Effexor XR and Memory Loss

My memory is going out the window. I am having trouble remembering things from yesterday, granted I haven’t always been the best to remember things. I have noticed that I am forgetting tasks at work, this has never happened. I find myself using an entire pad of sticky notes, and forgetting to complete the notes written.

Hello, yes, I’ve been taking Effexor as well, since last November, and I’ve been having memory problems. Even yesterday I can barely remember. It’s so difficult. But I am also glad that someone else is experiecing this. Usually, I had a good memory but now it has gone down hill.

yesssss! i’ve been on it for about 9 months, and the SAME thing is happening to me. i forget things daily, lose things often, and my attention span is like a 3 year old boy. my doctor also told me theyre not connected, but i KNOW they are, which is the main reason i’m coming off the drug now. i wishi would have been informed of all this before i got hooked on the stinking drug.

I have been experiencing memory loss for awhie also. I started taking Effexor spring 2005. Before that I had been taking Zoloft, which was not working for my anxiety and depression. I notice about 3-6 months into taking Effexor that my short term memory was playing tricks on me and the more I think about it the more I realize this drug has something to do with that. What should we do now? Does anyone else think we should be contacting the company and find out the truth about this being a side effect???

I have been on Effexor for about 2 years now. It has worked better for me than Zoloft, Celexa, Lexapro. The drawbacks for me is the profuse sweating and the memory loss/confusion. I can get the medicine out, take it, and within a few minutes I can’t remember if I ever actually took it. I use one of the daily medicine organizers now. It helps although I can carry the medicine into another room in a napkin and if I don’t take it right then, I have been known to throw the medicine(in the napkin) into the trash. Memory disturbances and profuse sweating are the worst on Effexor, but it has been the best to control anxiety/depression for me. So for right now, I am just dealing with the side effects.

I have taken Effexor XR for quite a few years; the exact number of years I cannot remember. Every time I have complained about the memory loss; the inability to concentrate; and the instances of not being able to remember how to complete tasks at home and at work (that I have done hundreds of times), my doctor tells me the depression is to blame. I don’t know what to believe. I take three different medications for depression; have completed intensive therapy; I do not feel depressed; and I do not exhibit any other symptoms of depression. I know the Effexor has killed my energy level and the higher the doses I take, the less energy I have. This is another way I do not feel like my “old self.” Before taking any antidepressants, I was like the Energizer Bunny. I could go and go and go. The doctor’s “fix” was to add another antidepressant, Wellbutrin, to try to counter act the anti energy effect of the Effexor. I suffer from fibromyalgia which can mess with a person’s thought process, and I am going through “the change” which can also cause memory loss and confusion. I do know the fibromyalgia, the extreme hot flashes and profuse sweating, and the switch from Paxil to Effexor all happened at about the same time. The posts on this subject now have me wondering how much of what I experience is because of the Effexor. A few months ago I saw an attorney’s commercial about Effexor. I can’t remember the attorney’s name, but I do remember the commercial saying something about people who take Effexor should contact that attorney. I wasn’t paying much attention until I heard the voiceover say Effexor, and I’ve only seen the commercial once so I haven’t been able to write any of the info down. Maybe the memory loss and confusion has something to do with the attorney’s commercial.

I have only been on Effexor Xr for about 2 months and have been experiencing the same symptoms. I know I dont have the greatest memory in the world but have noticed a significant decrease since I have been on this medication. I can’t remember words I want to say when I am conversating and when doing tasks or about to do tasks I often have to stop and think about what I am doing or what I was about to do because I dont remember. I would also like to say that this medication has greatly helped with my depression. So much better then Paxil or Prozac. But I am also concerned about when I will have to stop taking it. I recently went away for a weekend and forgot to take the medicine for a few days. That Monday afternoon I was crying non-stop about everything. And then, later that evening I was contemplating suicide when for the time I have been on this medicine I had been doing great and was generally ALL the time up-beat. So, that was kind of scarey. I have remembered every day since to take it and am scared to forget to take it.

Thank you all so much for leaving your comments. I have been on Effexor XR for a number of years and have always made excuses for my memory loss, but of late the memory loss is more severe than ever before. I too have been thinking it is from the Effexor. Sometimes the things I forget are so out of character that I am stunned by the reality.
I have been in psychotherapy 2xs a week for over a year to get to the bottom of why I was depressed. We are at the point now of looking at decreasing the medication with the cooperation of the psychiatrist overseeing the process.
To those of you thinking of going of anti-depressants either cold turkey or outside of therapy, take it from my past mistakes at doing such a thing — it became a worse depression than ever because I hadn’t dealt with the deep underlying issues that caused me to be depressed.
Thanks again for your comments.

I have taken Effexor for several years and until recently it completely eliminated the depression. However, recently, the memory lapses and the attention deficiency has become a great concern to me. I have an extremely successful, though high-pressure, career that I have begun to feel could be threatened if I don’t resolve this problem. I’ve given up the medication a few times with disastrous results, but I sure wish I could find a happy medium. Were it not for the effect of my symptoms on my family, I would almost prefer the depression to the side effects.

What puzzles me is that I took Effexor for years without this side effect.

i came across this posting with a search for ‘effexor memory’ because i wanted to see if others have had the short term memory problems i have been coping with. i’m curious to know what dosages you folks are taking to see if there is a correlation. i’m currently taking 225mg of XR. it has really been a tremendous drug in terms of my depression so i would be hesitant to switch to something else, but man is the memory issue frustrating.

I have been on effexor for 4 months. My memory loss is getting worse by the week. I have trouble thinking and concentrating. When in conversations with others I often can’t think of the right words. I used to be an energizer bunny as well but know find myself tired and my mind dull. I noticed after 2 weeks how stupid I seemed and now its worse. I can’t remember what I am sopposed to be doing and look blankly into air all the time.

yes I have been on the med for about 2 years, and my memory is really getting bad and I wondered if it might be the effexor

I am 56 and just joked that I have early-onset Alzheimer’s. But I found a website that has a petition on it of people complaining about the withdrawal symptoms, and I saw that others have had memory loss and fogginess, as well. It’s http://www.petitiononline.com/mod_perl/signed.cgi?effexor&1

I told my doctor that I couldn’t understand because I used to make straight A’s in HS and college and now I feel lucky to be able to figure out things that would have been simple before.

This is very scary for me. I am 26 and experiencing almost every side-effect! i can barely make a sentence without forgetting the point of it.I am on 75mg of xr a day.Whats even worse is that i am going threw this and my mom just got put on the medication this week and she is already experiencing memory and energy problems> I am paralized w/fear!!

absolutely!! I took
effexor XR for several years; 350mg daily dose-have lost complete chunks of memory. Along with serious sweating and elevated blood pressure. Finally made the switch to Cymbalta 60 mg dose. Memory is better, sweating much less and blood pressure normal.
It seems to have the same effect but without side effects of
Effexor.

ive been on effexor about 2 months and am forgetting things like to take my keys, and i keep forgetting doctor’s appointments etc. Ive always been excellent at remembering these kinds of things. I think my memory is mush

I have been on 300 mg effexor for about 3 years now. I have noticed that my memory has gone to the dogs. I can’t remember simple recipes that I knew at the top of my head and have trouble putting things together. I have gained a lot of weight since on this drug (I was a small person once). I am now trying to get off this med (replacing with wellbutrin) but the withdrawls are hell. I have been on other antidepressants in the past but the withdrawls were never like this. I am constantly crying, my mind is racing, I have vertigo, I hear swooshing noices in my head when I turn my head or move my eyes, I could go on and on but this could take all day. I don’t know what is in this stuff but I want off really badly…..the way I am feeling right now with these withdrawls though, I don’t know if I can. Would not recommend this to anyone.

Reading everyone else’s comments have really helped me to undrestand where my memory loss problem has come from. I was on effexor xr for maybe six months a couple of years ago, and started having memory problems. I went off the medication and just recently decided to try it again, but now I definitely will not be trying it again. I don’t believe the memory loss is temporary, as I’ve been off the medicine two years and I am still having major problems with memory loss over simple things. I also experienced consistent headaches, disconnected feeling, and vision problems.

I have been on effexor for almost 1 year and I have experienced a lot of memory loss to the point it is interfering with my job and family. My doctor also told me that there has been no evidence to say they are related but after reading all these comments I believe they are.

I took a large range of anti-depressants, for varying periods of time, including Effexor, which is one of the ones I took for a longer period. And I certainly have had memory problems since the depression started.

But I am not at all sure it is due to the meds, and not somehow the result of a whole range of processors going on in the brain – i.e., a symptom of the depression and its aftermath, rather than of the treatment.

In any case, I would bet that while you will find lots of reports of memory problems by people on Effexor, you would also find such reports from people on other anti-depressants – so switching from Effexor would not seem to be the answer.

Yes- I too have had what seems like memory loss– but may be the ability “to let go” a bit more instead of trying to be responsible for remembering a gazzillion more items that one really needs to. I take a very small does of Effexor, and have noticed this with other medications as well.

I had a more or less photographic memory before I started this medication. For a long time I thought that the memory loss and concentration problems were the result of the depression and anxiety (as the expensive psychiatrist told me!). The reasons for both are gone and they themselves are much better, which makes the memory loss and lack of concentration much more noticeable. I’ve had to stop work because of them. I am now certain they are caused by the drugs. Thanks to everyone for responding to this post – why are all of the doctors so resistant to the idea that the drugs may be causing the problem?

I am in the long, nasty process of withdrawing from Effexor after about three years of up to 300 mg. Now at 75 mg, I have been gleefully remembering things that I would not have remembered when on my full dose. Like others commenting here, when I complained to my shrink that my memory and concentration impairment were amounting to an intellectual disability affecting my work and other functioning, he told me it was the depression, not the Effexor. Interestingly, I wasn’t feeling depressed. Now that the haze is clearing, I strongly suspect he was wrong.

Reading everyone’s comments makes me feel both relieved and scared. It is clear that there is a connection between memory loss and Effexor. I have to say that I have done great being on the drug with the exception of memory loss. It is feaking me out. I’m forgetting so many things at work that I normally would not have forgotten in the past. I guess my big question is…once you get off Effexor, does the memory come back or get better?

Thank the Universe for the internet!!! I was beginning to think I was crazy! This Effexor has damaged my memory as well. It stopped the racing thoughts and ruined my memory! I’d rather race.
Thanks to everyone who posted here. My dose was only 37.5mg a day, A non-theraputic dose according to the doctor. Thanks again,

I’ve been doing some research concerning the side
effects of effexor xr: memory loss. The good news, because there’s always good news, is that it may NOT be memory loss but rather CONFUSION CAUSED BY LOW SODIUM LEVELS IN THE BLOOD!!!
My next step is to tell the Dr. to order a blood test to check the sodium level in my blood. I’ll let you know what happens. After checking the side effects listed by the manufacturer (low sodium levels and confusion are just two of the side effects) and looking up the medical definition of “confusion”,
it makes sense to me to have the sodium level checked. I am determined to get off this drug and get my normal OCD-self back! Ain’t no drug out there gonna get the best of me! Don’t let it get the best of you either. Jessica

Gosh, that’s how I found this site. I feel like a moron…I have/had a successful career, but since starting Effexor, my memory has really caused my problems. I have taken many other meds, but this has never happened. I am only taking 75mg…was taking 150, but had too much anxiety. I have been taking it for nearly a year. I thought maybe it was just aging, but I”m only 36. I don;t like feeling like this! Please repost about the sodium!

