promiscuity and recklessness. It is very scary, very unnerving and puts me into a panic the next day.

December 28, 2010 at 10:28 pm
(260) mary says:

Very glad to have found this forum.
I have been on Wellbutrin a few years 200 SR daily. Whenever I attempt to drink wine I am affected terribly. For days (usually 1 to 3) I feel terribly ill, vomiting ,foggy & very depressed. I cannot personally drinki or consume lots of sugar now.
Thanks all,take care

December 31, 2010 at 1:37 pm
(261) D says:

I have been taking 300 mg of Wellbutrin XL for over a year and have had no interaction issues with alcohol. I am only a social drinker (1 time a week maybe) and may have up to 4 drinks with no ill effects – No depressive episodes as described above. I think that it really depends on each persons tolerance.

December 31, 2010 at 4:36 pm
(262) Justin says:

Hello all,

I am also very glad to have found this forum. It has many peoples’ experiences to compare, etc. The thing is, a few weeks ago my eyes would want to go to double vision and I was baffled. I didn’t even think of it being the Wellbutrin SR! I guess it must be! I am on 150 2 x a day. I’m also on 3 mg of xanax daily and I don’t know if that helps or makes the side effects worse. I also noticed a speedy heart rate once in a while; the panic attack type, but not THAT severe. It’s New Years Eve and I don’t know what to do!!! This is beat. :-/ Anyway, Happy New Year to all and I hope everyone has a fun and safe evening.


January 5, 2011 at 12:00 am
(263) jesse says:

I am an identical twin and have seen my brother in many situations. The story is this… We came from humble beginings. My father was number 14 and all his family has had anxiety issues. My father had big dreams and made them come true. After finishing our MBA’s together we opened a restaurant and worked with my father’s plan. It became very successful and twenty year later, I have a wife and two children and he is single. He has always drank, but after my father died and many years of waiting tables, he felt empty. He drank more. He found a doctor who gave him xanax and wellbutrin. He told the doctor that he quit drinking, but hadn’t. Today I find myself with a person I do not recognize after 45 years. He will do and say things at night, and the next morning he doesn’t even recall. I try to tell him exercise and faith but after three years nothing is getting to him. This can really tear a family apart. Mixing these are bad bad bad. Without self control and or help from family and friends, something bad will happen. I would like to believe after one bad experience with this lethal cocktail one would change but it hasn’t. Don’t know what to do! Wish dad was still here…

January 10, 2011 at 8:21 pm
(264) Rachel says:

I am very glad i just came about this site. I have been on wellbutrin for almost 2 years and it has helped immensely. One of the primary reasons i was put on it was for some anxiety and seasonal affective d/o in which i would get very unmotivated during the winter months. I was always a social drinker and have a big social group so there is always something going on and a lot of the time in involves alcohol. Since i started taking wellbutrin i noticed that i can drink more at one time then before i used to however i do have frequent memory loss and the most severe hangovers i have ever experienced, including being depressed for about 3 days after. Then by the time the weekend came i would do the same thing again. Since finishing my grad classes which were on saturdays i drink more because i would go to happy hour fridays then out sat night in which i couldnt before because i had class sat mornings. If i did drink i would never make it to class. My hangovers consist of puking, severe headaches and stomach pain, dizziness, inability to concentrate, anxiety and then depression. Like i said that lasted for a few days. After doing this cycle for a few months i have decided that drinking is no longer worth it. As many of you said i can have a glass of wine with dinner or whatever but thats it. It got to the point where i wouldn’t even go to work on monday because i was so sick, sometimes still tuesday! I thought it was all in my head or maybe i was depressed and then i realized it was from the effects of alcohol and wellbutrin.

January 11, 2011 at 12:47 am
(265) luke says:

same story as everyone else. I’ve been on W for a week and have noticed a huge drop in my tolerance. I also feel very anxious and depressed after just a few beers. This is not normal for me at all. Have always enjoyed binge drinking, but now I think i am going to give it up completely.

January 24, 2011 at 2:25 pm
(266) Annette says:

Been taking WBXL 150mg daily for about 2 months. My friend and I went out for dinner and I had 1 margarita.
The next day, I was sooo depressed, I cried and cried.
I have not cried like that for a while. After reading everyone’s comments, now I understand why not to drink
on W. I hate it, but I have to give up alcohol all together,
it’s just not worth it.

January 27, 2011 at 9:26 pm
(267) Alexis says:

I was put on Wellbutrin a few weeks ago for smoking cessation (though I was also on it, among other antidepressants, in high school for the usual reasons. I’m 23 now and have been maintaining my own mental health for about four years with moderate success). I’m usually quite a heavy drinker, and I handle it well. Last week I came home on Friday night, late as usual, and according to my roommates acted very bizarrely in ways that I have absolutely zero recollection of (blackouts are extremely unusual for me).

A few days ago, I was drunk again, and I got very agitated and started bawling and decided that I should kill myself. I took what was left of my bottle of Wellbutrin, totaling about 4,000mg. Even at my most depressed, I have never attempted suicide in my life. I spent the next 12 hours vomiting all over my room without knowing that I was in my room – I was hallucinating and delusional and extremely agitated, I felt like my heart was beating out of my chest and I was afraid that I might have a seizure. Luckily I have some experience with bad LSD trips from high school, and this was similar enough to one of those that I managed to maintain some grip on reality and keep some objective tabs on my physical state. I didn’t call an ambulance because I don’t have insurance. For 24 more hours I was nauseous and weak, like I had the flu. Now I feel fine, at least in body.

I’ve stopped taking Wellbutrin. I’m also going to refrain from drinking for another week or so, until I can be sure that the drugs have totally cleared from my system. Mentally, I now feel depressed and confused, more so than I have for years. I’m also very, very embarrassed because my roommates (I have many) know what happened I’ve unduly frightened both them and myself. I can’t believe I would do something so selfish and I’m full of shame.

January 30, 2011 at 6:08 pm
(268) Melissa says:

I’ve been on Wellbutrin for 2 weeks now. I thought the really bad stomach nausea was from an antibiotic I am on, guess not. I’ve been drinking my normal 4-5 drinks when I go out and suffering hugely late at night and the next day with severe headache and horrible nausea. Clearly I cant drink while taking this medication. No bizarre behavior, no blackouts… Just feel really shitty. My quit day for smoking is 5 days away… Guess I will quit drinking until Im well over smoking… Its all good…

February 3, 2011 at 3:34 pm
(269) Luke says:

I’ve been on 300 of WB for 8 weeks. I find I can now, at most, handle one drink (of whatever variety), but by handle I mean tolerate the nausea and cloudy-mindedness that ensues. It isn’t enjoyable. Historically, my M.O. has been moderate-heavy drinking, and frankly, I’ve always enjoyed drinking, buzz-wise and as a social lubricant. So, in sum, I have to choose: WB or alcohol. As I have had no positive effects (in treating my depression) from the WB, it is taking a lot of self-control not to quit my meds so I can enjoy ye olde drink again. I thought that by 8 weeks the full effects should have kicked in, but what do I know?

But I don’t have to tell you that =) I know all of you reading this understand these battles far, far too well. Not to be sappy or anything, but I appreciate the comraderie of this board; comforting to know I’m not alone.


May 22, 2011 at 2:00 am
(270) Christina says:

so how’d it work out? ive been on it 6 weeks, blacked out and drove my car into a crime scene surrounded by cop cars b/c i thought they were trying to pull me over haha. sat there until one of them walked up to me. luckily they didnt give me a dui. Anyways, did you choose WB or alky? or did you change antidepressants? I’m not feeling any better from the WB and I’m planning on getting off it.

February 10, 2011 at 1:45 pm
(271) Jennifer says:

Isn’t is amazing the way Wellbutrin can affect everyone differently? I’ve been on it for 2 1/2 yrs, am a 31 yr old female. I took Lexapro for a couple of years, then Zoloft. They both helped greatly with my anxiety, but seemed to make me more depressed. I gained nearly 30 lbs, though I didn’t seem to be eating differerntly. I was so sluggish and tired all the time. I would say Wellbutrin has changed my life, in good and bad ways. I dropped the weight, have far more energy, and overall am clear headed and more productive. (it’s also helped with my ADHD). But wow….if I ‘overdrink’….I am an actual monster. I say and do the most horrific, evil things….namely to my boyfriend, who could very well be a saint. I often black out for minutes at a time, and I usually go from pleasant and fun and normal to demonic at the flip of a switch. I say things that are so cruel, I can’t believe they would come out of my mouth. The next day…I can’t even function. I cry, and super depressed, and have suicidal thoughts. I’ve determined this ONLY happens when drinking is involved. I love my wine…the thought of never drinking again upsets me (borderline alcoholic?) But in order to save my sanity and my relationships, I will have to change. I do think Wellbutrin has helped me greatly- And the validation this board has provided is such a relief.

February 12, 2011 at 6:45 am
(272) dontwannatwitchaftertwodrinks says:

I have also been on Wellbutrin XL 150mg for almost 2 months, and have had some noticeable side effects when drinking a small amount of alcohol. I used to be able to drink a whole bottle of wine in a sitting and be just fine with a comfortable “buzz.” Even though I do not drink often, I did have two glasses of wine when out to dinner last weekend, and spent the rest of the night twitching in my bed until I fell asleep. I was definitely paranoid that I was going to have a seizure because of the twitches. I am going out this weekend to dinner and the comedy club for Valentines day/my birthday and will definitely space out 1 drink at dinner, 1 drink later in the night at comedy club. I am not too happy about this, but like the affects of the Wellbutrin better than being able to drink. Also, I have noticed that my patience with my two-year-old has a smaller threshold, as I do get mildly irritated easier. I am wondering, though, if anyone has experienced a seizure as a result of drinking 2-4 drinks of alcohol while on Wellbutrin. It says everywhere not to STOP drinking suddenly while on it, but what about having a few drinks? I understand that the affects of the alcohol worsen.

February 12, 2011 at 5:37 pm
(273) Deanna says:

I am on Wellbutrin XL 150 mg for depression issues. I have always been able to drink A LOT for a female without experiencing a hangover, getting sick or blacking out. Last night, I had 4 glasses of wine and a margarita. For me, this normally wouldn’t be an issue the next day. Not the case! I woke up this morning with the WORST hangover accompanied by MAJOR depression, crazy thoughts and disabling anxiety. (Blurry eyesight, poor concentration, irritation and anger as well.) It was so bad that I started to cry and become very scared. I had to take a Xanax to calm myself down. I am so thankful I found this thread. I Googled mixing alcohol and Wellbutrin and was SO relieved to have an explanation. Never again will I drink!! I feel SO bad and I mean bad to the point I thought I was going to have to go to the hospital and get sedated. My husband is out of town today and I am at home alone with my four kids. It has been a scary day!! DON’T MIX WELLBUTRIN and ALCOHOL!!! It is not worth it! I couldn’t even work myself through the acute anxiety. Terrible, people, TERRIBLE! Anyway, this has been a long thread and I’m thankful. It was helpful to me and calmed me down to finally have an explanation. Thought I would throw my 2 cents in there for anyone else who wakes up and can’t figure out why the hell they feel so mentally and physically crapped out on just a few drinks. I will say, the Xanax was a life saver along with lots of high protein foods and water! Looking forward to getting through these next few days so I can get back to my “normal” again! Lesson learned!!

February 12, 2011 at 11:32 pm
(274) Alden says:

Finding this message board has been so helpful to know that others are going through the same thing. I’m a bit surprised though to find that I’m on one of the highest dosages on here.. I’m a 21 year old girl, 5’4″ and 120 lbs and I take Wellbutrin XL 450mg. I’ve been taking it for about 4-5 weeks and gradually built up to this dosage. I had a terrible experience w/ drinking as well.. I didn’t drink very much and had an emotional and violent episode that I do not remember at all. I’ve drank since then and was really careful to only have 1 or 2 drinks. It kind of sucks having to worry so much about it because I don’t want another episode to ever happen again. It’s worth it though if the meds end up helping.

I take the Wellbutrin for depression and ADHD, but it hasn’t helped my ADHD symptoms at all so far. My psychiatrist is considering lowering my dosage to 300mg and then putting me on adderall (which I used to take as a teenager) to help with it. Has anyone else had any experience with taking ADHD meds with the Wellbutrin? Adderall worked great for me before, but I’m a bit worried now how it’ll affect me if I start taking it again.

February 18, 2011 at 11:00 pm
(275) winniethepoo says:

Wow – i wish i had found this forum earlier … i finally looked it up today after being on wellbutrin (100mg twice a day) for 6mths and really sick of having terrible hangovers the next after only a couple innocent drinks out for dinner etc! And when I go out on the town and loose track of how much i’m drinking because having too much fun to realize the next day i’m bedridden and its terrible. So after googling “wellbutrin & hangover” and finding this blog its so nice to read that soooo many people experience the same thing and i am just one of those people that can’t drink on it. Luckily i’m going to come off of it before the summer and will get back on the bandwagon … just really looking forward to having a couple drinks and not feeling like dog shit the next day! I now just avoid going out since I know it will be hard not to drink … boooooo…. but i guess i’ll save some $$!

February 22, 2011 at 3:23 pm
(276) expensiveDate says:

I too had to google this up after this weekends’ experience, and I’m glad I found this forum!

I was on “Zyban” about 10 years ago, 300 or 450 mg per day, I can’t quite remember. I do know that I had some whacked out experiences that I couldn’t remember when I mixed it with alcohol.

This time around though, I’m not taking it for smoking cessation, I’m just hoping for a bit of a tweak in the right direction regarding what we assume is depression.

It’s only 150mg XL. Once a day. And what I googled was “Can’t get drunk on Wellbutrin”.
That’s right. I’ve only been taking it for 4 days now, but on the 3rd day I was drinking in the evening. One beer, 2, 3… 4… some wine… some vodka…. NOTHING!
I simply couldn’t seem to get a buzz on. Seriously, couldn’t get drunk.
However, by the end of the evening, even though my brain “felt” sober, I was having trouble keeping my balance.

So I think yes, Wellbutrin does have some whacky effects on alcohol consumption. I think if you drink enough to the point where you would normally pass out, the Wellbutrin keeps you animated. Zombie like. A raging Zombie, perhaps, but still some screwed up animated unconscious thing.
I’m corking the XXX jug now, and keeping it that way.

February 26, 2011 at 7:35 pm
(277) Harmony says:

I’ve been on Wellbutrin xl 150 for about a month now. I truly feel like the person I remember. I thought for a long time that that person was gone and there was nothing I could do about it. I like to drink, particularly in social settings. I’ve noticed I feel more hungover than I used to on a comparable amour of alcohol. The first couple weeks I could still consume the same Amount, would just be hungover the next day. I did not experience any affects past the next day and I wouldn’t say that I was more depressed. I felt more dazed and had a splitting headache. I’ve noticed since being in week 4 that I feel the effects of alcohol much quicker. Two drinks and I’m feeling like I would after hours of drinking (5-7 drinks). You have to learn to drink in a new way if you’re someone who enjoys drinking. I do agree that the benefits of wellbutrin are far better than being able to drink large quatities. I feel a lot better knowing that many other people are having a similar experience.

March 1, 2011 at 4:51 pm
(278) kim says:

Thanks to everyone for your comments. I finally understand what is going on with me. As an extremely moderate drinker (couple of glasses once or twice per week), I have been on a terrible cylce of moods, blurred vision, desperate and impatient. For several years I did not drink at all and now realize that the combination of Wellbutrin and any alcohol for me is nearly deadly. Your comments helped me so much and I hopefully we are all on a better track.

March 5, 2011 at 8:13 pm
(279) Conn says:

I just increased by dose of Wellbutrin XL to 425mg about a week ago. Last night I drank and I barely remember anything. I woke up this morning with a terrible hangover. I made it through work somehow but I felt out of sorts and sick. When I got home I ate dinner and I started to feel nauseous. I vomitted. Literally ten minutes later I started to feel “cloudy,” dizzy, confused almost as if I was about to have an anxiety attack. The feeling was different though. I fell to the floor and my body felt stuck. My head was turned, I was screaming and crying uncontrollably. I could not move and my body was shaking. This happened for about two minutes. I did not pass out, but I could not control anything my body was doing. I think I had a seizure. Has anyone experienced this? I don’t know if I should go to the ER. I still feel strange and weak. I think I’m going to stop taking Wellbutrin altogether. I am terrified that this couild be an ongoing problem.

March 7, 2011 at 3:58 pm
(280) Nick says:

I’m only going to partially echo the same sentiment people have been expressing here. I’ve been on wellbutrin for just over a year now and, overall, its had a very positive impact on my life. My piece of advice when it comes to drinking on wellbutrin comes from limited experience drinking on the drug but I think it could prove helpful. For me at least the effect Wellbutrin has on me when I drink depends on the mood I’ve been in BEFORE I begin drinking. Coming into last wednesday I had just come out of a low mood swing but was beginning to feel much better overall. I had about 5 drinks that night and got plastered, browned out, puked, all of that jazz. The next day, yes, I felt super hungover with an upset stomach and annoying headache, but emotionally I felt fine. I know what its like to be in a deep, dark, isolated state of depression and I didn’t feel anything like that after last week. I must note though that was my first time having more than 2 drinks on the drug and the thought of alcohol still isn’t quite settling well with my stomach even 5 days after I drank. Despite the negative physical effects (which haven’t really bothered me too much), I am in a fine mental state, maybe even better than before last Wednesday. IN NO WAY, SHAPE, OR FORM AM I ADVOCATING THAT PEOPLE DRINK ON WELLBUTRIN! This was one experience and I thought it may put a different perspective on the matter.

March 7, 2011 at 6:35 pm
(281) Tex says:

My 47 yo gf has been on 300 mg WB/day for years…we began dating a year ago. She likes to drink wine. Alot. She is a physician in a pretty high-stress situation. When she drinks, she gets sexually aggressive. For example, I took her to meet my family Thanksgiving and she had too much wine: big mistake. Before the night was over she was dirty dancing alone in the fam’s living room and was pretty inappropriate with some people…I almost put her on a plane the next day. From time to time, it just appears -OH renders her really sexually outgoing in a way that others notice but she fails to get.

