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Read about what side-effects other members have experienced with Zoloft or share your own experiences on our forum.

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May 10, 2006 at 12:15 am
(1) Pat says:

I have gained 30 lbs in 6 months and have problems ejaculating.

May 23, 2006 at 11:02 am
(2) Natalie says:

I tried Zoloft when I reported panic attacks to my doctor… I suspect that this new “wonder drug” is intensifying them. I am plagued with nausea, palpitations, restlessness, trouble breathing and chest discomfort. One of the websites states, “if you experience any side effects, do not stop taking Zoloft”! You are supposed to “wait it out” and feel sick and anxious every day until it kicks in?

Is it me, or is there something the pharamaceutical reps aren’t telling us…?

June 10, 2011 at 5:30 pm
(3) Amy says:

I just started taking this same medication 3 weeks for the same reasons as you; panic attacks. I was shocked to read you had the same reactions that I did; nausea, palpitations, restlessness, trouble breathing and chest discomfort. After calling my doctor several times they have feeling advised me to quit taking it. I wondered if they were just waiting for me to kill over to make this judgement call!!!!

June 18, 2011 at 3:50 pm
(4) Anna says:

I had the same symtoms; however, only for the 1st few weeks. I started @ 1/2 of a 50 mg tablet once per day for 14 days. Then I moved up to the whole tablet @ 50 mg once a day thereafter. I was really afraid as the palpitations and panic seemed to have increased that 1st 2 weeks.

I am happy to report that for me the heart palpitations, the restlessness, the panic all went away. I am able to leave the house now without panic; I am able to drive now without panic and the fear is gone.

However, I have the weirdest vivid dreams. That is the only thing troubling me @ this juncture.
be well

July 8, 2011 at 2:18 pm
(5) Kelly says:

I began taking Zoloft about 3 months ago to help with both my anxiety and PMDD symptons. When my doctor first told me about this treatment, I was very concerned about the side effects. In the first two to three weeks of taking it, I experienced both nausea and headaches. To my relief all the side effects went away and I feel great! I am so thrilled that I stuck it out! Your body needs time to adjust to the medication and once it does, if it works for you, it is worth it. However, if the symptons do not go away please don’t give up. As my doctor explained to me, not everyone can take every SSRI’s, so if Zoloft didn’t work for me, we could try another.

Hang in there and God Bless!

October 11, 2011 at 11:56 pm
(6) Gabriella says:

thank you so much for posting this, it helped me out alot!!!

June 9, 2006 at 2:52 pm
(7) Esther says:

Hi Natalie,

Kind of ironic, right before I read your post, I was just looking up side effects so I’m copying and psting this for you. May be too late, not sure, you may have already changed medications. Anyway, this is what I found:

What are the possible side effects of sertraline?
• If you experience any of the following serious side effects, stop taking sertraline and contact your doctor immediately or seek emergency medical treatment:
· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
· an irregular heartbeat or pulse;
· low blood pressure (dizziness, weakness);
· high blood pressure (severe headache, blurred vision); or
· chills or fever.
• If you experience any of the following less serious side effects, continue taking sertraline and talk to your doctor:
· headache;
· tremor, nervousness, or anxiety;
· nausea, diarrhea, dry mouth, or changes in appetite or weight;
· sleepiness or insomnia; or
· decreased sex drive, impotence, or difficulty having an orgasm.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

I got it from this site:

Good luck! :)

November 29, 2006 at 1:14 pm
(8) April Mureen says:

Zoloft made my sister more suicidal until the psychiatrist got her dosage up to 200 mg, then she was a zombie, then it gave my sister hypomania when she decreased her dosage…she went scary-crazy for weeks with the hypomania and now she’s in a drug treatment center…you couldn’t pay me a million bucks to take this drug. It has a dark side I’ve seen first-hand in my sister…it was not her…this drug took over her brain like a driver controls a car.

December 12, 2006 at 5:28 pm
(9) Michael says:

I’ve also gained about 30 lbs in the 14 months that I’ve been taking zoloft. At first it helped my anxiety attacks, but now I’m getting them again and my Doctor suggested increasing my dosage. I would just as soon just get off of the stuff and learn to live with the anxiety. No good being a fat & anxious, I might as well be fit and anxious.
My son on the other hand is doing great with it. Go figure!

April 1, 2011 at 11:45 am
(10) deborah says:

i also have anxiety attacks there is help contact me for more information

September 30, 2011 at 10:47 pm
(11) anna canova says:

Hi Deborah, just needed someone to talk to and figured maybe being a woman you would understand, on and off for about a year I have been experiencing panic attacks palpitations while trying to go to sleep. I am awakened and it knocks the crap out of me. Drs are always quick to put you on meds, first I was taking xanax at night low dose 0.25 knocks me out I hate taking meds and everything seems to bother me, after my recent attacks which have become frequent and I think I am enterin menopause, dr prescribed zoloft, I am only taking 25 mg, still need the xanax dont want to become a drug addict and you wonder why people get addicted wonder if you have any suggestions. Thanks

December 13, 2006 at 9:10 pm
(12) suzanne Mauro says:

I am taking zoloft for depression and so far ive experienced; weight gain, anxiety, acne, nervousness. The good side of it is that I feel a bit less depressed! Im not as negative, but the side effects stink!

December 14, 2006 at 11:38 am
(13) Roger says:

I’ve been taking a small dose (50mg) of Zoloft since September of 2006, and although it got me through a rather trying time in my life, it also seemed to present some rather unpleasant side-effects:
a)I had a twitching in my facial muscles that became increasingly-intolerable as the months progressed.
b)I seemed to have a mild burning feeling in my lower abdomen that I first thought was a side-effect that would lessen . . only it didn’t.
c)I seemed to become a little manic, and although I initially enjoyed the experience and felt that it gave me a creative and “cutting edge” to get things done, after awhile it became rather unpleasant; seems that I was always “on edge”.
d)What Zoloft “gave” me during the day in terms of reducing my depression, it seemed to take back at night: my dreams were almost without exception fraught with anger and sadness.

I finally touched base with my doctor, am tapering off the medication, and come New Years Day 2007 I’ll be off it.
More will be revealed, and if I start to run into any emotional trouble my doctor will be the first to know. Until then, I’m going to try the “no med” plan.

December 14, 2006 at 11:15 pm
(14) Sandra says:

Boy am I glad I found others having the same problems I am having. I have gained 30 lbs. since June. I quit smoking which made my anxiety worse so the Dr. put me on 50 mgs. I know part of my problem is the quitting smoking, but nothing seems to help lose the weight. Not even one pound!!! I think the added weight is worse than the anxiety.

January 2, 2007 at 12:09 pm
(15) bob says:

recently learned my wife has been taking Zoloft with a noticeable change in personality; arguementative, agressiveness, lack of consideration, and withdrawal. Anyone have similiar observation(s) ?

March 20, 2011 at 11:26 pm
(16) Barbara says:

Yes, my husband has been taking a generic brand of zoloft called citalopram, he still has anxiety fits, sleeplessness, hurts all the time and gains weight. I hate this drug.

August 16, 2011 at 7:28 pm
(17) Robert says:

Yes, I have a very close friend that takes this medication, and she has become very aggressive. The problem is, she doesn’t realize anything is wrong.

January 6, 2007 at 4:29 pm
(18) donna says:

i actually feel that im more aggressive and arguementitive as well. I have also been completely uninterested in sex with my husband. im not sure if this is due to the zoloft or something else.

January 7, 2007 at 9:59 am
(19) kevin says:

My ten year old son is on 100mg of zoloft. He weighs 81lbs. He is very argumentitive and aggressive and when I punish him he refuses to accept the punishment. I have to physically grab him to stop his behavior. When he misses a dose the symptoms are worse. He looks a little bloated to me in the last six months(very lean kid)this coincides with an increase in dosage. I am losing faith in doctors and have none in drug companies. His mother diagnosed him with anxiety(and the doctors went along)as she suffers from depression and is on prozac. They seemed to rush him into drugs without getting to know him. Any comments?

January 8, 2007 at 12:47 pm
(20) Marnie says:

I have been taking Zoloft for almost two months and am already DONE and ready to stop. I have gained 12 lbs. just so far and am easily angered and much more aggressive than I’ve ever been. I’ve been lucky enough to have someone close to me be willing to tell me that lately I’m just mean. I’ve been incredibly short w/ my 5 year-old an have actually SCREAMED at him and spanked him at times when I wouldn’t have before. I’ve never been this way before.
I’ve also had pretty severe “burning” in my lower abdomen and it started as soon as I started taking the Zoloft.
I took Depacote prior to Zoloft for mild bipolar disorder and wanted to try something else because I was feeling so lathargic on that.
I’m now realizing that it was MUCH better than this.
I’m now going to gradually taper off of the Zoloft and going to TRY to stop all drugs and see if I can do it with just therapy from now on..

January 17, 2007 at 7:26 pm
(21) mconover says:

Anyone experiences feelings of over sensitivity? My husband is taking it and is overly sensitive. Maybe a little paranoid.

January 29, 2007 at 4:12 pm
(22) Tanya says:

Wow. This explains alot. I’ve been taking 50 mg for postpartum depression, and was looking forward to getting off of it soon. I’d been doing great for about 5 months, then suddenly, the aggression, sensitivity, and anger thing kicked in. Also, a pretty constant headache over my right eye, sensitivity to light, and a weird, disoriented feeling, like my brain is slow in catching up with my actions. I don’t quite know how to describe it, except that it’s kinda like I have a slight dizzy feling most of the time.

February 4, 2007 at 9:27 pm
(23) Lori says:

I have been taking Zoloft for almost a month now. One of the side effects I have had was VERY vivid dreams. Does anyone know if that is one of the side effects? I checked on another website and it didn’t say anything about it. Has anyone experienced this? Thanx

June 18, 2011 at 3:56 pm
(24) Anna says:

Hi Lori:

Yes! I cannot find “vivid dreams” listed as a side affect but I have the wildest, craziest; makes no sense; wierdest dreams ever.

I hate it. the 50 mg have helped immesnely but I may get myself off this med due to the dreams. They leave me feeling drained and weirded out as soon as I wake up.

February 6, 2007 at 11:31 am
(25) Judy says:

I have been taking Zoloft for about oneweek and already hate the side effects. I feel like i’m full in my chest,no appetite and out of breath sometimes.Should I stop taking this product?

February 6, 2007 at 9:20 pm
(26) Sue says:

After losing another job due to people saying I was short with people I thought I better check out the side effects of zoloft. You guys are great. I had no idea that the argumentativeness was a side effect. I have all of the side effects you guys have shared and Thank God I am weaning off of this drug. I am a nurse and I thought I was losing my mind. I would forget things and other people were really mad at me. I wondered what was wrong with them. After being off for another job loss, I thought I have been on this med for over 4 years and the effects were getting so bad. I am having headaches though as I wean off and more anxiety. Do you guys have any words of wisdom to assist with this. I have to get off of Zoloft asap. thanks for listening. Sue

February 14, 2007 at 12:56 pm
(27) Joy says:

I have been on Zoloft for about 3 yrs for depression and OCD. It really helped. Just recently I had been experiencing agitation and numerous outbursts of anger and rage at my husband. The doctor increased my dosage to 150 mil. and I am feeling calmer but I feel that I could sleep all day and have experienced a slight tremor in my hands at times. I too am having a hard time controlling my weight and have thought of going off of the meds…but everyone close to me seems to think I am a much nicer and more relaxed person on Zoloft. I must say that I do feel better but I am leary of being on this medication for the rest of my life. Any comments.

February 19, 2007 at 10:55 pm
(28) sara says:

When I was taking Zoloft (about 10 years ago?) I experienced really vivid and odd dreams as well. My doctor told me that was a normal side effect.

February 19, 2007 at 10:58 pm
(29) sara says:

My husband feels sleepy after he takes Zoloft at night. This is the second time he has been prescribed Zoloft, but he does not remember experiencing this side effect. Any one else?

February 20, 2007 at 10:35 am
(30) mindy says:

i have only been on the drug for a week but where i had been very motivated a week before i am now uninterested and havent done anything productive. i lost my wallet today and instead of being very concerned i am completly passive. i was off better before

February 26, 2007 at 2:09 pm
(31) Kristi says:

I started on Zoloft Friday Feb 23. Took it all weekend and I already don’t like it. I had a racing heart what felt like a total body shot of Novacain, hottness, panic, extremely vivid dreams. I discontinued taking it immediately and called my doctor. I don’t want to take any thing that makes me feel like I’m having a heart attack or wakes me up in a panic in the middle of the night. Drug companies what a scam.

February 26, 2007 at 9:57 pm
(32) Michelle says:

I have been on Zoloft for about 7 years and want to get off of zoloft because of the many side effects: Loss of memory recall, low libido, agitation, & weight gain(20 lbs.). Is it better to wean off or go cold-turkey? Won’t I still have withdrawal with weaning down?

March 1, 2007 at 8:51 pm
(33) Kevin says:

I am experiencing some of the same side effects that others have posted here. I’ve been on it for over a year and am noticing aggitation, quick tempered, ejaculation (blush) problems, extreme highs and lows (like manic-depressive), and some short-term memory problems. Not exactly sure that it’s the Zoloft as I have MS also. I started on Zoloft after being on Prozac and then Paxil. They weren’t doing the trick. The MS was part of the problem for the beginning of depression to begin with and it doesn’t go away except for help from Zoloft. But not sure how much longer I can stay on the Zoloft. My aggression and short-tempered behavior is getting worse. Hope everyone else that has posted has found some new answers!

March 5, 2007 at 9:27 am
(34) christa says:

My dreams are crazy… I’ve been on-off zoloft for a month and a little more now. I have dreams that are so bad they make me wake up sobbing or shouting. My teeth hurt a little more, dunno if that’s from my teeth moving with the braces or teeth-grinding at night due to zoloft. Zoloft at first was a great thing for me and immediately calmed me down. I am taking it for General Anxiety Disorder and very mild situational depression. I like the euphoric feeling it gives me, but the dreams are killing me. I am overall a happier person, more motivated, and clearer thinker. I haven’t experienced the weight gain yet, and I just started with a physical trainer. I’m not sure how I feel with being diagonsed with depression. I don’t really agree with it. But I do agree that I do not have coping skills and my childhood was extremely depressing(which I feel like I’m over now). I don’t feel suicidal with zoloft, but I’m worried about how many people are having long term effects from it. The dreams are too much for me and I’m thinking about either getting off meds completely or changing to something not so strong. Anyone have the troublesome nightmares? I’d like to share experiences, because I don’t understand where they are coming from. Also I don’t have an addictive personality at all, but I do feel some sort of co-dependence on zoloft. I feel like whenever I have a problem it solves it, and I don’t like relying on a drug like this.

June 18, 2011 at 4:00 pm
(35) Anna says:

My teeth grind @ night too. I wake up[ with my jaws aching eery morning. I thought I must have been clenching my teeth due to the mask I wear with my cpap machine as I was diagnosed with sleep apnea right before the panic attacks.