My memory, concentration, etc is also much worse than it used to be. 300mg/day for maybe 3 (or 4?) years – less than the first year was spent ramping up to the full dose. While we wait on the sodium results, here’s another thought:

Our brains are constantly sorting through all the information that comes in and deciding what to discard and what should go to your memory. There is an anti-anxiety part of Effexor that helps us all care a little less about everything (for better or worse). What if this effect extends to that mental sorting process? As the mind sorts the information, it disregards much more of it than it used to which leaves much less to be stored in memory. This would explain why others on anti-anxiety meds would see the same thing, but it doesn’t quite explain why the effects would last after going off the drug. Unless…

Argh – my mind’s starting to race – must be time to go to bed :\

Anyone else have have muscle twitching in their neck? But not actually twitching – it’s more like what happens if you have something stuck in your throat, and you’re trying to unstick it. Only I don’t have control of the muscle contractions like I would if there was actually something stuck there (which, of course, there isn’t).

Good luck to all, and happy dreams

My mother was on Effexor XR for who-knows-how-long. Years. Her memory and ability to process thoughts is severely impaired. She often gets hung up thinking of words to say mid-sentence. And she seems incapable of learning new things.

For example, she likes watching movies on the VCR. She can’t remember how to turn on the TV, how to play a tape. She asks me for help. So I patiently show her what to do. The next night, she’s back to square one, not remembering how to do it. Actually, often I’ll after showing her how to turn on the TV (a one button exercise) and wait 5 minutes, she won’t remember how to do it. Pretty scary stuff.

Anyway, with the assistance of a doc, she tapered off Effexor, and hasn’t been on it for about 2-3 months. In some regard her cognitive skills are improving, and in fact her interest in life is improving (so much for effexor being effective), but her memory is still not, and her cognitive skills still have a long way to go.

My questions are these: Does anyone have experience with how long it will take to regain what she’s lost, and what can we do to help it along?

The situation is pretty desperate. She’s fairly unanble to take care of herself. Also, since coming off Effexor, she has at least gained the self-awareness to notice that she must ask how to use the VCR everyday (just one example of what she’s having problems doing in life), which makes her feel stupid, and scares her

Also, in the thread, Chris said “My doctor also told me that there has been no evidence to say (Effexor and memory loss) are related.” Aside from these posts and simlar posts on the internet, I’d ask the doctor, “what evidence do you have that they are not related?”

Also, you all may want to read the book America Fooled. Here’s a link…
http://www.americafooled.com/

On effexor two years for cyclothymia. Worked like magic from day 1. Bad withdrawal headaches if I even miss a few hours taking medication. Memory issues started in first month. First visual imagery (minds eye, imagination) shut down. For example I was unable to visualize a face and have the name pop up. This effectively restricted the way I access my one-time encyclopaedic memory which was effectively indexed visually. (Subnote- this is probably why effexor is rated the highest antidepressant for causing sexual dysfunction because without the imagery/fantasy it’s just friction.)
Short term memory slowly deteriorated over the last two years to the point it is affecting my work and family. I was seriously thinking alzheimers till I read this page. Thanks

I’m sure there’s a connection. I am making uncharacteriscally stupid mistakes at work over and over and can’t stay on top of tracking thinga. I’ve taken Zoloft, Serzone and Wellbutrin before and never had this problem, only stopped the Zoloft and Serzone because they lost effectiveness at treating my symptoms after taking them for a long time. Effexor XR was added to my Rx for Welbutrin, so it’s not from coming off Wellbutrin – has to be the Effexor. I’ve been wondering if it isn’t some kind of drug interaction between the two. It’s a relief to find out that I’m not the only person experiencing these symptoms. I can’t continue to take this drug – I’m going to lose my job if I do.

Thank you all for making me feel normal again!

The other day I was talking to one person when it was, in fact, another person…but I didnt realise until it was pointed out.

When i write my letters are all over the place. sometimes i cannot spell simple words. I forget to go to work and University. I forget yesterday, the day before, my childhood. This is madness.

I need to get off it.

I’m reporting it to the Pharmacist. We must all do it!

Im So Glad I Came Accross this important info about EFFEXOR XR. I’VE been taking 300mg for 3yrs. I’ve Had Forgetfullness Eversince! I Too Asked My Docter If It Was Aside Affect, And He Too Blamed It On Depression.well I Believe Its The Drug Thats Responceable For My Forgetfullness And Thanx Too This Website I Realy No For Sure That Its Not All Phsycologicle.

I’ve been taking Effexor for about 6 years and have noticed a gradual but significant decline in my ability to learn and remember, and not age related. Long term memory is fine, but since returning to university full-time I’ve had nothing but low marks and frustrated instructors who can’t understand why I performed so fabulously in my undergrad but fail so miserably in my graduate studies. I’ve found interesting data to support the fact that serotonin directly affects the hippocampus (where many memories are stored) along with areas of the brain involved in thinking and personality. However, no one REALLY knows for sure the effects of these anti-depressants because they influence SO many areas of the brain and because the research isn’t easy. The only thing we can do is try to use non-medicinal strategies to cope as best as we can and use as little medication as possible. AND, let’s pray that someone doesn’t discover that those who take effexor or similar meds. are more likely to have dementia in their old age!

hey everybody, after reading all this I realise that my memory problem and the difficulty i have to learn new things (im taking the Bar exam right now and its really a big problem)is definitly due to Effexor. i was on effexor and wellbutrin for about 1 year in 2001, i havent taken any medication since! and yet i still have a hard time remembering trivial things! i need to get my memory and concentration level up and running again a.s.a.p. so that i can complete my studies, what should i do?? any suggestions?

Hi all – I am 69 and have been on Effexor for about 6 months. Lately I am starting to forget what I was going to say – if that makes any sense. I am glad I have read this site and will now look into going off Effexor. I was very worried it could have been alzeimers.

Jo

Jo

I did suspect it was the effexor but this just confirms it! As my dose has increased so has the confusion and memory loss. Surfing the web has to be one of the most frustrating things as no sooner than i’ve thought of somthing I want to look at, i’ve forgotton it again and just end up staring at the google homepage wondering what to type! Also I was doing an online memory card game with my 2 year old son. He whizzed through it while I was still trying to get the cogs to start turning! On the plus side I have realised that I have actually forgotton to worry about things i normally would have. So it’s not all bad, as frustrating as it is! Another embarrasing problem is paying for stuff in shops using coins. I just can’t seem to get my head around counting them out so they add up to the right amount. Now I either use notes or stick to plastic!

I am sorry to see these messages. It’s permanent. I’m sorry that it was my choice to use effexor many years ago. Vision and memory probs.

In reading all these comments, I am glad to know I have a great doctor. He DID tell me that Effexor could be the reason I can’t remember things. The problem is, I need the Effexor, it works for me, but at what cost? My 91 year old grandmother and I are on the same level when it comes to remembering names and what happened yesterday.

Geez, I’ve been on Effexor for a few years now – and even though it has helped my anxiety (started when my son went in the Marines) I seem to forget ALOT. At first I thought maybe it was due to the stress – but I’m so forgetful now – I realize there is a problem. Memory problems are showing up in every aspect of my life. I feel like the gal that was going to stay home and pay her bills and wound up starting a dozen different projects, never finishing one – and never got around to doing the bills either. I need a ‘to do’ list in just about everything I do now – mostly at work. I’ve always pride myself on the responsibilites I had at work and how others could count on me for the answers – well it’s mighty scarey for me when someone calls – and I can’t remember where I placed invoices, payroll forms, tracking schedules. Glad to find this blog – thought I was going crazy. I’ll see the Dr. the beginning of the year to get off this med. Just hope it’s not too late – and the effects are not permanent.

I’ve found a lot of people who are experiencing this problem, but few who know if it’s permanent, how long it lasts after discontinuation of drug, and how to help bring the memory up to normal levels…

Does anybody here have info along those lines?

I have been on Effexor XR for about 3 years now – 225 mg at the highest dose. My memory and attention got so bad that my dr. put me on Strattera, which didn’t help. I am now taking Ritalin 20 mg and am weaning myself off Effexor without my dr’s knowledge. I divide a 150 mg capsule into three parts, so I’m averaging 50 mg/day (not bothering to measure). I feel more alive than I have in a long time – I think my memory is a bit better, but I still forget stuff that should stick with me better. I’ve warned people not to let their drs put them on this drug! There’s other meds that will help with depression and anxiety, without all the problems later on.

thank you thank you thank you…I am a pharmacy tech and have been on effexor xr 75 for about 2 yrs, the other day my husband finally broke down and told me i’v become a ditz since being on this and he wanted me to see if it was the med…same results, i did research at work and talked to rph and md and all said probably age(30) or night shift work, but now i know for sure my husband is right, im scared to go off it because it works so well, but i have 2 kids who need me to be on the ball..paxil made me gain weight like carzy so im nervous about other meds, ive finally lost the weight and dont want it back…i think ill contact the mfr of it,too and let them know this is a real problem.again thank you for making me feel a little less nuts!

Thanks for posting your stories…I have been taking 75mg/day of Effexor XR for one year and just in the past three months have noticed that my memory is gone, one day to the next. Once I’m reminded it comes back to me but it has been affecting both my family and my work. Please tell your doctors and pharmacists. This is serious! Anyone recover after stopping the med? I stopped taking it for about four days over vacation and starting feeling really agitated and bummed out. How has anyone done withdrawing from this?

Yes! I too have been suffering memory loss. It is when I typed in “Effexor Memory Loss” that I found this site!

I will soon be weaning off this medication and I am anxious to see if my memory improves.

I’ve been on Effexor for about 8 months. It has alleviated my anxiety symptoms completely, which I love! However, now I have trouble paying bills on time, remembering to buy groceries/supplies for the house (even remembering to write down what I need), and most importantly, remembering where I put things! I’m so afraid of the anxiety returning that I don’t want to go off of Effexor, but maybe a lower dose would help?

Ohhhhh, another frantic soul who typed ‘effexor-memory loss’ into google. Of course it has to be these drugs, we get nothing for free in this life and it seems we have to make a bargain with the devil when it comes to anti depressents. I too do not suffer from depression as such any more but like many others of you have a really responsible job and kids and I am a single parent. Heck I want to play at super mum and I give it the best shot, believe, but I am becomming an embarrasment to myself. I keep buying DVD’s that my kids tell me we already have, i watch a film and see it brand new and then am told we went to the cinema to see it last year. People tell me really personal and profound information and I forget what it was almost straight away, there is a limit to how many times you can ask someone to remind you about something you were honoured to be told in the first place. So many people think its elective forgetfulness, this is so frustrating because it drives me to distraction. I go to meetings and have to give reports, the amount of times I say ‘I cant remember the name/ the amount of money/the place etc I feel like a numbskull. Even reading through these comments I have to reel myself back into focusing on what i am reading and why. I so relate to the person that says they type in google then cant remember what important thing they were going to look for! I also find a differnt manifestation of OCD in that because I cant remember things and it drives me bonkers I spend hours going through the alphabet to remember names etc. Bonkers before, bonkers now but in a different way! But would I trade it in and have the depression back…. nope.