Other times – when not drinking – she is spontaneously irritable, combative even. Completely out of the blue. And she takes about 20 minutes to wind down from this kind of outburst.

Anyone have any thoughts about alcohol, WB and sexually innapropriate behavior?

May 22, 2011 at 2:27 am
(282) amanda says:

yup, cheated on my boyfriend during one of my many blackouts because of WB and alcohol.

Also, if you’ve got an addictive personality and drink on WB it gets really bad long term. Sex and drugs feed your brain dopamine, and WB can mess up your dopamine reward pathway if you’re used to seeking anything to get it going. even when im not drinking, i’ve changed to have zeroooo sexual inhibition and guilt association with sex.

March 22, 2011 at 4:32 pm
(283) lea says:

I know this is bad but I’m so thankful to see that it just wasn’t me.
This was probally the scariest night of my life. I was with my current boyfreind and his family was gettin together and offered us some wine so I drank two glasses of wine (I take prozac and buproprian) & everything was totally fine I felt normal than everything went down hill and we went to his back yard and it was all dark and I took 6 hits of weed and I felt like I just woke up.
And everything was a cartoon and my vision was going back and forth and I culdn control myself so he rushed me upstairs and we jus layed in his bed and I was freaking out so bad it was so scary I couldn’t talk but only in my head and the scariest part was, if I closed my eyes itd show me a universe and itd start spinning really fast and the faster the universe sped, the faster by heart would speed.
So I though if I closed my eyes I’d have a heart attack cause my heart was beating like no other.
So my vision was so crazy I ended up throwing up than finally my current boyfreind took me home at 11 and I culd feel myself think but I was exhausted and numb than I could finally go to sleep.
Its been a week from than and my whole body is numb, my heads killing me and my vision is blurry.
I’m scared cause I’m thinking did that one night mess up my brain.
Cause my dreams are fast and I can’t comprehend them and my vision is blurry.
I don’t know what’s going on.
But that was the scariest night of my life.
Never ever ever drink and smoke weed while on a anti deppresant.

March 23, 2011 at 11:42 am
(284) webster says:

So pleased to have found this thread. I wish someone had told me before! Since starting wellbutrin xl in August, I have become impossibly sick everytime I drink. No amount of any hangover cure seems to help the next day. I am totally out of it for 24 hours after. These stories are enough motivation to not drink anymore while on this medicine. It’s just not worth it.

March 26, 2011 at 4:42 am
(285) Pam says:

Like many of you, I am quite a heavy drinker who does not experience blackouts and rarely has hangovers. I have been on 150mg for about 5 weeks now, and I have had 2 absolutely awful hangovers after just a few drinks. I was vomiting all day into the evening. Nothing would stay down, and I felt like my insides were leaking into my body. It’s not worth it. My tolerance used to be quite high, and now after a few, I feel like I lose control. I don’t want to get to the point of blackouts and doing things out of the ordinary. Thanks for sharing.

April 9, 2011 at 9:32 am
(286) Ashley says:

Question – I just started taking it for ADHD. My 21st birthday is in two months. Would I be ok if I just skipped the dose on that day? I mean I’m only taking it for ADHD, a day without focus won’t hurt me bad at all.

April 20, 2011 at 4:21 pm
(287) veronica says:

no it does not leave your system overnight. You would need at least a week off it, but depending on how long u been on it then u need to ween off of it. But thats another issue.

April 12, 2011 at 7:00 am
(288) brandy says:

i went through an insane exzperience on welbutrin so i quit taking them, i blacked out after about 5 shots and im one of those ppl that drink alot and it takes me 4ever to get drunk, ive been on welbutrin xl 300 for over 3 months and drank all the time, anyway, i blacked out for 14 hours, i dont rememeber anything that happened, but apparently i cussed my husband out beat him up and threatened to kill him in his sleep, i was throwing glass cups at cars driving by, i was tipping over all the furniture in my house and telling my kids it was an earthquake, i was running around my neighborhood thinking ppl were chasing me, i was calling ppl and threatening their lives, they said i was viloent the whole time and acting crazy. they should have tied me up and put me into a room until it was over, and when i came too at 5 am, i felt refreshed like i slept all night so i didnt go to bed till the next night, and i didnt remember that my husband left with my kids because i was acting crazy, i remembered nothing and was asking alot of questions, but yet everyone thinks i was drunk and completly in the wrong so i felt guilty for days now, but how can i be wrong when i was never warned and had no idea what was going on or that i was even awake. DONT DRINK ANYTHING ON THESE PILLS, ITS NOT WORTH THE RISK OF BEING THAT CRAZY AND VIOLENT AND POSSIBLY KILLING SOMEONE

April 20, 2011 at 4:31 pm
(289) veronica says:

1 wk on gen w, have plans for the weekend but am rethinking the drinking now. Some stories are so scary and horrible. The behavior of some reminds me of mine on ambien, like being sexually inappropriate and posting comments on facebook.

April 27, 2011 at 9:42 pm
(290) betsey says:

I have been on Wellbutrin 150/day for a long time and have no problem drinking as much as a bottle of wine a night or a few cocktails per night. Still feel fine. Make it to work on time every day and am productive and happy all day… what’s wrong with me???

May 11, 2011 at 10:03 am
(291) Summer says:

I just started 150 XL a week ago… on Mother’s Day we had a bbq and I started drinking at noon and continued to do so until midnight and could NOT get so much as a small buzz, only a headache. I was a big drunk for 10 years but it’s like since I’ve addressed the depression and anxiety (also on Buspar for that) I don’t have the urge to drink 10-15 beers a day, I still have 1-3 on most days and can’t even catch a buzz so I just don’t worry with it and I go to bed. Wonder why it seems to be the opposite for me…

May 11, 2011 at 4:22 pm
(292) Morgan says:

I am on 150/day and I take it before bed…I have taken every med out there and have never noticed a side effect w/ my drinking, or at least didn’t associate it. I drink 1 -3 glasses of wine per night typically and more on the weekends. Rarely hungover.

I just realized that I have been hungover more in the past 2 or 3 months than I have been in a year. If I stick to just 2 glasses or so I seem to be fine, but if I overdo it all I’m stuck w/ a nasty hungover fuzzy feeling all day, and it doesn’t get better it gets worse as the day goes on.

I am thinking it has got to be the Wellbutrin (started about 3 or 4 months ago) I take it for social anxiety issues, and it helped me quit smoking (yeah!) and I don’t seem to have any side effects. I thought it was just because I was getting older (just turned 30) but now I really think it’s the meds!! I enjoy my couple of glasses of wine and I don’t want to feel like shit if I overindulge a little!!

I might seriously consider switching medications because of this….Then again I guess cutting back on my drinking is not a horrible idea.

May 16, 2011 at 6:24 pm
(293) Alexx says:

Ive only been taking Welbutrin for a few weeks, along with a mood stabilizer.. and up until the other night i hadnt drank anything while being on them. I had a good deal of alcohol, but the bad thing is is that it made me dreadfully ill, and i dont even remember going home… ive been puking for two days now, easy to say… i wont be drinking on this again.

May 20, 2011 at 10:14 pm
(294) Madava says:

Why even attempt to drink alcohol if you are using the anti depressant?!?!?! I KNOW you guys aren’t stupid enough to be taking an anti depressant and then consuming alcohol which IS a depressant.
There is warnings not to be consuming alcohol with Wellbutrin…doesn’t anyone read up on things they consume anymore? You’re on the internet typing your comments on here, take the time to read the history and effects Welbutrin can have….

May 24, 2011 at 3:24 pm
(295) lindz says:

Same old story. alchohol and wellbutrin dont mix for me either. The problem is I feel social drinking is an unavoidable part of my life. Does anyone know if skipping a days dose is ok if your planning on drinking that night ? im sure its not but just a thought. also has anyone had any luck on anything herbal ?

May 28, 2011 at 3:37 am
(296) goodeating says:

I have learned this lesson the hard way. As someone that works in the restaurant industry I am used to beer and wine on a daily and moderated basis. That was until I started wellbutrin. It has turned me into a bad natured jerk so Im told on account of me having NO recollection of the events the night before. It has damaged relationships on three occasions even after as little as two standard drinks. Now I just stay away from alcohol all together !! BE WARNED….Its different with wellbutrin!

May 28, 2011 at 2:17 pm
(297) rosy says:

I’ve been taking 150 mg of Wellbutrin XL for almost a year. It has really helped me. I only ever drink one beer/mixed drink at a time. I haven’t noticed any effects. Although I haven’t monitored if the depression worsens. It is good to know that this may be the cause of my occasional lows. They don’t always occur close to or during my period. I will have to make sure I don’t drink much more, those stories are scary! Info is good to know, thanks.

June 11, 2011 at 4:32 am
(298) lisa says:

Day 2… feeling much better… although I can’t sleep and loss of appetite. Will this subside? And why aren’t doctors warning patients???? Definately not gonna attempt the mixture, due to attempt of suicide and dui from mixing other AD’s with alcohol (paxil and zoloft)… not a good combo. Just glad I found this b/c now I understand past experiences I’ve had similar to these. I can’t believe after all these years I’m finally discovering what caused these insane behaivors and how clueless I was about mixing AD’s with alcohol.

June 19, 2011 at 1:37 am
(299) Erin says:

I’ve been on WB 100mg/day for four months. I enjoy one or two glasses of wine a few days per week, as I am a member of the industry and frankly, it’s my job (and passion.) But – I have not, ever, ever gotten drunk since the day I started this drug. In fact, I realized I haven’t had a hangover since the holidays (before WB.) In my experience, my doctor informed me that moderate drinking is OK, and I’ve stayed away from hard alcohol almost completely (if I do have one, it’s ONE…no more.) I haven’t noticed anything strange after two glasses of wine, but that’s just me. I’m in my early 30s and my heavy drinking college days are far behind me, (not to mention that drinks equal calories) and am hesitant to drink more than I do. Glad I found this comment feed, it’s best to hear experiences from fellow WB users over generic prescription warnings.

June 26, 2011 at 11:29 pm
(300) Neenee says:

The combination of WELLBUTRIN and alcohol CAN be devastating. While different people react differently, my husband is on Wellbutrin and recently has been drinking to excess.

His behavior is bizarre, aggressive, inappropriate, and paranoid. He does crazy things at night and has no memory in the morning. This intensifies his paranoia, thinking I am breaking things, putting his car windows down, tearing up the house, hiding his keys, etc… To make him think he’s crazy.

I can not get him to seek help. He gets drunk very easily, but also does not pass out or stop drinking until he has been awake for 48 to 72 hours… Then spends days in bed recovering.

While he is under the influence, he hits people, drives his car, makes unwanted phone calls, starts arguments — every sort of ridiculous drunken behavior imaginable. He is a danger to himself, to me, and to our community in general. But again, he will not get help, he thinks the problem is with me.

I cry and pray for anyone else who has had similar experiences. This is a terrible tragedy, and I am helpless to do anything but watch the man I love self-destruct.

June 27, 2011 at 1:07 pm
(301) Amanda says:

I recently started taking Wellbutrin, and it was working pretty well. I increased to 300mg from 150. At first I did not drink any alcohol at all, but then I tried a few glasses of wine, and I was fine. So I assumed that I could drink with no problem. Bad idea. Some friends and I drank tons and tons of tequila. I ended up marching topless in a gay pride parade then blacking out for about 2 hours. I have no idea what happened during that time, all I know is that I was wandering alone around New York City and was found puking on someone’s doorstep. I remember things in flashes. I remember it was nighttime and I was in the back of an ambulence. I remember my friend magically appearing and taking me home. I woke up the next morning with a bloody knee, puke on my shoes, and a swollen eye. I had blurred vision for about 24 hours. Really really scary. Also, apparently someone who works with me saw me topless. Embarrassing. Please do not drink on Wellbutrin. I have definitely learned my lesson.

July 2, 2011 at 1:46 pm
(302) 62224 says:

drinking on wellbutrin made me extra anxious
i couldnt stop moving my legs. and it felt like a bowling ball of butterflies was sitting on my bladder. if that makes sense. sounds horrible right?
that was my first experience drinking on wellbutrin (i just started about 2 weeks ago)
i probably wont casually drink on it again

good luck

July 4, 2011 at 12:55 pm
(303) Kenzie says:

DO NOT EVER DRINK ON WELLBUTRIN!! please listen to my advice. I have been on this drug (300mg xl) for 5 years. It definitely reduced my alcohol tolerance significantly, so I used to get no more than three drinks. Sometimes three drinks and I wouldn’t feel a thing. Other times I was legit wasted. The fact that I never know how I will react, still, after years of drinking on this drug is frightening. But this past Friday I had the most terrible drinking night of my life. 2.5 drinks. Not only was I wasted, but I blacked out, passed out, woke up covered in myown vomit, was speaking complete gibberish and I actually attacked someone and was dragged out of the bar (luckily I’m a 115 lb female so I wasn’t doing any damage!) Bottom line, if there can honestly be THAT much of a spectrum of drunkenness off of under 3 drinks, this is not safe at all. Luckily I was with a friend who took care of me but I don’t even want to think about what could have happen. I officially quit drinking not even one. PS I always drink the same type of hard alcohol so it wasn’t a matter of beer versus tequila or something.

July 5, 2011 at 7:37 pm
(304) Mat says:

Ive been on WB XL 450mg for about a year. Periodically, I have been having major excessive sleep issues; ie, sleeping soundly for 10 hours and waking up feeling exhausted. I never put two and two together until today. I had five beers last night during our July 4th block party. And slept until 1pm on a workday. It’s now 4:30 and i could go back to sleep right now and sleep until morning. Anyone else experience this?

July 7, 2011 at 6:28 am
(305) Matt says:

I’ve been taking Wellbutrin XL (generic 300mg 1/day) again (it’s been the only AD that seems to help with my depression) since May. I am also taking 10mg Abilify in the evening. I’m 25, and have had an on-and-off again relationship with alcohol, meaning, I’ve gone through periods where I drink a lot (self-medicate when I wasn’t taking meds). This pattern hasn’t helped me, which is why I’ve gone back on my BP meds and tried to stay away from booze. On the rare occasions where I’ve had alcohol this summer, it has been fewer than five drinks in a night, and over a longer period than in the past. Always, ALWAYS, I get sweats and a terrible headache several hours after finishing the last drink. Last night, I had two pints of a lager beer which got me a little buzzed, but also really cloudy-minded. Three hours after the beer, I experienced sweating and a headache that persisted (I had consumed a lot of water) up until I fell asleep. Woke up today feeling refreshed, as I normally do with Wellbutrin, but also a little cloudy still. I’m not really complaining because making drinking less rewarding like this is cheaper and safer than if I could drink as much as I wanted without the somatic effects. Also, I’ve noticed that I don’t get the “up” feeling I used to with Wellbutrin…and sometimes have really bad moments of dysphoria every other week or so…I’m hesitant to change to another AD (might swap out abilify as it’s rather pricey) as Wellbutrin has a lot of good stuff about it…

July 17, 2011 at 7:13 pm
(306) Dan W. says:

I am so glad I have found this website. I was really beginning to wonder was I going crazy, had something gotten so miswired,that I was never gonna be able to fix it.

I have been on Wellbrutrin XL150 for just over a year. Drank fairly regularly (1-2 shots of rum, 3 to 4 times/week). Reduced that when I started to see that it was going to get worse before it got better.

When I was prescribed the medication I specifically asked about the mixing of Wellbrutrin and alchohol, told it was no problem and infact after my recent experience double checked both the Wellbrutrin Web site as well as the Wellbrutrin entry under Wilkepedia, in both cases nothing about alchohol consumption being a problem. When perscribed the doctor advised that if I was having a blue day, that it would be okay to take a second pill, so I went to my annual conference this week. Tuesday at a dinner out, I consumed probably 2 rum and diet cokes, two glasses of wine and perhaps before dinner consumed a double in my room with a workmate. Wednesday went to the workshops felt off all day, a little blue, and so following a single rum and diet coke I took another pill, went off for the barbeque. Consumed at least two other drinks there and then I guess all hell broke loose. I used inappropriate language, talked to some ducks at the waters edge for sometime, none of this is remebered. My workmate a subordinate and another showed up in my room the next day, and I yelled at them, to leave me alone, felt very sullen, angry helpless and exhausted until even today (Sunday). I like what Wellbrutrin has done for me, I don’t know if I ever want to get off of it, I sure as heck don’t want to ever expereince another blackout, its like people don’t believe you, thank you to all for being so honest, others like myself appreciate it. Good bye to booze, did not need it anyway, I can be the DD going forward.

July 23, 2011 at 10:37 pm
(307) Jeff says:

I’ve been taking wellbutrin for about 2 1/2 years now (300 mg), and i drink ALOT. Just over a year ago i quit smoking weed and cigarettes, and because i was so used to having a high every day i started drinking heavily, and have been an alcholic since then :S. I usually have about 10 – 14 beers a day or around 75 a week, plus i drink strong beer at 6.1% alcoholic content and i can handle myself well. Even though i know this is very unhealthy, i’ve never been affected badly by the combo as long as i start to drink an hour or too after taking my pill. So if you’re having bad effects from the combo it could be becuase you’re drinking at the same time as you take your pill, or taking it to close to the time you start or finish drinking.

July 23, 2011 at 10:43 pm
(308) Jeff says:

If anything, wellbutrin alone has worse effects on me. Sometimes it makes me feel out of it, so i actually only take it every two days (i’m not sure how healthy that is), but if i go any longer i get heart pains. The only time i had a bad experience with the combo was when i forgot to take my pill and was drinking earlier in the day, and even though i was sober i guess it was still affecting me cause i got this weird feeling like everything in the world was sped up. It was messed up. The other problem i get from wellbutrin is when i try to sleep within a couple of taking it, i get these messed up head and body rushes at the moment i’m about to pass out, which wakes me up again and happens continously. When i do finally fall asleep, i realise that i’m sleeping but i still have this messed up feeling so i want to wake up but i can’t. I feel like i’m in a coma, and all i can do is struggle for a long time until finally something wakes me up and then i’m afraid of ever sleeping again.