March 7, 2007 at 12:20 pm
(36) Amy says:



March 8, 2007 at 4:45 pm
(37) candace says:

I have no sex drive and have gained 25 pounds. Is it normal to lose your sex drive from this med?

March 9, 2007 at 12:17 am
(38) James says:

Wow..My doctor is wanting me to get on zoloft for anxiety. But after reading all of this F**k that. I’ll stick taking Buspirone and deal with the palpitations. Thanks for the info and good luck people..

March 13, 2007 at 4:48 pm
(39) Rosie says:

I am supposed to start Zoloft tomorrow and after reading this I am really freaking out. I JUST lost 12 lbs and it was hard enough and to think weight gain is a side effect scares me …these kinds of drugs alone scare me so I just dont even know what to do I am suffering PTSD from an assault 4 years ago this summer…so wow i dont know think i would rather be paranoid then deal with all these nasty side effects.

March 15, 2007 at 7:59 am
(40) BITTER says:

I’ve been taking it since last summer and I experience dizziness, sweating (even in cold weather) and tremors – sometimes it’s impossible for me to hold a pen.

March 18, 2007 at 9:39 pm
(41) jessie says:

I’ve been taking Zoloft for 1 year now for panic attacts. I had been taking Paxil and before that tried Klonopin. Zoloft worked the best for my panic disorder, however I have also gained about 30 lbs and seem to procrastinate about everything. Side effects include dry mouth, vision loss,ED, teeth grinding, muscle twitching in face and hands, and lack of intrest. Other than that, I feel fine!

March 21, 2007 at 9:26 pm
(42) Joey says:

I thought i was going nuts or something
but then I found this site here and sure am glad I did I have been on a 150mg of zoloft for about a year and a half. and another user explained how i started feeling out of no where and here is what she wrote

suddenly, the aggression, sensitivity, and anger thing kicked in. Also, a pretty constant headache over my right eye, sensitivity to light, and a weird, disoriented feeling, like my brain is slow in catching up with my actions. I don’t quite know how to describe it, except that it’s kinda like I have a slight dizzy feling most of the time.

Comment by Tanya — January 29, 2007 @

March 25, 2007 at 5:12 am
(43) Kate says:

I just started taking Zoloft and I feel nauseated and dizzy. I don’t know that I feel less anxious, but we’ll see. I’m going to talk to a doctor about the side effects and other things, will let you know.

March 27, 2007 at 4:15 pm
(44) Christina says:

I was taking effexor about a year ago and because of a severe allergic reaction i was put on zoloft. i am currently taking 150mg and my depression is good…my doctor will not take me off of this drug even though i have a lot of side effects; weight gain(20lbs), vivid dreams, panic attacks, no sex drive…i could keep going…so i have decided to stop the meds myself. i just hope my depression and sucidial thoughts don’t return but i can’t keep taking these drugs. they have made me not care about anything…so i am doing this for my children’s sake.

April 4, 2007 at 8:34 pm
(45) Kate says:

I’ve been on Zoloft for panic attacks for about 7 yrs. Started with 25mg then had to increase to 50 in the last year due to break through PAs. Gradually having increased symptoms of lethargy, decreased concentration, brain fog, decreased motivation, & not caring about things. I used to have energy, want to do things, be able to concentrate and focus. This is gone and I’ve had enough. I’m going to wean off and look into other ways of dealing – if the panic attacks start up again.

April 9, 2007 at 12:46 am
(46) Laura says:

Zoloft immediately gave me disturbing, vivid dreams, that left me feeling tired all day. In a month, I lost all motivation, and was practically just staring at the walls, not going to work, cleaning the house, or even showering. I am weaning myself off of this horrid drug!

April 9, 2007 at 6:18 pm
(47) ang says:

I’ve been taking zoloft for about 3 weeks now and am starting to get weird side effects. My brain feels foggy and I can’t seem to concentrate. I’m always tired, even after sleeping 10 hours. I’m taking it due to post-partum depression but I hate the way it makes me feel. It almost makes me feel like I’m manic-depressive. Does anyone have similar experiences?

April 11, 2007 at 7:25 pm
(48) M J says:

I have been zoloft for 6 months. I had been taking well butrin for years, but I just couldn’t shake a bad episode of depression. I am bi-polar. I am now requesting to go back to wellbutrin. I hate the weight gain, the night sweats,
the bad feeling when waking up from disturbing dreams and the anger inside.

April 16, 2007 at 6:36 pm
(49) Patty says:

I am new to Zoloft and am sleeping all the time and feel like a zombie. I had one panic attack and this feels like overkill to me. Also, my heart hurts. ?

April 17, 2007 at 8:00 pm
(50) Crystal says:

Thank you all so very much! I have a stepson who was just put on Zoloft and I’m now thnking it wasn’t such a good idea. How can any doctor with half a brain prescribe a drug that make aggressive teens more aggressive. This is nuts! Again, thank you!

April 18, 2007 at 6:16 pm
(51) Sarah says:

Ive been on it for two days. first night i didnt sleep and spent most of the night in the bathroom. This is the second time ive been on it. First time they took me up to 250 a few years ago. I took myself off it and am now back on it after been off it for 2 years. I’m hating it! I have this constant off my face feeling

April 23, 2007 at 9:18 pm
(52) Natalie says:

I have been on zoloft for two months. Everyoe is different. It has helped me so much. I felt out of it at first, but now I’m just overall calm. No more screaming at my kids! I don’t think about suicide the way I used to. Everything is not for everybody. If it’s not for you try something else.

April 26, 2007 at 1:44 pm
(53) melanie says:

I have been on Zoloft since december and it has worked great for me I am calm but the last few weeks its like I cant get enough sleep I feel like my memory is going due to feeling tired. I wake up and I feel like I havent slept and my husband has been complaining about me snoring and I am not a snorer. I am only on 50mg I was wondering if I should try taking it every other day?

April 28, 2007 at 9:38 pm
(54) Jan says:

Has anyone experienced pain in the leg’s calf (not DVT) and/or involuntary leg twitching/spasims please?
Thanks Jan

May 11, 2007 at 4:36 am
(55) Sue says:

Like Melanie I am always tired and lethargic and my husband is complaining of me snoring but I put the snoring down to the weight gain. When people say they have gained weight, I wonder is this an increase in appetite and overeating or simply weight gain. I’ve found I just can’t stop eating, I have short term memory loss, tiredness and lack of libedo. I’ve been on Zoloft 6 months, 50mg, and am ready to come off it. Despite all the side effects, it got me through a very rough time but now the side effects are outweighing the good.

May 11, 2007 at 9:34 pm
(56) Kimberly says:

I was Zolofot when I had a baby at 26 weeks for postpartum. It was great. O Now, I am on it after 7 years. My jaw hurts from the tightness in it and I have an upset stomach all day. I do not want to gain weight but I am hungry. Surely there has to be something that you can take to just help. Any suggestions?

May 21, 2007 at 5:34 pm
(57) amanda says:

I just saw the message about jaw tightness. I have always suffered from TMJ but since I have been taking zoloft (100mg) it is like I can’t relax my jaw and thus keeps me in a chronic tense state. I also feel no compulsion to do anything and have to make myself accomplish anything. I am currently detoxing from the zoloft and it is not going well but this to shall pass.

May 21, 2007 at 11:07 pm
(58) Teresa says:

Wow I was just prescribed Zoloft for my PMS or whatever they are calling it now? From some of the side effects people have experienced with anger and aggressiveness etc… this is what this drug is being prescribed to help me with. After reading all these personal accounts with Zoloft think I will pass on it.

All these replies and not one good experience with it? Kinda tells you something. Gaining weight is something I refuse to do. I will just deal with my PMS and so will everyone else. LOL

May 21, 2007 at 11:07 pm
(59) Teresa says:

Wow I was just prescribed Zoloft for my PMS or whatever they are calling it now? From some of the side effects people have experienced with anger and aggressiveness etc… this is what this drug is being prescribed to help me with. After reading all these personal accounts with Zoloft think I will pass on it.

All these replies and not one good experience with it? Kinda tells you something. Gaining weight is something I refuse to do. I will just deal with my PMS and so will everyone else. LOL

May 21, 2007 at 11:07 pm
(60) Teresa says:

Wow I was just prescribed Zoloft for my PMS or whatever they are calling it now? From some of the side effects people have experienced with anger and aggressiveness etc… this is what this drug is being prescribed to help me with. After reading all these personal accounts with Zoloft think I will pass on it.

All these replies and not one good experience with it? Kinda tells you something. Gaining weight is something I refuse to do. I will just deal with my PMS and so will everyone else. LOL

May 21, 2007 at 11:07 pm
(61) Teresa says:

Wow I was just prescribed Zoloft for my PMS or whatever they are calling it now? From some of the side effects people have experienced with anger and aggressiveness etc… this is what this drug is being prescribed to help me with. After reading all these personal accounts with Zoloft think I will pass on it.

All these replies and not one good experience with it? Kinda tells you something. Gaining weight is something I refuse to do. I will just deal with my PMS and so will everyone else. LOL

May 21, 2007 at 11:07 pm
(62) Teresa says:

Wow I was just prescribed Zoloft for my PMS or whatever they are calling it now? From some of the side effects people have experienced with anger and aggressiveness etc… this is what this drug is being prescribed to help me with. After reading all these personal accounts with Zoloft think I will pass on it.

All these replies and not one good experience with it? Kinda tells you something. Gaining weight is something I refuse to do. I will just deal with my PMS and so will everyone else. LOL

May 21, 2007 at 11:07 pm
(63) Teresa says:

Wow I was just prescribed Zoloft for my PMS or whatever they are calling it now? From some of the side effects people have experienced with anger and aggressiveness etc… this is what this drug is being prescribed to help me with. After reading all these personal accounts with Zoloft think I will pass on it.

All these replies and not one good experience with it? Kinda tells you something. Gaining weight is something I refuse to do. I will just deal with my PMS and so will everyone else. LOL

May 27, 2007 at 11:40 pm
(64) Karen says:

I have been taking 50mg of Zoloft for over 10 years. It has been the only med. to stop my panic attacks. I have gained about 90 lbs, live in a constant brain fog, don’t feel like me, don’t have the motivation to care about much of anything, never care about sex, and have tried many times to get off this drug. I would always have the brain zaps so bad that they would nearly drive me crazy. Then the panic attacks would come back with a vengence. I could not get back on the med. fast enough to ease the pain and misery of withdrawal. This time I have been decreasing very very slowly, down from 50mg. to 25mg in about three months. I am taking Clonazepam 1mg. at bedtime and it is helping with the panic attacks,and I have had no brain zaps yet. I plan to keep decreasing this drug over the next few months and get completely off of it. I will celebrate that day. I am already feeling better and the brain fog is lifting. I just hope I can get the weight off! I hope my information helps someone out there!

June 6, 2007 at 2:23 pm
(65) s russell says:

My 6 year old son has been taking Zoloft for a few weeks now. His doctor just increased his dose two weeks ago to 1ml. He has always been a quiet passive child but in the past two weeks has been in trouble at school almost every day for bullying. Pushing, pinching, and just being aggressive with the other kids. I was curious if anyone had any of the same experiences with their children.

June 22, 2007 at 10:21 pm
(66) mohammed says:

Iam taking zoloft for 6months ,it help me alot,I tried to get of it butmy problems seemss to come back,my mind going blank and canot concentrate onany thing.because of depression I lost 18 lb
.side effect i have some rash on hands and pain in my leg calves at night shortly after going to bed.I plant to get ofit gradually i am on 150 mg
in my case so for i have positive than negitive effects.


July 11, 2007 at 12:14 pm
(67) Pam Resetar says:

I have been on Zoloft – 50 mg – for 7 months. I originally went on it when my father died. My husband thinks I am much easier to get along with, calmer and slower to anger. However, I have gained weight even though I am not eating more. My clothes are no longer fitting and this sucks! I’m stopping!

July 20, 2007 at 1:10 pm
(68) Doug says:

I have been on Zoloft for only three days. I am already feeling much more agitated, have trouble ejaculating, have a dry mouth, diariah, loss of energy and focus. I am thinking of stopping. I take a mood stabilizer for bipolar, as well as Wellbutrin as an anti depressent. I was feeling pretty good with those two, with virtually no side effects. I was still dealing with social anxiety so my Dr. suggested zoloft. The plan was to stay on Wellbutrin while the Zoloft kicked in. Once before I had tried another SSRI–lexapro, with the same side effects. Especially the ejac problem. No problem getting **sorry for the graphic talk** hard, but couldn’t bring the show to a close. NO Thanks!! All of this just after three days. No four weeks for me. Don’t know what I am going to do, I suspect maybe the side effects might taper off, but after hearing the other comments it doesn’t seem so. Good Luck everyone.

July 23, 2007 at 4:21 pm
(69) Heather says:

I have been on Zoloft for about 2 1/2 years for panic disorder and my dosage has ranged from 50 mg to 100 mg. I have really not had any negative side effects except for some intermittent insomnia which I take Ambien for. I was on Zoloft once before and weaned myself off of it because I thought I could just deal with the panic attacks myself. That was a very bad idea because the panic attacks came back, I could not deal with them myself, and I was 3 months pregnant! Under my psychiatrist’s guidance, I went back on Zoloft anad have been on ever since. I suppose if I had the side effects that some of the other posters have had, I would have different feelings toward the drug, but to me it is something I will probably continue to take for a very long time.

July 23, 2007 at 7:48 pm
(70) Marcella says:

I have been on zoloft for approximately 2 months for PPD. Initially I was on 50 mg but it was making me WAY too groggy during the day and insomniac at night. I went down to 25 mg and the sleep issue was resolved. I have had dry mouth so severe that my lips feel chapped and swollen as well as my tongue. This did not occur until after I dropped the mgs. Other than that (which is pretty unbearable)I have noticed a MARKED difference in my attitude and moods. I lost 15 pounds but that may be due to no booze!

August 15, 2007 at 11:25 pm
(71) Sadi says:

I was just prescribed Zoloft for post partum depression, but after reading your comments I think I will pass. I will just have to cry it out on my own.

October 9, 2011 at 2:54 am
(72) Cpop says:

I was sooooooooo anti anti-depressants for so long, ive been on 50mg of zoloft for 2.5 weeks and WOW i wish i had have taken in 2 years ago after i had my daughter,……. all i can say is, they are working wonderfully for me, try them, they might work, they might not. at least if you have bad side effects you can go off them and you will have a legit reason for feeling like crap. If they work for you, then YAY, just get friends and family to monitor your behavious and mood so u get an outside perspective on how they affect you. I wish i wasnt so in denial about my post natal depression and took them sooner.

August 23, 2007 at 1:36 am
(73) Mom says:

I just wanted to offer some encouragement, since there are a lot more bad experiences posted here than good ones… My oldest son took zoloft for about 9 months at age 14-15 and while he had some side effects (weight gain, felt a bit foggy) it helped a lot for his anxiety and emotional extremes. If someone is taking zoloft and hasn’t had side effects, they might not find this site. Take care, everybody!