I am going thru a very ruff time. I thought I was having a stroke. My doctor started weaning me off of Cymbalta and onto Effexor Xr. I lost my memeory, scared my adult children to death, they finnally hauled me off to the hospital. The nurse at the counter kept asking if I needed a wheel chair. I was confused, weak, had periods of shortness of breath, periods of heart palptations, dizzy to the maximum, the room was not spinning it was me, and is still a periodical event.
The hospital hooked me up for an EKG, CT scan of my head, xrays of my chest, tons of blood work and an extra vile just incase they needed it laying on the counter, started an IV, they were all hopping around like I was dying. Thankfully “all” my test came back normal, just great, the doc said. Right now I am shaking so bad I can’t concentrate. They only thing they can tell me is drug withdrawl from the Cymbalta to the Effexor and a drug reaction to the Effoexor. This will last 7 to 14 days. It debilitated me. I couldn’t work drive or function normally. I still have up to 7 days to go. I had to return to work to be able to pay for the doctor bills and the rent.
Memory loss! I couldn’t remember my childrens names, and at times had to look twice to see for sure if it was my child. Thank you for the info from all of you. I sometimes feel like people think I’m making things up. Thank you.

I took Effexor XR (300 mg daily) from beginning of 2002 until approximately September of 2004 for severe anxiety AND NOT depression. Effexor seemed to work great for the anxiety unless one factors in the severe jaw clenching resulting in 3 broken molars. There were many other issues but the ability to deal with social activities and less crippling panic attacks seemed to outweigh those side effects. That was until I had an “incident” and suffered from a complete blackout. That was in April of 2003 and the blackout and other issues that soon became evident were blamed on everything else but Effexor. I thought I had been slipped the date rape drug GHB. People seemed to be able to believe that as more probable than a sudden reaction to Effexor but my memory had gotten so bad that I, like others I’ve now read about, couldn’t function without a notepad in my hand to remind me what I was doing at any given time along with extensive use of email “drafts” and calendar items. Regardless, I came across similar complaints at RXList and decided to wean off of Effexor at the end of summer 2004 ( I had lost medical coverage so this was unsupervised and not recommended!). THAT is when the deep depression started, and remained for almost 2 years! I took nothing other than Xanax occasionally and just bit the bullet. I returned to my reclusive, but safe life, and within months I noticed my short term memory returning slowly. The depression was terrible and I was suicidal (without action) for much of that subsequent 2 year period and felt trapped. Through web research, I started on mega doses of concentrated fish oil, and for about a year, 5-HTP. I don’t know if 5-HTP helped but it certainly didn’t hurt. I have no doubt that the concentrated fish oils (Omega 3) saved my life. It wasn’t until after about a year of being off of Effexor that I realized that I had lost great big gobs of long term memory as well as that started to come back though the time I was on Effexor is still a fog. I still take lots of supplements but again, I attribute my recovered memory and escape from terrible depression to the fish oils and I will never stop those. I’m still a terribly anxious individual and socially phobic but I’ve decided that I’d rather live with those issues than to loose my memory again. Being technical minded in nature, the loss of my memory and focus were detrimental to my career and I’ve yet to recover from that loss. I stressed the lack of depression in the beginning of this reply to make it known that obviously, depression isn’t the only thing that contributes to memory loss since I wasn’t a depressed individual until I went through Effexor withdrawal. Maybe it is just my browser but why does this string seem to start May 2, 2006? The original post ID is #7358 posted June 14th, 2003. Maybe if others are only seeing posts from May 2nd 2006 through today, they should hit:
{http://forums.about.com/n/pfx/forum.aspx?msg=7358.1&nav=messages&webtag=ab-depression&redirCnt=1} drop the proceeding and ending brackets! Good luck to all with your lost memory!

I was on effexor for aproximately 6 months and eventually weaned myself off of them. I started at 75 and went to 150. I had severe memory loss, I would have conversations and not remember what I myself said, which of course really messed up friendships & work, I would get in the car and not remember where I was going etc. I tried to stop taking it cold turkey but that was a mistake as the electric shock sensation in my head was unbearable. I took the 75 and reduced the meds in the capsule to be aproximately 25 or less. I did this for about 2 weeks and kept reducing the amount in the capsules. This was the only way for me to get off this medication without too much damage. Too bad my Dr. did not warn me about all the side effects, I think they should take it off the market, or they should change the name to soul stealer because I really did not care one bit what happend to me or anyone else around me when I was fully on it. This is a dangerous drug.

I took Effexor several years ago and it affected my memory terribly! If someone asked me what I had done 5 min. before hand, I could remember. Even though it’s been several years ago since I took it (I’m on Wellbutrin now) I still have memory loss and it’s not gotten any better. It has affected my ability to do my work and I’m only 36! I got on the internet today just to look for information regarding this issue!

CORRECTION FROM MY LAST STATEMENT: I meant to say I COULDN’T remember 5 mins. before hand!

I’ve been taking 300mg a day for 7 years and 150mg a day for 2 years before that. I lived a full year with extremely painful depression before realizing I could get chemical help.Counseling for emotional trauma simply was not enough for me.During my depressed year I was in a constant stupor,exhausted,and could not remember things short term. After a year of this a doctor put me on Welbuteran which gave no change. Then we tried Effexor XR, gradually increasing to 150mg a day after 4 months.I began feeling myself again except for being tired a lot and having poor memory. .After taking 150mg a day for a full year my energy and memory returned.For me depression wreeked havoc on my mind and body which took time to return to normal. I was feeling so normal that I stopped taking effexor and relapsed into depression for 3 month’s. I had to go on 300mg a day to return to a good state again and I’ve fine ever since Every body is different. There may be thousands on effexor who have no memory problems.Metabolism is so different in people.Hang in there and go easy.

I am 19 years old and have been taking Effexor XR for 7 years. I was on 35.7 mg a very low dosage until this year. I also take 400mg of Lamictal a day for Bipolar disorder. however this year I increased my Effexor dosage to 75mg a day because i experienced a family crisis. I had extreme symptoms when i first increased my dosage. I did not eat for two whole weeks and had insomnia for 3 months. Nothing could put me to sleep. which stopped when I had an anaphalitic reaction to antibiotics and then a very bad flu with in a week of each other.
since my increase in Effexor I’ve noticed how out of it I have been. Frequently I forget something I’m saying in the middle of a sentence. If I don’t write something down I will not remember it. I cannot remember names and frequently confuse people. It is getting embaressing.
Everyone keeps telling me I have ADD because I can’t focus on anythin.
I feel like I am living in my own world. My friends continually comment on how I’m such a space cadet. One of my friends parents even asked if I have taken lots of drugs and that is why I’m so spacey.
It is deffinatly affecting my academic life as well. I have difficulty remembering anything I read or discuss in class, and it has made it very difficult to write papers and take tests.
I also have difficulty remembering the right words. I previously had an extensive vocabulary and now I find myself using simple words over and over again because I just can not remember more complicated words.
I had a severe concussion a year ago and thought maybe this was due that, but then I realized that I had recovered from that probably 6 to 8 months ago. and that this memory loss and confusion has been a recent development.

I am relieved that I am not the only person experiencing these symptoms!!
I will deffinately be contacting my psychiatrist ASAP

I had been taking Zoloft since 8th grade when I attempted suicide my junior year of high school (2003). I was then switched to Effexor, and immediately I went from an A and B student to a C student, then I got my first F my senior year, and then I failed completely out of college. My memory has gotten worse and worse, and I stopped taking Effexor when I found out I was pregnant in September of 06. My memory seems to have continued its decline…I have problems thinking of the words I want to use, I hugged my brother the other day then hugged him again because I forgot I had just hugged him. It’s inconvenient and embarrassing and has had a severe impact on my life in the most negative way possible. If anyone hears of a lawsuit against Effexor for this, please let me know!

I have permanent memory loss from this medication. I took it for approximately two years. When I went off of it, I was like an Alzheimer’s patient. Now I have memory problems that are fairly severe. If I didn’t know someone before I started taking the medication, I probably won’t remember them unless I see them on a regular basis (at least weekly). I just had ankle surgery and bus drivers will pick me up to take me places and remember me, but I don’t remember them unless they mention a specific event or conversation topic. It’s never gone away and I’ve been off the medication now for approximately 5 years. It’s not getting any better either. I credit this medication for destroying my brain. I wish there was a way that I could sue because this has done permanent damage. I have forgotten many of the tasks and knots I used to know on the boat (since I haven’t been doing them regularly). I hate my life now.

I have been reading so much about this drug that im taking and saying YES!!! that happens to me too!!! I have also read lots of message boards regarding the phenomenal side effects of trying to STOP taking Effexor, sounds scary. Why do doctors all treat us like we have no idea???

Oh, thank all of your people. I have been on Effexor XR for nine months and the memory loss started within a few weeks. Again, my therapist thought this was a sign of depression and stress but I have lived with depression and stress all my life and never had this problem before. I have had severe, migraine-like headaches and the buzzing in my head when I have forgotten to take a dose (not surprising!). Also, my ability to reason has gone way downhill. I used to be able to do a difficult crossword puzzle in a couple of hours and now I can’t complete it in a couple of weeks. Vision problems, too. Yikes! I’m getting off it now.

Ditto, ditto and ditto.

Concerned as my 28-year-old son is just starting Effexor XR as well. Guess I’ll try to intercede there!

Can someone elaborate on the ‘vision problems’ that several of you have mentioned?

I have been on effexor for five years and my memory has become increasinly worse. I can’t remember if I have washed my face in the mornings when I’m showering, whether I have put on deoderant (I have to smell my armpits to see if I have!). I’m a journalist and have an excellent vocabulary, yet can’t remember certain words I want to use in mid conversation, and cannot remember stories that I have worked on throughout the day. I definitely believe effexor is linked to memory loss and even though doctors say it isn’t, I think it is sometimes just better to trust out instincts. Effexor certainly helped me get out of bed, build a career and basically not kill myself, but after five years, I’ve decided that I’m going to get off it and see how I fare. Not looking forward to the symptoms of withdrawal but definitelty won’t miss the terrible nightmares (being raped, having AIDS, terrible things happening to my brothers, sisters, parents) and night sweats.

i was making a joke on the url question. hey !! i came to this site because i too have memory problems. i am 62 and when i decide to go to the other room from my living room to get a pen or something like that, i forget immediately why i went there. i have to go back to the living room and think for a minute to remember what it was i went to my bedroom for! We may have enough for class action law suit. But it would be hard to prove. effexor has done some good things for me and yet the “brain shivers”, and the memory loss is significant. i will say that i drink A LOT OF COFFEE. that may be one major factor too! who knows? Thanks!

I also will agree that since ive been taking effexor i have been having problems with my memory aswell….im finding it hard to remeber the easiest things…ill think about maybe gettin something to drink…get up and go to the kitchen while somewhat thinking of something else that was on my mind and suddenly i cant remeber what i went to the kitchen for and i take a minute till i remeber then i cant rmemeber what i was thinking about before i got to the kitchen….also i would like to add my hearing is alot worse also …when i listen to my walkman now i have it on full blast just to hear it comfortly.

I forgot to leave this little bit as i left….effexor has also effected my eye site aswell….blurred vision at times other times focus problems…seeing things move…..minor halusinations etc…i cant get off the effexor yet as it is helping me cope with my life issues but i would like to stress these symptoms im having are all in common with everything others are sayin about the drug. We need to let our doctors know because if they dont think memory loss eyesite are not effected they are just being ignorant it does indeffinetly…also the not so rare no sex drive which everyone knows about…im 28 and have zero sex drive now…been on effexor for only 6 months…..and i know i need to get off ..