July 26, 2011 at 6:49 pm
(309) September says:

Wow I have been recently prescribed Wellbutrin and I have a couple drinks a day for relaxation….it was given to me to help quit smoking….had it filled a few days ago but now I am terrified to even take it…reading what all of you had to say I will NOT take it I will go to Chantix!!! Thank you for this forum was helpful in deciding!!! Sorry for those of you dealing with the horrific symptoms!

August 5, 2011 at 12:21 am
(310) Chris says:

I found this all too late. I knew that anti-depressants and alcohol don’t mix but I never knew to this extent. Before on previous medication I drank and never had an issue. This pushed me up and over the edge. I’m usually a case to myself guy. One beer on my 150 mg tablet and I was acting ridiculously drunk. This is scary… Definitely something I won’t do again.

Please Everyone Be Careful!!!

August 13, 2011 at 12:36 am
(311) A says:

If your young (18-25) and you are on these type of AD meds and drink a lot you WILL be sorry later on in life.

I am now 34. When I was 21-25 I drank heavily while on many of these meds (including Wellbutrin) I had multiple siezures and many trips to the ER for poisoning. Basically ruined my life.

Today I am suffering from many psychological diesases and every Dr I have been to CAN NOT diagnose me properly because I have too many different symptoms. The reason for this is because I have DAMAGED MY BRAIN. When I was young it was just depression and some anxiety….now I have SEVERE depression, anxiety, auditory & visual hallucinations, toughts of suicide…the list goes on.

I have been told by many of the top Drs here in NYC that I have permenatly damaged myself.I mixed meds and alcohol so much that it will take years to recover, if ever.

A few years of drinking is not worth a lifetime of illness. Trust me please.

I am currently on Wellbutrin, Lithium, and Liamitical.

August 24, 2011 at 12:02 am
(312) jon m says:

im on wellbutrin for adhd still no drinking or only if on it for depresion

August 29, 2011 at 12:08 pm
(313) AP says:

I, too, am happy to have found this thread. I have been on buproprion SR for the past few months and have definitely noticed that it takes less alcohol to get buzzed. Additionally, I have found that if I drink too much (which is only maybe 3-4 drinks with the increased alcohol sensitivity) I am become very outgoing, and not always in a good way. I don’t get angry and violent like others here, but I become very flirty and sexually bold, which sounds fun, but really doesn’t bode well the following day. I have engaged in some behavior which is really embarassing. I really don’t want to quit drinking and will likely to continue to have my glass of wine or two every evening, but I am going to be more mindful when I go out on the weekends, etc. It’s like I have absolutely NO inhibitions at all.

September 2, 2011 at 7:22 pm
(314) Tessa says:

I’m not sure if I’m happy I found this thread…I feel perhaps it might make me paranoid. I’ve been taking Wellbutrin 150 SR (generic) for 2 months now. And I haven’t had any of these excessive hangover/bizarre experiences…so Wellbutrin hasn’t affected my drinking – I just don’t feel like Wellbutrin has had ANY effects. I feel depressed all the time, and just cry for no reasons. I took Cymbalta for 8 montsh before, which made me feel emotionally empty and numb (I didn’t cry for the whole time I took it, even at things that warranted a good cry). But on Cymbalta I was always exhausted and could barely get out of bed in the AM. On Wellbutrin, I seem to have more energy and can get up, but I feel so sad all the time…

As to drinking, I do drink almost every night (1-2 glasses of white wine). I never felt any different while drinking nor hadve had any wicked hangovers. (FYI: I am 30 yr old female, 150 lbs, exercise 5 days a week.) Now after reading this thread I wonder if this is why the Wellbutrin hasn’t had any effect on the depression. I would prefer not to stop with the wine, as I have a highly stressful job, elderly and sick parents, a husband who just “doesn’t get” depression and puts a ton of demands on me, and within the past 2 years I have relocated to a place where I’ve had a hard time meeting anyone, so that 1 glass of wine is the best part of my day. Sad, I know, but that’s how the cookie crumbles.

Is there any scientific/medical research that shows that alcohol (even when taken very moderately) coinciding with Wellbutrin does not necessarily intensify the effects, but simply causes the Wellbutrin to just…not work? Cancels out all benefical effects, so to speak? I appreciate any answers anyone can provide.

September 2, 2011 at 10:56 pm
(315) AP says:

I am not sure about hard scientific data, but I would agree with others who have posted that drinking can indue greater depression the following day. But mayb wellbutrin just isn’t doing it for you. I was actually on zoloft and wb to counterac sex side effects of the z. I quit the z because I was worried about weight gain and now I cry more.

September 3, 2011 at 9:11 pm
(316) Dora says:

Folks – I can see by a lot of the comments that people are used to drinking a “few beers” and maybe a shot or some wine too. Maybe you are just feeling hungover? Maybe you are getting older and feel the pain more? I have been taking Wellbutrin 300 for a few months. I love the drug. It has been a blessing. But I used to abuse alcohol too. Now I can’t drink even one beer without having a bad mood swing. I don’t feel great the next day either. If I have two wines I am sick the next day. I lost 23 lbs on the drug, now weigh 125. All the more reason I cannot metabolize alcohol the way I used to. No loss believe me. My point is if you stop drinking so much – maybe stop drinking entirely – you will reap the benefits of the drug. Hard to give up old habit isn’t it? Maybe all that drinking is a symptom of your depression? Good news – you don’t need it anymore. So let go.

September 18, 2011 at 12:00 pm
(317) PhillyGuy says:

Sorry Dora, that was supposed to be a post, and not a reply to your post.

September 29, 2011 at 9:33 am
(318) LR says:

Thanks Dora, you’re totally right!!

September 18, 2011 at 11:56 am
(319) PhillyGuy says:

I can not believe people will start taking an anidepressant, and continue to feed their body with a depressant.
Read your script! It will clearly tell you that drinking alcohol is discouraged, with this medication.
Maybe take the money you are spending on alcohol, and use it on talk therapy, along with taking your Wellbutrin?
If getting “better” is your goal, while taking this medacation, give it a chance to help you make the smart choices most of us haven’t been making.
This medication, along with therapy, has hellped me change my life in a matter of months. I started at 150 XL then up to 300XL(1month later). I stopped drinking about 3 weeks before I started, and stopped smoking the day I started. My mental state has improved greatly, I think clearly, and have been making smart life choices, improved relationships, and much better self worth, and many old tasks take a lot less energy out of me.
Drinking Alcohol, is often a band-aid to ease the pain of a much larger problem, that many times we aren’t aware of.
I think if you are taking Wellbutrin, you deserve to give yourself and the medication a chance to do its job.
I wish you all the best that come across this thread. Most of us got here because we are suffering, and we want it to end……Wellbutrin, if taken properly can help that suffering to improve and/or end. Sometimes if you want something to work, you need to work it, as well.

September 18, 2011 at 11:47 pm
(320) Vanessa says:

This thread has been extremely helpful in making me realize that my erratic behavior and blackouts are due to this combo of generic bupropion and alcohol. I’ve been taking 450 mg of the drug for years. I had a period of time when I was drinking a lot and getting crazy and doing really stupid things. Now I think that was because of this. Last night was the worst though – I drank a whole bottle of wine myself, then a few whiskeys. I remember flashes of last night but I can’t figure out what happened. However I know I was naked in some random guy’s (not my boyfriend’s!) bed and walked home barefoot carrying my shoes (in NYC – not smart). I got home at 8 am and today I feel like I got hit by a bus. Plus I have a lump on my head and a bleeding finger and I have no idea why. I vaguely remember being stopped on the sidewalk two separate times by the cops last night because I was acting so bizarre. I have no idea where I was or how I got there, plus I don’t know who this guy was. This is a nightmare. I am happy I got home in one piece but of course I have other concerns to deal with. I definitely will be laying off the alcohol.. I can barely write this because my head is so foggy.

September 29, 2011 at 9:31 am
(321) anonymous says:

I’ve been taking wellbutrin 150 for about a month now. I have noticed some great changes like its easier to eat in moderation, it has helped me not smoke as much, i have more energy and a better outlook on life, and I havent had as much of an urge to pick up a drink. unfortunately though, it took me a few weeks to put the pieces together. if i drink at all, i become angry, confrontational and depressed. i had two beers last night and i ended up fighting with my partner and crying and the next day or two i am so depressed and have a terrible outlook on life. i cant even tell you why we were fighting, it was that stupid. if you’re serious about kicking your depression and making serious life changes, dont drink alcohol with this medication. They need to put a better warning label on the medication.

October 2, 2011 at 2:11 am
(322) Adam says:

Hi All,

Good to see this thread. I was contemplating how much I would drink even though my psychiatrist said only 1 or 2 at most. Now I don’t think I’ll exceed that limit and maybe not drink even that much. I’m 28/male and it’s part of my weekend so I am really upset about not fitting in, etc. What I’d like to know is what do you tell people out at bars and other places that everyone has a drink in their hands? Any tips or tricks? I don’t necessarily want to tell a girl I’ve only known for 5 minutes that I don’t drink because it doesn’t mix well with the medicine I’m on. . .


October 2, 2011 at 6:36 pm
(323) Love says:

I take 150mg twice a day plus 10mg risperdone… I felt like getting drunk after several months of not drinking…I got me a 12 pack of natural ice…I know the beer tastes like crap but after 3 or 4 who cares…I’m cheap when it comes to money…lol :) I drank it all by myself at home alone…I still can’t find my shoe or one of my cordless phones & I broke my keyboard & my furniture was turned upside down…It was a heck of a job cleaning up…Plus I called somebody about 10 times late at night…I have no idea what I said & I’m scared to ask so I’m avoiding them…It took me about a week or two to get back to feeling normal…I felt like checking myself into a mental hospital there for awhile…Don’t do what I did & binge drink, very bad combo…I’m such a nutjob & I knew better, but the voices in the back of my head didn’t care…lol :)

October 2, 2011 at 6:45 pm
(324) Love says:

That was suppose to be a post not a reply…Silly me…lol :)

October 4, 2011 at 8:45 pm
(325) ELQuillotano says:

Hi Everybody,
This website has helped me a lot over the last few months. PLEASE DON’T DRINK ON WELLBUTRIN! I’ve been on Wellbutrin for a couple months now. The first 2 weeks I had some crazy side-effects like I couldn’t sleep and I was having hallucinations. After the first couple weeks, those side-effects went away. Since then, wellbutrin has helped me tremendously. I don’t wake up depressed anymore, and I’m able to leave my house. I did drink on it before and that is a terrible idea. The next day I woke up severely depressed and it took a few days to get back on track. Overall wellbutrin has helped me a bunch to beat my depression. The other useful things have been gentle exercise and less TV and video games. Going for long walks helps a bunch because most people can walk longer than they can run. Walking can be a great distraction and it is great exercise. I used to be so discouraged when I would try to exercise because I was in such terrible shape. But just going for a walk is not as challenging as most exercise and it was literally the first step in helping me feel better. I was so severely depressed I could not function at work. I LOST MY JOB (pretty much because I couldn’t function)…I barely left the house for like 2 months…Talk therapy helps too. It’s funny the first time I went, the therapist asked me simple questions about my life AND I JUST STARTED BAWLING MY EYES OUT … Weird I thought, but again it was a crucial step in the long process of getting my life back together. Overall if you are depressed PLEASE DO NOT DRINK ALCOHOL! It’s dangerous and it will keep you depressed for longer. Good Luck everyone! I hope we all feel better soon…. Start by taking that first step, and go for a walk around the block.

October 6, 2011 at 9:44 pm
(326) Gary says:

Thought I would post as a long-time Bupropion user (9 years).
Drank to medicate for years and started anti-dep at age 39 (15 years ago). Started with Paxil- it changed my life. Still drank and found I could drink a lot more on it. Always was a drinker since college. Switched to other things after 4 years (weight gain, lost effectiveness).
Then 2 years after that added WB/Bup. Took 3-4 different meds with it and found it was not effective (nothing brought back the euphoria of the first 2 years of Paxil).
Dropped all other Anti-Dep 4 years ago (i think) b/c of ED side effects (coupled with age!). Upped dose of WB.
Now to the drinking with just WB- bad hangovers. Not sick but lethargic and useless. For years now I’ve been saying “i’ve got to stop drinking”. And actually I vomited a few times after 7-9 drinks.
Boy have I slowed down on the drinking. And I say Thank You to Wellbutrin. I just as soon not drink like I used to. This med makes me not want to drink (I did fight it though!). Never drank more than 9-10 drinks in a 8 hour marathon but more and more I can’t take it.
I’m 54 now and the body slows down. But I really believe the Med multiplies this effect.
Looking back, I had a very bad experience I did not link to the med. I think it was when I limited myself to WB. Drank a bit but I actually passed out in my car for 2-3 hours. Left the a/c running the whole time. Managed to drive home.
Was very sick the next day, slightly better sunday but then felt terrible for 4-5 days. Thought it was a flu but it was something I never had before. I’m never down that long.
I just figured this in retrospect after reading the posts. It still haunts me 4 years later.
Bottom line- Stay on the WB and really limit drinking. You all know that is the best thing to do.
Good luck and God bless all readers.

October 9, 2011 at 10:12 pm
(327) Addie says:

Hi all,
After reading all these comments, I feel so much better about my experience with buproprion and alcohol.

My caution to everyone is that its possible for the first few months to have no new reactions to alcohol…but after the drug has built up in your system things change and change quickly. I can hardly have 3 drinks without blacking out and becoming violent. When I first started taking the drug, I drank like normal and everything was fine… But after about 2 months, it hit me hard. Thinking I could manage it with moderation, I continued to drink, only lighter. It wasn’t long before my modified drinking became a problem as well. Like everyone else, it made me depressed for longer too.

Not a good combo! I would not recommend drinking while on this drug!

October 10, 2011 at 8:26 pm
(328) Kelly says:

I’m so glad that I found this post. I’m a 34 year old female and I’ve been on Bupropion for the last several years. I’ve had some horrendous experiences that I had not attributed to the drug/alcohol combination. I almost always black out while drinking any more than 2 drinks. A couple weeks ago I had way too much to drink at a friends birthday party and the next day, I didn’t remember anything and had the worst hangover of my life and severe paranoia. I read through every post and thank everyone that has posted. I noticed that most people post on here immediately after a bad episode of combining the alcohol and medication. The one thing that I did not see is anything that can help ease the distress. As many of you mentioned that these horrible feelings can last for a week or more. I’ve found that DRINKING FRUIT JUICE, LOTS OF WATER, AND TAKING A LOT OF B VITAMINS Really help to ease the effects. I am in no way reommending drinking while on the medication (in fact- I highly recommend avoiding the combination). Unfortunately, taking asprin, etc… only further damages your liver.

October 13, 2011 at 11:09 pm
(329) jd says:

Iím so glad that I found this fourm i been on WELLBUTRIN
for 5 weeks now i dont drink much at all just when i go out
with friends now and then and i was going to go out this week end and have a drink but after reading all the stories NO WAY
thanks every one for posting …

October 15, 2011 at 2:28 pm
(330) Randy says:

I take 1500 mg divalproex daily (P.M.) for mood and 200 M.G. wellbutrin twice daily, that is untill my DR. told me of possiable seziers and now only take the A.M. dose. Good thing I finally told my DR. how much I REALLY DRINK and that’s 8 beers EVERY NIGHT. Like others I too am lucky never to have had seziers. Do to my multiple sclerosis I’ve had serious problems with depression so to me it’s just a normal every day thing which, I believe explains why I’ve never really noticed any changes. Bottom Line, I have enough problems allready without worring about seziers, thank goodness for my DR. ALSO for people like you who may well someday change “A DOUBTERS MIND”.

October 15, 2011 at 4:45 am
(331) annie says:

I just started taking Wellbutrin 75mg twice a day 2 weeks ago. Now I’m on Wellbutrin XL 300mg. I’m kinda bummed that I can’t go out and drink anymore. I feel like life will be boring. I have ADD to so if I’m not constantly stimulated socially I get really bored and apathetic. I hope the Wellbutrin helps with my depression and anxiety though. I suppose its worth a try to quit drinking and see if this stuff helps. Ugghhh, depression sucks!! Why can’t I just be normal?!?!?!?!

November 8, 2011 at 6:40 pm
(332) steve says:

I started using Bupropion 3 months ago to help with smoking cessation, with a dose of 2x 150mb per day. While I have quit entirely for the last two months, my Dr. wanted me to stay on it to help with depression. Also, I quit drinking at the same time because she advised of some side effects (like feeling more hung over). Two very strange things I experienced on this medication:

1. After not getting enough anxiety relief (Bupropion does not help with this), I got back onto Cymbalta 60mg once per day, which I had taken before and seemed to work well for me with anxiety and depression. However, two days after introducing this new medication into the mix, I had an anxiety attack, which I had never had before. I had to take a clonozepam to get back to normal. But this did not continue to be an issue.

2. In the last two weeks, I did some things that really screwed up my mental well-being because of Bupropion. I had gotten some really good news, and then I went out with friends and drank quite a bit in celebration. Not black out drunk but beyond tipsy. The next day, I was a bit hung over, but not otherwise affected. I did not drink the next several days. However, after two days, I started to have the following symptoms:

-Feelings of euphoria and invincibility
-Fast talking, speaking more loudly, easily irritable with “slow” drivers or even just people walking
-Easily angered
-Inability to concentrate on a single task for any significant time
-Feelings that I had lots of energy; I stayed up for 36-40 hours at a time before going to sleep, and even then I would sleep for at most 6 hours.
-Very risky driving behavior
-Obsessively cleaning and organizing things
-Washing my hands way more often than necessary
-Spending sprees
-Feeling that I should “celebrate” and relax by having some more beers, or smoke a cigar
-Not feeling the need to eat much or have regular meals

[cont'd next post]

November 8, 2011 at 6:42 pm
(333) steve says:

-And, scariest of all: I did not want realize it was a problem, I thought it was awesome, I did not want to tell anyone what was really going on or they would make me stop. I thought I was just finally happy after being depressed for so long, and this was the “real” me.