August 23, 2007 at 5:41 pm
(74) 2nd time around says:

I actually took Zoloft for a few years to battle my OCD and had very good results. Unfortunately, I had to switch to Prozac a year ago, as Zoloft was not covered when I changed insurance carriers. Before taking Zoloft, I took Paxil and gained about 25 pounds. This in itself can make any person depressed; so I told my doctor to switch me to another prescription that wouldn’t cause weight gain, thus introducing me to Zoloft. In 1 month I dropped all of the weight I had gained with the Paxil. My insurance now covers the generic brand of Zoloft and I have just started it 3 days ago. I am feeling very tired, but am hoping that this shall pass once my body becomes acclimated. I really hope I don’t gain weight this time around.

September 10, 2007 at 9:00 pm
(75) Court says:

Is it normal to get rashes all over you body while taking this crap

October 3, 2007 at 5:08 pm
(76) Lisa says:

I was recently perscirbed zoloft for postpardom depression after having my baby girl. After taking this medicine for 3 days I couldn’t stop moving, had dilated pupils, swelling around my eyes, insomnia, and crying outburst. On the other hand I have lost weight on the zoloft. And I am wondering if I should keep taking it for the weight lost. But I HATE the side effects!!!!

October 4, 2007 at 12:43 pm
(77) Tai says:

This is my 2nd time on Zoloft and I have only been on it for about 3 weeks but this is miserable! I can’t stop moving my arms, legs, hands and feet (especially when I am laying in bed trying to fall asleep), my mouth is dry, my nose is stuffy, I have chest pains, my hands and body sweat a lot, I twitch, I have weird pains in my tummy and legs, I am sooo tired, lethargic, and unmotivated, I lost my desire to have sex, and I forget a lot. The first week was bad with headaches, insomnia, dilated pupils, and upset tummy. I need this for my anxiety but if these side effects dont go away after another month I QUIT!!!!

October 5, 2007 at 10:02 pm
(78) gina says:

hi everyone! i just started taking zoloft 3 days ago because i have been suffering with panic attacks and social phobia for about 6 mos. now. i am reading all the posts, and am having a hard time being positive about the outcome of the meds. people keep telling me to hang in there and wait till my body adjusts. i have been VERY sleepy all the time, and feel like im zoned out constantly. will this stop soon? i have been much calmer though, and i feel more in control of myself. i did have a panic attack at work this morning though, and it was a pretty rugged one. is that normal?

November 12, 2007 at 11:12 pm
(79) Anne says:

Hi nice to find company on a horrible journey. Been on zoloft 2 motnhs and increased slowly to 100mg…every time I increase dose, I get a bottomed out leaking soul feeling……I was depressed..now I am sooooooooooo depressed and anxious. Weight loss not gain…I think I will lower dose..these feelings shouldn’t get worse while on medication.

November 25, 2007 at 9:33 pm
(80) DJ says:

Hey everyone. I have been dealing with depression for many years now, and have always been against the idea of taking a drug for it. Just recently, I had almost convinced myself that I NEED to take something. I used to have suicidal thoughts, but (miraculously)after becoming a father it no longer crosses my mind. My daughter is almost 2, and literally that idea has been wiped from my thoughts. However, I often have feelings as though I can’t deal with myself, Like I want to snap and go crazy……..Usually these issues come out of no where. I can be happy one minute, and then get the worst depression and worthless feeling the next. (which generally lasts at least a few days) My wife was on Zoloft for awhile and it really helped her, which is why I’ve kicked around the idea of taking it. If anyone has any suggestions for me, I could really use the help.

January 24, 2008 at 3:09 pm
(81) tonya says:

I have been on Zoloft for 12years. And i think its time to get off of it. However I am very scared because I dont ever want to go threw what I did in the past. What is the best way to wein off it? I have gained weight and I have had head tremours lately. I am starting to worry.

February 7, 2008 at 3:24 am
(82) sam says:

I have been on Zoloft for more than a year. All I have to show is 9kgs of weight and anxiousness. I enquired about the weightgain in the beginning and was told that Zoloft does not have that as a side effect. I could not sleep, therefor I was prescribed Molipaxan as well. I have uncontrollable trembling of the hands daily – where is this leading to

March 2, 2008 at 10:57 pm
(83) alan says:

I’ve been taking 12-25mg of zoloft/sertraline for a few years now, and it has really helped me with my depression. I tend to be hyper-sensitive of meds which is why I cut my pills in half or quarter. I’ve complained about ejaculations problems to my doctor, who thought adding wellbutrin would help cancel out the side-effects. Instead, I ended up feeling totally juttery and like I wanted to scream at the top of my lungs all the time!!! I went off the zoloft for a while – not more ejaculation problems, but my depression symptomology returned. Back on at 25mg, and instant ejaculation problems again. Is there anything I can add to this to help mitigate this problem?

March 5, 2008 at 9:41 pm
(84) Martie says:

I’ve been on Zoloft for 12 years. It is a wonder drug. I don’t know what I’d do without it. Only side effect I’ve ever noticed is a decreased sex drive.

April 4, 2008 at 1:13 am
(85) earthchild says:

I have been depressed most of my life. Years ago I was on Serzone for a year. Since then I have been drug-free. But recently the stress at work has become unbearable so my doctor prescriped Zoloft, 50mg once a day. I just started today. I’m hoping I don’t have the side effects some people have mentioned here. I just didn’t think I could continue without some help.

April 7, 2008 at 4:10 pm
(86) Todd says:

Anyone prescribed Zoloft should just try it. Don’t let the negative feedback here stop you. Most people that have good results probably aren’t searching the net for answers. If you don’t like the sides, just quit taking it.

The first few days I was on it, my stomach was upset and I felt very drowsy. Those feelings were gone in less than a week. It’s now been five months since I started and the sides I’ve experienced throughout are: dry mouth, lower sex drive, and a bit of “brain fog.”

However, the good outweighed the bad because I was so depressed that I couldn’t function. Zoloft helped me get through a tough time in my life. I plan on quiting soon. Hopefully the depression won’t return.

April 9, 2008 at 10:13 am
(87) Chris says:

Thanks everyone for sharing! I have been on Zoloft for about 1 year now, and I am going to gradually tamper off because of the side effects. At first, it was a wonder drug. I was having a lot of problems with depression and anxiety, and it evened out my behavior imeediately.
As time had gone on, the side effects have intensified. I have the WORSE leg cramps at night, insomonia, I sweat all the time – even in the cold (and I live in Minnesota!). I am tired all of the time and have gained 25lbs. I am totally undermotiviated and withdrawn.

It seems like this is a good short term drug for some people.

Thanks again for sharing!


April 22, 2008 at 12:28 am
(88) earthchild says:

Just an update. After 2 weeks on Zoloft I experienced the most intense and frustrating insomnia I have ever felt. Three nights with practically no sleep at all. By the third night I was sure it was the drug. That night I didn’t take it but instead took it first thing the next morning. I actually slept that night, and the next, and it’s been 3 days now and I haven’t taken anymore. I’m almost afraid of what the side-effects will be if I take it again. I’m hoping I can either get my prescription reduced from 50mg to 25 mg or get off it completely. I want my LIFE back!!

April 22, 2008 at 3:56 pm
(89) BeBe says:

I just want everyone on this post to know that I am praying for you. I, too, have suffered long term depression and anxiety. I am now off all meds. I truly believe these medications are very good for some people who are at life’s extreme. However, I think there is more of our population on this than necessary. I encourage to get second opinions from doctors…to do research…to find out what it is that has brought you to this point whether it’s through talking to someone like a pyschiatrist, or confiding in your general practioner or a family member. Medicine is not always the answer. I just went through a series of very serious tests because the doctor’s were concernend I was developing a brain tumor or had first symptoms of MS. Needless to say, I got off of the 50 mg of Zoloft I have been taking for several years now. My poor husband has agreed to help me through the tough withdraw symptoms…but I WILL make it through. I want my own mind back, and do not want to have to depend on a drug to make me happy. I truly belive diet plays a tremendous role in the things that afflict us. Please know you are not alone!

April 23, 2008 at 10:32 pm
(90) earthchild says:

BeBe– my thoughts are with you. I gave in this morning and took another Zoloft. But I also phoned and made an appointment with a counselor. AND I got off my but and got outside and went for a walk. I feel much better tonight and will try not to take Zoloft for another day or two. There are other health problems I am dealing with at the same time which may or may not be caused/linked with my depression. Thanks to this forum though I truly realize that I am not alone in this struggle. Thank-you!

April 27, 2008 at 10:48 pm
(91) Laura says:

i was on zoloft for 6 years..i gained 40 to 50 lbs..i just stopped taking it two weeks ago today..feel sooo much better..has way to many side affects.

May 11, 2008 at 11:59 pm
(92) mellody says:


May 17, 2008 at 6:08 pm
(93) D says:

I was put on Zoloft a while ago for a problem unrelated to depression. I was having chronic headaches, and it had the potential to help. It didn’t, and the main side effect I got were the vivid dreams (which I really kind of enjoyed). But since it wasn’t having the desired effect I stopped taking it. I’m very annoyed that no-one bothered to tell me that you’re not supposed to stop cold turkey, that could have been dangerous, but perhaps I got lucky. I didn’t get any nasty withdrawal effects that I noticed.

For people coming here who have just been prescribed Zoloft, I think you need to take these posts with a grain of salt. This looks kind of like a self selecting collection of only negative stories. There’s no way to tell which reported symptoms are really caused by the Zoloft and which could be the result of some other problem, diagnosed or not.

May 19, 2008 at 7:03 pm
(94) sorry says:

Started Zoloft (200 mg) in September 2007, with klonipin (up to 75 mg) per day. Everything was great, sharper thinking, energy productive then 5 months later i began to crash. Stopped klonipin -extremely addictive- withdrawal was the Worst, I thought. Until the doctor decided to wean me off zoloft to prozac. He prescribed 20 mg prozac and told me to decrease dose of zoloft by 50mg every day. I am sick to my stomach, more anxious and depressed than I ever was and extremely lethargic, can sleep an extra 5 hours per day. I don’t know what to do but I am angry and aggressive.

May 21, 2008 at 1:32 pm
(95) Katrina says:

I’ve been on zoloft for at least 10 years. Recently I had a a mishap and was only taking 25 mgs a night, I usually take 50 mgs a night. And I noticed I had vivid dreams (well more nightmares) were I wake up with my heart racing and feeling sick. And I had more anxiety problems on the lower dose. Last night I took my normal dose 50 mgs again, in hopes of helping the anxiety. I am also on Trazodone 150mgs, and Geodon 40mgs.
I didn’t notice much weight gain but I am a heavier person since being on medication for 12 years, the only thing a noticed is it’s harder to lose weight. I also have jaw problems and have to wear a night appliance to keep me from clenching and grinding my teeth. And increased headaches but that can be from my jaw problems. I occasionally get muscle twitches though they aren’t usually that bad.
Overall zoloft has helped me alot with dealing with everyday stress. The side effects aren’t so bad, the withdrawl is the worst. All ways talk to your doctor before lower or stopping your medication. If they don’t want to suggest another medicine or adjust your dosage, GO TRY ANOTHER DOCTOR! It may help I had to a few years ago and it really helped!

May 23, 2008 at 5:00 pm
(96) Todd says:

I just want to reiterate what BeBe said. Medication will not fix your problems. You have to understand why you’re depressed in the first place and work from there. I always thought anti-depressants were for weak-minded people, until I suffered from it myself.

However, I believe meds can be a “crutch” to help you work through your depression. I would definitely recommend anyone who is depressed to see a counselor. I’m currently seeing a psychiatrist, and I believe it will help.

Also, if Zoloft doesn’t work for you, maybe something else will. Don’t just rely on your doctor. Do your own research and be aware of all of your options. Just remember these medications are not the cure! Good luck to everyone here.

June 10, 2008 at 12:50 pm
(97) S says:

My fiance takes Sertaline (Zoloft) and we haven’t spoken for 2 days now. His doctor decided to change his dose from 150 per day to 200 per day only…before he took 150 in the morning. Now he is supposed to take 100 in the morning and 100 in the evening. Well, he always forgets to take his evening dose and needless to say, he suffers terribly. He has been at the same company for 20 years and has never been in trouble-got into an argument with his supervisor and was sent home on Admin Leave. He stayed home for 3 weeks while they decided what to do-he is on probation for 6 months and has to participate in a “fitness for duty” program. They said he displayed “eberrant behavior” that is totally out of character for this gentle giant of a man. This has all been happening since January of 2008. We have struggled with a gun, I have found him in a drug induces almost coma state from taking klonipin on top of everything…He forgot to take his meds last week several days and sure enough, it has caught up with him. He told me yesterday, “Then why don’t you go home” when I suggested that he talk to his doctor about his roller coaster emotions. He has extreme difficulty with ejaculation, sleep, throws up if he starts coughing, sometimes his hands shake so badly (now I know why)and it just seems like such a terrible way to live life. I just know that this relationship is not working, the way he treats me – so very very cold – is not a healthy, happy relationship. It simply is not working. Now I am at a loss as to what I should do! Give him the silent treatment and not contact him or go to his rescue??? I am not so sure I want to take care of a man-child-although we are not formally engaged, we have the intention of marrying. If he proposed today, I would have to say, “no”. That is so sad…. I am tired…

August 18, 2008 at 7:34 pm
(98) Ashley says:

I noticed that these posts have deterred numerous people from trying Zoloft. I might also mention that most of the people that are posting are the people that are having problems with the drug…because the people that aren’t having problems aren’t looking at side effects and writing about the benefits. So in part, it looks like everyone in the world is having a hard time with zoloft when that really is not the case.

I have been on zoloft for about a year and a half, and while there are definitely things about it I’m not happy about…those things are very much outweighed by the benefits. I suffer from a panic disorder and was living in perpetual fear before zoloft came around and alleviated my symptoms. My last full blown panic attack was over a year ago. I credit it to saving my life because I thought I was going crazy and leaning to the suicidal side prior to taking it.

The only reason I am on this site looking at side effects is that I’m interested in knowing what to look for while I attempt to taper off it. My anxiety is up because I’ve recently gone from 100mg to 50mg.

My side effects while on it have been low libido and a certain numbness to what is going on around me. I’m not a zombie by any means, but it takes quite a bit to upset me or make me laugh out loud. Mostly, I am worried about my low sex drive and that is why I want to get off it. But only if I can get off it without having panic attacks. I also have some weight issues and it’s been difficult to lose due to cravings.

But I can’t emphasize how important it is to understand that these drugs effect everyone differently. Just because one person has a bad experience doesn’t mean it’s not going to help you out. It’s all trial and error. These drugs really haven’t been around all that long.

Also, almost all the drugs I’ve tried have given me increased anxiety at the beginning of starting them. If you can wait a few days, it will subside. And Zoloft works faster than most of them. Cymbalta was my personal nightmare, Paxil didn’t do a thing for me other than take away my sex drive, Lexapro made me sleepy 24/7 so I wasn’t awake to feel anxious…Celexa wasn’t that different from Lexapro. Wellbutrin gave me my sex drive back, but didn’t work on my anxiety. Some of those drugs are other people’s miracle drug…or they cause problems or they are just “so-so”. But don’t take one persons experience and expect to get the same results. They are different for everyone.