Hi. Im 29 and I have been on Effexor for 5 months. I have suffered my whole life from anxiety and Effexor transformed my life since it worked from day 1 basically. Yet, about 3 months ago, I started noticing that I couldnt remember things, facts, vocabulary, movie titles, etc. I am the kind of person that always had a quick memory when it came to remembering facts (think … the gameshow Jeopardy). Now I have a tough time when I try to remember the name of a song, or an artist or vocabulary. This is the extent of my memory loss. I havent wanted to freak out, but the memory loss was immediate and noticeable about 2 months of taking Effexor and I cant isolate any other possible factor that influenced this problem. I have been getting off of it now, but I will admit, that I do fear that I will return to my serious anxiety and irritability problem!

I took effexor for 2 1/2 years, and had severe memory problems into the second year. Much memory recovered after discontinuation. My body couldn’t tolerate that drug any longer.

I did have permanent problems, but have found 250mg magnesium morning and night gives noticeable memory and thinking improvement. Phosphatidylserine complex with ginko helped too.

I am so relieved to have found this webpage. Effexor has greatly improved my anxiety like nothing else ever has but the memory loss and lack of concentration are not an acceptable trade off. I’m taking adderall to counterat this whenever I have a test – but that isn’t a long term solution. I can’t believe these side effects aren’t listed by the company that produces it. Nausea I could handle, but I need my mind.

Unbelievable!!! I found this site – thank God – after googling effexor memory. I NEVER had memory issues before Effexor XR. In addition, complete apathy is a newer symptom – not present before Effexor. I googled “effexor apathy” also, and I’m certainly not the first to go through hell because of Effexor. This drug has been around loooong enough for these bastards to know about the MANY negative aspects to this drug are. And all these SOB’s making antidepressants claim they aren’t sure how it works. Please. I understand proprietary information and all that, but I believe there is something more sinister. Thank you everyone for helping me understand that yes, I am losing my mind, but it’s because of Effexor!!!!!!!!!!!!!!!!

I’m glad that others are posting about their experiences with Effexor while being treated for anxiety related issues. I’m tired of hearing that it is depression that affected our memory and not Effexor when we weren’t being treated for depression. As I posted above, I was not a depressed person until I got off of Effexor and suffered terrible depression for the first year while the second year after abstinence from Effexor saw a decline in the depression.

Thanks to James for his post on June 19 regarding his use of magnesium and attributing it to helping get his memory back. My post from March 6 of 2007 focused on concentrated fish oils as having been a life saver for me and memory but I take lots of supplements including magnesium. I was actually taking the concentrated fish oil for the Omega 3 as I had read numerous articles about its effectiveness with treating depression (again, I was severely depressed AFTER I got off of Effexor) though most of the studies were how Omega 3 improves the effectiveness of depression medicines, specifically when individuals had a low tolerance level for such medications and were unable to benefit by such low doses but supplementation of Omega 3 helped compensate. Of course, the pharmaceuticals paid for these studies as there is no money in just proving Omega 3’s benefits. Other studies worth note are regarding those northern European countries that have short days to no days during winter while their primary diet consists of fish which of course is high in Omega 3. These same cultures have lower than average depression rates and most interestingly, extremely low SAD occurrences. I will now postulate that perhaps magnesium had as much to do with my memory improvement as the concentrated fish oils did and that the concentrated fish oils helped me with my depression. Brain food for thought!

Regarding Tracy’s post on May 10th and the vision question – I can only speculate that at least part of the problem has to do with Effexor causing pupil dilation or at least it did for me. I got a doctor’s note when I was on the stuff because it made my eye color look black (they are bluish-green) while being fair haired and skinned. I could be very freaky looking and had a few jokes thrown my way about being on cocaine because of the enlarged pupils and Effexor did make me terribly hyper. I noticed a decrease in the blurry vision very early on when I was weaning off of Effexor but again, I had only taken it for just over 2 years before quitting. If one reads up on presbyopia at Wikipedia:
http://en.wikipedia.org/wiki/Presbyopia
There is the comment that “Presbyopia, like other focus defects, becomes much less noticeable in bright sunlight. This is not the result of any mysterious ‘healing effect’ but just the consequence of the iris closing to a pinhole, so that depth of focus, regardless of actual ability to focus, is greatly enhanced”

Just my own speculation but I had very large pupils while on Effexor and very blurry vision. My pupils are now normal at all times and conditions and my vision has returned to normal as well. Additionally, a new Effexor overdose warning (Q4-2006) mentions pupil dilation as a symptom:
http://www.webmd.com/content/article/129/117271

I’ve been on Effexor now since 1997–I think that’s the earliest that anyone on this blog has reported. That’s 10 years now.

I am not a stupid person. But daily, hourly I act like I am. Daily I forget dozens of things. Sometimes at night I can’t even remember what I did during the day. What I had for breakfast.

I am not a stupid person. But my memory loss is getting worse and worse. And I can’t stop it even though I try everything I can possibly think of to be responsible.

So here I am, desperately looking for a reason that I appear to be getting Alzheimer’s at age 29.

Is it the Effexor?

What do I have but anecdotal evidence? I can say this:

At 29, there isn’t much chance that my mind is deteriorating from old age. But there has to be a cause for this memory loss–things don’t break down without cause.

My family has no history of memory loss. I don’t smoke, I don’t drink, I don’t do drugs.

I don’t do drugs–except Effexor.

From 150 mg a day for 6 years, to 1/4 of a 75mg pill for 4 years.

That’s all I know. Or at least all I can prove.

—

Guys (and gals), I sound very sensible to myself when I reread what I said–but the truth is that I am very scared that I will never be able to be a dependable person again. That I will always have this memory loss that makes me almost as reliable as a 5 year old.

Our evidence may be anecdotal, but when I understand personally what 66 out of 68 people are anecdotally saying about Effexor and memory loss–well, that’s enough to convince me to get off this drug.

And work desperately to try and recover what I can of my memory and brain function.

Good luck to all.

I found this site after googling “Effexor, memory loss” and I must say I’m relieved to see I’m not alone with this side effect. I find myself in the car driving down the street and have to think very very hard to remember where I’m going. Or I’ll go down to the basement to get something and find I can’t remember what I was after. That is scary. It also affects my work. I’m an archivist – and what is that about but memory. Yikes! I also have been experiencing profuse sweating. I thought it was hot flashes, but I’ve had those before and they are different from this. What I really hate though is the feeling of not really caring. I write plays and am having some success, but I have barely written a thing – and nothing new – since I started on 75 mg of Effexor about a year ago. I’m finally having readings of a play at important theatres, but I can’t work up the interest to keep writing. My creativity has just drained away. I think the sodium levels side-effect might be involved with all of this. Thanks for posting your comments everyone. I certainly appreciate it…and I hope to get off this drug soon. (But watch for those withdrawal side-effects.)

Well I have been on Effexor XR for about 4 months now and I am taking 150 mg daily or should I say nightly. This is after I told my Dr. that I was getting very sleepy at work, can’t have that, and the excessive yawning, so she suggested I take it in the evening.
The first 2 nights were hard but I wasn’t tired at work at all. The coffee helps!! After my last visit my Dr. said that after I have been on the Medication for 6 months then I will be SLoWly weened off. so I Don’t understand why anyone has been taking this med for so long. I do get tired during the day, but as long as I am busy, I don’t feel the need for a nap, once there is a lull, then I feel it.
Hope this helps someone. Pls check w/your Dr. it couldn’t hurt!
_M

PS
I almost forgot to say that if I don’t take at my regular time, I start to feel it, I get grumpy and moody. And yes I too have some loss of memory but that does come with age, so I write things down alot! Thanks for your patience!
-M

I can’t believe what I’m reading…this is me! I’ve been on Effexor in the past and never had the memory loss I am currently experiencing. Altho I’m also forgetting if I just took my vitamins or if I already fetched my book from the other room, but I’m also confusing words, substituting “like” words (lake when I meant park, Gloria Swanson when I meant Gloria Vanderbilt). Recently I had difficulty typing my login or password on the computer…the same one I’ve had for years. I was ready to go to a neurologist but now I think a trip back to the psychiatrist would have better results. Thank you all for sharing your experiences.

wow, I thought it was just me! When I came accross this I was actually relieved to know others have memory problems too with Effexor XR. I thought I was just loosing it! It would make sense that a mind altering drug could cause such a side effect. Doctors should be open to all things a patient experiences, since new things are found out all of the time.

I have something very interesting to add to yesterday’s comments. I found a site this morning while searching the web that looks promising. If you go to http://www.theroadback.org/weight-loss.htm it talks about anti-depressents and their side-effects. Effexor is listed and while reading through I saw, at another site they recommended to go to: Global DNA Solutions, something on what they called “brain fog”. I am going to try and eat the foods they recommend and avoid what they recommend to avoid. It’s worth a try, since I’ve already tried everything else! What they say seems to make a lot of sense to me and since Effexor has caused me to gain weight too I have a double reason to try it. My best to everyone.

I stop taking Effexor, 2 years ago, becouse of the memory loss side efect, hopeing that it will came back in time.Now I am afraid to say, but seems like slowly is getting worse. Can anybody tell me , if that is right, are we going to lose, whatever is left?

Correction on the road back web site:
The correct address is:www.theroadback.org/weight_loss.htm
Sorry about that guys.
PS – I’ve been following the program for 5 days now and I do feel better! Today is actually the first day I noticed it, but I definitly feel better.
Will follow up if it proves true.

I am so thankful that I am not crazy! Well, maybe I am, but at least I can attribute my severe memory loss to Effexor! I have been taking 75mg Effexor for my anxiety disorder for about 8 months now. I finally went to the doctor and asked to switch to another medication since my memory loss was starting to affect my job (I’m in the medical field, which should make everyone feel at ease!). Since I have been decreasing my dosage of Effexor, my memory loss has become even worse. From my research, I have found a connection between norepinephrine and memory. Effexor is a serotonin and norepinephrine reuptake inhibitor, so there is logically going to be an effect on memory. Unfortunately, I did not realize this until now. I encourage everyone to research this angle of the drug. I am NOT a physician, so I do not have all the answers. I just wanted to let everyone know of this connection. I empathize with all of you as I have also had such negative effects on my memory. I encourage everyone to not lose hope and not to worry that you are crazy. We will all make it through this!

I was prety desperate abut losig my memory, I have seen myself in a situation where I could not operate the TV remote (like someone said before). Never thought that the life can be affected so badly, I am a design engineer and the quality of my job was really affected. A month ago I start to take vitamin E and Ginkgo Biloba, for me works very good so far. Incredibly I gain most of my memory back.

i also have been on effexor for years,and sometimes i watch a movie,and have no recall what i watched,also i forget conversations i have with others.i have to struggle with what i did the day befor as i cant remember.its really quite embarressing,as i forget who people are,and how i know them.