I realized I had to get help after I said something horrible to my girlfriend. It definitely damaged our relationship, I don’t know if it will recover to be honest. But I did finally realize that I had to get back to normal. And I feel very lucky that I did not physically hurt anyone, or myself, from my reckless behavior.

I am very glad to have found this page because I felt like I was alone and totally crazy. My Dr. had said it was a bad idea to drink because it might affect me more and give me a worse hangover. But I did not know it would make me manic, and do all the things I did. I am grateful to share these experiences with everyone here. I know now how vital it is to never drink on Bupropion. That said, I would rather taper off of it and quit taking it, and take more Cymbalta instead if necessary. Realistically speaking, I don’t want to be socially awkward for the rest of my life, and I would like to be able to have 1-2 drinks at social occasions (i.e. definite moderation). I hope that some of these thoughts will help someone out there. Personally, I’m going to work with my Dr. to get off Bupropion because its just too risky if I slip up and drink.

November 9, 2011 at 2:29 am
(334) Erik says:

So I started taking bupropion (150 mg 2x daily) in order to help me quit smoking. However, at the same time I got on the pills (about a month ago) a whole lot of other bad, stressful things were happening in my personal life so much so i felt like I was on the brink of having anxiety/panic attacks. Furthermore, I tend to drink at least two beers/alcoholic drinks every night. Much, much more on the weekends and much, much more when I’m stressed…

Anyway, got on the bupropion and was concerned about the seizure warnings about suddenly stopping alcohol intake. So I decided to make it a strict 2-drink a night deal. For the first week, I could really tell that the alcohol was hitting me harder than before. However, after a few days, that went away and after my first weekend of 6+ drinks a night, was still able to feel decent in the morning. I did notice the effects on Monday, however. Feeling much more draggy and blah, like I had gotten sauced the night before.

It’s very weird but my sex drive is through the roof. Which is good times for the wife and myself. Seriously, I don’t feel like I’ve been this horny since I was a 7th grader (I’m in my 30s now). I guess my statement is that I really haven’t an issue with alcohol & bupropion. However, I would like to know if this sex drive will stick around while I stay on the pills… because I really, really, really don’t want to go back to the lackadaisical sex drive I had before I started this wonder drug… Any advice from someone whose been on this for a while?

November 11, 2011 at 5:43 pm
(335) Emily Rogers says:

This is odd, because I take 300mg of Wellbutrin SR (in one dose) and I have never experienced any problems with alcohol.

I noticed that many people on this board have just started taking Wellbutrin. I’ve been on it for about a year. I wonder if this is an effect that tapers? Not advocating for anyone to drink on Wellbutrin, just wondering if anyone else had a similar experience.

November 14, 2011 at 9:59 am
(336) David says:

My doctor upped my dose of Wellbutrin a few weeks ago. I feel great. I have noticed that when I even have one glass of wine now it makes me feel like crap and any alcohol tastes really, really bad. I know they use Wellbutrin to treat nicotine addiction but does it work on alcohol too? I used to drink heavily and now alcohol isn’t at all appealing to me. I prefer ice water.

November 26, 2011 at 12:48 pm
(337) Kim says:

My doctor just upped my Welbutrin to 400mg daily about a month ago. It’s made a huge difference with depression. Last night, at home, I had two glasses of wine went upstairs and at the top it hit me like a ton of bricks. I lost my balance and collapsed banging up my knee. It was like I’d had two bottles of wine! I’ve been lightheaded all day with no alcohol.
If you’re just starting wellbutrin procede with caution. From these posts it seems not everyone has adverse affects. I sure as heck did.

November 28, 2011 at 1:21 pm
(338) Matt says:

Just like everyone else here, I’ve found that WB not only dramatically lowers my alcohol tolerance, but also makes my behavior much more erratic and violent.

Normally I’m a very heavy drinker (was problem levels in the past), but almost always nice or at least well-natured even while wasted. However both times I’ve taken WB and drank normally on it I’ve wound up in physical fights over nothing, shouting at random people, not remembering where I was and the like.

Do NOT drink on WB, especially if you have any history of drinking for self-medication or emotional reasons. Your body and mind will NOT react as you’re used to.

November 28, 2011 at 8:27 pm
(339) Cindy says:

so if I am a regular drinker-several beers a night-is it safe to stop cold turkey,or better to taper off slowly?the warnings say not to suddenly stop the drinking. i am thinking i should taper off slowly…

December 6, 2011 at 5:01 pm
(340) Love says:

I take 200mg twice a day. I been binge drinking about 18 beers once a week. Don’t really have any hangovers. Just fill like sleeping all week until I get another 18-pack. I have no friends so I get on facebook & just say crazy things. I have a fake name on there so nobody knows who I am. But still embarrassing stuff. Like me writing on here. I’m thinking of getting some alcohol right now…I’m going two try not to drink for a couple of months & see if I feel like living again. I feel so worthless.

December 15, 2011 at 6:30 pm
(341) rjw says:

I had five to six glasses of wine of three hours while on Wellbutrin XL (150) and it really messed me up. Main effect was double vision. I have been Wellbutrin CL for about a month and did not see any side effects with an occasional drink. I will be refraining from multiple drinks.

December 16, 2011 at 7:36 am
(342) Liz says:

Wellbutrin and alcohol really don’t mix. If I have one glass of wine or one beer I’m ok, but if I drink a little too much I cannot sleep, I get the worst hangovers known to mankind and like others have said feel depressed for days. As a lot of you may know it is absorbed through your liver so when you drink it’s a double whammy

December 30, 2011 at 3:19 pm
(343) Mike says:

I started taking wellbutrin a couple of months ago and hadn’t had a drink since starting. On Christmas eve, last weekend, I had two vodka and sodas, normal-size shots not doubles, in about an hour and felt totally trashed and slurring. Felt like my judgment was poor and embarrassed myself talking with people who were present. Before Wellbutrin, I would feel a mild buzz on that amount, but no one would notice anything different about my speech or behavior. It’s kind of humiliating, not to mention that I don’t want to get that way from drinking.

Definitely not going to have a drink while on it again.

January 2, 2012 at 5:56 pm
(344) Traci says:

Wow! Am I glad I found site…It has explained a lot of my irrational behavior!!! On several occasions, I have blacked out not remembering getting home, taking pictures, dancing and etc. I have been crazy at my husband…like hitting him, saying everything mean I could think of, breaking doors in our house…he told me he was getting tired of it and he will not last forever with my behavior. I couldn’t figure out my problem as I have always been the happy, fun drunk! well, July 4th was my worst strange behavior….I drank as I normally do. It’s was late and dark one moment I am kissing my hubby on our boat, the next I am yelling at him to go back to the cabin.. I was so mad at him I jumped off the boat and got my legs on the boat and somehow broke both of my feet!!!! It is January and I am finally in regular shoes. this morning I googled this subject and read soma posts to my husband and now that we both know the problem, I will never get drunk again while I am on this medicine. Thank you everyone for posting your stories…

January 2, 2012 at 6:18 pm
(345) Jane says:

I’ve been on 300 mg Wellbutrin for a long time now and absolutely cannot drink without consequences. I don’t tend to crave it and the few times I have, it’s turned out badly. Major headaches, blurred vision, extreme agitation and mood swings for about 2 days after. I felt completely out of control and considered checking myself into the psych dept at the hosital. I didn’t however because I was too embarressed about letting others know how I was feeling, so instead, I stayed inside figuratively and literally until the symptoms wore off.

January 6, 2012 at 6:52 am
(346) chris says:

I was on wellbutrin for smoking cessation. In college i could drink a good deal and would feel the effects and usually remember my evenings.

Drinking on wellbutrin is entirely different for me. I dont feel the effects of the drinks im having which leads me to drink more. Then its like someone flips a switch and i stop remembering entirely. This happened after my companys christmas party (luckily my girlfriend got me to leave before i was an ass). It happened on new years again and i was aggressive for no reason. I missed 2.5 hours of the night and almost drank myself to death. 2 day hangover and i was even physically aggressive and still drunk the next morning. Not good. Dont drink if youre taking wellbutrin. Or quit both even.

January 6, 2012 at 3:28 pm
(347) Dave says:

I’ve been on Wellbutrin XL for just over a year now, and I was able to drink occasionally as long as I didn’t have more than a couple of pints. I might feel a little off the next day, but nothing major or lasting.

That changed on New Years Eve. I definitely over did it, and I’m still feeling the effects a week later. I have been really depressed for the first time since I started taking the Wellbutrin, and it has been pretty rough.

Reading some of the comments here has given me hope that it will pass. I just have to ride it out, I guess.

January 15, 2012 at 3:07 am
(348) mel222 says:

I’m so glad I found this. I’ve been on wellbutrin for 2 months. In the past I was always the girl that could handle her liquor. Always taking care of my wasted friends no matter how wasted I was. It use to take a lot to get me drunk. And I always had the ability to know when to stop. Now on wellbutrin I get drunk supr fast. I become emotional, irrational,and violent. I don’t know when to stop drinking. Iwake up th next morning and I can’t remember most of the night. I am 22 years old. Started drinking at 14 (young I know). Never in my 8 years of drinking did I ever black out while drinking. I also wae up with the worst hangovers. Takes me two days to recover. It’s affectnig my relationshipsand my reputation. Now I am the crazy drunk girl.I’ve learned m lesson. Moderation doesn’t work for me. Unfortunately I’m just gonna have to give up drinking all together.

January 29, 2012 at 12:18 am
(349) ammie says:

I’m on my 4th beer now and feel nothing. I take 450 wellbutrin XL After reading these posts though it has me nervous, but I guess not enough to dump the last half of my beer out.

January 30, 2012 at 6:28 pm
(350) mike says:

I’ve been on genetic Wellbutrin (bupropion) for about 7 or 8 months. when I first started it, it was for anxiety and to quit smoking. It hasn’t helped the anxiety at all but I did quit smoking…for the most part. You have to be ready to quit. Anyhow, I have never been a blackout drinker. But I do love a good beer. I have drank tons of high alcohol beers with no problem. I mean I might feel a little fuzzy the next day but it’s never been anything it off the ordinary…

February 9, 2012 at 10:05 pm
(351) Emily says:

I was taking Wellburtin XL 300mg for about 4 years. I was in college during these four years. I drank heavily and smoked some pot and never felt anything bad from the Wellburtin. I’ve been heavily medicated for severe depression and psychosis since I was 13, so maybe I don’t know any different.
Anyway, I had to go on Wellburtin’s long lost sister drug, Aplenzin because my insurance was forcing me to take generic Wellburtin which didn’t work for me.
Same deal. I drink pretty regurally and all I feel is a hangover the next day.
Maybe I’m just lucky, maybe I’m used to all the drugs being pumped in my body. I take three different antidepressants and antipsychotics. Maybe it’s the perfect Molotov cocktail for enjoyable drinking!

February 12, 2012 at 8:19 pm
(352) Teresa says:

Like everyone else, I wish I would have found this website before this weekend. I was taking 150mg of generic WB for a couple of weeks and drank a few times with friends and had no problems. I went up to 300mg last week and had a blackout episode on Saturday night. I went out with the girls for a bachelorette party. I had no clue that I shouldn’t drink while on this med (the Dr. didn’t mention it, there is no warning sticker on my bottle, and I’m stupid for not reading up).
Anyway, I have two glasses of wine w/ dinner, two rum and cokes at the hotel after dinner, then one rum and coke at the bar. Normally this wouldn’t cause me any problem. I would barely be buzzed, but I didn’t remember half the night and my friends told me that I seemed sober one minute then, bam, totally wasted the next. Like other people, I had bruises all over me the next morning, and some guy wanted to take me home. Thank goodness for my girlfriends! Luckily, I was not mean or violent, just embarassed that I could have ruined the bride’s night. The next morning we were all talking about how drunk I was when I said, “It’s like I’d been roofied!” Then we all went “ah-ha! It’s the WB.” I’ve spent the last hour reading every post on this website and I can definitley see a pattern. I love to social drink, but I’m going to stop, especially at the upcoming wedding of my friend. I do not want to make a fool out of myself in front of all of my friends. Since I’ve only been on the meds for a few weeks, I can’t tell if it’s doing me any good or not. I’ll give it a couple of months, but I have to admit that it will be so weird going to weddings, b-day dinners, and concerts without drinking! But, I’ll still do that over blacking out and losing friends, so…

February 14, 2012 at 10:43 pm
(353) Tom says:

Wow, I’ve read just 20 or 30 comments, and I can’t believe how similar my experiences were with alcohol while on Wellbutrin to others’ experiences. I stopped drinking completely almost 2 years ago, and it has made a huge difference. I was puzzled why sometimes I would get very drunk on just 2 or 3 glasses (and sometimes more) of wine, and then I’d have to face several days of feeling depressed. I also found that after 1 or 2 glasses of wine, my “off switch” didn’t always function. As a result, I’d end up drinking more than I planned.

I didn’t really connect the two; instead, I narrowed down that I wasn’t an alcoholic but rather an occasional binge drinker. Both are serious problems, but binge drinking is much much easier to deal with. That’s when I realized that I really just needed to give up alcohol altogether. While I still believe that to be true, I now better understand how Wellbutrin just added to the problem. I will have one sip just to taste someone’s wine, but I stop at that and never have more than one or two sips (or usually none at all) over the course of an evening.

Thanks for all the comments…I wish I had found this much earlier. Best of luck to all.

February 26, 2012 at 5:29 pm
(354) Kat says:

Hi Everyone–
I have been taking Wellbutrin 300mg for about six years for a completely different reason than most of these posts– low sex drive. I donít smoke and do not have depression or anxiety; I was going through menopause and my sex drive was really lacking, and I wanted to fix it. My doc prescribed the Well to treat it because increased libido was a known positive side effect of the drug. He asked about my alcohol consumption and I told him that I drank wine almost every night; not to treat myself for depression, just to decompress from major stress at work. He told me to limit the wine to two glasses while on the Well, but that didnít do much to help me to relax, so I went back to my usual amount. My friends and family told me that sometimes I would say things while drinking that I didnít remember the next day. Also, I would be happily partying along hardly feeling anything, then all at onceóbam– I would ďhit a wallĒ and I was done for the night and had to be put to bed. This happened on and off ever since Iíve been on the Well but I never connected the passing out to the drug/alcohol interaction.
I recently got a huge wake-up call; I was drinking wine with a friend on her boat and we walked up to the public restroom. The last thing I remembered was waking up on the floor of the restroom with my friend wiping blood off of my face. I had passed out while washing my hands and hit my head/face/nose on the sink. Good thing my friend was there to pick up the pieces and get me back to the boat. I was hurting for the next three weeks and have a scar to show for it, but it could have been so much worse. Thanks to all of your shared experiences I put it together, and now the Well is out of the medicine cabinet, out of my life, and into a box under the sink. My doctor switched me to a cream for the hormone imbalance. I am now able to continue to enjoy my wine in a safe manner without having to worry about suddenly passing out. (p1)

February 26, 2012 at 5:30 pm
(355) Kat says:

(p2) So, I made the decision to drop the drug and was lucky to find a better/safer way to solve my health issue. Sure, I could have kicked the wine to the curb and kept on taking the Well, but I wouldnít have been very happy with that. Some people might say that my wine use is a crutch to deal with my work related stress, but after reading a ton of these posts it seems like most of us are just trying to do the best that we can with what we haveÖ we all need to evaluate our own situations and make informed decisions.
My conclusion from my experiences: Whatever your reason for taking Wellbutrin, be VERY careful if you are going to drink even a Small amount of alcohol; if you are going to continue to drink, inform your family and friends so that they will keep an eye on you and know how to help if you have ďan episode.Ē Bottom lineÖ alcohol + Wellbutrin is a crap shoot, my friends.

February 26, 2012 at 11:33 pm
(356) Brenda says:

Thanks for all the post they have helped me a lot. I had more than usual
amount of drinks on friday and ever since then i have felt so bad. I just started Wellbutrin 100mg 2 x a day not yet a week ago. Wasnt feeling to bad until i drank. Now i know why. Going to watch that from now on and might have to stop my wine.

March 1, 2012 at 2:59 pm
(357) Adam says:

Great posts.. I actually just took my first 50mg pill today, I have been on Prozac for 20 years. I asked my shrink for a pill that would help me loose some weight and limit my drinking. love my cocktails. After reading everyones comments, I will just have a puff of a joint, but will refrain from the booze.

March 6, 2012 at 11:21 am
(358) Phil says:

1 drink before bed + 150 mg bupropion = next morning hangover. Happened twice now. Never a problem for 10 years.

March 7, 2012 at 10:43 pm
(359) Angie says:

I’m taking 300xl for about a month now. I went out with my friend, had a couple drinks and a couple of shots. I was feeling good. It did impair my judgement, ended up making out with some guy and then his other friend tried to jump in. Somehow, I got super woman power, got them off me and ran outta there. I then proceeded to almost get into a fist fight with my best friend and I am not the violent type. I physically threw myself to the pavement trying to give myself a concussion. I kept telling my friend I wondered if I would be intubated with a miller or a Macintosh blade. When she got me home, I started having very suicidal thoughts. I took some antianxiety medication and went to sleep.

March 9, 2012 at 9:38 am
(360) Leea says:

I started my first dose this morning of 150 mL and will be upping it to 300 mL in a few weeks. There’s a birthday party this weekend that I was going to consider having one, maybe two drinks. Not worth it! I’ll find an excuse to not drink and stick with energy drinks instead! Thank you for all the stories!