October 2, 2008 at 4:26 pm
(99) cher says:

I have been on zoloft 50mg for almost three years now. I started taking it for panic attack, anxiety, and a crappy time in my life. now alomst three years later im trying to come off of them slowly and am in my final stages. My side effects are headaches, dizziness,sometimes I feel like im going to faint,night sweats, very nauesous 20 mins after, when I do take the pill and my dreams are absolutly deathly scary. Ive notice my anxiety is somewhat starting to come back. I rather go through this though and push through until I get through. This drug makes a person feel like a zombie and numbs you at times. Hope thsi helps any… and if you have any comments feel free to post.

October 11, 2008 at 1:41 am
(100) Kim says:

I have been on 50 to 100 mg of Zoloft daily for atleast 8 years now. If I STAY ON IT, and don’t MISS doses, I don’t have anxiety, depression, fatigue, fits of rage or hostility, dizziness or hot flashes. But I can honestly say, I have tried three others, and this one has been a GOD SEND- It really has improved my life. The only side effects are drop in libido, and some short term memory loss, but nothing major, I’m a nurse, so believe me, or I would have my doctor take me off of it (gradually, to avoid withdrawel side effects-which are NOT PLEASANT)and I just want to encourage everyone to weigh the benefits against bad side effects, and know that skipping doses can cause the side effects as well. It takes several weeks or months to get the Seratonin to the level that works best for you. Don’t expect to feel super duper overnight, that’s not realistic. It is NOT addictive-ask any reputeable Psychiatrist- and as far as weight gain, you really just need to stay active and keep your metabolism going-snacking frequently on fruits and vegetables for example. Especially if you’re over 30 as I am. Metabolism slows as you get older. It is so nice to be able to enjoy life.

October 27, 2008 at 12:19 am
(101) kristen says:

ive been taking zoloft for about a month and a half now. i felt awful for the first month, like i was gong to die! i was put on it because of panic attacks and heart palpitations, also lack of sleep, for over 3 months i couldnt sleep, sleeping pills didnt even help! about two weeks ago ive noticed (all my friends and family and coworkers also) my change in personality. i am much more pleasant. i feel great all the time, i dont get frustrated or mad like i used to. unfortunately i still have some side effects. some twitching of the muscles, im dizzy all of the time, its tough to drive sometimes (i take it at night). the worst however, is the tightening in my jaw. i feel tight in there constantly. i clench all the time. this seems to be the only unbearable thing. im weighing the advantages, i love how it makes me feel but my jaw is very sore all the time. i have an appointment in a few days, i may try something different…

November 10, 2008 at 4:19 am
(102) Shane says:

I’ve been taking Zoloft for a number of years, not to long after 911 did I begin to take the pill because i had trouble sleeping I did not rest for about 3 days in a row and it scared me to death, I went to a mental healthcenter and my doctor/psychiatrist gave me Zoloft to take for my and I quote his comment my ‘anxiety disorder’ and then they gave me Vistrl for my sleeping disorder, I used it for a while then i was able to stop using it but i took Zoloft for another several years because i was so scared of not beingh able to sleep, I rested fine but then all the side effects In gained about thirty pounds that i’m still trying to burn off and I have had extreme hair loss, waking up and finding tons of hair on my pillow and extreme heaviness in the eyes and fatigue, to where i could not even do my weightlifting which made me literally cry, I have been off it for about a month now, I was wondering because in august near the months end i had been taking 50 mg the whole tiome i’d been taking Zoloft then I halved it and everyday took about 25 mg and then the next month i started taking the 25 mg one day and no pill the next day, I started at the end of september stopping completly and have felt like hell almost everyday since, I;’ve had a ton of side effects i’ve had extreme drowsiness, I’ve had a swelling in my left leg just beside the kneecap that i got while using the pill and then it is stil there, I wondered if anyone can help me at all, and is there ever gonna come a time when i will fel better ever again, or do i need to see a doctor?

December 16, 2008 at 10:21 am
(103) Sarah Jones says:

I was really hoping I could have found an experience similar to mine on here but I think it must have been fairly unique….as soon as I started taking Zoloft, I had more energy than I had ever had in my life, enough to work out at the gym for HOURS upon HOURS each day, which I can’t do normally….I wasn’t eating hardly anything yet felt I was getting fatter and fatter by the day, I felt soo fat, I went to the doctor and he said I had actually put on kilos…I only stayed on it a few days but I wondered what would have happened if I had stayed on it…I know as well as the extra energy I started to feel very irritable and extra assertive and outgoing, I did not feel myself at all…I started LExapro shortly after, and did not have any real troubling side effects at all, apparently most people find Lexapro easier to take. If anyone has had this same experience I would love to talk to them…good luck ya’ll

December 24, 2008 at 1:50 am
(104) steelmaker says:

I was introduced to this drug through a doctor that my wife uses. I saw the therapist due to some social anxiety problems that I thougt I had but after going through the program and taking Zolaft I have come to the conclusion that the therapist take advantage of alot of people that don’t need medication at all. These guys would put you on medication and bring you back every month for an evaluation that consited of, “how are you feeling”- “ok” “we’ll great I’ll see you again in a month”. If you said that you did not feel ok they would raise your dosage 50mg. I went for years without missing a day of work to missing alot of work because I didn’t know what this stuff could do. My pschiatrist would not even look me in the eye when he talked, (talk about social anxiety). I have been very easy to get along with at work and at home…. to a point. Then I explode. No not violenty but this stuff lets you get walked on to a point that is just rediculous. After that you just let it out in some kind of stupid tantrim. I have been on 25 mg and have done nothing but sweat at night and snore since I have been on it. I think that getting off of it will be better for me and my family. Note to all readers, It’s ok to get mad every now and again, passion is what makes us human, getting offended by what people say when others are mad; its you’re right too, not a sickness. Its called being human. The people that perscribe medication for that are called “con artists” – with a degree. Well I have a degree too but it doesn’t qualify me to call you “crazy” either. If you go to your regular MD they will perscribe you the same medication without the same BS checkups. Try it. You’ll see.

January 18, 2009 at 9:58 pm
(105) Andrea says:

For all of you that are concerned with your weight gain while taking Zoloft or any of these medications, there is hope. While taking these medications I gained 15 pounds in 5 months. I started my research about how to lose this weight gained due to Zoloft and I found the Serotonin Power Diet, which totally worked for me, plus it increased my energy level and my mood. I totally recommend it, plus you can live the rest of your life according to this diet, because it is non restrictive. You start losing weight since the very first week.

February 7, 2009 at 2:45 pm
(106) Sabrina says:

Hey, I started zoloft about 3 weeks ago and am currently on 3/4 of 25mgs for anxiety/minor OCD. My anxiety is almost completely gone :) The first week, I had horrible side effects and really bad anxiety and even a panic attack, but those have now subsided besides the jaw clenching and yesterday’s random crying spell! All in all, in time I think zoloft will pull through and work for me. I am not anxious at all anymore, so I know it’s working.

February 11, 2009 at 10:14 pm
(107) Tracie says:

I’ve been on Zoloft for about 2 years now. It helped tremendously with my depression and anxiety. My main complaint is that without taking Wellbutrin to counteract Zoloft’s sexual side effects, having an orgasm is close to impossible if not so. I feel I’m too young to deal with this for my whole life so I’m trying with fingers crossed that the switch over to Cymbalta will help me. I just read on that forum that some women find it impossible to have an orgasm with that too which is completely depressing to me. In the 2 years I’ve taken Zoloft I gained 35 pounds. I’ve tried to quit taking Zoloft cold turkey in the past but found the withdrawals excruciating. I have no way of explaining it other than an electric pop in my head that leaves me feeling like I’m on drugs. (Which I guess I am lol) Depression isn’t funny at all. It’s like a choice, do I want to be overweight and asexual and sad for those problems, or do I want to be depressed and filled with anxiety but skinny and sexual? And has anyone ever tried explaining this dilemma to a non depressed person? No one gets it!

February 13, 2009 at 3:18 pm
(108) cher says:

I had been on zoloft for two years and am now off for the past year.The unfortunate thing about zoloft and many of these pills is that the after effects are not dicused. There has not been enough tests done out there on these meds to know the long term effects of these while being off. No one wants to be on pills for the rest of their lives but once coming off I have noticed changes this being a year later. I hope it goes away eventually. I guess each person is different. Hopefully everyone can one day get off these and not have long term effects

February 18, 2009 at 11:36 am
(109) Pree says:

IF you come off Zoloft. Do you lose the weight that you gain while being on zolft.


February 28, 2009 at 3:59 am
(110) lola says:

After years of trying various medications (2 pages worth & a few hospital stays later), I finally tried zoloft. it has been almost 10 years
that i’ve been on 100mg. I suffered from free-floating anxiety, extreme panic attacks, agoraphobia and ocd. my experience will differ from others because we are all unique- no two people have the same biological make-up, nor can we compare our brain chemistry with one another. What works for mr.jones will not work for mr.smith, so it is “trial & error” with medications. There will be “good & bad” with all medications, so zoloft is no different. Now, it will be 10 years for me & I no longer SUFFER from debilitating anxiety/panic attacks, nor agoraphobia (thank the lord!), nor dark depression & the ocd (being the most difficult disorder to treat) is 80% managed. I got my so-called “normal” life back & that is worth the odd side-effects I have to live with. Extra sweating occurs; extra weight gain because many anti-depressants/anti-psychotic drugs effect thyroid function & I have hypothyroidism to begin with; horrible vivid dreams; heat-intolerance; tingling sensations in hands, face, chest; electrical fireworks in my head while asleep & I’m aware of them; awake feeling worn; sudden flashes in my eyes; decreased libido; poor memory & I’m sure I’ve forgotten some others…….but, I feel like I’m alive now–before the zoloft, my life was like living a slow death, physically, mentally & emotionally…………….NOW, I have attempted to wean myself off but unfortunately, what I experienced before, returns within many days. It is known that the symptoms may return & can be magnified X 3 but I did not wait to find that out because I immediately went back to my daily dose. I had 2 relapses when I was on micro doses of zoloft, so I know that 100mg is ideal for me. Some need 50mg, some need 200mg & just like my thyroid medication, it needs to be adjusted to suit my needs, not what the general public might need….. There is so much about the human brain that has yet to be learned & it is pointless to “buy into” comments that are made by many, as being “scientific fact”, such as “medication just masks the symptoms”,or “you can stop anxiety or panic attacks by willing them away”, or “only weak-minded people give into these disorders”, or “anxiety/panic attacks won’t kill you”….well, one won’t but the ongoing chronic stress that these disorders place on the heart, the mind & the body as a whole system, does have long-term consequences. There are too many opinions, theories, views & not enough scientific fact to confirm whether anxiety, panic attacks, depression, OCD, etc, are pre-disposed genetically; or our biological make-up; learned behavior or if emotional or mental trauma effects the brain chemistry causing chaos…..until further progress is made & the conclusions are 100%, many of us will require anti-depressants & anti-psychotic drugs to function. I felt like I was abnormal using them at first but now, I like to think of my dose of zoloft being as necessary as my dose of thyroid meds, because without them, both my head & body suffer the consequences.

March 25, 2009 at 11:07 am
(111) cher says:

If your coming off Zoloft it should be for the right reasons, not for weight loss.
My weight appeared to be the same.

May 5, 2009 at 2:02 pm
(112) Shana says:

On 25 mg for 8 months in 2002. It relieved my anxiety but then I began to feel dulled and emotionally blunted so I weaned off (25 mg every othr day, then every 3rd day, then none). 2008–stressful events in my life, very very anxious, began 50 mg. Felt it working at day 6. Everything fine and dandy altho again the feeling of being emotionally blunted, unable to cry. Went down to 25 mg.

Started on thyroid medicine for hypothyroidism. The two together gave me a lot of side effects–diarrhea and constipation, headaches. Began taking the thyroid at 7 am and the zoloft at 7 pm. After about 2-3 weeks began sleeping 15-16-17 hours a day. No energy, always tired. I can drink an espresso and still want to sleep half an hour later. I am going to wean off zoloft again same as before, 25 mg every other day for a week, then every 3rd day and quit. Anybody else have similar side effects–the excessive daytime sleeping aka EDS?

May 6, 2009 at 3:26 pm
(113) Alyssa says:

I had been on Zoloft for about 9 months, and then I started getting very sick to my stomache when taking it, so I stopped for a month. But the drug really helps to calm me down, ease my depression, and make me less angry, so I decided to given it another shot. When I did I was vomitting all night, so I thought maybe I was just sick an waited a week to take another dose. When I took it again I became even more sick! Also when I first started taking it I had insomia for about 2 weeks! I am starting to wonder which I want to live with, my anxiety or the nausea! UGH!

May 27, 2009 at 11:05 am
(114) amy says:

I’ve been on Zoloft for almost 2 years – starting while I was pregnant at 50mg for depression. It’s one of the few you can take when pregnant, I’m told, though Celexa has worked well for me in the past. Slowly my dose was increased to 150mg. At first it seemed to be working and I felt less depressed. I experienced no weight gain, but have had TOTAL loss of sex drive – I don’t care at all about having it. Then I also had occasional dizziness. Last fall my dosage was increased to 200 mg and felt like a zombie. I decreased it t 150mg, but realized I wasn’t feeling normal. I’ve now decided to go off it completely, tapering off. Two days ago I had my last dose of 50mg, but am experiencing a lot of dizziness and a sort of out of boy experience, along with temperature spikes every 4-6 hours. I may take 50 mg every other day for the week to see if that helps, but then I want to be off it for good!

June 30, 2009 at 4:22 am
(115) betty says:

I was diagnosed with depression at the age of 12 and immediately put on Zoloft. I started out at 50mg a day. When that didn’t help, it was increased to 100mg/day. And then increased again to 150mg/day. I stayed on this drug until I was 19 when I took myself off cold-turkey. (Thank you, Jesus, I don’t have depression anymore!)

Now at the age of 24, I have very few memories from age 12 to 19. I’m now researching to see if Zoloft had any long-term memories effects.

June 30, 2009 at 5:12 am
(116) Jude says:

I started Zoloft when I was around 15 and quit cold turkey at 18. I can barely remember anything from that time, which is really disturbing.

Also I was put on Zoloft and Trazadone(sp?) which I stopped at the same time and literally thought I was going to die while going through the withdrawal. I later read that combining those meds (along with Imitrex for migraines, which I also took) can apparently kill you or screw up your system in some Major way. Way to go, doc!

At 24 I find it extremely hard to control my emotions (worse than when I was younger and prior to the meds), I can rationalize how out of proportion they are to what’s going on but they are just overwhelming, it’s to the point of being dysfunctional and hard to live with. I’m worried that taking these medications hampered my ability to control my emotions or made them change in some way.