I thought it was a long shot when I googled Wellbutrin and memory loss. And there this link was! I can’t believe it. I have done the craziest things. In the past three weeks I’ve taken other people’s grocery carts and can’t remember what I did yesterday! My question do you think this is permanent damage to your memory? If I go off the medicine will it come back? I think I’d rather be depressed then to lose my memory. That is very scary. I would hate to have alzteimers at age 44. Is the memory loss a symptom or permanent – damaging that part the of brain? I have heard that antidepressants do havic to your body but memory loss is to me one of the worst! Any thoughts? Thanks!

Darn, I wish I had found this page a year ago. I’ve been on Effexor for about 5 yrs. (Luvox 10 yrs. before that), to control the depression side of bipolar. As if the memory loss weren’t terrible enough, the multitude of “helpful” people telling me that it was stress, aging, my high expectations, etc. etc., has been enough to drive me to the depths of sorrow and frustration. But now that I’ve begun to decrease my dosage (from 300 mg. daily to 150 mg.), I have actually experienced the return of a functioning brain!!! And I am not experiencing a decline into serious depression. I can sympathize with every writer here; and I’m not ever going to let someone else tell me that I don’t know when something is wrong with my own brain. Would they do that if it were a broken leg?! I’m going to make sure my doctor and my family see these comments. If at my age (just turned 60), I can experience clarity of thought, return of organizational skills, reliable recall of general info., and a sense of well-being, then many others can expect to “get better” after Effexor also. I look forward to what I might experience when I’m at 75 mg. daily. With any imbalance of brain chemistry, or emotional stress, it’s real easy to not notice when the side-effects of medication are worse than the original complaint. This forum has made me determined not to lose sight of my goal, stick with it, and get back some semblance of ‘a life’. I’m going to check in often to see what else I can learn. Tks., C.

P.S. Just noticed that I didn’t clarify the time frame for decreasing the Effexor. I’ve had lots of experience with missing a dose and getting the dreadful electrical flashes. So I’m careful to avoid that. But it was due to complications getting my prescription renewed, and moving to another city, that lead me to take fewer pills each day. The change was noticeable within the first week! But I waited another two weeks to be sure. My system responded right away to the decrease in the drug! Believing I would require an anti-depressant for “the rest of my life”, I might have gone on like a zombie forever. Be sensible, but don’t be afraid to try it. If I eventually need a mood stabilizer, you can be sure it won’t be Effexor!

OMG I’m sooo glad to have found this site. I am the biggest idiot walking the earth on this stuff. I forget everything…My daughters girlfriends names, where they live, people I grew up with, whether or not I put deodorant on, did I brush my teeth?, every day things and work is a disaster!!! I spend lots of $ on continuing education and forget it all! The one BIG problem is it controls my severe panic and I don’t know what other drug to go on!!! My Dr. is patient and will let me try anything and I’ve tried them all with no success…Help someone!!!! Anyone ever use Paxil??? That is one I haven’t tried… Good luck to everyone reading this, hopefully we’ll all be “normal” one day.

Wow I thought that I was losing it! I used to be a really valuable employee because I had a great memory for procedure and was quick. Now I am having trouble following simple instructions (confusion). I used to be able to find the fastest and most economical means of doing things but now I’m lucky to get by without missing things that are “common-sense”. My memory goes to hell if I lose focus for a second and I have to work back from the beginning to remember what I was doing. I’m glad I found your comments I’m going to talk to my Dr. if I don’t remember to forget or forget to remember.

I have a 5 month old that I tried to stop taking Effexor XR for during my pregnancy. I was able to reduce my intake from 300mg a day to 75mg a day. I did not notice the withdrawal symptoms during the pregnancy that I noticed other times when I tried to wean myself off. I was so excited that I was so “well balanced” through my pregnancy, but about 6 weeks post-partum I became very unstable. I increased my dosage to 125mg, which worked for about 2 weeks, then quickly needed to double that. I have now been on 300mg for two months and my job is taking a nosedive. I may not be telling people my mind, but I also can’t seem to function. I type slower; I can hardly dial a phone number correctly the first time. I take my medicine and forget if I’ve taken it. I have conversations, and immediately forget what I just talked about. I have taken showers and forgotten to wash my hair, and even more serious consequences if caught, only to luck out so far. My doctors, more than 3 have said there is no connection. Even had an MRI. I too have had migraines, and they could see the anomaly in the scan, but nothing serious enough to cause concern. This medication has been the best thing for me over the past 3 years as it relates to managing my Bi-polar, but I’m thinking a change needs to take place if I intend to keep my job. Worst of all, I have no sexual drive that hurts the intimacy of my marriage. I feel trapped because overall I’m a better person on the drug, I just hate looking like an idiot, and I miss the closeness with my husband. HELP!!!!

Well…same here, as many of you. Been taking E for 10plus year…I am 41..my memory and concentration are terrible. My wife (sweet thing) is worried about me… I have tried to titrate off the drug, but second day can’t move my head without my brain staying still…Has anyone discovered a ‘cure’ for the memory loss? I am American, but live in another country…the language translation is killing me! The other side affects I can handle…the loss of short term memory, I can’t.

I have taken Effexor XR since May ( I think) and i have had severe memory issues. I stopped finally the end of September, and am still having issues with my memory. I’ll be glad when this medication is completely out of my system. A lot of doctors and pharmacists aren’t aware of a lot of the side effects from this drug. I think alot of the problem is doctor and pharmacist denial…meaning when someone comes in with these issues, they are blown off or given a different reason for their issue. I had a doctor try to suggest that my memory issues come with age…but i’m only 28. I had to explain to her, so she could understand, that I had no problems with memory and expressing myself before this drug and it’s not just some coincidence that right after i started this drug i had memory issues. This is not easy at all…because of these doctors dishonesty and misinformation i have decided to not take any drugs and learn to cope with my anxiety on my own with the help of a really good therapist.

Me too. I ‘ve been taking Effexor RX 75 for the last 4 years. I’ve developed memory loss I never had before. I forget my thoughts in the middle of a sentence. This is very embaressing especially when I’m at work and in meetings. Now I know I should get of this medicine.Thanks

I suffered SEVERE effects from this EVIL POISON.

People, I do not know which is worse – having taken Effexor XR or coming off of it.

I had extremely bizzare, TERRIFYING, frightening experiences as a result of taking this POISON, with devastating consequences. And yes, I suffered memory loss, too.

People feel BUZZING and ZAPPING in their heads!?

That is NOT okay!

It is NOT NORMAL!

IT IS NOT A “SIDE EFFECT”!

IT IS YOUR BODY LETTING YOU KNOW THAT SOMETHING IS TERRIBLY WRONG!

This is an extremely dangerous drug and we don’t need a “doctor” to say so in order to validate our claim. WE ARE NOT STUPID OR CRAZY. You don’t need to convince a doctor that the pill is bad, just ask them a safe way to stop taking it – COMING OFF OF IT IS AS DANGEROUS AS TAKING IT. Will a doctor tell you that? NOOOOO. Of course not. Will hundreds of people who have lived the experience tell you? YOU BET. Who will you believe?

Doctors think you don’t know what’s best for you, but that only THEY do.

No, they don’t!

They don’t take the shit, how the **** could they know???

And do you think a doctor will admit he or she has prescribed something so horrible and dangerous? Imagine how responsible they DON’T WANT TO FEEL.

Imagine all the money so many people WILL NOT MAKE from admitting this POISON can’t be manufactured and prescribed anymore (don’t worry, they’ll be out with the next horror show of a pill in no time).

You know what my problem is? I piss off a lot of people because I tell the truth. Then, they call me crazy and force me to take pills. Yeah, depression… bi-polar… panic and anxiety… who WOULDN’T be those things when you watch a news report of yet *another* shooting with the word ALERT flashing in red across the screen!!! How about walking past a news stand and seeing “SHOOTING. ONE DEAD” in bold black on white. How about hearing constant sirens! How about so many people walking around calling each other the most vile names? How about being treated like you’re less than human when all you wanted to do was make a payment arrangement with the electric company, which takes three calls (and you’re expected to be as happy as sunshine about that)… and you have to make a payment arrangement because WHO CAN AFFORD TO LIVE ANYMORE!!! Well, the manufacturers of the CRAP you put in your body are living just fine, I’m quite sure (Didn’t you see the pics of Aruba? Amsterdam was lovely…).

Oh, and don’t you dare express any anger to anyone about this… or you’ll be mis-labeled accordingly and end up prescribed!

You know, all I wanted was to

HEAL FROM ABUSE

Oh, stupid me, got that wrong… again.

I meant…

“recover from “depression”".

My memory loss is problematic enough for me to get off of Effexor. But that is not the only major side-effect I have experienced. After not taken the drug as liitle as 2 days causes what I call ‘brain zaps’. My psychiatrist basically laughed at me when I described this effect to her. But when I read about this side-effect on http://www.wikipedia.org I realized that others have complained of similar symptoms. I hope there will be no long term permanent effects as a result of this medication!

I have observed rapid onset of memory problems in my 86-year old friend after she started taking Effexor. The problem is once a person has cognitive problems it can be hard to recognize the precipitous loss of memory. I am trying to persuade her to at least consider the medication connection but it’s hard going.
Thanks to all who posted here.

ellen

I am 24 and have been taking Effexor XR for a few years. I think it saved my life because I had suicidal thoughts before. I have experienced memory problems, but I always thought it was due to taking Xanax. Does anyone know if the memory loss increases over time? I’m really young and don’t see myself going off medication because the withdrawal symptoms are so awful!

I was just looking around to try to figure out why I have sudden and frequent memory loss for about 6-8 months now. I have been on Effexor for a couple of years have tried to stop taking it or change to another anti-depressant several times but could not tolerate the side effect of tapering.
The first time I mentioned the feeling I can only describe as a brain shock when I missed a dose, the practitioner who prescribed it all but laughed at me. Understandable since I am, of course, mentally ill.
As each subsequent side effect appeared many of them, especially fatigue and confusion, where attributed to depression and my dose was increased until I was taking 375mg per day. I was still depressed so went to see a mental health professional. I did not know what was wrong with me but I knew I was not imagining it!
When I started to see the mental health practitioner last year, she slowly reduced the dose to what I am on now, 225mg. She would like me to go down below 200mg but anything lower and I am so nauseous, dizzy and of course what ever that thing is that happened when I move my head it goes on for days and days. I lasted 8 days on 187.5mg last time but could not stand it any more as I have kids to take care of and winter break was coming up. The ironic thing is that Effexor is not nearly as effective as other antidepressants I have taken in the past! Now the memory loss is getting so bad that I have started to get lost driving around town.
Like the other symptoms the memory loss gets more severe if I am even a hour late on a dose. Sometimes when I am active it starts in even less than 24 hours. I am certian that the Effexor is the cause as when I take it, some symptoms stop in a hour or so and most of them are diminished in a few hours. I can not remember the last time I went through a day without being dizzy or had at least one headache. I have had all sorts of test due to the symptoms and there does not appear to be anything physical to cause them. The symptom without physical cause do seem to confirm at I am at least a chronic complainer at worse that I am hysterical and manifesting physical symptoms due to depression.
I really do feel that this drug has destroyed my life. I am not being dramatic or fatalistic about this either I am on a medication that barely controls depression, it make me fell sick and dead inside but I can’t stop taking it because that makes me feel even sicker. Now, in the past week I have gotten lost driving home from a friends (less than 3/4 miles from my house), driving to Safeway (I got there almost everyday) and today I got lost taking my kids to Karate (we have gone three times a week for 4 years). I also feel that the manufacturer sort of has people taking antidepressants in a tight spot, because I am sure they and their high priced lawyers can make it seem that the symptoms are “all in our heads” and at this point I do not think there is anything I can do.
Today when I was reading up on the net, I am seeing other people who experience many of the same symptoms. Since this is the first I have heard of anyone but me saying these things I am 100% sure no one “planted” these symptoms and ideas into my crazy and so naturally highly susceptible mind. So I am glad to know that at least I am not alone.