March 9, 2012 at 3:59 pm
(361) Noah Pearce says:

Please don’t take this statement for encouragement but I have never had a problem with drinking and rebound depression or any side effects on Wellbutrin. This may be in part because of the med combo I’m on, which also includes a benzo and severely limits the amount of alcohol intake.

I have PKD and a natural occurance with the disease is elivated heart rate. My doctor started me on Wellbutrin after adding the 3rd blood pressure medication. I still take a shot or two when my heart rate elievates past a safe benchmark to help slow it down. I don’t get drunk. I don’t even really get relaxed. I merely avoid long term hypertension.

March 10, 2012 at 1:49 pm
(362) Jo says:

Same thing happens to me. I’m on 150 mgs. I’m only 31 and I want to be able to have fun with my friends, which sometimes includes drinking, I don’t get buzzed as quickly as I used to, but I do limit myself to 4 mixed drinks while I’m out. The next day that follows, like freaking clock work, I’m over emotional, suicidal thoughts,I hate myself. I don’t want to move, my depression is so intensified. This is the second time it’s happened since I’ve been on wellbutrin. I feel better knowing that this isn’t just me experiencing this. So not fair, I just want to live life normally.

March 17, 2012 at 1:07 pm
(363) sher says:

im so glad i just found this site. i have only been on wellbutrin for about 2 weeks now. last friday a friend and i went out and had some beers. i wasnt aware that you were not suppose to drink on this stuff!! i wacked out!! i dont remember hardly anything from the nite, bits and pieces here and there, but i was drunker than hell!! i guess i was talking about crazy things!! my boyfriend, whom i got in an agrument w/that night ended up breaking up w/me. it was my fault because i didnt want to tell him that i was on a/d’s. i was so embarressed. needless to say, im going to talk w/him monday and show him this site!! i am no longer drinking!! id rather be the “real” me.

March 19, 2012 at 12:05 pm
(364) Courtney says:

Finding and reading this blog/site is unbelievably validating. I’m on 300mg of wellbutrin and I seriously almost had the cops called on my by my own boyfriend Saturday because I was SO out of it. I was triggered losing my wallet and had a panic attack that turned into rage. I have never in my life been a violent drunk or even just a bad one but after reading others who’ve had extremely similar experiences, it all makes sense. I also had no idea alcohol and wellbutrin can cause seizures….wow. I don’t think the benefits are outweighing the consequences anymore, I’m going to taper starting today.

April 3, 2012 at 11:34 am
(365) Phoenix says:

Wow…I have never had a side effect..I’m on 300 XL daily and I can drink and everything. No nausea, vomiting or fatigue. Maybe it’s the effects of taking Wellbutrin with other medications and then on top of that drinking? What does everyone think?

April 8, 2012 at 1:37 pm
(366) Allison says:

I’m so glad I found this. I am taking Wellbutrin 150mg a day and lastnight I went out drinking. I was drinking excessively which is not good but I had a horrible experience. The combination brought on a depressive episode out of nowhere that was very intense. I have not had an episode like that in years. I felt like I had no control over it. It took me awhile to get out of it. This morning I still felt drunk and I have been having cloudy thoughts and dizziness, feeling like I might faint. It resembles the feeling of ur equilibrium being off balance. It is bazaar. I have learned my lesson. I will be laying off the alcohol it is not worth it. I do not want to go through that again. If you are going to drink while taking Wellbutrin do not drink excessively and be careful!

April 16, 2012 at 1:56 am
(367) Maya says:

I have been on Wellbutrin for several months and noticed that, after I have few glasses of wine or champagne, I wake up in middle of night feeling like a complete failure. Feelings of deep shame, guilt and embarrsament are so strong that I have to coach myself out of it trying to remember things I could be proud of. My self-esteem has never been strong but Wellbutrin + three glasses of wine combination seem to totally kill any spark of self-acceptance. In fact, it is 2 am now and I had some champagne last night… silly me.

April 19, 2012 at 3:31 pm
(368) Alex says:

Reading all of these comments has made me realize how depressed I’ve been since drinking with Wellbutrin. Come to think of it, before I discovered that wellbutrin and alcohol have led me to this depressed, uncommunicative slump, I have drank every night with it up to the point of my realization. I suppose it’s because the combination feels great when you’re drinking, then doesn’t work out as well the next day.

That being said I also emote with the psychotic experiences portion of things because when I’d drink on Wellbutrin I would almost be manic; like I didn’t give a shit at all. For example: one night, I had quite a few drinks with my Wellbutrin (9 in total and I weigh 126). My friend was complaining that she didn’t care for how she looked in her pajamas and she was embarrassed about it. Without a second thought, I ripped my pants off and threw them down the hallway asking, “Do you feel better now?” I also stole her friends hat off his head, and proceeded to wear it for the next two hours; having met him an hour prior.

In short, I think the fact that for some this combination is pretty fun, which is why I was doing it. However, there’s no denying one becomes a little crazy with this mixture and the day after just isn’t worth it. I’m just glad I figured this out before things got too crazy.

April 22, 2012 at 1:15 pm
(369) Elizabeth says:

I’ve found that I can’t even tolerate one drink while being on Wellbutrin. I’m on 200mg / day and 20mg Prozac for anxiety. After just one glass of white wine with a big dinner I get depressed for days – crying, low self esteem, want to stay in bed all day… It’s not worth it. I feel so much more like myself when I’m out with friends and NOT drinking.

My only advice to anyone who’s on WB is to see how it affects you in a completely safe environment with someone you trust before trying to drink socially/in public.

April 27, 2012 at 8:41 am
(370) Kelly says:

I’ve been prescribed Welbutrin ER 150mg for a few months and I don’t have any problem with drinking. We drink pretty regularly (3-4 times a week) and I haven’t noticed a change in my tolerance at all.

I have heard that alcohol completely cancels out the effects of welbutrin anyway (definitely true for prozac… might as well have not been taking it for all I was drinking), but strangely my psychiatrist told me drinking wouldn’t make a difference on the effect of the medicine. Strange. Maybe it’s beause my dose is semi low.

April 30, 2012 at 1:17 pm
(371) Courtney says:

I think it really depends on the person. I have been on 450mg of wellbutrin for the past few months. I am in college and get pretty trashed occasionally. I haven’t noticed an increased effect of alcohol or abnormal behavior. Hangovers are not at all worse for me, actually last time I drank heavily I woke up the next morning full of energy and tried to drag my hungover friends out of bed.
The fact that alcohol lowers the seizure threshold freaks me out a little so I am going to back off the drinking a little, but so far I have been completely fine drinking heavily. I have a very high tolerance for alcohol so I suggest you know how alcohol effects you before taking the medication and adjust the amount you drink accordingly.

May 1, 2012 at 9:48 pm
(372) DoNotRemember_0412 says:

I have had some serious issues with Wellbutrin and alcohol. I do not recommend it. I have taken it for about 6 years and it helps [along with exercise, diet, therapy, using common sense] with Chronic Major Depression that is actually pretty bad. I have blacked out a few times on this drug and done and said highly inappropriate, out of character, caustic and abusive things I do not even remember a shred of. Friends filled me in later as to what I said, did, broke that were loyal enough to kindly explain the mean, distasteful and horrendous jackassery my brain came up with and threw at people that did not deserve inaccurate, designed to be mean projections. I am not a lashing out at people person. I am a peaceful people. Whatever this drug does if you are not in a happy, comfortable place and are considering downing alcohol [more than one glass of wine, perhaps 2], if you need filters to deal with things in your past or current when you are in any kind of uncomfortable situation – do not even think of combining these things if you are of sound mind. I don’t even want to recollect things I said and did that were so horrible were beyond the point of forgiveness and were things I would erase out of disgust even while in a total rage writing in a private journal to vent. Conclusion of my experience:
Wellbutrin + more than 2 servings of Alcohol = Bat S41+, Mel Gibson, Brittney Spears Craziness.

Don’t combine unless you want to hurt people that you would not hurt, even if you don’t particularly like them.
Who loves everyone? Besides customer service. [kidding]

May 2, 2012 at 2:27 pm
(373) DanielBrazil says:

I have been on 150mg of Wellbutrin daily, for the past 2 months…

Throughout this Labor Day long weekend (I took a 4-day holiday), I had 8 beers on Sunday and some champagne (5 glasses) last night…

On Sunday night I felt anxious at the party…I was aggressive and rude to my friends and also felt depressed and rejected by everyone.

I left the party crying like a baby….went home and ate a lot of ice cream, just like a teenage girl….(shameful)

I’ve been feeling like shit since then….very depressed, anxious about my long distance relationship……paranoid about cheating etc…that’s not common for me….I am obsessed and anxious…

After last night’s champagne drinking I went home very agitated but nothing negative happened…

Today I am feeling down….anxious, depressed….negative thought all day long……..and before drinking I was having 2 full months of REAL IMPROVEMENT on my depression and anxiety….


May 8, 2012 at 5:09 pm
(374) Juan says:

Hey, I’ve been on the Wellbutrin for nearly one month. Last week I was invited to a party and I was so scared because of the posts I had read here, especially the one by that girl who woke up on the beach with a rat in her hand – haha, that was so freaking crazy! So I just thought I would only drink one or two beers. I ended up drinking 2 liters beer and about 6 mixed drinks. It all went amazingly fine, I didn’t feel the sluggishness which is quite normal after such an intake, but pretty much the opposite: I was really drunk but fully awake and energetic at the same time. No problems at all the morning after. If you’re in doubt about drinking while on the Wellbutrin, just start drinking slowly so you can actually tell the difference. I’d suggest you take a benzo the morning after anyway, as this can minimize the risk of seizures.

Have a good binge everyone!

May 9, 2012 at 3:05 pm
(375) gingercat says:

this thread is actually hilarious and some comments do seem like having been posted for exactely this purpose(beeing amusing I mean). The guy who got his girlfriend pregnant etc. Well, i laughted my head off because some comments seem so absurd in my current state. oh, by the way did I mention I’m drunk while taking welbutin and ok, i can rely to the anxiety problem. And maybe my judgement is clouded a bit…;-)
So, this is the live experience after 3 glasses of wine. Feel free to comment!

Please DO excuse my english, I’m not a native speaker…

May 9, 2012 at 3:13 pm
(376) gingercat says:

@ Juan
Does alcohol really increase the risk of having seizures? after all it provokes a release of GABA… Is the dopamin the reason for the seizures?

May 11, 2012 at 9:15 am
(377) LES says:

I do not recommend drinking alcohol while taking wellburtin but I do it sometimes. I drank a 12 pack of beer and I have been on 150ml for about 1 week and a half. It didn’t really bother me much, but I feel much better when I am not drinking. You have to make a choice, either be depressed for a couple of hours of partying, or be happy and miss out on all the fun? I am glad I am taking wellburtin, because I have been binge drinking for years now and I really don’t feel the need to. I think this drug and help some people shake alcohol addiction.

May 21, 2012 at 3:10 pm
(378) laurie says:

I’ve been on the generic of WB (Bupropion) 150 mg for just 3 days. What’s weird is the doctor prescribed it when I told her I’d been drinking excessively to cope with stuff at work and home. She said she’d prescribe something that wouldn’t cause problems if I did drink occassionally! Then I read an article on line that said if you drink a lot, you could encounter seizures if you totally quit when you start taking the drug! My goal is to quit drinking altogether, but I certainly don’t want to start having seizures!!

I’m confused!!

May 24, 2012 at 6:06 pm
(379) Faith says:

i agree…….. It leaves you depressed and total black outs…..

May 26, 2012 at 2:57 pm
(380) Tawnia says:

I came to this site looking for answers because my son is currently sitting in the county jail on felony charges for trying to kill his sister-to which he has NO recollection. Come to find out he had been recently prescribed Wellbutrin for anxiety & ADHD. What has me VERY upset is prior to this, he was an inpatient at a mental health facility & they KNEW he had a drug & alcohol problem yet prescribed him the medication anyway knowing the potential side effects. Some of you may joke but there is nothing funny about it. Wellbutrin & alcohol do NOT mix & my family is paying the price. What upsets me even more is the mental health facility is claiming that the Wellbutrin had nothing to do with the psychotic episode my son experienced but after reading many of the above comments, I now know that it isn’t true. I believe more than anything now that it had EVERYTHING to do with what happened.

June 3, 2012 at 3:07 pm
(381) Stephanie says:

I have been taking Wellbutrin XL 150mg for a little over a year and I have never had a problem with alcohol. If anything, it increases my tolerance and ability to rebound without a hang over. The only thing that I noticed after 4 days in cancun drinking was that I was tired for a few days after getting home, but that could have been from the flight.

June 5, 2012 at 7:24 pm
(382) Aaron says:

Most of these experiences are very accurate. I’m taking 300mg per day and it has completely changed my life since I started 1 year ago. I may add the total depression and self loathing I feel for 2-3 days post binging is really horrible. I also have experienced the black outs and getting “weirdo” when drinking on Wellbutrin. It’s really scary and hopefully soon I can quit drinking altogether. Stay away from red wine!!!!!!!! Good luck everyone!

June 12, 2012 at 9:23 am
(383) RockCandy3418 says:

I needed to verify what I thought was happening the day or two after having a drink or two while taking bupropion, which are feelings of moderate to severe depressive moods. It’s definitely not worth negating the improvement and suffering through the decreased self esteem and productivity. Thanks to everyone for sharing!

June 19, 2012 at 11:44 am
(384) Nicole says:

Thank you all, now I understand why I cannot stop crying for the last 24 hours. And after just a glass of wine!

June 22, 2012 at 11:44 am
(385) kenny powers says:

Huh, I find this very interesting. Clearly it depends on the individual b/c i’ve been drinking fairly heavily lately on 100mg Wellbutrin + 40mg Prozac, and I don’t notice the effects being any different or enhanced. If anything I’m even more of a happy drunk that usual.

Obviously it’s not for your depression to drink to excess, but I have to say my next day hangovers (or 2-3 day recovery periods) are not nearly as bad as they were before adding Wellbutrin to the mix. I used to get really down on myself and in a funk, flooded with regret and shame…now I bounce back really quickly. I take it easy and hydrate all day and then by the following morning I’m ready for an intense, early morning workout and could be ready for more drinks that night.

Anyway, not trying to encourage people to act as i do, it’s definitely not the healthiest thing…i guess I’ve just been good lately about changing my frame of mind and not taking myself or things too seriously. Just having a ton of fun. Helps that I’m in the early stages of dating a girl i’m totally crazy about. If you’ve had bad experiences or get out of control when you drink (Wellbutrin or not), then yes you might want to cut way back. But I’ve personally always been a goofy funny social drunk, and it actually gets me out of my reserved shell and leads to some great times and new friendships i never would have made if i hadn’t gone out for drinks.

just my $0.02

June 22, 2012 at 7:42 pm
(386) anonymous says:

I have enjoyed drinking for a number of years but have been dealing with depression since I was 9 years old. I realized the effects of mixing with the drug are double of what you would typically feel without taking it. Overall I am feeling nuch better after 2 months as it has taken the edge off off my anger and I was conservative with drinking at first but once I was more immune to it I had been able to handle the alchohol intake better. Maybe not a good thing but I am writing this to contribute to a scientific evaluation of someone who has a high tolerance for alcohol. I have to admit I still enjoy the alcohol buzz and probably not a good candidate for this drug. I do feel down for a short time and the alcohol really take a lot of my energy and motivation away. I am still struggling getting my act together and I know I need to if I want to get to a better place in my life. I thank God for keeping me alive as each day is a blessing. I hope my message to other drinkers that this may not be the best way to go. I am just blessed I am still living to place this comment.

June 30, 2012 at 6:20 pm
(387) Brandi says:

I’m very glad that I came across this thread. I drank last night on Wellbutrin at a party and was psychotic acting…. it was Jekyll and Hyde. All of my friends and my husband were seriously confused about what was happening. Today I feel like shit b/c I acted like a complete idiot. I hope that my friends will be able to understand what happened.

July 2, 2012 at 11:57 am
(388) don says:

Amazing thread.

I dated a 48 year old doctor for 18 months who is diagnosed with dysthymia and takes 150 XL. She was prone to rages and crying spells, just generally labile, and had significant interpersonal issues at work for many years. She has never married even though she is attractive, smart and funny.

She likes to drink and gets sexually disinhibited with only a few drinks. The psychologist I spoke to, however, dismissed the idea that the WB/alcohol mix caused the sexually impulsive behavior. But I’m not so sure – she did some outrageous things while drinking, things you wouldnt expect to see a middle-aged physician with a reputattion to keep doing in public. Her rages quieted down when drinking, in fact, she calls herself ‘the kissing girl’ when she drinks. Too flirty, slightly combative if crossed for hitting on married men, reverts to child-like demeanor.

So im wondering if anyone else has any experience with this kind of behavior w/WB and -OH. it was very disruptive to our relationship.

July 13, 2012 at 8:41 pm
(389) Seems says:

Ive been takin 150 mg of the extended release stuff for about a month and a half and I feel amazing also I ten to drink a minimum of two beers a day and really it’s been a life changer my life has never been better

July 16, 2012 at 1:17 am
(390) anonymous says:

DO NOT DRINK WHILE ON THIS MEDICATION!!! The effects I’ve recently experienced were so unhealthy. I usually can drink three bottles of wine (if I do drink) and still walk the straight line. However, while on this medication, I had black-outs, weird behavior, severe alcohol withdrawal next day after just 2-3 drinks!!! I wasn’t drinking for almost a month when I started this medication, but after I resumed alcohol consumption effects it had on me were horrible. I do feel better regarding my depression and anxiety symptoms…so the medication is helping. But be careful when mixing this and alcohol!