September 20, 2009 at 2:55 pm
(117) ED says:

I have only taken Zoloft for 3 days now and already I have noticed differences. usually when I drink caffeinated beverages I am a chatterbox; not I drink coffee and energy drinks all day and am constantly tired. I have had more vivid dreams, but nothing to worry about. For the longest time I couldn’t even remember a single dream. My energy levels have plummited since I started taking it. I am less angry and less anxious, but i just feel like a zombie all day. I know it’s only three doses, but my girlfriend first noticed my lull in energy. All i want to do is sleep.

October 8, 2009 at 2:17 am
(118) Diane says:

I have been on 50 mg of Zoloft for about 8 or 9 years. 5 days ago I went to a “pain doctor” for fibromyalgia and he wanted me to try 60 mg of Cymbalta instead….sent me home with two weeks of samples….the only instructions were to “take the Cymbalta tomorrow instead of the zoloft”. So I took the Cymbalta for two days and had terrible side effects…..angry, irritable, crying, anxious, muscle aches and pains worse than ever, huge headache, insomnia….generally a nice couple of days….on the third day I was going to switch back to the zoloft….much to my family’s relief! Normally,I take it in the morning… but I woke up the morning of the third day feeling so much better that I decided not to take EITHER ONE! No Zoloft, no Cymbalta. It’s been four days now without either one, and each day I feel better. Myself again. No headache, muscle pain almost gone, sleeping better, no “bladder pain”, more energy….Wow. While I was going through the horrible couple of days I assumed it was side effects of Cymbalta….but maybe it was Zoloft withdrawals??? Does anybody know?

October 20, 2009 at 3:45 pm
(119) Matt says:

I’d love to hear some follow-ups from the people who left a single comment here and then disappeared. Don’t buy into a big anti-medicine/anti-drug conspiracy just because you may have experienced some of the negative side-effects of zoloft. And also, please bear in mind, this site does have 100 comments, but these are spanning over 2 years for a drug that millions probably take. This blog post right here references a good study that shows a very very small portion of people reported these side effects and that overall the drug is effective.


Of course, I would talk to my doctor any time I had problems…open-mindedly. Don’t go back with some kind of “medicine is out to get me” mentality and expect things to go well.

November 5, 2009 at 3:08 am
(120) John says:

I have been on half a tablet of Zoloft for about three days now. Although I can focus better and my obsessive thoughts have gone away to a certain degree, I do not feel any more cheerful now than before I started taking it, just kind of fuzzy. Another problem I am having is finishiing tasks in the bedroom, so I am going to go off of it and talk to my psychitrist about going back on Wellbutrin.

November 5, 2009 at 6:26 pm
(121) ana says:

Hi I’ve been on Zoloft 50mg for like 9 months i felt great the first time, no side effects and my anxiety and obsessive thoughts were all gone I was happy for the first time in a long time…All of a sudden I decided to stop taken it I felt ok for about 2 months about 2 weeks ago i noticed my initials symptoms of anxiety and obsessive thoughts have come back so I decided to refill my zoloft prescription ounce again I’ve been take in it for three days, and feel very unpleasent side effects especially at night, restlessness, terrible nausea, insomnia, dizziness. It is incredible to believe that the drug that gave me no side effects the first time now is making me so sick. I am going to give the drug time to kick in anyways, and just think that all that i am feeling are the side effects of zoloft and soon they will go away. You never now how your body is going to react to it for now I am going to stick with it since I am going trough a difficult time in my life and I need meds for now I know zoloft can be very effective but I would love one day could live withou it.

November 9, 2009 at 5:09 am
(122) dahlia says:

I started taking Zoloft almost one month ago for anxiety and depression. The first week I experienced severe nausea and drowsiness [which I welcomed, as I also have a hard time sleeping]. After the first week I noticed I wake up daily with a headache similar to a hangover. My migraines have come back, I am sensitive to light, and all day I have trouble organizing my thoughts and my head feels fuzzy. I am into my third week and I feel apathetic/empty. I am not depressed, but I am not very happy. I am withdrawn and very aggressive. It also has stopped by cycle for this month and I am still waiting for that. Vivid dreams as well, and I’m noticing lots of bad eating habits developing [I am a gym-rat and very health-conscious] which is causing weight gain. I want off, but the second night I didn’t take it I woke out of a horrible dream unable to breath.. worst panic attack ever.

This is causing more complications than it’s worth I think.

November 12, 2009 at 1:44 am
(123) Dee says:

I have been on Zoloft for about a year now. I just wanted to say that I was very scared to try another antianxiety/antidepressant drug because of all the side effects I have experienced with other medications. To my surprise it has helped me a lot and with none of the side effects described by other people. Infact I wasnt aware of how well it was working until I went away for the weekend and forgot it at home. My anxiety and irritability was so horrible that I couldnt wait to get back home again. I will never forget my pills again. To the people out there experiencing bad side effects from Zoloft, maybe a different type of medication would work better. Remember its a trial and error situation when dealing with antidepressants. Keep trying and hopefully some day you will find the right one. I did

November 17, 2009 at 12:58 am
(124) Barbara says:

I have taken Zoloft for about 18 months. The only side effect was having difficulty orgasming, but it has passed.
However, when winter came, I noticed depression coming back. I was already taking the max FDA recommended amount and I have always suspected I had SAD. As soon as I started light therapy, everything has been GREAT!
I am slowly lowering my Zoloft, but continuing light therapy to see what happens.
I know, I know… am I under a doctor’s care? Yes. But he doesn’t CARE what I do. Very frustrating. He has no idea what I’ve been thru.

January 15, 2010 at 2:08 am
(125) chris says:

I’m having very bad-violent dreams, while taking zoloft. I see from other comments, it’s not so uncommon =/

October 9, 2011 at 3:06 am
(126) claire says:

I am also having very bad and violent dreams, and im not taking zoloft………. bad dreams happen to everyone do they not?

January 31, 2010 at 11:57 pm
(127) jen says:

I’ve been on Zoloft 100-150 mg since the birth of my daughter 9 months ago for pp and anxiety. According to my Dr. it is supposed to be the safest anti-depressant for breastfeeding moms. It has helped me tremendously. When I have skipped a dose or two I notice immediately. I am quick to anger, frustrate easily, and can be quite mean to my husband. However, the worse part of taking Zoloft is the ZERO libido, headaches as previously described and this annoying ‘brain fog’. I have such a hard time concentrating and keeping focus. I wonder if anyone else has had this experience?
I will say that I feel soooo much better when taking this medication. And everyone in my house will agree that I am a better mother and wife. So for me, the benefits outweigh the side effects.

That said, if I wasn’t nursing my child, I would switch back to Lexapro or Celexa/Welbutrin combo.
Anti-depressants and Anti-anxitey meds are a necessary part of my life.

February 1, 2010 at 10:51 pm
(128) Renee says:

I started taking Zoloft 50mg a few weeks ago and almost immediately got a headache that would not go away. I also became very constipated, which made me feel more bitchy than I was prior to taking Zoloft. I decreased the dosage by 50% and then again 50% more, so I got down to 12.5 mg in addition to the 150mg Welbutrin 2x day. The headaches still were there so I just stopped taking it altogether. The headaches have subsided and am no longer constipated, but I feel as though I need something more than just the Welbutrin. I was on Paxil for many years until it stopped agreeing with my digestive system. Any ideas?

February 2, 2010 at 7:24 pm
(129) Valhalla says:

I have been suffering from a rather debilitating coupled Anxiety/Depression disorder since I was very young, but it worsened once I hit puberty and continually worsened over the years. I was first put on medications for it once I was 17.

I’m now 23, have been to numerous counselors, psychiatrists, psychotherapists, and been through many medications, including Effexor, Lexapro, Wellbutrin, Klonopin, and many others. The worst was Wellburtin as it gave me partial seizers (definitely a rare side effect). All of them made it impossible for me to be happy, and kept me in a morose, sometimes zombie-like state. I went to just using Ativan as needed for the panic attacks for two years, and was fed up with everything else, but I knew I needed help with the constant anxiety and depression. There was no way counseling could help because I had no triggers, I just flipped out over the most random of things.

So, I switch doctors and Zoloft was recommended. I started off at 25mg for the first week before stepping up to 50mg so that my body would be able to adjust. I take it with lunch every day, so that it’s at the same time every day and I’m taking it on a full stomach. At first it made me really jittery and I still had some minor freakouts, but on the whole it made me feel… good. I was actually able to sleep through the night without a light on and I started eating like a regular person. When I went up to 50mg, it made me nauseated, and now caffeine overwhelms my system as I have energy and started exercising on a daily basis.

It’s now three weeks into taking Zoloft, and I feel AMAZING. I’ve never been happier in my life, and my anxiety is NOWHERE near as severe. Occasionally I’ll have a panic spike, but the Ativan covers that. And honestly, having one spike of panic a week vs 4 or 5 panic attacks per week with constant panic spikes is an amazing thing. I still have a bit of nausea, but it’s more of a nuisance than a hindrance. Also, I constantly have to keep my hands busy now, but that can easily be turned into something productive.

Everyone is amazed at how well this medication has been working for me so far, and really it takes a few weeks to start working well.

If Zoloft isn’t working well for you, talk to your doctor! There’s so many other medications out there that might be a wonderful match for your personal body chemistry. It’s because everyone’s body is unique that there is such a variety of mood stabilizers out there. Also, try to eat healthy and try to get at least some exercise and some sunlight. That can also make a big difference in mood. :)

February 8, 2010 at 7:37 pm
(130) m says:

Heeeelp if anyone has experiance hair loss can you respond, This has been great for me but 9 weeks ago I was put on 100mg a day and since then I have lost 1/3 of my hair ( i know this from the width of my pony tail) the hair is falling with the root attached… does it grow back???

February 12, 2010 at 8:26 am
(131) Susan says:

M, if you recently had a baby, your hair will fall out, its normal.

Everyone else complaining o Zoloft, just tell your doctor. Maybe some of you all are experiencing a mania associated with bipolar disorder, maybe some other type of disoirder that zoloft does nothing but make it worse, just tell your doctor!

March 11, 2010 at 10:07 pm
(132) EdwardsFaveBlue says:

I have been struggling with depression for a year and finally decided to explore anti-depressants. I filled my prescription today but after reading about all the side effects, I am more afraid than ever to start taking the pills. I dont want to change, I dont want to be sick – I already have bad night sweats, if I sweat any more my husband will float away during the night. Is it worth it to not start taking the pill and continue with just therapy?

March 22, 2010 at 2:30 pm
(133) keith says:

i just started taking zoloft, i’m at 50 ml right now. i’ve only been taking it for about 4 or 5 days. last night i experienced the worst headache i’ve ever had in my life. today my leg wouldnt stop shaking, and i feel like i have restless muscles. when i got to school and tried doing my work i couldn’t concentrate at all. i don’t know what to do, but i definatly don’t want to gain any weight.

April 14, 2010 at 9:59 am
(134) shooshal says:

hi all, I just started on sertraline 2 days ago, i must be really sensitive, because i havnt really slept since. Im so tired today and cant motivate myself to do anything, this is shit, is it normal to feel this way in the begining.

April 29, 2010 at 1:05 pm
(135) EVELYN MILLER says:


May 9, 2010 at 3:49 pm
(136) T says:

I have been on zoloft for a week for depression. I take it at night and my whole body goes numb. I have headaches constantly and can’t even eat. I feel like I’m in a different world and have no motivation. I’m big into showing horses and have no desire to be near them anymore. Also I have experienced anger that I’ve never had before its really scary and went off at people for no reason that I barely knew, and reading all the previous posts I think they need to include the anger part on the warning label because I had no idea that could happen. My ex was also on this drug at one point and turned violent to me out of no where, now I understand why. Does anyone know anything about Paxil? I need to get off this drug before it wrecks me anymore.

May 16, 2010 at 2:10 pm
(137) K says:

Are there ANY positive comments for Zoloft? The feedback here is overwhelmingly negative and a lot of it sounds psychosomatic – like experiencing crazy side effects in the first two days. That must be an allergic reaction! It takes at least three weeks to get into one’s system, right? I’ve started 25 mg/day five days ago – my first time with anti-depressants, and I’m 40. I don’t feel anything different yet. But I am full of hope that this drug will somehow make me feel less sad and despondent. I’m not reading any more comments today!

June 10, 2010 at 6:05 pm
(138) Maz says:

Dear Members

I have been taking Zoloft for the last two years. Nut I have been on anti-depressent medicines for 10 years now. In these years I have taken Effixor, Prozac, etcetc and were able to tapper off from medicine successfuly, and felt like a shoplifter who gets past the security and took a moment of sigh(you have to shoplift once to understand the feeling LOL)

However, this zoloft has been the worst experience of my life. It made me suicidal, extremely irritable but at the same time provided some relied in terms of depression. At times i was bery normal and at others i was like crazy….But the depressive and non functional part of my life was corrected by ZOLOFT. I had stopped taking all interest in life, i was confused about everything, and I stopped going to work-I have never taken such decisions before in life.
However, being on Zoloft and now off it, I am giving you a sincere advice that do not use it at all. this time I feel that I have been caught doin shoplifting and now face consequences. This drug has possessed my mind, and It is making me real crazy.
I cannot take any decision, and I am so angry with people around me. i get into arguments, I beat my wife (something I had despised all my life), and I am breaking things-that is something i have never done in my life.

I am thinking of divorcing my wife, but cant make any decision. thinking of leaving the job and country but again cant make up my mind but just keep on thinking without arriving at any decision……..God help me in this situation…plz think twice b4 taking Zoloft……..

June 11, 2010 at 9:24 pm
(139) stacey2804 says:

Hi there
I have been on Zoloft for a year after being diagnosed with pnd, and have just weaned myself off 100mg down to nothing in a month. While being on Zoloft, the only side effects i have had would be tinnitus (ringing in ear) and a stiff jaw. Please, Please remember that Zoloft takes a while to settle in to your body. A good 6-8 weeks before the nausea/insomnia/sleeplessness settles. Week by week, i felt slowly, but surely, that i was getting better. And then, well after 6 months i went back to my doc and he said that it sounds like i need a little longer. I was concerned that i had hit a plateau and would stay the way i was. Ok, but not better. However, after another six months i have finally done it. I felt myself that i was truly ready and made the decision. The last month hasn’t been easy. I have had a sore stomach and i am very short with my kids and husband, however i am hoping this will pass. I find this the easy part when i think back to the visions of people dying, my children dying and myself dying that Zoloft has helped me overcome. I was obsessed with death prior to Zoloft. My tinnitus has disappeared, although while weaning myself i had the head tremors (brain zaps) and was worried they were going to be permanent, which they weren’t and i also had a vibrating eardrum which i’m not sure was an effect of coming off Zoloft or just my cold i also have. Please don’t be put off trying Zoloft, it has worked for me, it may not be for everybody but if it works then it is well worth trying!!