Oh my, Effexor xr was the only anti that had an effect on me and kept me out of the black. On it for 12 years about and many of those years 350mg/day. My memory is pretty great but my vision seems to be heading downhill at an alarming rate and I need a lot of light to see. Can’t do sh__ after the sun goes down. Anyone else?

I’m 22 years old and have a been a suffering from social anxiety since end of middle school. Was on paxil for a while, stopped that, then took wellbuturan no success then started taking effexor. Effexor works amazingly for my anxiety. However it makes me sweat more and my memory is very messed up right now. I used to have such a great memory. However, I’m having the hardest time remembering things short-term and difficulty with my studies at school.

Constantly re-reading things because I forgot them.

Is there any solution? ANYTHING!! I’m so lost. I don’t know what to do. I’m currently on 125 mg a day dose. Was on 225 mg but i lowered myself due to feeling like a zombie. Plus i’m out of energy all the time and i could sleep all day if i wanted to.

I took this in 2004 for depression for 3-4 months. My doctor said that memory issues were not on the list of alternative symptoms that the medication causes. It took about a year for me to fully regain my short term memory. The memory issues hugely interrupted my life. It was my senior year of high school and I don’t remember prom, much of graduation or classes. It caused me to not go away to the colleges I had been accepted to etc. It was so bad that my parents and I had sticky notes all over the house of simple reminders for daily activities. It was embarrassing. My friends and family would laugh it off and try to work around it but it was frustrating for them and me. I would NEVER go back on that medication again.
Anyways, I saw an ad for Effexor on ABC Family tonight and I was very disgusted.

Katrina. A year you say. What medicine did you switch to if any? Because I know I would start to get bad anxiety If I was not on anything and would barely be able to come outside the house. I cannot let that happen. My doctors are glorified drug pushers that really don’t know much, except how my co-payment is. It so tough everything. Ugh. Well least I’m not alone.

While I’m so sorry you all have also been experiencing memory problems, I feel a great sense of relief. I’ve been having real trouble with my short-term and working memories. I experienced a brain compression injury ten years ago, and so I have been afraid in the last several years that my problems with recall (and finding the right word — or what is was I was in the middle of saying) were due to that and thus I was just stuck with it. And not being 40, I have been scared to death — my work as a project manager demands being able to keep scads of different and changing bits of info in my mind [ACK! I lost my train of thought for a minute just typing that last sentence!]

I have been on Efexor XL 75mg for the past 9 months and I found it worked very well for me. My doctor has advised me to wean off and now I am on 75mg every other day. It’s only since I began to cut my dose that I am having memory problems. This is especially true when I need instant recall, if someone asks me about a very specific thing that took place a few days ago – I can’t remember it. It’s a very spooky feeling – but I am not worried about it as I think it will fade away after I have stoped taking the meds. I never experienced this effect which I was taking the medication normally, its only since I drastically cut my dose. I am having very vivid & colourful dreams also – but I quite enjoy that part.

I was really releaved to find this list of postings when I did a search for ‘effexor and attention span’. I’ve only taken 37.5mg for one week and then 75mg for one week, but the effects on my memory and attention span are noticable, to the point that they were sacring me (and I’m not on the drug for depression, but to see if it helps a pain condition I have). I have a job that is really high pressure and I have to often be a public face and speak to groups. I was speaking on a topic I’ve spoken on hundreds of times and there were two basic facts (like names of Senators and what state they are from) that I simply blanked on, and then guessed wrong on, having to then laugh at myself with the group, because they were really really really basic things to my job that I know like the back of my hand. I also have found that in meetings I will suddenly discover that I haven’t been listening at all for the last few sentences, and I have no idea what the person is saying, in really important meetings where I am trying hard to catch every detail. I’ve never had that problem, when I want to be ‘on’ and great at catching every detail and responding accurately I’ve never had a problem before. I’m done and will never take another pill of effexor (or any other drug that messes with the mind). Scary stuff!!!

My god, this is so scary. I am 38, and I took Effexor for a few months 2.5 years ago……and now I am having memory loss. LIke the other people who posted, I have trouble recalling BASIC WORDS, like “squirrel”… I end up saying something like ‘BROWN RAT-LIKE THING” because I know the word (squirrel), but it just doesn’t come out. Now add to this that I am a scientist and work in a highly challenging, technical field, I am scared to death. I forget things in the middle of sentences. What I don’t understand is, why did the memory loss occur now, over a year after I stopped the meds? I am terrified that my memory may not return.Thanks to the people who suggested magnesium and fish oil to help. I will definitely try it.

i am so glad i found this website i have been on effexor xr for almost 8 years from 75mg’s and now taking 37.5 mg’s.i tried going off or cutting back my doses and i feel better but it effects my sexual functions by having and orgasm in less than a minute.i don’t not have a big sex drive either.i went to the doctor and explained what was going on and he said they use effexor for sexual disfunction so now if i want to have a better sex life i have to stay on.i am only 39 years old and my sexual health is more important to me especially being a man.but i also find memory loss in not even remembering what i did yesterday.

I have to say I am soooooo relieved to read these postings. I have always had the scary memory in the family, remembering details from years ago, even what people were wearing and exact words. Now, I can’t remember ANYTHING. I too have a high pressure job and the other day it took 10 minutes for me to come up with the word ‘orientation’. I had been on Prozac for almost 2.5 years for panic attackes when it stopped working (which the doc says happens often, but no one every told me) and my panic got so bad I had to do something, so he put me on Effexor. I started 6 months ago and am on a hi-dose (300 mg) after 3.5 months it stopped the panic attacks and if I have one now, it is so mild, I can really get through it easily. HOWEVER, my memory absolutely sucks. I am tired all the time and if I don’t get at least 8 hours of sleep each night I am literally sick. I also notice that if I take the nightly dose too late at night, I am really out of it all the next day (try to put cereal in my coffee and such) I honestly was starting to think that I had had a mini-stroke (I am 36 so that was worrying), but now I am pretty sure that it is the effexor.I can’t believe how completely HORRENDOUS my memory has become (can’t remember yesteday or things my husband told me) I also have the vivid dreams but DO NOT like them because they are so real that they seem like memories when I wake up or the next day if I think about them. I guess weaning off the medicine slowly is the only solution.I will have to go back to the doc and get a program going to do it.

I have been on Effexor XR for about 4 years. No memory loss, but if I miss a dose you will know in almost exactly 24hrs. I start to feel extremely tired, medicated, dizzy, irritable, spacy, and hard to keep my eyes focused and open. But once I take it, in about 2hrs all okay. Has anyone experienced this?
Now the comments about memory loss~ Are you guys taking any other prescription medications with the Effexor XR??

Now that I think about it, I have no attention span, its like my head feels tight and I just cant focus on single thing. It effects my home and work! My doctor put me on Adderall for my attention and it works great as ever.

Now that I think about it, I have no attention span, its like my head feels tight and I just cant focus on single thing. It effects my home and work! My doctor put me on Adderall for my attention and it works great as ever. Oh my gosh though~ I for sure get the head zaps, and its like my mind suddenly blacks out if I miss a 24hr dose.

Hi,
I have been on Effexor for 4 years and it controlled my anxiety very well, the side effects sweating and a huge memory loss. Anybody had asked the Pharmaceutical company if they know about this issue? To me it is very serious, and my relationship is effected badly, I am tired of being ashamed in front of my girl friend because I forget things.

I took Effexor for over 6 years, then on the advice of my new dr, started to wean off of it. I’d also been dealing with skin problems, and found out by accident that I may be allergic to the Effexor, because the skin started to improve as I decreased my dosage. As for memory problems, I haven’t had any. I wonder if that might not be part of the depression they are taking the Effexor for.

I googled “Effexor” and “memory” because I’ve been feeling that my memory is getting worse. It’s not listed as a possible side effect,and yet I read comments from so many people who are on Effexor. I had a series of job interviews recently, and I felt as though my mind was going blank trying to think of examples for the behavioral interviewing questions. I told them it was just because I was nervous, but I knew it was deeper. I had been a corporate recruiter for 10 years and have interviewed well over 3,000 people. So it’s not as though I didn’t know what to expect. I used to have strong verbal communication skills, too; but those have really gotten messed up, as well. I’m on 150mg Effexor (for 2+ years), plus Lexapro. At least I know it’s not just me.

As a footnote to my note above, I should mention that I was first diagnosed in 1980 (Bipolar Type II). I’ve been on two tricyclics, an MAOI, Prozac, lithium and Lexapro (which I’m still on, along with the Effexor). The Effexor was added a little over two years, after a complete breakdown.

I don’t recall having memory and verbal communication issues prior to the Effexor, but I can’t be sure. I know I definitely did not have them as a recruiter.

Every medication has some side effects. But I’d rather live with the side effects rather than die from the depression.

Thank you, thank you, thank you. I have been taking Effexor for 4 years. I’m on a low dose. However, I cannot finish sentences, and I cannot remember names, among other symptoms already expressed by others. When I shared these problems with my doctor, he felt that the symptoms weren’t severe enough to consider other options. I have been on many other types of medication for severe depression and social anxiety. Is there anything new on the market?

I am so glad I am not the only one!! I have been taking this drug for over a year and my memory really isnt working. Its really scary!

My memory is definitely worse. However, I am on 6mg/day of Klonopin which definitely affects memory. However, I do have a set of Effexor circumstances that has not been listed. When I was on my anti-anxiety meds and just Effexor for depression, I would try to read a page of the web or in a book and within 15min to 30min, all the blood sugar (or whatever) drained from my brain and I would become really tired and would not be able to think or read or anything and it would always last for 5 hours. Nothing I ate or did would cause the blood sugar or whatever it was to get back into my brain so my brain would function.

This same situation could be duplicated by walking fast for 1/2 to 1 hr and then all the blood sugar or whatever would drain from my brain leaving me exhausted and unable to think for 5 hours. Once again nothing I did would help the blood sugar get back into my brain, I just had to wait the 5 hours.

If anyone has heard of this problem, I would really like to learn more about it and try to solve it, especially since Effexor seems like it will play a part, though limited, in my meds therapy.

I wrote this up in another forum and the person that wrote the Wikipedia articles on the blood brain barrier wrote saying that it might play a part in the problem which he was familiar with.

I know that adding a comment won’t help anything, but I just want to put out there that I am suffering from serious memory loss after about 4-5 years of Effexor. I’ve been off it for almost a year now, but that has only made things worse. My memory in general seems to be intact, but I can no longer recall things well. Whether that be words, names, or things to do… I just can’t ‘call them up’ anymore. It’s affecting both my work and personal lives. I find myself avoiding conversation, embarrassed that I’ll make a fool of myself when I can’t recall something. I pray that there is something I can do about this…

Wow, i read this and i’m glad it’s not just me. I’ve been taking 150mg of Effexor XR for about a month now and I just have this disconnected feeling. It seems as though I am just not able to pay attention to anything and I try to think about things that just happened and it seems like it happened forever ago. I especially have trouble driving b/c i feel like i just can’t focus. The doctor says these side effects will go away, but i doubt it from reading these postings. I just can’t function like this. What should I do?