July 31, 2012 at 2:05 pm
(391) Traci says:

Ive been on Wellbutrin 450mg for over a year.. it has definitely helped me with depression.. but i have to say that I am also an alcoholic.. Sober for 9 months!! BUT when I drank.. (I would drink ALOT.. like a 1/5 of vodka and a couple bottles of wine and still wanting more on a normal night). When I would wake up after nights like that, I was in the deepest, most painful depression and that ALWAYS lasted for 3 days and still felt bad on the 4th & 5th day as well. I would also puke ALL DAY the entire day after and sometimes on the 2nd day. Now that I am sober, the wellbutrin xl is working great and I could kick myself for what I was doing to myself. I HIGHLY recommend to never drink alcohol & take wellbutrin.. or for that matter, any anti-depressants. Even if I had a few (2-3 drinks) I would have the darkness and exhaustion… Just another opinion to consider :)

August 5, 2012 at 10:14 am
(392) Evan says:

Ive been prescribed Wellbutrin 150 2 times a day for at least 4 years but never took it regularly until recently. With me being in college I tend to drink often and this was the first time i had done so on the meds. I got drunk incredibly quick after a few beers and blacked out within the next hour the next day i woke up with one off the worst hangovers i ever had. i was vomiting to the point of dry heaving blood and went to the E.R for several hours. im so grateful that i found this thread!!!

August 6, 2012 at 7:40 pm
(393) Mae says:

I took my first 150mg xl today. I am used to drinking roughly 8 Budweiser over the span of 12 hours a day. So for me my concern is not only how will the Wellbutrin affect me, but the sudden and dramatic stop in drinking I have researched, is not good for anyone. So I’m in Limbo. I don’t want to do more harm than good in either direction. My goal is to stop smoking and dramatically reduce my alcohol consumption. Anyone else have issues or experiences with this kind of a situation?

August 6, 2012 at 10:13 pm
(394) bryan says:

DO NOT DRINK WHILE TAKING ZYBAN…i am in the u.s army and i am trying to quite smoking. My doctor prescribe me zyban and didn’t say anything about drinking. I was taking 300mg a day, a few nights ago i started to drink heavily but nothing out of the ordinaly for me. I woke up the next day not remembering anything….when i woke up i felt like i did something horrible. My wife was gone and the dog, my friends said that my wife dropped me off for a cookout was there for like a hour and i freaked out on the neighbors a women pulled out a knife, i tried to fight everyone was punched in the face, broke my wifes windshield and said horrible things and was threating her and just plain not making sense. The people i was with are people i deployed with and would do anything for and wife means the world to me. I almost lost my wife other this, and i am to afraid to take the zyban even not drinking on the med. I hope this helps someone out there because if it wasnt for this site i couldnt show my wife similiar experiences. This was by far the worst blackout i ever exprienced even after before told and seeing recording i still can remember and for me extreme anger and crazy attitude DO NOT DRINK ON ZYBAN!!

August 14, 2012 at 12:17 am
(395) Rachel says:

I firmly believe that Wellbutrin is super dangerous when mixed with alcohol. I need to face this fact so I won’t keep believing I can really stay in control any more in “binge drinking environments” such as this party after a wedding wherein which I had been reunited with old college friends, igniting an old college kind of party time which I can certainly NOT participate in anymore (nor should I have ever, really). It just seems so weirdly normal at the time, to binge drink out of excitement or celebration… I “forget” in these stressful social situations. Particularly if you are emotionally unstable like I am, it is a horrible idea to mix these two… I ended up getting black out drunk in my hotel that night; I was crying and I don’t remember very well, but I was so distraught and my judgement so bad that I let this random girl who found me crying in the hotel “help me” (even though I remember asking her to leave me alone several times) and in doing so, she led me to a toy cop who handcuffed me and slammed me on the floor… he ended up being in the wrong with his supervisor (being very drunk and emotional is not a crime…) But I certainly feel like I subjected myself to a kind of police brutality due to my own foolish lack of forethought regarding the bad things that can happen when I’m that messed up… I feel so ashamed and horrible that I treated myself so “badly” as to allow that to happen, even though it was this security officer that was really in the wrong… there was no reason for him to have used violence against me… Anyway, this horrible situation has prompted me to stop drinking altogether. I have had a couple bad incidences when I used to go to bars alone (cuz I liked to deny my own vulnerability)… but this is really the last straw. I don’t like booze THAT much to deal with even one drinking related crisis a year. I already have problems with PTS symptoms… I should avoid trauma at all costs. Sigh :/

August 16, 2012 at 4:01 pm
(396) M says:

I have also had problems with drinking while on Wellbutrin XL. It made very, very irate. I’ve never had that problem with just alcohol alone. This i was before i knew not to mix the two.

August 19, 2012 at 11:44 am
(397) Qwik says:

Drinking on the drug does pose a problem. It’s almost like an amplifier for the alcohol. I drink once or twice a week. It does lead to a blackout if too much is taken in!

August 21, 2012 at 8:43 pm
(398) Brody L. says:

Drinking 1-2 drinks is probably alright. But if your saying you can drink several without feeling out of control etc. Then your more then likely acting crazy and ust don’t realize it due to the fact that the Wellbutrin is binding to your dopamine receptors and the alcohol is releasing and reuptaking it along with serotonin.

I’m a Neuro Science major and wellbutrin(bupropion) + alcohol = trouble eventually.

August 22, 2012 at 9:23 pm
(399) Ash says:

I’ve been on wellbutrin for only 2 weeks (100mg twice a day). My Dr put me on it to help quit smoking. So the other night my boyfriend and I had some friends over and I drank prob around 6 beers. I felt fine… at first. We decided to go out to the club around midnight or so. Drinking a couple more beers at the club..still felt fine, a little tipsy. After we went to an “after hours” club and had some more beers. By the time we walked outside.. my memory is blank. I totally black out. I couldnt tell you how we got home, who drove, how we got in the house. Nothing. All I remember is laying in my bed. but when I woke up the next day, I was on the couch. Needless to say, I wont be drinking on wellbutrin anymore. Totally freaked me out.

August 22, 2012 at 9:25 pm
(400) Ash says:

I should prob add, im a pretty heavy drinker. All in all I only drank about 8 beers that night.

August 27, 2012 at 5:24 pm
(401) M says:

The comment in the first post, “I went ape shit,” aptly describes my husband’s behavior on New Year’s Eve a couple of years ago when he mixed wellbutrin and alcohol. We came home and he saw that the kitchen was messy he went nuts. He grabbed dirty dishes and anything else he could get his hands own, and put them in the garage (didn’t throw them, thank goodness), yelling the whole time. This went on for about an hour. It was not like him at all. Usually he gets cheerful when he drinks a little too much.

He was not on it for depression, but to help stop smoking. He tried it again last fall and he was angry all the time, whether he had a drink or not didn’t make a difference. I cried for an hour one time and wondered if we were headed for divorce. I thought about all the good times we used to have and it finally dawned on me that this was not the real him. I told him he needed to stop wellbutrin or go to marriage counseling with me. Once he stopped, I had my husband back! I wonder if these side effects happen to people who don’t need it for depression.

September 11, 2012 at 10:08 am
(402) Aaron says:

I actually had something similar to the people above with the opposite effect. I was able to drink almost 20 beers in one day and never even felt drunk! I didn’t even notice how many I had until I had gotten home and thought about it. Same with a few other occasions, two bottles of wine. Still functional, still aware. I’ve never drank that much ever. The next day I felt really dizzy and out of it, not really hungover in a regular sense, just strange. This is definitely not good to drink this much.

September 15, 2012 at 1:26 am
(403) Chelsey says:

Does anybody know if it will make a difference if I am regularly taking the medication, but skip a dose when I plan on drinking that night?

I am also a college student and enjoy drinking on the weekend. I’m not quite at the stage in my life where I’m ready to give it up, either.

September 19, 2012 at 11:21 pm
(404) Shirley says:

Why is it that rehab centers and physicians prescribe wellbutrin to individuals when they are discharged from treatment. With knowing the relapse rate for alcoholism is so high, and the dangers of mixing alcohol with wellbutrin, isn’t this just an accident waiting to happen? I agree Wellbutrin is a great medication if used appropriately, however, an alcoholic is not someone in control of their life. They don’t believe alcohol will kill them, so they are most likely not going to believe the warnings on the prescribtion bottle. Wellbutrin does not curve the craving for alcohol, it just makes you sick if you drink while taking it. On the other hand, studies have shown Naltrexon (sp?) does curve the cravings but is not prescribed as often nor is antabuse prescribed as often. Just Wondering.

September 25, 2012 at 1:41 pm
(405) Don Merganser says:

I’ve been on Wellbutrin for about two months. I’m a moderate to heavy drinker. 4-5 bottles of brandy a week. I have noticed outrageous violent tendencies that I never had before. I’m not certain if this is due to the fact that my wife was having an affair (why I’m on 150mg a day to begin with) or if I have yet to address why my wife began cheating. Iíve been consuming alcohol in those quantities for years socially and never have I had violent tendencies.
My Dr. knows of my passion for French libations.
Is drinking this much dangerous while on it?

September 28, 2012 at 12:26 pm
(406) Brit says:

I have only been on 150mg of Wellbutrin for a week. My dr did not tell me to avoid alcohol even though I told her I tend to drink more than I should on the weekends. Last night, went out with my boyfriend. After 2 beers any filter I had was completely gone. Told him everything he’s ever done to piss me off. Continued drinking. Long story short when we got home I broke the glass out of s huge picture frame, broke a mirror, cut myself badly and did not care at all. Basically had a psychotic episode or something. It was very scary and I feel awful :( Wellbutrin and alcohol DO NOT MIX!!

October 11, 2012 at 1:54 am
(407) cancan says:

Been taking Welbutrin (generic 150 1/day) for about a month now. I drink regularly and have noticed that while on the meds I get very irritable, depressed, and anxious. I hold my breath and feel like i’m suffocating. Then get scared I will die. I’m thinking about quitting alcohol all together, because of how it makes me feel. I feel more depressed and out of control when I drink. I want to be happy not depressed so I am going to stop drinking.

October 12, 2012 at 8:19 am
(408) Phil says:

Hello I am 52 yo male.
I was glad to find this site during my search for wellbutrin side effects. I am on 150 mg dose also. I was off this medication for about 8 months but prior to that was on it for several years. I recently went back on this medication about 4 weeks ago. I find myself getting more agitated and angry after I have had several beers. I am seeing a wonderful woman and feel like I am turning into a monster at times after going back on wellbutrin. Then I am depressed the next few days. I find my self being irrational and impulse. Last night was the tip of the iceberg I walked out on this wonderful woman at a local sports bar. I have never done this before to anyone. Does this sound familiar to anyone else on Wellbutrin

November 2, 2012 at 12:24 am
(409) RA says:

I wondered why Wellbutrin SR said not to drink while taking this medication and now I know why. I would blackout after having only 3 drinks. I drove one night thinking I was fine because I knew how much I drank but the next day I couldn’t remember driving at all. Like many other people who have posted I also felt very, very depressed for a few days after that night of drinking. I’m going to avoid alcohol from now on.

November 3, 2012 at 9:24 am
(410) sara says:

wellbutrin and alcohol are absolutely horrid together.

I wake up the next morning feeling shakey, dizzy, nauseous, my anxiety sky rockets. I feel no motivation whatsoever and get spurratic waves of sadness for no reason. Drinking is definitely not worth having if your going to feel this way the next morning.

For people in college like me, I have found that I make a lot of friends by telling them I will be their designated driver. That way I can go out and not have to deal with people pressuring me to drink. Everyone respects a good DD!

November 7, 2012 at 10:34 am
(411) Karyn says:

I had the same horrifying experience as Kevin. I had 2 glasses of wine with dinner and totally blacked out, left the house without anyone’s knowledge and was in some neighborhood bar for 4 hours. Totally unlike me, and very scary. I woke up at home in the morning, thank goodness, but I had bumps, bruises, and cuts all over me as if I army crawled all the way home. I will stay away from alcohol while on this medication

November 10, 2012 at 8:08 pm
(412) anon says:

I am 17 and have been on wellbutrin xl for 2 months as well as zoloft. It has helped me so much and I am doing a lot better, no more anxiety attacks, episodes of depression that last days, and I can actually get to school. I stopped drinking as soon as I went into treatment, I used to binge drink a lot before. I have started drinking a little lately and last night I got pretty trashed (more than I intended) but I woke up this morning with not even a bad hangover! I dont feel depressed and I feel fine physically. I know this is contrary to what everyone has said but I thought I would share because the past few times I’ve drank it’s been fine. Maybe it’s because I’m young or I drank a lot of water or whatever. I am still going to be really careful though!

November 25, 2012 at 7:40 pm
(413) Brendan says:

My problem wasn’t suicidal/depressed behavior as much as projectile vomit was. Man, when I was on wellbutrin I painted the town brown off of 2 glasses of wine.

November 28, 2012 at 7:13 pm
(414) Tiff says:

I’m glad I found this information. I have a drink or two once in awhile but a couple of weeks ago I went out with some friends and had more than a couple. It made me feel great-I was talkative and outgoing. The next morning I got a huge hangover and was vomiting–something I haven’t done in years. Ever since then I feel like I’m starting over with bupropion. I feel like I did before taking it. I think it will start working again slowly but drinking one night isn’t worth the next few weeks of depression!

December 1, 2012 at 1:56 pm
(415) Christine Dufour says:

It’s been almost 9 months since I start Wellbutrin. It is incredibly conforting to see that i’m not alone. If I drink more than 2 alcohol drink, I feel depressed for two to three days, my vision became blury. So after 5 or 6 episodes, I now know that drinking alcohol dosen’t worth this pain.

December 8, 2012 at 11:05 pm
(416) Kim says:

I’ve been taking Wellbutrin since I was 9 (I’m 18 now) and did not start drinking until I was 16. I have never felt any bad side effects from taking my 200mg and drinking later on.

December 24, 2012 at 4:19 pm
(417) alison says:

i’ve been on a generic of wellbutrin for a few weeks now and its helped me from slipping into a massive depression but hasnt really gotten me up out of the low base background mood. im warry of taking anti-depressants so im concerned about the effects since this is the only one i’ve been on. i recently have been drinking on the weekends and have been getting very drunk very quickly but its usually a happy drunk but im dizzy and stumble a lot and last night i felt like i was going to pass out after 3 beers which would normally just get me buzzed. there are a number of factors in this like i stopped drinking as much in the last 4 months so my tolerance may have gone down, but im not experiencing any other things being described like black outs or weird behavior or a abnormally bad hangover. this is just how its effecting me and i wanted to share in case someone else had the same thing going

December 25, 2012 at 9:24 pm
(418) Michael says:

Glad I found this string. It’s Christmas and I was thinking about having red wine with dinner. I’ve been on 150mg of generic Wellbutrin for a little over 2 weeks. I tend to abuse alcohol (drink to get drunk) so I’m going to pass on the glass of wine. It just doesn’t sound worth the risk.

The temptation goes back in the bottle.

Happy New Year!

January 2, 2013 at 4:33 pm
(419) Paul says:

JUst started Wellbutrin 2 months ago. I am a heavy wine drinker as well and did not want to give up my wine. Wine = happiness :-) though my MD warned of the side effects of using both, I disregarded the advice and did my own thing. By the 2nd day I was on Wellbutrin I noticed immediately my happy ME come back. I have not limited or discontinued my wine, and it has had zero effect on me. Wellbutrin in the morning and wine in the evening. Never felt better:-)

January 3, 2013 at 6:09 pm
(420) Laura says:

I wish I had found this string before New Year’s eve :(
It is now the 3rd of Jan and I’m still feeling really really bad after drinking about 5 wines and 4 champagnes on NYE.
I’m on 150mg XR a day and normally I take it in the morning but during the holidays around 1pm.
The first two wines I felt nothing, I was at a party out of town and couldn’t wait to get to my own city to party on. I got too confident about drinking, I even opened a champagne bottle on my own and took it with me in the street. I have been a big drinker in the past, but since about 5 years I can’t take much alcohol anymore.
I didn’t blackout until I walked back home (don’t remember the route and don’t remember coming home/going to sleep), but I did act strange in the bar. I cried when my friend was talking to me and later I spoke to several people, each time completely ignoring the person I had just spoken too. I felt confident and spoke to everybody in the pub, which I normally wouldn’t have done.
It wasn’t even a good night and I upset my friend, who went home and I stayed on my own in the bar for I guess hours I don’t remember. I would never do that normally.
The worst feeling is the days after, anxious, depressed, I’m even scared of touching knives, I’m very insecure, I feel guilty for wasting these days, I should get some things done but I can’t. Tomorrow I have to work again, not sure if I can. I am a smart person and run my own business but I feel like a stupid irresponsible idiot now.
I feel like how I used to feel after drinking binges of days. The whole reason to take WB is to stop feeling so bad. I really hope life before this terrible night will come back, because I was actually doing really well on WB, it has worked miracles for me, and I will stop drinking alcohol full-stop because this is not worth it at all and I want to continue taking WB.

January 16, 2013 at 11:18 am
(421) Stephanie Smith says:

It;s not to offten i drink alcohol, it would be nice to have a drink once in a while!! I’m not sure about depression feeling worse but i do know my heart racing and feeling like i can’t breath. I have been taking this for over a year and i’m having lots of bad dreams every night and the main reason for taking this drug is to quit smoking.

I think it is time to stop taking this drug, it would be nice to sleep well and have nice dreams again.

January 23, 2013 at 8:15 pm
(422) Chris says:

wow…I was searching for some sort of answer…I have been on Wellbutrin to stop smoking and last night I blacked out after only 4 drinks…my girfriend took me home and I guess I became verbally abusive and violent. I am not that guy…I don’t remember anything at all, it was total lights out. I am glad I found this thread to show her that it wasn’t me, it was like I was possessed. I feel terrible that I hurt our relationship with the things I said and did, luckily I didn’t hurt her…this is the real deal! Scary shit!!!!

January 29, 2013 at 7:56 pm
(423) May says:

There are so many experiences here that I can relate to – but nothing comes close to the crazy things I have done when I’ve mixed Wellbutrin with alcohol. I take 300mg a day.
I have not been very good at avoiding alcohol.