June 29, 2010 at 2:35 am
(140) fabulousone says:

Wow. Reading all the comments….is both helpful and interesting. I want to say a few things…First of all, 50 milligrams of zoloft is not even a therapeutic dose. 100 is barely therapeutic. I was on 200 mg. a day for the past ten years. It worked when I needed it, and now it is time to stop. About two months ago, I began to taper my doses, sometimes not taking them at all. I’ve been completely off it for about a month now, and am feeling better than ever. It amazes me that a doctor would leave someone at such a small dose, that literally has no therapeutic value….not to mention the side effects, and for what again???? If you are on less than 100 mg., I would contact a psychiatrist and talk to them about what is a therapeutic dose and what is not. I had some severe withdrawl symptoms, but I made it through. I won’t go back on zoloft again. It has run its course and I’m nearing 47. Finding inner peace is helping me, meditation, reading, doing things I enjoy…exercising. I’m on estrogen, and that’s all I want to HAVE to take anymore. I have noticed that I am sleeping better, dealing with panic better, and not as afraid and paranoid as I was when taking zoloft. Wow, what a difference! I wish everyone here the best of luck, antidepressants can help, but only in therapeutic doses! And they don’t just work on their own…you gotta do the work and get some therapy IN COMBINATION with the drugs. There is light at the end of the tunnel.

September 2, 2010 at 8:51 pm
(141) Sherrie says:

This is my first week on Zoloft, the only side effects I’ve had so far are nausea and being a little bit shaky. Hopefully these will pass.
Apart from my stomach feeling terrible, my moods have improved greatly, I can now find the motivation to actually get out of bed in the morning and I feel happier.

I read that it’s bad to drink coffee when you’re on Zoloft for anxiety but I’m on it for depression, is it still bad?

September 5, 2010 at 9:30 am
(142) penny says:

When I first met my boyfriend he was recently off Zoloft and I immediately recognised there was an issue of some description because he was so “twitchy”. I thought he was abusing Panadeine Forte for the Codeine, or worse. When I learned he was withdrawing from Zoloft it made sense. Then he recently re-started it…this was obvious to me without being told because he became aggressive, short-fused, poorly impulse-controlled, as if he was completely without feeling or empathy and like he had a wall around him that was impenetrable by me. He has become someone I no longer know, and I feel that although I love him, I am not so sure I like him anaymore. He has disrespected me and disregarded my feelings too often, yet before he went back on the Zoloft (for more energy, lift his mood and to get him through his work on the farm) he was loving and certainly a kinder human being. He has stopped saying he loves me and his personality has changed from the time the Zoloft started to reach its peak in his system,. With him now increasing his dose again I feel I have lost him. I think he feels bomb-proof. But what about those who love him?

October 10, 2010 at 9:38 am
(143) minnie says:

I have taken Zoloft on and off for years, just last week I went cold turkey because I want to get my health in order and try the path of better nutrition, I don’t want to be on drugs anymore! I feel better already.
I felt I was becoming addicted to sugar and couldn’t control my constant craving for chocolate and cola, so much so that I was hiding cans around the house. Couldn’t think straight, very indecisive, moody, irrational, argumentative and full of rage.
I also suffer Hyperthyroidism / weight loss / skin rashes and severe short term memory loss – haven’t read a book in ages because as soon as I close it I’d not be able to elaborate on what I’d just read, very annoying! I can’t say that all the above symptoms are from Zoloft, I’ve never had a great memory and my skin rash surfaced when I wasn’t taking Zoloft so it’s hard to know what triggered what.
I know it’s hard to watch what you eat when some (bad) foods can be the only thing you look forward to in life but I am currently on a Gluten and wheat free diet, which helps and I drink lots of purified water (buy the best water purifier you can afford!) There are a few great books worth reading if you want to work on better nutrition for your mind – Patrick Holford’s “New Optimum Nutrition for the Mind” was a revelation – look into natural supplements such as DHA Oils (I don’t eat fish but you can now get veggie DHA capsules) also 5-HTP and SAMe supplements may help as well as Lecithin, Hemp Oil, Extra Virgin Coconut Oil, Ghee etc.

October 10, 2010 at 9:41 am
(144) minnie says:

PART 2 – (WOW! 2000 characters can fly by!)
A good read “Brain Allergies” By William Philpott. Your Doctor probably won’t tell you about the connection between nutrition and your state of mind, he/she is paid to alleviate your SYMPTOMS not to find the cause. Also, most Dr’s get ZERO training in nutrition, maybe 2 days at best…so don’t take their word as gospel, you have to become a detective! Search the internet for things like “Orthomolecular Psychiatry” buy organic wherever possible, avoid processed foods, especially trans -fats. Get your blood or hair checked for heavy metal toxicity – I have a mouth FULL of toxic amalgam fillings – if I was to so much as spit on the sidewalk it would be illegal!

October 10, 2010 at 9:43 am
(145) minnie says:

PART 3…..
I watched Stephen Fry’s “The Secret Life of a Manic Depressive” (3 times) before I recognized that I probably had Bipolar II and not just depression. Most people with Bipolar are diagnosed (wrongly) with depression because you only go to get help when you are down not when you are up, also, thyroid issues can cause bipolar like symptoms….
So, before you take Zoloft just read up about bi-polar and ensure you don’t have that, otherwise SSRI’s may make you hyper at times…(not all that bad if you have spent months not caring whether you live or die!) I am grateful that it gave me the opportunity to be creative once again, and remember what it was like to enjoy something.
For me, I can feel the effects of Zoloft after only one hour, but it feels “fake” as if I’ve had a mild dose of ecstasy but if you are desperate enough I totally understand why you’d want to try it, or try ANYTHING just get out of your own head for a while.
Also, it may sound weird but try to have some relaxation time for yourself, if you can muster the energy join a yoga class, get centred or spiritual so you will be in a better position to see the bigger picture. Don’t forget to Exercise and be sure to get some sunshine! avoid watching depressing / crappy TV, especially the news!
Take control as much as you can and remember that no-one can care more about your health and wellbeing than you.
If you must, use Zoloft as the British Unemployment Benefit was meant to be used, as a net to catch you when you fall.

November 20, 2010 at 9:06 pm
(146) chris says:

I have taken zoloft for ten years. No issues ,I’ve worked up
to 200 mg per day, I take before bed time. I sleep like a baby, also I use a c-pap. I have sleep issues and always
have had morning sleepieness even with the c-pap. Sleep
studies revealed 92 interuptions per minute thus the cpap,
and also a day time sleep study showed falling asleep in 60
seconds. I now take providgle tofix that. All is well, although I don’t know what life would be without it.
None of the side effects as described other than those of
a sexual nature. I’m 57 so who cares. And if i have to a viagra or cialis takes care of business. It also has a great
response on my adult adhd. It saved me on that issue,
otherwise I’m bouncing off of walls.

November 22, 2010 at 11:38 am
(147) Nick says:

I was started on Zoloft for my anger issues. Doc started me out at 25mg. It seemed as though i was getting ammune so Doc boosted it up to 50mg. Now my body feels as though its covered in fiberglass. Easier to understand is like after you have a haircut and that loose hair falls in to your shirt, yeah that annoying feeling. Now picture that from head to toe.

November 24, 2010 at 5:14 pm
(148) Kacey says:

I’ve been taking Zoloft (50mg) for 3 days now and I already feel different. My doctor prescribed it for anxiety and panic attacks that I’ve been having. I have been feeling a bit out of sorts, almost not myself. At times I feel worse and sick, then other times I feel happy and carefree. My puplis are heavily dilated, which isn’t a huge problem, but it’s noticeable. I hope that the sick feelings subside within the next few weeks, I’m going to continue taking it like the doctor told me. I feel dizzy as well, does anyone else feel like I am feeling?

December 12, 2010 at 3:15 am
(149) jose snovi says:

my wife just went on zoloft, im scared, when we met she found alot of things “pretty” she enjoyed the simple things, especially nature. i miss her. im hoping it really helps right now she is mad at everything i do, , i guess she is just mad at the world, im not a perfect husband by anymeans but some of the things i have done i really dont feel I diserve the retrepution i have gotten from her, she is angry, sometimes hatefull, i have found that sometimes i hide things from her now that would anger her just so she doenst have something else to yell about, all in all im hoping zoloft helps, not sure how much longer i can take of her “hateing me” like i said im not perfect by anymeans but im not that bad i dont think. anyway i dont feel it can get much worse. we have a wonderful daughter we both love but my wife insists i am emplieing she is a bad mother, wich cannot be further fro m the truth, everything i say is not negative but she takes it that way i dont know what to do

December 12, 2010 at 8:50 pm
(150) Karen says:

When my husband started Zoloft – it was like a wonder drug . . I had not seen this side of him for 30 years, he was so up and happy. After a couple months . . it started to reverse until this point (after five months) he is right back to where he started. Angry, paranoid, very depressed . . . and he was only on 50mg – when they tried to increase it he had a ‘dream’ – although he explained it was SO real, he could feel and taste things – it was a very VIVID and disturbing dream that left him very shaken.

So . . I guess taper off of Zoloft. He has tried so many other ADs . . I’m not sure what the next step is. He has a wonderful psychologist he sees – so at least he has that (and me!).

December 13, 2010 at 9:50 pm
(151) Erin says:

Anti-depressants are still a mystery as they do not help everyone. I think they should only be used in the most sever cases and only after other things like therapy, family support and other aid has been done.
I had severe clinical-depression for seven years and it got so bad that I became suicidal and had no hope. I am a very fortunate person who has a wonderful life and nothing to be sad about, but it just started to hurt to live. I cared about nothing and ached all the time. I cried and cried and was just miserable. I finally got help and started Zoloft. I have been on it for a couple months and it has actually been very helpful.
The first month was awful, I actually was more depressed and anxious, had insomnia and severe tremors and got even more suicidal. Thankfully, through support of my family I got through it and once I got to about the sixth or seventh week (when it takes its full effect) I felt normal. It feels wonderful to be normal. Even though I still have stress and get down it is not depression or anxiety. I sleep again and I am overall happy and content. The only problem I have now is I get nauseous. Oh, and I actually lost weight. Gaining it back now, but once finals are over I’ll be eating less. (I eat more carbs when stressed).

I encourage those who are in severe cases to try it and know that you can get better. It sucks, but its like any other disease where it takes times to heal and find the right medicine. Remember, try getting therapy and talking it out first along with exercise and taking breaks. If it doesn’t help then an anti-depressant may be for you.

January 10, 2011 at 3:31 pm
(152) Tony says:

Well just started zolfot on thursday the 6th havent noticed any diffrence in anything yet no stomach problems no sleeping problems nothing well it is only 25 mg now i go up to 50 this thursday wonder if its going to make much of a diffrence.. So can any one tell me how long it takes for this stuff to work?? i know that most pills dissolve in 30 45 min and is in your system and doing its job well what about this stuff. I guess ill see soon.. drop me line if you know ant thing else i should know???

January 26, 2011 at 11:03 am
(153) Nadia says:

Hello everyone. Zoloft for me has been great. I had severe depression and suicidal thoughts. This has been the only medication that has helped me. I feel much better, am motivated and it has also helped me with social anxiety. My side effects in the beginning were diarrhea(embarrased), a feeling of anxiousness, and sleepiness. Once I got used to the medication, it no longer had those effects on me. I did not gain weight and overall I am a much happier and more relaxed person. This drug is not for everyone, but it has helped me alot.

February 14, 2011 at 6:07 pm
(154) aje says:

i have been taking zoloft for a week now, at 1st 50 mg, but i was tooo dizzy ,now im taking 25 mg , i feel sick/vomity, still having panic attacks and i am still dizzy. i ve been toild to stick it out i will get better what does anyone else think

February 22, 2011 at 7:27 pm
(155) Dante says:

hello everyone i just started sertraline 50mg and im not sure if this is really what i need…. i havent been feeling good in the past 2 years i have been light headed on and off and feels like my head is racing and my heart beats realy fast at times…. sometimes i get theese attacks out of no where…. where my hands get like cold and tingly and i cant breath right i feel verry week like almost passing out…. im not a depressed person and yes there is alot going on in my life but everyone has problems…. im 24 yeard old and im not active anymore doing sports and things because of all this mess…. if any one has answeres please let me no

February 23, 2011 at 2:35 pm
(156) Danielle says:

This drug for some is something..I cant even feel this drug in me..why i dont know i still feel the same as i did 2 years ago.,With the passing of 5 family members in one mouth..I needed help and i still feel the same way my doc up the meds and i to have gain..Im lost and i feel there is no help.

April 1, 2011 at 3:44 pm
(157) Audrey says:

Hi Barbara… Citalopram is an anti-anxiety medication.. The generic for Zoloft is Sertraline…

I have been on Zoloft 150mg for the last 5 years with great results.. When people say they are having these side effects, is it really a side effect or is it your anxiety/depression/ocd/ptsd causing the problems…

Okay here is my issue… even with the given great results, I am having breakthrough anxiety, not as bad I try to bio-feedback myself… my dr. told me it isnt working for me as well, and put me on ativan as well.. Im wondering if maybe up my dosage some more to see if that may help.. I have been under alot of stress lately, and I know that plays a roll on anxiety.. Anyone with experience? I dont want to have to change my medication…Please let me know. Thanks

April 19, 2011 at 4:29 pm
(158) Lil Darlin says:

Having been on Zoloft for about 15 years now, I’ve seen it all, heard it all and experienced very little of it. Zoloft has been very, very good to me. My Drs. had me start taking it because of the Major Depression I was experiencing with chronic and severe migraines (pain and depression go hand-in-hand), while they continued to do tests for the migraines.
It was ultimately determined that the depression was here to stay, as were the migraines (a bone spur growing inward in the neck vertebrae) and Zoloft eventually hit 200mg.. With 200mg. being the top dosage and the anxiety factor starting to weigh in, rather than try another med (which would require weeks of withdrawal followed by weeks of build-up . . .UGH!) my GP consulted with my Psychologist and they had me taper down to 150mg. on the Zoloft and added 20mg. Geodon . . .this was about 6 years ago and it still works like a champ!
Check with your Doc . . .

April 22, 2011 at 3:18 pm
(159) Steve says:

I was prescribed Zoloft a little over a week ago for anxiety and I seem to be one of those unlucky few who do not tolerate it well. Although my dose was only 25mg, after 5 days I began feeling worse than I ever have in my life–and I’ve had kidney stones, food poisoning, colitis and other unfortunate episodes. I’ve been waking up about after an hour’s sleep (at most), sweating profusely, gripped by panic, wracked by tremors, esp. in my legs, nauseous, and feeling like I’m going to jump out of my skin. Worst of all has been the sense of hopelessness. I have perhaps been suffering some mildly depressive symptoms these last few months, but nothing like this–like William Styron’s name for depression, “darkness visible.” .My psychiatrist has been very responsive and concerned, and he took me off it immediately. But even though it’s been over 36 hours since I’ve had a pill, I am still feeling very sick and am praying that the side effects taper off soon. I have some pretty serious responsibilities at work, not to mention two young kids, and I’ve been close to incapacitated by this drug. Thank God I have such a supportive wife and that my wonderful parents happen to be in town.

I also have faith that I WILL feel better soon and will
address my anxiety by other means.

One other thing to mention–I took Xanax and then Ativan (on different nights) hoping it would break the panic. But a good friend of mine who is a psychiatrist let me know that these drugs are designed for normal anxiety attacks, not the SSRI-induced panic I was suffering. So no help there, I’m afraid.