I took Effexor for a couple of years and then my doctor took me off of it because my blood pressure skyrocketed. I have been off of it for a while now. I don’t remember the memory loss issue, but the bp was really scary. At one point my bp was so high that the dr. wouldn’t let me leave the office until I took something to get it to normal. After that I took bp medicine. When I went off the Effexor, the bp issue resolved itself. I took 3 different meds for a long time–Wellbutrin, Zoloft, and Zyprexa. I am now off all but the Wellbutrin. I have had days of recurring depression–the fogginess and feeling of being in a deep hole with no real way out, but it passes and I can be back to normal. Now that I am through menopause, I am hoping I can go off the antidepressants, but I don’t want to fool myself. And I don’t want to get into a deep clinical depression again

I’ve been on Effexor for a few months, can’t remember how long…but have found that I can’t get my thoughts together when speaking to others, trying to form the simplest thoughts is a daunting task at times. I can see in my mind’s eye the words I want to use,but can’t get them out. I also feel a little lazy…I look around the house and see things that need to be done and then think “nah” can’t be bothered…and that’s not me, and I feel I’ve gained weight, which I definately do NOT need to do. On the other hand, it’s helped greatly with the anxiety. I’ve tried others…was on Prozac for years, but it caused me to cough continually…only didn’t know that til last year. I don’t what’s next

I have been on Effexor XR for over 5 years but unsure when it started. I experience an internal tremor(TD?) on a consistent basis, vomitting, uneasy stomach, night sweats, irregular sleep patterns, irratibility and my memory seems to have gone out the window. I thought this was due to a major life event; however, a break down occurred after my perscription was cut in half on error and unnoticed several. I’m highly concerned due to various descriptions of, irreversible side effects!

I have been taking Effexor XR 250 MG and have no short term memory anymore. I have been getting used to writing everything down because the meds have been a life saver otherwise for my depression. Nothing could shake it before – no other meds, exercise (I just ran the LA Marathon), traveling, keeping myself busy. I am glad to be reading this because being only 34 years old – I knew it wasn’t old age. Thanks everyone for the comments.

I’ve taken Effexor XR for years, I honestly can’t remember how many, in both the 75 and 150 mg. doses. I have to say that also having taken several other depression/anxiety meds that Effexor has worked the best. I’ve done things I was never able to do and so on.

However, I have wondered for a couple of years now about some of the side effects – memory loss, concentration problems, sleep issues, weight gain, blurred vision, severe apathy, mini hallucinations, ridiculous sweating – and have had them brushed off by more than one doctor. Until the memory loss and concentration trouble along with some serious apathy issues started, I was fine with dealing with the side effects, it was worth it. But after having job problems due to being perpetually late and unorganized and forgetting things I tried discussing it with my doc to no avail. Told me to stop smoking…*eye roll*

So, I am calling tomorrow and telling, not asking him to wean me off the stuff. The zaps and brain killing headaches are about to commence, but
I can’t deal with what’s happening to me any longer.

at first, there were supposedly no adverse effects from stopping the medication, I know several people whose docs cold turkeyed them off of Effexor and they suffered some horrible reactions. Then years later, ta-da, Oooops, we were wrong…

I wonder what’s coming next?

I am shocked to see so many postings here! I have been taking Effexor XR 225-300mg/day for 10 years now, and the memory problems started to worry me about two years ago. I have always been extremely organized, and have had a good memory. What I noticed initially was that I seemed to be so scattered/unfocused mentally and disorganized in my job and personal life. I thought that I just need to get back into exercising (after an 8 month hiatus), as that has always provided such a boost in my overall quality of life. I also had my thyroid hormone levels checked to make sure my synthroid dose was doing its job. My endochronologist increased my synthroid slightly and I continued exercising, but here I sit today, and I find myself constantly mispelling very common words, consistantly forgetting where I parked my car, recalling very little of important meetings at work, as well as what I read for work and pleasure, forgetting where I’m going, why I’m going there in the first place, etc. I am only 34 years old and I can’t even imagine what I will be like if this continues to escalate over the next ten years. I have had MRIs and cat scans due to other weird neurological events (1. chronic headaches and fainting at age 8, 2. an episode of severe numbness in my face about 6 years ago, and 3. an episode of extremely sharp head pain that woke me out of a deep sleep, followed by dizziness). In each case, the docs found nothing abnormal, except for incident #3, where they found a pineal cyst, which is supposedly common and nothing to worry about. I can say two very positive things about Effexor, which is why I have been so hesitant to go off of the drug: 1. It dramatically helped my depression. I suffered since I was a child from severe, suicidal thought, and half-hearted attempts. 2. My chronic headaches greatly diminished. I suffered from chronic headaches, sometimes daily, since I was a child, and since I have been taking Effexor I rarely get them, except for the scary one I described in “weird neurological incident #3. It would be nice for an epidemiological study to be organized around this experience of memory problems associated with Effexor. I don’t know how scientists/doctors decide to embark on a study such as this, of a drug that has been on the market a while.

Well, heck. I don’t know if I’m relieved or alarmed to have found this site. I have been getting increasingly alarmed at the vast amount of things I’ve been forgetting. Things that others have noted – spelling simple words, going into another room and totally forgetting what I was there for, sitting in front of my computer in the middle of a project and absolutely not remembering what I just did, etc etc. I have even had difficulty simply saying words at times. I was flying back from a business trip last week. The flight attendant asked if I wanted anything to drink. I could not remember how to say ‘tomato juice.’ This freaked me out. I am a writer and public performer – the thought of my brain continuing to be full of holes really alarms me; the thought that it might continue to get worse terrifies the hell out of me.
I have one theory about why this might be happening. I was prescribed Effexor for depression as well as anxiety. My anxiety would manifest itself in not being able to let go of thoughts, ceaseless worry, my mind playing scenarios past and hypothetical over and over again. I was relieved to see much of that go away when I began Effexor 5 years ago. But. I think the same chemical mechanism that encourages the neural pathways to let go of worry is not discriminating. I think the mechanism cuts far too wide a swath so that not only are anxious thoughts and worry dispensed with, so are every day memory tasks.
I appreciated what Effexor did for me at first. I did lift me out of a very dark depression. But trying to get off of it has been very difficult. I’ve had ‘brain shivers’ which I’ve seen described here and on various other Effexor side-effect sites: the sensation of an electrical current running through my brain and my skull. It is painful, jarring and very disorienting. With the help of a psychiatrist I have gone from 150 daily dose down to 37 – after I normalize out a little more on this 37 mg dose I’m going to do away with it altogether. And I hope and pray that my memory function comes back. I can not live like a doddering old fool.
I am wondering if a class-action suit may be under way for this. Certainly our experiences are not the only ones. Surely the sameness of our experiences tells us something. I read here that lots of doctors and pharmacists are saying, ‘Impossible. That can’t be a side effect.’ Bull crap. After we’ve seen how many pharmaceutical companies have deliberately hidden information they knew about side effects of medications like … (see, here’s a case in point. I can’t remember the name of the prescription drug that was prescribed for high blood pressure that caused dozens of deaths. . . I can Google it, of course, but my brain should remember it. Damn it!) I no longer trust pharmaceutical companies. They will do anything to turn a profit, even cause hundreds of deaths or permanent disability in order to do so.
Please — let’s keep this line open and do what we can to help one another with information, and how to regain what we have lost.
Eric in Seattle

i have been on effexor xr now ofr over a year….i thought i was loosing my mine…i kept forgeting everything…. i would lose my keys are forget something my kids told me and i would ask them again and it would piss them off……because i have to ask them several time….help!!!!!!!!!

I have been experiencing the same problems as well with regards to vocabulary degradation. It’s almost as though the vocabulary that I’ve spent so many years seeking to build was wiped clean when I sought to stop taking this medication (Effexor XR). I mean I felt as though I was going to lose my mind as my ability to clearly express myself was one of my most treasured characteristics. I fumbled to find words to convey what I wanted to say as well. It nearly killed me! After about two (2) weeks, I regained my ability to express myself. Seeing that I’m a poet and lyricists you cannot begin to imagine how devastating this experience was for me.

I was placed on this demon (Effexor XR) for a severe anxiety disorder. However, I think that I’d prefer to suffer from the most ruthless of anxiety disorders than to not be able to express myself.

I am seeking out this plant called “St. Johns Wort” which I’ve been told sooths and relaxes the nervous system as well, but without the dreadful side-effects.

I’m sorry that those of you who have experienced the hand of this monster have so been dealt, but I’m happy to know that I’m not alone.

I began taking Effexor XR, 10/2007 and discontinued (Dr.’s approval) 03/2008. Since then I’ve been fine; however, my productivity at work declined drastically! I was written up for below average productivity and for an entire month of data entry, I don’t recall any of it! My boss brought it to my attention that I did a lot of things wrong and I don’t know where and how I could have possibly gone wrong. Even little things that I’m normally great at, have become a challenge, like spelling words, and remembering to return phone calls. I began taking the meds to deal w/a bad relationship-in which I give credit to Effexor b/c I’m no longer in that unhealthy situation but, my memory has been affected. I’m extremely cold to the subject of my ex (now) but, the memory loss and low attention spand is not good. I’m calling my Doctor tomorrow. I don’t want to loose my job b/c of the “after” effects of Effexor.

I am soooo relieved to find out I am not the only one having memory issues. I am not dealing with depression anymore, but still have a “normal” amount of stress in my life, but am learning more helathy ways to cope. Anyway, started the effexor XR 75 mg in sept 2007 and still on it now and my memory is like badddd. i can go get something to eat, then an hour later wonder what and if i ate and with my kids i will ask them the same questions and have no clue i ever did and names are history! it has been scarry for me because my Dad was diagnosed a year ago at age 85 with dmeentia and it has really progressed. What I am wondering, is the memory loss permanent? I can not find out much about that. honestly, on such a low dose, i want to stop it in sept and now i am very concerned if my memory will come back! thanks for any input.

Wow,I’m a little relieved at the amount of comments in regards to the memory loss and effexor. My family has a history of anxiety and depression, and I was put on Effexor 2 years ago. I’ll be honest, sometimes I feel like I have no short term memory. Before I looked up “Memory loss and effexor” I actuually thought about writing down all the times I have mis-placed things at work, or the other times I have just been confused. I will say this, I am in no way going to stop the Effexor, I dont feel like I have ever been happier about my life, but this memory thing is really starting to bug me!

I have been on Effexor for approx. 7 years and have noticed significant memory loss. These include both long- and short-term memories. I recently had an incident where I could not find a friend’s house since I could not recall where her street was located and I drove back and forth along the main road with no recollection about any of the landmarks that would help me find her street. This was very scary indeed. Yesterday, my husband commented about the firework display we saw in Wash. D.C. in 1983 and I have no recollection of that either. I find I have to write everything down. Sometimes at work I think I didn’t complete something and then I find that I had already completed it. So I have become very inefficient, often duplicating my work only to find later that I had already done the same task. Very frustrating!!! and time consuming!!

I have been on Effexor – XR 75mg for just over 6mths. I have been very concerned with inability to grasp information and retain it, I knew the cause of my memory loss and concentration was related to Effexor -XR and I have spoken with my DR and asked to come of it.