After two glasses (wine seems to be worse than everything else) the word ‘unstoppable’ is the best way to describe me. I guess the good part is – I don’t become violent, or hurtful to anyone else in a physical or psychologically abusive way.

My problem is the opposite – I become extremely sexually aggressive and fearless and hell bent on getting with someone. The AD booze mix makes me a total nymphomaniac! In my mind, I really am having a lot of fun at the time, but the hangover the next day – you can imagine the unique form of shame-based depression I feel.

I keep drinking, and finding my way from one bar or party to another (sometimes alone! …but I’m so outgoing and fearless on the mix, it doesn’t take me long to make friends) and I always end up sleeping with people I wouldn’t have otherwise. I’ve even gone to a sex club (which isn’t inherently bad) but in my city its a reckless thing to do.

And yes – I’m in a relationship, and although we give each other a lot of freedom, he doesn’t know the half of it.

So I go through periods where I’m careful not to drink too much, or be around my boyfriend or home where I can’t get into too much trouble.
I get bad and good in phases – I travel constantly for work and so have plenty of opportunity to drink (work functions) and then recklessly sleep with people. It is definitely a massive side effect for me. My doctor hasn’t warned me about mixing Wellbutrin with alcohol, and didn’t take much notice when I told her how reckless sexually I am on the drug.

anyways, I write this because although I’m able to talk about most of it with my boyfriend, its good to write it down somewhere, and also I wonder if anyone else has experienced it.

February 9, 2013 at 9:28 am
(424) qpwo says:

Oh my. I am a 52 year old female that has been on 300 mg Welbutrin for 10 years. It has been very effective…until recently. I have wondered if it was hormones (no menapause yet), been on the meds too long, major work related stress, .etc. I just put it all together. My diet has changed drastically to the “clean” style and I have lost 10 pounds. I do everything I can to be healthy. Within the last few months I started drinking an occasional glass of wine. I had not drank anything since I was in my 20′s. Lately I have been feeling horrible. Just a glass every couple of nights, but I have been extremely depressed, agitated, one evening thought I was going to have a nervous breakdown! I believe it is connected and I found this site for a reason. I am going to completely quit my red wine and see what happens. I might even need to reduce to 150mg, who knows? I have never wanted to drink due to so much alcholism in the family. It may be a combintion of many things, but this is a good place to start. I wish the best for the rest of you. Depression is a horrible thing that no one understands unless they deal with it. Bless you all.

February 13, 2013 at 11:22 am
(425) Affiong says:

i am on W 150mg with celexa 40mg. yesterday i drank 5 margaritas at my favorite restaurant and still felt mentally sober but physically drunk. fast forward 3 hours later – i am with my bestfriend in the basement and i am crying because someone is controlling my brain. for the next hour, i cried some more and lamented the loss of my touch with reality.
im not sure what to think or do.

February 14, 2013 at 2:01 am
(426) josefulano says:

I’m so thankful for this thread. I’ve been on and off Wellbutrin for 8 years. Inevitably it has “stopped working” and I begin to feel more and more depressed as if the drug has no effect on my depression any more.

Now that I connect the dots, it is obviously connected to my (moderate) red wine consumption. Absolutely without a doubt my mood darkens in the days after drinking and the wellbutrin seems to do no good.

I can’t believe that I’ve been chasing around with my psych all sorts of different medications when the one that works best, wellbutrin was most likely being short-circuited by my drinking. So obvious!

February 15, 2013 at 1:08 pm
(427) Bobby says:

I take wellbutrin xl 300mg and seroquel 300 mg. I wasn’t sure if the effects of the alcohol were reacting with the wellbutrin or the seroquel. Can anyone relate to this? The next day after having only a few drinks the night before and Getting a slight buzz, today my head seems cloudy, fuzzy and I feel frustrated. I get these momentary sensation of depression anxiety and frustration. I’ve been doing so well with my bipolar 2 diagnosis and these Meds have really made a difference. Do you guys think the alcohol + wellbutrin could affect me mentally and emotionally?

March 1, 2013 at 8:09 am
(428) Polo says:

I take wellbutrin xl 300mg and seroquel 300 mg. I wasnít sure if the effects of the alcohol were reacting with the wellbutrin or the seroquel. Can anyone relate to this?
Both are; wellbutrin is a cathinone (like Bath salts) so you can intensify the effect of alcohol with it and easily go into blackouts and aggressive behaviior.
Seroquel is a dopamine blocker so it will intensify your craving and restlessness for drugs/alcohol.

The next day after having only a few drinks the night before and Getting a slight buzz, today my head seems cloudy, fuzzy and I feel frustrated. I get these momentary sensation of depression anxiety and frustration. Iíve been doing so well with my bipolar 2 diagnosis and these Meds have really made a difference. Do you guys think the alcohol + wellbutrin could affect me mentally and emotionally?

Yes, also physically.
If you are really bipolar remember that drinking can make you look exactly like a Bipolar depression. is your doctor aware opf your drinking? Let him know.

March 20, 2013 at 11:43 pm
(429) Jon says:

I’ve been taking 150mg of Wellbutrin for 2 months now to treat symptoms of ADD. As a college student I drink pretty frequently, several days a week, and recently recently I have found that I can’t drink as much as I used to, or when I do drink as much as before I get extremely drunk very quickly, I guess the key for me is moderation, this forum was eye opening in that respect.

March 22, 2013 at 1:59 pm
(430) John SLC says:

I am really glad I checked this out. These comments have been very useful.. I have been on Wellbutrin 300 XL for a little over two years and never touched any alcohol while on it.. Until now. Under lot of stress I thought hey a little wine won’t hurt. The first time I had one of the worst hangovers I’ve ever had, but I thought Hmmm must be a cold or something. Did it a second time and my depression really hit me hard. I thought well it is winter and with SAD and all I was blaming that – now after reading the comments I know it is the combination of alcohol and the wellbutrim. So no more alcohol for me. Thanks and take care.

March 26, 2013 at 6:36 am
(431) Justin says:

This is all insane..I came here to see if anyone else had the issue of deppresion I am feeling. I had a couple beers friday night then a couple drinks of rum saturday and sunday night. I only had a couple as I learned the hard way about mixing alchol and wellbutrin My story is much the same as most people have already mentioned. I figured this time all would be fine if I only had a couple drinks, Well since having a cople drinks I have been right back in my depression feel like doing nothing can’t get anything done mood. I can’t beleive there is this kind of effect. I have been so happy with this medication. It has made me feel fantastic. I am gald to have found this site with so many people having the same issue. It lets me know all will be back to normal and also teaches me the price of having even a couple drinks.

April 10, 2013 at 3:32 am
(432) Steve says:

you people are hopeless. Instead of taking something to help you get better you end up drinking alchohol. which it says on the damn label ‘do not drink alchohol’ you people are so slow -.-

April 17, 2013 at 1:43 am
(433) SillyMek says:

Never drink with Wellbutrin!! I had two mixed drinks, and went from happy to the worse case of depression I have ever experienced! It took a few days to regulate my emotions… Horrible, horrible experience! Alsi do not go days without it. I am suffering from wooshing headaches, insomnia, and crying spells off and on..job, so… Lost my insurance :( $108 for sanity and I am broke….

April 17, 2013 at 12:16 pm
(434) Katrina says:

I didn’t read through every comment here (there’s a lot!), but I’ll give my perspective to those that may be out there like me. I believe that my depression has been a result of years of alcoholism..(consuming a depressant and feeling disappointed in myself). Of course, most of us alcoholics don’t tell our Dr the whole truth about our quantity of drinking, and I seem very normal (functioning alcoholic) so she prescribed Welbutrin for me. It really helped me to cope with my days but I still drank at night, every night. I never felt some of what you all said; feeling bad for days, acting bizarre, getting drunk faster, etc. However, I’ve recently been looking at my drinking and realizing that black outs have become a part of my nights…and it all began around the time I started taking this. Long story short, I’m on my 4th day sober, trying to make some positive changes which hopefully will result in not needing the meds…but I’m thinking my blackouts are from that concoction…not good.

April 17, 2013 at 3:30 pm
(435) ADR says:

I am so glad I found this forum when I did. I started a low dose of Wellbutrin for smoking cessation and didn’t think too much about it. After a couple months I started having psychotic, drunken, outbursts toward my boyfriend with little to no provocation. They would carry into the next day and eventually would happen at any time. My anger was completely uncontrollable and violent. He was starting to believe I was just a crazy psycho and was ready to jump ship. After a “rage”, I would be more myself and convince him I wouldn’t do it again. He said he couldn’t get through to me at all, nor did he see me in my eyes. I had my last tantrum over something I believed to be true and, even after I found out the truth, couldn’t calm myself down. I had packed his belongings in 20 minutes and kicked him out of our home. He had nowhere to go and I didn’t give him a chance to think about it. He packed it all up and found someone to take him in. After I had calmed down, I realized I had destroyed our home and made the biggest mistake of my life. We were both devastated and I felt horrible. After calling a therapist because I thought I was losing my mind and was ready to diagnose myself with a severe mental disorder, I found this forum. I want to thank you all for sharing your stories because this forum is the only reason he is even giving me a chance to get better and move forward. He also found out about another person he knew who had similar experiences. Looking back I realize I experienced a lot of side effects that I didn’t take note of at the time. After only a few days without it, I feel myself coming back. I see now how powerful that drug is and do not recommend anyone using it for smoking cessation. It is not worth the side effects and damage to personal relationships, especially the one with yourself. I’m thankful I figured out the connection when I did and before it was absolutely too late to repair our relationship.

April 24, 2013 at 12:06 am
(436) Financial Advisor says:

I have been off and on Wellbutrin for over 5 years now. I started when I was in banking to help with stress headaches from mean customers. The Buproprion helped me shut off my mirror neurons and not soak in as many problems. My headaches went away as I upped to the 300 XL. With drinking I also noticed that my words came out in different order some times or muffled. Also my short term memory doesn’t work and I will ask the same questions right after I hear the answer. My body seems to metabolize alcohol a lot slower too. I’ve noticed that some times I don’t feel drunk but still have no memory the next day. Lately my ears won’t stop ringing and my heart seems to have an irregular beat. I am tryingto cut down on alcohol as well but it is difficult with the group of friends I have.

Currently, I am taking the buproprion hcl 150mg 12hr SA tab. When I drink I get the shakes real bad the next morning. I am only 33 but I feel like I’m 80 when this happens. A small price to pay to fight depression and social anxiety I guess.

I have experienced the puppet like state that some have mentioned above. When I drink and look in the mirror it seems like am looking at someone else. I choose to stay away from mirrors because I hate the way I look. Almost disappointed in myself when I drink.

I guess I just wanted to let everyone know you are not alone. The VA actually gave me a 30% disability rating stating it might have been due to PTSD after my time in Afghanistan.

Who knows, I make it work and when I get super depressed I am good at telling myself it is only chemical and I will be fine in a couple days. I have found meditation to be helpful in changing my mood. A reminder app helps. This is coming from a white boy Iowan who doesn’t believe in most religions… Try new things and stay strong. Thanks for the thread :)

April 24, 2013 at 9:07 pm
(437) Dolan says:

I am quite a heavy drinker, and have received legal consequences (MIP, DUI, Wrecked cars) due to my alcohol consumption, about six months ago I was prescribed Wellbutrin and have drank a few times on the same days as taking a pill of it, and thus far have experienced no apparent problems. However, I never drink to excess while actively on it in fear that things could go very wrong. Just want to let you heavy drinkers/alcoholics who are prescribed this drug know that it is possible to drink while taking it, just be careful!

April 26, 2013 at 10:10 pm
(438) lisa says:

My question is ,, Does anyone experience heart palpitations or a heavy feeling in your chest while drinking and taking wellbutrin? I also have graves and over active thyroid ..the heart palipitations only happen when I drink. Or having anxiety attack. Just started wellbutrin n ptu for thyroid. Nott liking this heavy pounding feeling in my chest while drinking , kinda scary..is this just a side effect from mixing alcoholic n wellbutrin?

April 29, 2013 at 9:42 am
(439) Hannah says:

I’ve been on Wellbutrin for about a year and a half. Last spring (a year ago), I had a violent episode with my husband while drinking a lot one night – I threw all of the shoes in my closet at him. I am not a violent person. You’d think I would have learned by that…Hubby and I like to have a drink or 2 on a nightly basis. This is an off and on trend for us. Although I have not had another violent outburst like that, I have noticed lately that I’m depressed to the point where I’m either almost crying or crying if I’ve been drinking for a couple of nights (and when I say drinking, I’m only talking about a drink or 2). How do you think I happened upon this thread? Well, because I knew somehow that there must be a correlation, and when I typed in “Wellbutrin and Alcohol,” this popped up. I’m seriously thinking about laying off the sauce completely. MAYBE will have a glass of wine or champagne on special occasions. Someone above has it absolutely right – the joy you experience while drinking for an hour or 3 is not worth the depression you feel for a few days afterward.

April 30, 2013 at 1:02 pm
(440) Betty says:

I have just completed week 4 being on 300 mg XL. I’m still waiting for it to fully kick in. I am still having crying spells & feeling blah, not wanting to do anything. I do drink every night, so I’m beginning to wonder if that is keeping the meds from working. I haven’t experienced any other side effects of drinking while taking Wellbutrin, like the crazy acting or hangover feeling. I sure hope I will feel the full effects of this soon…..it gets pretty difficult waiting!

May 18, 2013 at 11:51 am
(441) Faith says:

I am so glad to have found this page and read so many of your comments! I have only been on welbutrin for a little under 6 months, and what’s ironic about my situation is I had just been telling my boyfriend that I can’t drink anymore because of my medications. I wanted to be cautious, especially since I’m so young. Well, for some reason last night it didn’t occur to me to NOT drink, or at least drink without the desire to get a little drunk. I had a mixed drink of vodka and sprite. In total, it was maybe. 3 shots worth of vodka in 3 separate drinks. Well, the reason I stopped and didn’t get anywhere near finishing the 4th drink was because my stomach slowly started to hurt. It wasn’t horrible, just uncomfortable. Then it clicked, and I got worried, so I went online to find answers. The stomach discomfort is the only thing I’ve experienced so far, and it makes me nervous, but I’m also a bit relieved now. So thank you everyone!

May 28, 2013 at 4:22 pm
(442) gui_felix says:

I just started taking Wellbutrin XL 4 days ago.
I know that the effects happens by extended-release.It means that now I don’t have much substance in my body, and drink is not a problem ,right?
So when I get some weeks of treatment, my body will have accumulated these substances and then could be dangerous interact alcohol & drug ?
When Wellbutrin XL makes its good effects and when is dangerous to drink? thx

June 1, 2013 at 3:14 am
(443) Jake says:

Stumbled across this page because I went out last night and had a couple of glasses of red wine and got violently ill; worse than I have ever been on or off alcohol. Sorry if this description is a bit graphic, but I think it’s best that other people on Wellbutrin (I’m on 300) read stuff like this so they don’t make the same mistakes.

I threw up until there was nothing left to throw up, then threw up bile until my stomach was completely empty, I was then basically like a cat trying to cough up a hairball. The vomiting reflex was there but nothing came out, it was horrible and lasted for maybe 2-3 hours. I passed out with a tingly sensation over my body thinking that I should maybe call an ambulance. When I woke I could barely walk and, liked described by some of the other people here, developed twitches in some of my muscles. When I got home went into a deep sleep from which I awoke surprisingly early feeling terrible.

I’ve never reacted this badly to alcohol, and have consumed far greater amounts before (I had maybe 3 or 4 glasses of wine). So far the next day I’ve had splitting headaches (almost like permanent brain freeze), still occasional twitches, and basically the worst hangover that I’ve ever had. No amount of water or electrolytes seems to help and the only food I can stomach is yogurt.

The symptoms I’m experiencing are ridiculous considering the amount of alcohol consumed and is definitely related to the Wellbutrin XL 300mg, which I started taking a week ago. The two don’t mix. If you’re going to drink be very conservative and have maybe 1 or 2 at most with food. I won’t make this mistake again and got the fright of my life.

June 5, 2013 at 11:24 pm
(444) Tish says:

I’m on a very low dose of the Wellbutrin and I only have a glass of wine (sometimes only half a glass) maybe once a week. I find that the next day or a few days later, I am very irritable and want to go off on everybody for the smallest things. I don’t know how this is gonna work being on this stuff. I dont really want to give up a glass of wine every now and then. Maybe there’s something else.

June 10, 2013 at 3:43 pm
(445) Leslie says:

So glad to have found this thread! I am on wellbutrin and after three glasses of wine taken with a huge meal, I got incredibly drunk–crying, angry, and I can’t even remember most of the evening. I am so glad not to be the only one who has had a similar experience. No more alcohol while on this (or any other) anti-depressant. SO not worth it!!

June 28, 2013 at 11:44 am
(446) melanie says:

Not only did it make me really depressed; I blacked out from mixing the two! Very bad out come! I thought there was something wrong with me , I was suicidal and more depressed than ever. I could not figure out why than it dawned on me I never drank that much on wellbutrin before…..

July 3, 2013 at 10:16 pm
(447) Panther9 says:

After a week on 150 mg SL, I had 3 glasses of wine last night and no dinner (except a banana). Did not feel drunk and even went to gym at 8 pm. Today, really bad hangover. Physically all my normal hangover symptoms–very tired, bad stomach, GERD. Also felt very depressed later in the day. And had complete memory loss of two phone calls I made last night while sipping on the 2nd glass of wine. (When the people I called returned my calls this morning, I was surprised and it took me a few seconds to understand why they were calling.)

I am not going to drink anymore. I really felt good on W until now. I need this medicine to work, and giving up my 2 glasses of wine is something I’ve wanted to do anyway.

Good luck to all — be smart and safe.