I share all this not to rubbish Zoloft; I believe that it has helped many people and that I am in a minority who react so badly to it. But I do hope that others can perhaps have some company in their misery, and that I also have hope that I will improve. And I’d be grateful if they were to share similar stories about how long it took for symptoms like mine to disappear.

May 5, 2011 at 11:14 pm
(160) dee says:

I took zoloft about 4 years ago and it worked. It worked well and pulled me out of my depression. I slowly worked myself off of it by cutting down to half dose for a couple weeks then every other day and then nothing. And I was back to “normal” and never had to take it again.

I just started taking it again about 5 days ago and it does make some changes. I definitely have trouble sleeping the first week or so. I wake up around 4 or 5 no matter what. that usually happens when I drink too. I never drink when on ssri’s cause it would just make it worse.

I also feel my jaw a bit more tense and have more intense dreams and for some reason get songs stuck in my head lately. I also have lower libido.

So yeah, there are side effects, but the sleeping gets a bit more normal after awhile and the dreams mellow out a bit too. And it works for me.

So definitely give it a couple weeks and see how you feel. It’s not for everyone but there are definitely people who have good experiences with it. I’m def one of them.

May 24, 2011 at 4:13 pm
(161) Nia says:

I have only been taking the 50mg generic Zoloft for a week, & I don’t recall sleeping a full night since I started… Will this wear off? Should I switch anti-depressants now? Help!

May 24, 2011 at 4:59 pm
(162) Jacinta says:

I have taken Zoloft for 3 1/2 years. It hasn’t been perfect in controlling my anxiety, but i has helped a lot. The initial side effects sucked. Im now finding 3 years on that I can’t help but sweat, even in the middle of winter, I sweat. Apparently its from the meds…

June 11, 2011 at 9:26 pm
(163) youngandscared says:

I am 17 and have started Zoloft this year for depression and anxiety. My depression did not improve so my doctor increased the dose to the maximum 200mg. I actually had an increase in depression and for the first time in my life had suicidal thoughts. I was literally scared for my life.

I am now going off Zoloft, but it is slow process. I have extremely vivid dreams that scare me to death when I wake up.

Zoloft is not even FDA approved for children under 18, so i have no idea why this scary and very powerful drug was prescribed to me. I am so young and I now have to deal with the scars of nearly commiting suicide for the rest of my life. Adolescents SHOULD NOT be taking this drug. I will do everything in my power to pass legislation to protect children perscribed anti-depressants, because no one so young should have to go through this. I am hurt and broken from this drug. Please help me in my efforts to help others!

June 26, 2011 at 5:24 pm
(164) Betty says:

I started taking Paxil in 1999 because I was having severe panic attacks and went about a month where I could not sleep. I took the Paxil for about 3 years and changed to Zoloft because of weight gain. I took the lowest dosage once daily. I then asked my Dr to prescribe the Zoloft and he gave me 50 mg. I take 1/2 every other day and I like my life now. I am able to sing in church in front of crowds and not get nervous and do not have panic attacks any more. My life is so much better now. Things do not bother me as much as they used to. I think everyone that needs an antidepressant just needs to find the right dosage for them. I do not want to stop taking the med because i feel like a different person than when I didn’t take it.

July 14, 2011 at 10:32 pm
(165) Roger says:

I was having big time anxiety attacks and benzos were doing great. Bu they are supposedly for short time use. I start zoloft at 25 mg, the up to 50 , then 75.

By the time I wa at 100mg, I was insane. I stayed up 24 hours had a grand mal seizure at work, went to the hosptal, and felt electrified with energy. That night I took 4 ambien throughout the night and slept about an hour. I got out of bed with sun, and my body felt as it it had the DT’s. But my mind was unusauly calm—-I was a trembling wrck though.

And my heart was pounding the entire time.

I weaned off of it and am so glad, it was hell for me.

But, its great for some. My friend said Keppra made him run into the street nude, screaming. Keppra has been awesome for me. But my trial with the ssri’s is Over.

I’ll risk addiction—its all a cost/benefit analysis.

July 28, 2011 at 5:47 am
(166) Anne says:

First off this a longcomment but please read. I have agoraphobia and mild depression before zoloft i was taking welbutrin but i just switced to zoloft 100mg today. I took it in the morning around 10 and around 2:30- 3:00 I started feeling really nauseous so i had my mom pick me up cause my house was way too hot whchi thought was the reason even though usually i can stand the heat I started breathing real hard then and had to lay down i could barely walk i was so weak and my hands were gettng tingly and i was shaking as if i was like cold or something i went to go lay down and drink some water and ventually i got my breathing undercontrol and i wasnt shaking too much but all my musces felt sorta like they were twitching and they were all tense and they just wouldnt relax when i got uo to get some medicine for my head and chest cause they were hurting and tried to eat but my jaw wouldn stop shaking and i couldnt realy chew then i started breathing really hard and everything felt heavy and stiff and it was hard to move I started shaking alot has anyone else had anything like this i know ive onlybeen on itfor one day but should i just stop takin it

August 17, 2011 at 10:25 am
(167) Will says:

I am naturally a high strung person and have been taking it for a couple years. It has gotten me through some tough times. But on a negative note, I feel like I’m living in a fog, and life is passing me by. I can’t seem to snap out of it. I want to stop taking it so I can have that zest for life again. But i don’t want to go back to the anxieties.

September 3, 2011 at 8:34 pm
(168) Selma says:

I have been taking Zoloft for 3 years now. I first started taking it in 2002 after giving birth to my beautiful daughter. I was on 50mg for about 6 months than took myself of it. I had mo side effects getting on or off.
The secobd time I started taking Zoloft was in 2006 after giving birth to my second daughter. The side effects were so severe that at times I just wanted to end my life, but the dr. kept telling me to b storng and stay calm. Staying calm was impossible as anxiety was present every day, trambling, shaking, panicing, not sleeping and trying to take care of two small children. Husband was useless as he kept saying to snap out of it every time I callapsed. This lasted 4 weeks and I was so happy it did.
In 2009 I was getting really depressed so my Dr. increased the dose to 100mg. Same stupid side effects but I held in there cos I knew that in a months time I would be a s new.
I was on 100mg for about a year and I have no idea what hapened that year at all, it felt like I was on speed or something, my mind was racing 100km an hr and I was so inpatient, so I decided to cut down to 50mg. I did thid slowly and I only had mild side effects for few days. I did take Valium and it helped.
Now I have another problem, cos 50mg has been working well all this time I thought I’d be a tough cookie and decrease my dosage to 25mg. It was all fine for about 5 days than anxiety kicked in and I knew I had stuffed up cos my body obviously is used to 50mg and only functions on tha dose. So I ut myself back on 50mg and now I am experiencing those horrible side effects. I take half a Vallium of 5mls 4 times a day cos without it I couldn’t function. The Valium just helps a bit, but I must say I hate this feeling… Does anyone feel tha same?

October 3, 2011 at 2:49 am
(169) ashley says:

I was prescribed 100mg zoloft for anxiety, panic attacks, stress, and irritability. When the pharmacist told me that 100mg is quite a bit for someone who has never taken it before and that most people only start with 25 or 50mg, I decided to just take half. I have been taking it for 4 days now and I took it at night like the pharmacist suggested. So far, these are the side effects I’ve experienced: my mind races a million miles a minute at night and feels like it’s going to fry which causes more anxiety and panic attacks, I feel like I dropped acid the night before because I constantly keep having this euphoric state of mind and being, my hands started trembling really bad one time, I got dizzy and almost passed out last night, YAWN YAWN YAWN omg the yawning makes me want to put a bullet in my head, headaches, crazy dreams, and negative thoughts (I keep thinking my mom and my boyfriend are annoyed with me or something but I think it’s just the zoloft making me perceive it that way). I can’t imagine how I would feel if I actually took 100mg of this stuff! What scares me most is that I have 3-month-old twins and a 3-year-old to take care of and I feel like I have an afterglow (a state of being experienced following a “trip”), I’m tired, and I can barely function. How is this sh*t legal?!

December 15, 2011 at 11:57 pm
(170) Mike says:

I had depression and anxiety for a long time. I started taking zoloft in college and the day i started it i vomited and have had diarhea everyday since. Its been about 3 months. It also made me extremely angry. My temper got a lot worse. I would scream and yell at my parents and i tried to fight anyone that looked at me wrong. Not to mention all the doors and walls i punched. I then started concerta( and ADD/ADHD drug) and it helped immensely. I found that my problem was i couldnt stop my mind from racing all the time. Now im on 100mgs of zoloft and 28mgs of concerta, but im trying to get off the zoloft. I never felt any less depressed. But the concerta helps me deal with everything.

January 9, 2012 at 4:18 am
(171) kate says:

I am going back onto Zoloft for the third time. First time was for about a year after college – minimal side effects and it really helped me a lot.
Second time was after a panic attack and severe work stresses and it also helped a great deal – dealing with work and difficult people became so much easier. (Although for about a week, I slept only about 2 hours per night until I adjusted to it)
This is the 3rd time around, day 8 – feeling much more functional and motivated, constant need to cry has pretty much gone, which makes conversations with my colleagues and my partner much easier. A bit drowsy though, and need a mid afternoon nap, which is funny given that last time it was insomnia.
I really feel that this was the right choice for me – if your doctor is reputable and they prescribed this to you, it may really help you out.

January 9, 2012 at 6:51 am
(172) dawnmarie says:

I am only on 50mg but i had no side.effects beyond being tired the first week. I do have vivid dreams and they tend to be a bit draining but not so bad i’m willing to give up all the good it’s done for me.

January 19, 2012 at 9:10 pm
(173) Crystal says:

I agree that there are more negative than positive comments here. I just looked at another site that had only positive comments. These are really biased and I have had no problems and everyone’s experience is different.

January 30, 2012 at 7:08 pm
(174) Deanna says:

I also noticed alot of negative comments but they mostly seem to be from people I think are really Bi-polar and not just suffering from anxiety or depression. In the side effects it does state that Zoloft may increase the manic side of Bi-Polar and even make the person more agressive. If they have Bi-polar they also need to take a mood stabilizer.
So far my only side effect is ringing in the ears which is hard to completely blame on the Zoloft because I have tinninitis, it just made it worse at times.

February 13, 2012 at 6:18 pm
(175) sissy says:

ok i have some really bizarre experiences to share. i was on zoloft for exactly a year and a half, not for depression but for extreme anxiety. during the time i was on it, my side effects were: the really strange dreams! (but they are just dreams, i didnt let them bother me.) of course, absoutely NO LIBIDO (i will get to that one in a minute.) those were the two negative things. also, although it certainly helped with my anxiety and panic attacks, i felt very “flat” emotionally. neither high nor low, not sad, not mad, but not happy either. one really odd thing i noticed was that my “motor skills” were better. for instance, if i dropped something, (i know this will sound SO strange) i could grab and catch it before it hit the ground. toothpaste, makeup, a cup, whatever. i know it was the zoloft because now that i am off it, i am back to being a klutz and cant catch anything! and one thing has def happened: i have not had ONE panic attack since the moment i went off it. now the bad side effects THAT ARE STILL WITH ME, after being off of the drug for five years: my sex drive NEVER came back. and before zoloft i had a very healthy sex drive, my entire life, well into my 50s. but it has never returned. one more thing: you know how some days you just feel happy to be alive? for now reason, just might be walking down the street and suddenly you feel very grateful, and very happy. i call it “joyous”. well, my joy (and my sex drive) have been permanently erased, and know one seems to know what to do to help me. has ANYONE experienced these side effects?

February 29, 2012 at 10:43 am
(176) Liea says:

I’m currently taking 1/2 the 50mg of Zoloft, and after going through other medications for my depression and panic attacks thus far I like Zoloft better normally within the first week I get the craziest side effects. I do have vivid dreams, that I don’t mind, I do care that now I can go out in the world and feel normal.

March 7, 2012 at 1:02 am
(177) William says:

I understand all of the feelings…I have been on Zoloft for over 4 yrs. now. I started with 50MG was up to 200MG for two yrs. I asked the doctor and he cut it down to 100MG for the last year…I ran out last week and didn’t go get a refill in an effort to retrieve my LOST libido. I want to feel like a man again. I also have Type 2 diabetes and that doesn’t help. Now however I feel like and emotional Jello-mold. I cry, I’m paranoid (not that some one is out to get me) If some one doesn’t talk to me…I did something to make that person mad at me. Sex…Drive is there, Equipment doesn’t want to work. Feel like 50 going on 75. Want to be ME again.

March 21, 2012 at 5:41 am
(178) Kiena says:

I have taken almost every psycho med on the market. So far Lexapro was the best. I could actually sleep on Lexapro. HATED Paxil,Wellllbtrin,Effexor,and Immiptramine. I was diagnose at 25 with Bi Polar. I’m now 40. Lexapro worked for a few years then it just stopped working. I am now kn Zoloft 100 Mg. I feel ok but I cannot sleep. I was told by my Dr. ThatvI must remain on medicine. I am also on Buspirone because all of the Sari…help depression but increase anxieties in most people. My 3 children are 21,18 and 16. My oldest is my daughter and whenn she moved out I was a mess. My middle son.is leaving for college in August and I know this is going to be hard for me. I KNOW I HAVE YO LET GO. My youngest son started driving and I am starting to realize Empty Nest Syndrome is gonna hit me hard. I sometimes think because I was a stay at home mom for15 years that I put myself totally into my kids and now I’m lost.Thanks for listening…..

April 1, 2012 at 7:36 pm
(179) Kristi says:

I have been on zoloft for a week now. First couple of days I took half a pill (25mg) and I noticed that I was having a real hard time going to sleep. I do have anxiety/depression so I figured maybe that is what was going on. After taking it for a week Today I moved up to 50mg and I feel terrible. My head hurts and I feel like I took a ton of cold medicine. My stomach hurts and I was about to go into a full blown panic attack earlier. I have always been scared to try meds and now finally I am on one and it is making me feel so sick right now. I don’t know if I should stick it out or just stop taking it.

April 2, 2012 at 2:07 pm
(180) pinkoats says:

Zoloft doesn’t MAKE you gain weight. At least, not everybody. Sometimes it changes people’s moods and habits, which includes eating and exercise habits and choices. I’ve stayed vigilant with mine, and have never experienced weight gain on 100mg.

May 3, 2012 at 11:26 am
(181) SHANNON says:

Was just prescribed Zoloft for panic attacks, after reading these im not going to take it. I take care of my 2 babies all day and cant see myself dealing with these side affects while doing so. I think im just gonna deal with the occasional panic attack! Thank you all for sharing your experiences!

May 6, 2012 at 4:54 pm
(182) Donald says:

I have been taking Zoloft for about a year now and I do not like it. It does not have the calming effect that I felt on Prozac. Plus, what is worse is that I am starting to have moderate to severe leg pain in my calves and hamstrings. I don’t sleep as well on Zoloft. I know each drug effects everyone differently but for me Zoloft is not worth taking anymore. I am gonna call my doctor and see if he can get me on something else.

June 1, 2012 at 2:56 pm
(183) Imelda says:

I have been experiencing Nervessness, fear and withdrawn from life. Started on Zoloft almost a month ago but I still dont feel being me. Started on 25 then 50 then 100mg and that caused me to panic and have Anxity every morning. Went back to 50 but still not feeling me. Does this ever go away? I feel as I am never going to be me. Feels as if I dont’ have control of my life.

June 5, 2012 at 3:21 pm
(184) Peter says:

I am on zoloft now for 10 years on and off. I suffered a heart attack 3 years ago and today i am worse than ever. panic attacks won’t go away. i feel like I am choking at times. I have seen many doctors. no one has been able to help me. I am sick Of switching drugs and the wait and see attitude of the pscys.. Help

June 6, 2012 at 6:11 pm
(185) Dutchie53 says:

I have read every single perons problems here on this site. I suffer from being a manic depression person as well as bi-polar, and diabetic. I took Zoloft for several months, to several years, off and on as those quark doctors told me to take it, and I became so mean my family told me I had better change the medication. I went to one of those genetric drugs, that was no better. I aslo had weird dreams that bothered me all the next day. I took a good look in the mirror and did not recognize the person in the mirror. I did not like myself or that person or my life. I had shut down-completely! It took my Mother, who has a degree in mental health to carry my load for several years. I happened to get on line and ran into a sight for herbals. So after reading all of the info, I re-read it again. Next day after failing all meds, and my diabetes out of havoc, I threw ALL my meds away and have never looked back. I started taking herbals, and in one months time, everyone had noticed a HUGH change in me. Hell even my diabetes was where it should be. I am happy and have a normal life, or what is “normal”? Yes I had to exercise to get my weight back down, but I found as I simply walked. I could air out my problems, and think clearly again, in the meantime I had walked four miles, and never missed a beat. Yes, there are still some very low problems in my life, but if you work though them one at a time, and you have to think positive, and prayer works too, I am much better then I was in 2004. Being a Zombie, and Hateful does not get it in life. Medications we take now were never meant to be in our bodies. I do have to stay away from fats, junk foods, sodas, and some meats. I eat from the earth now. Ever wonder how indians made it? Good luck to you all!

June 25, 2012 at 8:19 pm
(186) Celena says:

I have been taking Zoloft. I have gain waight ,somet times feel like killing my self can,t sleep heart beats fast picking scabs because it feels good…

July 5, 2012 at 3:14 pm
(187) Steve says:

I have been taking Sertraline (Zoloft) for a week after switching from Citalopram (Celexa). I hate it, I feel angry all the time and my anxiety has come back. Doctor switched me because of the sexual side effects of Citalopram but now I just want the peace I had on that drug back, so am going to ask to go back.

July 15, 2012 at 2:44 am
(188) anna says:

My brother died 3 days ago and is on zoloft.. He commited suicide.. He seemed
The last few days .. do you think its a side effect.. He just started taking it last month

July 21, 2012 at 10:51 pm
(189) carly says:

im 27 with three kids i have been dealing with panic attacks for a year straight i fear leaving my town an when i leave i feel like i cant breath and i feel jittery and tight in the stomach i started of on 25 mlgs of zoloft went up to 50 and just 5 days ago went up to 100 mlgs so far i feel ok been on this med for a year now but still dont wanna go far, does anyone out there know what im going thru couse i just fear it wont get better

July 29, 2012 at 11:23 pm
(190) Susan says:

I am so tired. I have been on zoloft for five days and I feel like a zombie. I can’t think straight. I have no reaction to things that are funny. I have severe mental fog. Most of this seemed to have happened after my dose went up to 50mg from 25mg. I also notice afer upping the dose, I am eating less. On 25mg, I was super hungry. I really hope this will subside because, I don’t know if I can take these side affects. I am a teacher and I have no idea if I will be able to do my job effectively feeling this way.

August 1, 2012 at 3:37 pm
(191) stacey says:

Please help. Trying to find out if anyon else might have the side effect of memory loss. A 15 year old girl a told me she have been forgetting alot more and her mom won’t believe her.
I askd the mom and she said the doctor said that is not one of the side effects. I notice it can be on the site just not one everyone get.
Please let me know.

September 8, 2012 at 12:03 pm
(192) James Bond 007 says:

Let me tell you something people, at time the f$%king tablets works and sometimes it dosen’t. I have so much anger at time I does feel to kill people and can’t tolerate them. I feel that I’m going mad here. When taking the F$%king thing and when stop taking it, the withdrawal effects are deathtrimental.

September 24, 2012 at 4:49 pm
(193) joanna says:

glad im not the only one with brain zaps ive been on sertraline 100mg for a yr im hopless at taking tablets i take one when i start to get brain zaps which is usually after 3 days latley ive noticed im very tired and dont care feel withdrawn and cant concentrate i also feel weak and faint as anyone else had this ive always been energetic but i just feel rubbish at moment discussed with doctor he asked me if i felt better in my mind and ready to have my dose lowered to get off them but in all honestly i dont know how i feel any one else in same situation ?

September 30, 2012 at 10:31 am
(194) Mel says:

I have been on zoloft for about 18 years because I was so depressed I was suicidal. I was at one time up to 225mg., but I am down to 150, trying to get down to 100. I think they overuse this drup. If you have bipolar II or depression, it really helps. I didn’t gain weight from zoloft, and I didn’t get aggitated. It worked great for me, but after a lot of good couselling I’m feeling like I want to get off of it. This week I am going to try going down to 100 again. I tried it a few weeks ago and I had to go back up.I was on lithium for 10 years and I have been off of that for 6 months. I’m doing this all under a doctors care. I felt like a zombie for most of the time I was on lithium and the higher dose of zoloft, but it helped me with the depression and I was able to work for most of my life, without it I do not think I could have done it.

October 9, 2012 at 12:46 am
(195) Colby says:

I hate Zoloft. I feel awful on it. 2nd night in a row to not get 1 hr of sleep. Tried taking Xanax to help knock me out, but no luck. Experiencing gastrointestinal aches, as well. Not really sure when to take this…! I take it at night right now. Hoping that should change. College football player trying to survive here!

November 23, 2012 at 5:35 am
(196) Finola says:

I too have experienced severe weight gain with these tablets. The thing is, the more weight gain the more depressed I feel. I have gained at least two stone in 5 months, despite restricting my intake on food. It’s making me want to stop taking the tablets but I did that a while ago and it made me realize how much I need them. So, I’m a bit stuck, as I’ve researched and most antidepressants have a side effect of weight gain… I’m on 50mg and I feel I need something stronger, as the depression and anxiety is still there every single day.

November 24, 2012 at 11:03 am
(197) Mike says:

Getting the dose right is critical. My doctor gave me a 50 mg script and it is about 10x too much. Everybody has a different ratio of neurotransmitters and you need to change the right chemicals and not all of them. It does not seem as useful for panic attacks as it does for depression, avoidant personality disorder, and similar complaints.

It does turn off my libido and causes enough mental fogginess to make work difficult, but I’m semi-retired now. I only take it two or three times a year

December 1, 2012 at 6:00 pm
(198) anaby says:

Look guys I don’t take any drugs anymore ,just a quick fix or I say a cover up of whats going on in reality how earth does a pill do all these thing to help ..not ! I’ve been reading the Choice theory William Glasser,M.D. Fantastic read good for my health mental and physical.it’s WARNING: PSYCHIATRY CAN BE HAZARDOUS TOTO YOUR MENTAL HEALTH. yes the only winners in taking Zoloft are the doctors fees after diagnose 20 minute fee and the drug companies. really it is true I deal with sad and stress a lot differently today and it’s all good for me no dam side effects.. other books are CHOICE THEORY AND REALITY THEORY …. BEST OF LUCK TO YOU ALL SINCERELY .

December 8, 2012 at 2:56 pm
(199) melissa says:

I just look up the side affects for zoloft 25mg and i have been taking them for little aover a month i feel a little stress angry anxiious butt still on the edge.no side affect some i feel like they dont work att allll what do i do

January 28, 2013 at 5:54 am
(200) Leigh says:


February 1, 2013 at 1:39 am
(201) Victoria says:

I went from 25 mg. to 100 almost overnight. I have no libido, feel fat, am angry and hateful and can’t see my shrink til’ Valentine’s day. She is impossible to reach and also won’t give me adderall rx, last filled over a month ago, until my appt.. All I ever get is answering service and a snarky little wimp and my messages aren’t taken seriously. What the hell should I do? My arms ache and hands hurt which may or may not be a side effect.I’m angry and alone and no one seems to care, though I come from a family of suicide victims.

March 17, 2013 at 4:06 pm
(202) nick says:

my coment is too bob my wife started taking zoloft with my knowledge and with in a week the police were chasing me down for an order off protection now im putt out of my house my life and my step kids who are my kids if you know what im mean i love her and forgive her but she totaly bared faulse witness if you know what i mean this drug sucks stay off it and keep it away from friends and family god bless smoke ganja indica for pain sstiva for depression make sure yoi know what is what exsp if ypu are going to use it for depression

March 18, 2013 at 10:59 am
(203) mary says:

Jan I finally read a side effect of zoloft that I have also, thought I was the only with night sweats, bad dreams and burning in legs it is horrible

March 26, 2013 at 3:23 am
(204) marianne says:

I have been on Zoloft for about 6 months. My temper is managed, but my memory is frightening. Called my sister today to tell her some news, she said I called her 15 minutes ago with same news. This is of some concern.

April 7, 2013 at 3:28 pm
(205) tt says:

what are the SIDE EFFECTS!

May 6, 2013 at 3:42 pm
(206) Susan says:

You have to give Zoloft a month to work properly. It makes things worse the first month, then things smooth out. But the first month is unbearable and no one should try it without also taking 2 ativan a day, on in the morning and one in the afternoon. Then stop taking the ativan after the first month because it will become habit forming if you take it longer than that.

That is how you stay comfortable while waiting for the Zoloft to work.
I did well on Zoloft but I did experience the sexual side effects. I took “honeymoon weekends” where I wouldn’t take it and was able to be “OK” during those two days of not taking it.

The biggest problem was that it affected my memory. I took it for about 3 years and have stopped now for about 6 years. But my memory is still pretty bad, especially my short term memory. I think my dosage was probably too high. I think that 200mg for someone who is 110 lbs is too much and it probably fried my brain a bit.

Also, if you are pregnant I advise to not take this if possible, or take a very small dose, because I did and my daughter now has autism. The weird thing is that now she has terrible anxiety and I would put her on Zoloft except for I worry about the memory side effect. Perhaps she would be fine on a very small dose. But now the drug that perhaps caused her to have anxiety and autism, is the one I am thinking about putting her on…ironic isn’t it?

But as much as there is the “dark side” to this drug, it pulled me out of a very scary time. I was very, very sick with crippling and painful anxiety that came on suddenly. It got me back to feeling OK after a scary first month. So I do owe something to this drug. I was in a hole, and it brought me out. But look how I had to pay…probably not worth it since my daughter has autism.

August 11, 2013 at 9:57 pm
(207) jean says:

I suffered from extreme panic disorder which led to agoraphobia beginning in my late 20′s until it reached a point in early 30′s that I had to seek help. One of the things that cause my panic attacks was taking medication so avoided going to dr for years knowing they would recommend medication. Started by opening the capsule , emptying medicine and gradually leaving a little bit more medicine until taking 25mg then increased to 50mg in about a month. Had a little increased anxiety in the first week but when you’re having panic attacks constantly a little more anxiety short term is not a big deal. Took in the mornings so it didn’t affect my sleep. Only effect I had was increased social life, able to function with my family /kids and became independent. Was many months before making a noticeable difference but then continued to 3 years. Stopped taking it after 3 years with no side effects and remained “normal” for approx. 8 years and now finding myself again starting with panic attacks. Just about to start taking Zoloft again and hoping to have the same great results and relief.

August 22, 2013 at 4:50 pm
(208) Jnenny says:

Just wondering if anyone that has taken zoloft and has had experienced worse depression or any bad side effects that others have list, also have any kinds of sleep disorders or sleep problems?

August 24, 2013 at 10:27 am
(209) Alice says:

I am 20 years old and have been dealing with the great combination of OCD, PTSD, Depression, Anxiety and Panic Attacks. I finally decided to turn to medication once i realized the past 7 years of therapy didn’t do a thing for me.
First night i took Zoloft 50mg i woke up 5 hours later throwing up and releasing anything that was in my stomach. The next night, i took it again, woke up 5 hours later with a horrible panic attack and twitches all over my body (mainly calves, fingers, neck, eye). My panic attack, which included: Throwing up, crying, pleading for safety, tremors, irrational thoughts, BP about 150s over 90s, lasted from about 2:30am to about 8am.
I had not had a panic attack in 4 months until i took Zoloft. i stopped after the second time, when my mom honestly asked me if i was going through a herion withdrawal after seeing me act like that for so long. it was the most intense panic attack i have ever felt in my life. it has been a few days since then, i have been able to keep anything down and i am constantly nauseous.
My doctor now prescribed me xanax and unless i take .25mg my body aches, i am throwing up, or i am clenching my stomach due to the pain of hunger and cramps.
Any tips? this college kid could really use some before fall semester starts!
Thanks (:

March 18, 2014 at 1:21 pm
(210) Rebekah says:

I am 25 and was diagnosed with a Major Depressive Disorder at 18. I have been on many anti-depressants since–Prozac, Wellbutrin, Lexapro, and Cymbalta. Cymbalta was the only anti-depressant I was happy with. It was like a miracle drug. I felt like a new person.

In January, I found out I was pregnant, and immediately made an appointment with my psychiatrist, who switched me from Cymbalta to Zoloft. I have been on Zoloft about 2 and a half months now. My mood is stable, but the side effects are just too hard to deal with. I am CONSTANTLY nauseous, tired, and unmotivated, and I often get terrible headaches. At first, I thought this was because I was pregnant, but after skipping my Zoloft for three days (which made me VERY sick, I don’t recommend doing that to anyone) and then starting again (which, I assume means, there wasn’t as much Zoloft in my body, because it had passed its half life) I felt absolutely fine! Cheerful, energetic, my old self.

I think I probably need a lower dose of Zoloft (I’m taking 75 mg now) so I have called my psychiatrist again. If I need to, I will try to wean off of it because I can’t deal with these side effects. They have started to affect my job performance and I have lost 3 pounds from being unable to keep anything down. If I continue losing weight, it won’t good for the baby, now that I’ve entered my second trimester. Hopefully, a lower dose will work.

March 20, 2014 at 1:52 pm
(211) Elizabeth says:

I am about to turn 23 and have been on anti-depressants (Zoloft) since I was 15 years old. I originally started at 25mg and increased to 50mg when my Mom died. Then, I got put in a treatment facility and had to be increased to 100mg. This is a terrible drug with awful side effects. I am now having brain fog, decreased concentration, and I fear I will be on it for the rest of my life. Don’t take this if you don’t have to and feel you can survive without it.

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