July 9, 2013 at 10:37 pm
(448) Cel-Well says:

Wow. Don’t want to repeat what everyone else has said but I am thrilled I found this! Was about to give up on W after two weeks but clearly booze has been messing it all up.
I started W about 2-3 weeks ago. I went out drinking the first week and drank way more than I have been able to in 20 yrs. Didn’t even feel drunk or tired late at night after about 10 drinks, very strange for me. (Don’t recall any hangover either, also shocking). But on the way home I started crying and couldn’t stop, eventually crying myself to sleep 2 hrs later. I figured it was because a friend died recently. Also I noticed the next day I couldn’t remember parts of the evening, but wasn’t worried about it.
I was actually thrilled I could drink again since 10 yrs of Celexa made drinking hell – severe headaches with even one drink and hangovers from hell. So I usually smoke pot instead of drinking. But i ran out of weed a few days ago so I had a rum and juice. I was fine, and didn’t even want more than one but the next day I was more depressed than ever, ridiculously irritable and freaking out on my husband and kids every 5 minutes. Sometimes screaming in rage. And the suicidal thoughts were overwhelming.
But I didn’t make the connection until I drank again the next night and following day was hell again. Then I went googling about W two-weeks-in to see if I should stick it out or quit, when I found this. I stayed up til 3am reading these 447 posts.
I cannot continue abusing my family and riding this roller coaster so booze will have to go.
Not going back to pot yet either, should probably just let the the meds do their thing for awhile before making any decisions about switching.

July 16, 2013 at 10:40 pm
(449) Jim says:

I’ve been on 300mg for about 4 months. I drink beer every day playing bar trivia. Never had an episode like in the posts. The wellbutrin has had a very positive on my smoking, as I’m down at least 30%. Don’t know how much the effectiveness has been reduced.

September 19, 2013 at 8:01 pm
(450) Lulu BS says:

Thank you one and all for writing your experiences here. I am quite sure you just saved me from making a big mistake.

September 21, 2013 at 11:08 pm
(451) Tara says:

Wine and liquor can be an especially horrible mix with Wellbutrin. I was on 300 mg about 9 years ago after my son’s birth to treat pp depression. Had good results until my husband took me out on the town when my son was about 6 months old. Ended up with several free shots at an upscale restaurant bar, had another drink I believe and then became triggered by something my husband said to me about being rude to another female who had taken my seat at the bar. It was as if I became instantly possessed and saw red. (Never had become physical with anyone let alone my husband who is 6ft 4in.) I remember bringing both of my hands to his face and clawed him deep enough to where his face bled. The night was a total nightmare. One of the worst in our marriage. I became a different person. Fast forward 8 or so years and I’ve been back on W for about two months. Have had a drink here and there but last night went to dinner with friends and had three small glasses of white wine within about a hour and a half and was absolutely wasted. Had a bad confrontation with husband when we got home not as bad as before but still potentially violent. Have felt so hungover today. Very sleepy. I believe I will forgo any kind of alcohol again. The view is no longer worth the climb.

September 30, 2013 at 6:45 pm
(452) mark says:

Yes. I take SR and everything I’ve read here has been extremely helpful. If I have more than a few beers, I become easily agitated and emotionally callused in otherwise normal situations.

I will feel anxiety and above all, a self-righteous kind of arrogance.

It’s good to be aware of how your own body reacts to this cocktail of chemicals in your brain. Be careful with any drugs you put in your body and certainly make sure you’re paying attention to behavior patterns that might come about with drinking and antidepressants.

Also- If i’m even an hour or two off with my timing w/ these meds, it can send me into a similar funk.

October 13, 2013 at 7:55 am
(453) Cindy says:

Omg. I’m on day 11 on 150mg wellbutrin xl. I literally had 1 milk stout. I was beyond depressed and had make anxiety the next day, and still abit today! On top of that I now have a cold. The depression was so bad, I was sent home from work because I couldn’t stop crying. I know now to avoid alcohol all together because my body clearly can’t take even one drink on this medication!

October 17, 2013 at 5:39 pm
(454) Ashle2 says:

Has anyone tried to just skip their dose fr the day they plan on drinking? I was on 100 x2 for about a month, upped to 150 x2 on teh 4th of this month..I am having a huge date day with my husband tomorrow & wine will be involved. I’ve drank twice on it so far, but only when I was taking the 200..I’m wondering if I’ll be ok if I cut my dose to 200 for the day, or just take the 1 150 in the am…if that makes any sense?

Sorry if this has been asked before, didnt make it thru all the comments

October 17, 2013 at 5:41 pm
(455) Ashley says:

ps- I am on the generic..it doesnt say SR or XL so I’m assuming I’m on the regular dose? I’m 24, female, 120..the last two times I drank I did end up downing the bottle & not gonna lie..it’ll probably happen again this weekend.. thanks!

October 25, 2013 at 5:42 am
(456) Olivia says:

Right now i’m on 150mg once a day. I’m in college, so I used to drink a lot socially and pretty safely and never had any bad effects. However, one night I must have not drank enough water and for the next two weeks i had severe depression and panic attacks that slowly went away after a month. I would not recommend having more than two, or three drinks if you’re hydrating and eating well.

November 6, 2013 at 10:20 am
(457) Terry Hunt says:

Hi all, seems to me you are all coping with zyban (or at least getting some benefit from it). I was prescribed zyban 4 years ago, i was a heavy drinker and was not advised that this could be a problem. one week in i had a massive seizure remaining unconsious for several minutes. i called the nhs hotline and was advised not to continue taking the zyban. i soon fell into a deep depresion from which i am still suffering. i have been to hell and back. i know dose myself up with 100mg 5htp daily which takes the edge off. if anyone has a possible remedy for this it would be gratefully received. my advise to anyone about to start a course is dont do it, your sanity is worth more than your smoking habit.

November 16, 2013 at 4:20 am
(458) Belgian dude says:

I’m taking 100mg Sertraline since 1,5 year and extra on it 300mg Wellbutrin since 4 months ’cause I still got more depressed than before. Since taking Sertraline, I was able and willing to drink more units than I did in the past and NOT feeling hungover at all the day after (while I always was in the past with a lot more), but my memory wasn’t always that clear. Since I’m combining this with Wellbutrin, I was even able to drink a lot more units, still not feeling hungover at all the day after, and people hardly notice that I’m drunk, but my actions got more extreme, criminal or even unfriendly towards woman, while I hardly knew anything of it next day. While the evenings itself, it kinda gives you an effect like speed should do (never done that though), the days after I had cloudy, paranoid thoughts (’cause you know only little parts f.e. being thrown out of a club, but why????), it made me more unsure, etcÖ I decided to stop drinking alcohol now, ’cause that friendship got too close or familiar. Though I’m already cutting down on Sertraline and Wellbutrin, I’m not sure if I’ll ever drink again while taking this medication. I just know it starts with one or two unites, but after a few months I’d probably be drinking a lot more again, and would probably be suffering from that ‘friendship’ again…

December 27, 2013 at 12:48 pm
(459) Don't Drink says:

I must share my horrific story. Iíve been on Wellbutrin for about 2 1/2 months. I have a few drinks since I started here and there but have had no ill effects of being on Wellbutrin. However, on Christmas Eve, just a few days ago I drank a lot more than normal, was having a great time, noticed I was a lot drunker than I should of been. My family hosted Christmas and after everyone left a simple conversation with my husband turned into complete hysteria for no reason. Heís a police officer and after he went to bed I went into his safe and took out his gun and contemplated my life. THIS IS NOT SOMETHING IíVE EVER THOUGHT ABOUT. Iím not a suicidal person, the thought never crossed my mind. After sitting in fetal position on the floor for an hour I put his gun back and went and told him I was suicidal and put his gun in my mouth (which wasn’t true) and that our family might be better off without me. I canít stress enough that this is just not me. It was like an out of body experience. Iím so FREAKED out as is he and I can’t blame him. I didnít realize how dangerous it can be to drink.

In addition, I completely blacked out putting gifts under tree from Santa, etc. I wasnít even that depressed when I went on Wellbutrin, I heard good things that Wellbutrin was a good pick me up and you can loose weight with it. I threw out my pills, so done with that. Going to go a holistic route with diet and meditation. Just be aware. I think I seriously damaged my marriage with this. I keep telling him it was the Wellbutrin too much booze combo, but not sure he believes me. What a nightmare. I totally ruined our Christmas.

Please please please heed my warning and be careful combining the two. Weíve been together for 15 years and this type of hysteria has never happened, ever. I’m just sick over this, can’t get the ugly scene out of my head.

January 7, 2014 at 8:57 pm
(460) TJ says:

Wow, I read almost all the posts here, thanks everyone….I’m a 53 year old female and a nightly drinker, several beers and 2 or more tall jack on the rocks every night (I work in bars, so I routinely do this after work.) I rarely get hangovers, just the draggy feeling that coffee gets rid of. I am on day three of 150 mg Wellbutrin Sr. , to help me quit smoking by avoiding the depression I get every time I try to quit. This morning when I woke up I felt I was still drunk and my head and thoughts were super cloudy and distressed. I had a lunch date and had to keep putting it off coz I couldn’t get my chit together at all! It accelerated, my face and chest were flushed and hot, vertigo was there ( I am prone to that already) and my coordination was off – everything I’m reading above. At lunch I was weird, claustrophobic in the booth, not finishing sentences properly, searching for a word..like..bobby pin lol. I snapped self-righteously at my friend and on and on. It’s 9pm now and I think I’m recovering a bit. It was a miserable day which is why I ended up here, seeking information. I hope I can NOT drink, but 2 beers max would probably be ok. Thanks again for keeping this forum going, I’ll be checking back!

January 9, 2014 at 9:18 pm
(461) Nathan says:

Just wanted to be the one voice out there saying that those effects only occur in certain people under certain circumstances. I was previously a very heavy drinker, now I only drink every couple of months. Started Wellbutrin a month ago, and had 8 shots of vodka and a few of some mango rum, last night with no side effects. I was never affected by hangovers or leftover alcohol side effects though, so this might just be for me.
All in all, I just wanna throw out there that you’re not gonna have a seizure if you drink on wellbutrin. Alcohol increases the chance of side effects, but does not necessarily trigger them. If you have a history of seizures/fainting/blacking out then I wouldn’t recommend getting plastered.

January 13, 2014 at 10:54 pm
(462) shannon says:

I’ve been on wellbutrin for 2mos now -switched from escitalopram which was making my anxiety and depression more severe — and funny thing is i drink more on the wellbutrin than i ever did in my life. About 1-2 glasses of sparkling wine a day. I’ve had no side effects whatsoever, however i’m wondering if the drinking ITSELF is a side effect. previously, I might have 1 bottle worth of wine/alcohol in a YEAR…now i’m going thru a bottle in 2-3 days. but i’ve had no wacky behavior, blackouts, dizziness, hangovers, seizures at all. i’m also well over 250lbs, so maybe the amt of alcohol i’m drinking is not enough of a factor.

January 28, 2014 at 11:19 am
(463) Kris says:

I have been on Wellbutrin XL, 150 mg, for less than a week. I tried to drink my usual two beers at a local brewery and ended up aggressive, irritable and bitchy, taking it out on my poor boyfriend. I only recall bits and pieces of the entire night. Very unlike me. I won’t be drinking on this med again. Too dangerous.

January 29, 2014 at 4:57 pm
(464) John says:

I have been taking Wellbutrin or Wellbutrin XL in varying doses for several years and I have never experienced any increased negative effects of drinking. Then again, I am not a binge drinker and I rarely have more than 2 to 3 drinks on any given night. I suppose if you’re going to go on a bender, you can expect that to interact badly with whatever meds you’re on.

February 9, 2014 at 3:50 am
(465) rosieposey says:

I had no idea this medicine was known for causing blackouts and lowered tolerance to alcohol. finding this thread had given me comfort knowing i am not alone. i’ve been a social drinker for years…work m-f and usually just have some fun on the weekends. i had noticed that the alcohol was affecting me differently but because of the black outs i just thought i was drinking more than usual. i thought i needed to go to aa. all day long i’ve been beating myself up and crying and just miserable with shame and guilt. last night i blacked out and almost assaulted someone. usually i am a happy drunk and always remember everything. now i know i have to stop completely. thanks to all of you for sharing your stories. hearing from another person that you did such awful things and then not even remembering is just so awful. also i would like to say i have been on prozac, paxil, cymbalta, lexapro, and celexa and i have never experienced this alcohol hulk syndrome before. however, welbutrin is the only one i feel that works for me. it’s going to be tough to quit drinking. any suggestions?

February 9, 2014 at 3:53 am
(466) roseyposey says:

also, i have experienced blurry vision and just thought i needed an eye exam. i feel so stupid that i didn’t put this together sooner. i also get the red blotchy skin around my chest and neck when drinking.

February 24, 2014 at 12:26 am
(467) tabacofree says:

Soo…. I just started taking Bupropion a lil over a week ago to quit smoking…Wow it works well. I went from a pack and a half a day to 5 cigarettes a day first two days and now tabacco free for 5 days now.. I scared the hell out of my wife after we had a night out and I drank what normally would leave me a lil tipsy but good..Boy was I wrong…. I was informed by my wife the next day that she woke up because she heard me in the bathroom…. when she went in I was standing in the bath tub speaking jiberish and opening and closing a bottle of body wash…. We’ve been married for years and never had this kinda behavior happen,.

March 11, 2014 at 3:42 pm
(468) Kelly says:

I have been on bupropion (generic) for 8 years. I rarely drank when I started, but I have gradually increased over the last 5 years to 5 – 10 drinks daily, more like 15 on the weekends. I’ve realized I’m not really getting drunk as much as I’m feeling euphoric and energetic (after 10 drinks I am drunk). That’s not what getting drunk felt like in college before I was on Wellbutrin. I am 5’4″ 130 lb female. I do find that I start to black out after 6 drinks or have missing pieces to my evening. I used to figure 1 hour per drink to sober up, but now I find that even after 8 hours of sleep I still have a buzz when I wake up. I get the chills/sweats and a flushed face as I sober up, but rarely a headache, never vomiting, very slight nausea. I believe this is because alcohol and wellbutrin compete for the same liver enzyme in order to be processed. After taking Wellbutrin regularly the drug has already decreased the availability of that enzyme so it takes your body longer to process alcohol. I have only found one place stating this so I can’t vouch for its accuracy, but it explains what I am experiencing. I have tried AA, but at about # 3 I get the euphoria and there’s no stopping me. I also have tremors the following day, which I attribute to alcohol withdrawal. I thought I turned into an alcoholic, but I haven’t been severely depressed in years, I have a successful career and I work out regularly so I didn’t see a problem. I am now getting my liver enzymes tested and tapering off bupropion. The ideal solution would be to quit drinking, but that’s not realistic. I think once the euphoria is gone, cutting back will be much easier. Hoping I don’t spiral in into depression by going off bupropion, but I need to save my liver. Anyone found a successful alternative AD after having Bupropion work but quitting it?

March 16, 2014 at 11:02 pm
(469) Mike says:

I’ve been taking wellbutrin for months now and have found no adverse affects other than one time someone continuously handed me glasses of wine. I had the equivalent of more than a bottle and a half of wine probably and it definately left me feeling cloudy for a couple of days. I had no intention of drinking like that and I almost never do, and haven’t since I’ve been on the medication. No blackouts though. Maybe a bad headache but I get headaches from a TBI so who knows. I am a big guy, I will say. I am about 5 11 220 lbs. This may have something to do with it I guess.

March 18, 2014 at 11:32 am
(470) Mia says:

Im reading all these stories and find that I have had many of the same problems. The blackouts is my biggest issue, especially since it can happen after 1 or 2 drinks or 6 drinks without warning. I literally feel perfectly fine then I lose hours during which I am combative rude and irrational. Completely the opposite of me. My question if anyone can answer is that this is all happening AFTER Ive been taken off the medication!! Thats whats driving me crazy. Did this medication permanently alter my brain chemistry so that I can no longer tolerate alcohol?? Anyone having these problems POST medication??

March 23, 2014 at 6:14 am
(471) Suzanne says:

I too have just realised that my alcohol problems only started shortly after I started this medication.
I previously had a huge tolerance to alcohol (not something to be proud of I know). After taking this drug for 4 1/2 years I have developed a craving for alcohol, I don’t have to drink every day, but when I do I can’t stop. I feel absolutely fine then without warning the next thing I remember is waking up with that familiar ‘oh no what have I done?’ feeling. There is no ‘oh I’d better have a glass of water I feel a bit tipsy’ – it’s straight to blackout stage, but I can still function (so people tell me) for hours on end.
I have been off the medication now for 4 days (been tapering it and finally have stopped). What I want to know is, will I ever be able to drink again in an acceptable way? Will I go back to normal? If it does how long does it take? Does anyone have any information? I can find lots of info about how anti depressant drugs interact badly with alcohol, but nothing on whether it is now something I have altered forever in my brain??!!

May 14, 2014 at 10:31 pm
(472) Jess says:

So I have been taking the generic brand of this, bupropion 300 mg XL to be exact. I started off with the 150 mg for awhile when I first started. I had also just recently turned 21 last year in October, I started the meds late January. Honestly, every where I turn, people always say to never drink alcohol on anti-depressants. I truly haven’t had a lot of problems with it. I’m just more paranoid about the seizures really but I don’t do or say anothing out of the ordinary when I drink. I really wish I could stop taking these anti-depressants because I feel fine now and I’m basically sick if taking meds.
Since changing to the 300 mg, because my college pharmacy was out of the 150 mg, I have been feeling more lethargic than before I took the meds and being a night owl, I have to force myself just to stay awake to talk to my boyfriend when we both finally have a moment from our college and work schedules. I’ve also been having really annoying mood swings and arguing with said boyfriend more often than when I didn’t take the meds. I’m becoming to realize that I don’t want to take nor should I be taking anti-depressants. My mom gets after me that I need to give it more time to work or I’m going to go back feeling like crap. Well, I gave it enough time and I’m ready to stop. It’s almost been 5 months, I’m feeling great but I’m tired of feeling tired all the time and picking battles with people that I otherwise wouldn’t fight with.
It’s either I stop or drop back down to 150 mg. I’d rather just stop. :/

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