I have been using the method of loci to remember things since my in-ability to photograph pages and information, I have been concerned and very frustrated with having to learn new ways of remembering things and holding information.

I now have a 300 point journey (memory palace) around my house for all my weekly tasks using “method of loci”. It is satisfying yet concerning that others have experienced the same thing as myself with memory loss, I’d like to know if I will ever get my ability to capture information like I use to 6mths back.

I am in the process of getting off this med. I feel that it has effected my ability to think. As my Dose is lowered I feel that I can think better and feel happier???

I have been on Effexor for 6 months. 3 months at 75mg and then went down to 37.5 overnight. No side effects. The main reason why I wanted to lower my dosage was the loss of memory. I could barely function. 2 weeks ago I decided to get off Effexor. I have been reducing my dosage by using a technique called ‘beading”. I open the caps, count 1/4 of the beads and thats working great for me. The only side effect is that I feel a bit fuzzy and my memory is getting worst but i know it will get back to normal as soon as i am off this awful medication. So far, so good. Im glad to see Im not the only one that noticed the memory loss side effects. If I would have known, I would have never started the meds but Thank God, getting off is not as hard as it seems.

I have been on this medication for about one and a half years (75mg). Have been reading some of the other posts and, not surprisingly, my memory has gone to pot since I’ve been on this hellish drug. I tried to get off it and starting by skipping 2 capsules in one week but became tearful. Any advice about the best way to get off of Effexor XR?

Hey, I’m too am on Effexor for about 1 yr and I think it is just the medicine acting like Xanax which calms you and helps keep you calm. This medication is an antidepressant and an antianxiety med. It keeps you calm and feels like you are losing your memory, yet I find since it also makes you tired and makes your muscles feel weak that if I take some energy pills then it helps me stay focused while still working to keep me from getting depressed and having anxiety problems.

I’m 19 and I was on effexor for awhile. It made me feel like I wasnt real, or I didnt belong anywhere. It’s so weird. I got off of it as soon as I started feeling like that and I still do. I will probably feel like that the rest of my life. I have the memory problems too. I’ve heard that your brain has a defense mechanism that protects you from really remembering parts of your past by making it fuzzy. I dont know how true this is, but I think this med has alot to do with the memory problems too.

I just stumbled across this blog. I think I just had a panic attack while reading these comments. I first came down with severe depression in March 2001. I committed myself to 4 (FOUR) short term psychiatric facilities. I had been on Celexa, Paxil, Klonapin, Xanax….for 6 months with no level of any of these alleviating my depression. In mid August I could not take anymore. I attempted to sever my life from this earth. My attempt landed me in my state psychiatric hospital. I responded to Lithium and then I began taking Effexor XL. I was released 7.5 months later. Since March of 2002, my memory is no more. You’ve heard of a ‘photographic’ memory? I HAD one. My days in school and college were easy. I could shut my eyes and see every page of notes I had taken. I even began taking college notes in colored inks. This allowed me to recall my notes/pictures, ideas even easier. I could recount conversations from work, which I needed very much to do to keep my job. Now I walk out of my house w/out my car keys, my wallet, my lunch for the day. I forget my bills, my glasses, which errands I need to run. I can leave my house to run to the store and return four hours later, having gone and visited everybody else, but didn’t remember to make it to the store I needed to visit. I get the same crap answers from my doc, my shrink, my counselor. Nobody wants to hear it. I no longer look forward to earning my Masters, changing jobs, or even excelling in my current job. I can’t remember anything. So I write it down. And of course, I forget to write some of those things down. What must be done to prove some of these psyche meds do have an impact on memory? We need to have specific studies done. I can guarantee the drug companies won’t dare to do any studies showing their own medication can clear your memory. One point of distinction. This seems to only affect my short term memory.

To follow up on my previous blog, I have taken Effexor XL since December 2001. My memory sucks and keeps worsening. I, too, find if I forget to take my Effexor for 2-4 days, I hit a bout of depression again. I was in denial that it could have been me missing a few days worth of doses. I finally got the nerve to ask my psyche doc. He said, of course !!! My laxity in missing a few days was the cause of these bouts. Effexor has a half-life of several hours. While it may take weeks to get the drug to have a clinical response to it, it only takes a few days (depending on your dosage) to clear your system. Then you become depressed again. So, do not miss your dose. Write it on your head if you need to!

Hi sawtoothbackpacker

We have exactly the same problem, did you read my comments above at all? I too had the same memory type as you and today was my last day in taking my EFEXOR XL, I reduced my dosage to 35mg, I feel relieved and I’m drinking lots of herbal teas to assist with memory recall and Brarme too. What happens when you look at something and close your eyes – can you mentally recell the image faintly or has the photo memory been suppressed? It’s the way our brains are hard wired I think the drug has only suppressed our ability – well at least I hope so! I have had to write things down instead of picturing every word in my mind – this new way of remembering things and learning has been awful!

I forgot to mention what herbal Tea I have been using:

Ingredients: panax ginseng
siberian ginseng, gotu
kola, licorice root, &
hibiscus flower.

Enhances energy, adrenal
stimulant, improves mental
function & memory.

Brahmi (Bacopa) carries properties that improve mental functions by a modulation of the cholinergic and GABAergic neurotransmission. Brahmi works scientifically as it restores the frontal cortical muscarinic and cholinergic receptor activities and hence it will improve the mental quotient, memory span, concentration ability and stress threshold.

And Brahmi…

Brahmi (Bacopa) will also help reducing the level of tribulin, an endogenous Mono Amine Oxidase inhibitor, which is elevated in certain degrees of anxiety. Brahmi will also ameliorate some of the attention fluctuations and other behavioral problems. It possesses exhibiting anti-parkinsonian activity significantly by enhancing the dopamine post-synaptic receptor activity. In proper dosage, Brahmi also works as safe and natural sedative and tranquilizing agent and hence it offers protection against convulsions and is also beneficial in insomnia.

I have the same memory problems – but from Aropax. I stopped taking that in 2002 and the memory is better but no way near as good as it once was. Now Aropax is an SSRI (seratonin) and Effexor is an SNRI (seratonin + norepinephrine). If both drugs cause this memory loss, then it must be the seratonin.

What I’d like to find is a drug that just does norepinephrine, since that seems to be for anxiety, which is just what I want and reduces the possibility of peripheral damage.

Why do we track down the website for users of *that* drug and see if (a) it works and (b) causes no memory loss?

this is said I seen it happen to my mother in law and they said it was dementia. That said its still on the market!!!!

I can’t believe I didn’t search for effexor and memory lost before now. I started taking it 10 years ago…and my short term memory is terrible. I do feel stupid and I don’t like it.
It started not long after I had been on it
and I did consider it to be the effexor but I’m
pretty sure my doctor told me it wasn’t likely.
I’m worried about the withdrawals though.

I was on Effexor XR for 3mo and stopped it immediately against my doctors wish. She told me to “stick with it, it will get better,” my memory was so bad I would run through red lights, I didn’t remember driving home from work, I lost 12lbs and she blamed this all on the depression, I never had this problem before and after I stopped taking it, it took several months to get my memory back, and I swear it’s still not as good as it use to be. I TOTALLY blame it on Effexor!

I am so releived that it’s not just me who is experiencing these symptoms. I am 28, have been on effexor for only 2 months now for panic attacks… and suddenly coworkers are having to remind me of things that were discussed last week, last month, etc, that I have no recollection of. At first I thought they were joking but it turns out I really am losing my memory. I’m glad I discovered this is a side effect NOW, before continuing on this drug for years and years. I am going to get off of this immediately. If I have to choose between the occasional panic attack, or feeling like an idiot/being forgetful in the workplace, then I choose the attacks… and it’s not just losing my memory at work. I’m a college graduate, I qualify for Mensa, and still I forgot how to spell the word “are” this morning and had to google it. So sad.

I missed taking Effexor one day and spent the entire day in tears and in bed.I was a wreck.I didn’t realize I had missed it until the next day when I discovered my dosage in the bathroom.One missed day caused all those emotions!I am afraid to stop but just as afraid to continue after reading what everyone has had to say.I could have written any of those because memory loss ,High BP and fatigue are always there now.I stumbled upon this site and I am glad I did.I hope I can REMEMBER to return…..

Thank goodness for all of you who have made a comment here. I started taking Efexor about 3 months ago (my Psychiatrist took me off Lovan as it didn’t seem to be working anymore after 5yrs of taking it) and in the past month or so I have been having extremely frustrating memory loss. I thought at first that maybe it was due to feeling a little tired and that getting to bed earlier would fix it. But that of course, didn’t make the whole memory loss get any better, in fact, it has become a lot worse. My partner and I will have had a conversation about something the day before and I cannot remember it. Last weekend we went out for dinner and the following day I couldn’t remember where it was that we went! It is so embarrassing, as people must think I’m such a ditz! And I’m just not like that. I am normally a very organized, methodical person. I’m at a loss as to what to do from here, because last time I came off my meds (the Lovan) I had to be admitted to a Psychiatric Hospital so my doc could monitor me while I was changing over to Efexor. And I’ve heard that coming off Efexor isn’t the nicest of meds to do so. And to be honest, as far as Efexor being of any help for my depression and anxiety (including OCD), well, it just doesn’t seem to be all that worth it!

I’ve been trying to ignore the memory problems but yesterday I left my car running, unlocked in a parking lot for 3 hours. Imagine my surprise when I returned! I could have lost a brand new VW Eos because of this drug, not to mention the more important thing..the effect it has on my brain

The same has happened to me. It has also made me feel quite apathetic; I don’t care about anything (myself included). My doctor said it was a symptom of depression. I know it isn’t! My memory used to be perfect. I’m only 20!

On Effexor for 17 years (plus Prozac). I recently had to take voluntary layoff because I could not keep up with the production required as a medical transcriptionist. I fear not being able to do transcription ever again, my memory is so bad, I have to double check everything I type. At 58, I read that old age is not a reason for memory decline. I have no job, I have little recall ability and I am my ownly financial supporter. Not sure if Effexor or combination Effexor/Prozac could cause this, but feel I have been robbed. How can I get another job ?!@

Yes, I used effexor for only a month… I couldn’t tolerate it b/c I was very forgetful and spacey. I would forget important things at work. When I told the doctor, she made me feel like I was crazy.

Effexor and Lexapro made my memory horrible. I am no longer on either medication and my memory works a lot better…I’m not at 100% but real close. I have been off Effexor XR since September of 2007.

Hi, I’m Francesco from Italy. My english is not good.
In fact, I notices little memory problems with many antidepressant I’ve been treated on, and efexor is only one among them. With anafranil (clomipramina) I lost the sense of what I was saying just before.
The things that I remember with more difficult:
1. things I eated in the last days;
2. association face-name of people;
3. If I’ve taken the medecine (efexor now)
4. I have some little problem in remembering things I’ve read, even if at the moment it seemed to be fixed in my mind.
Paradoxically:
1. Still remembering , like an elephant, many facts of the remote past of my life, even with no importance
2. I notice, but I’m not sure, that I remember now better that in the past songs and things I’ve heard.

I’m worry if there is evolution of these problems!!!

I am having all of the same side effects and my doctore refuses to take me off. I am getting in trouble at work for making stupid mistakes. I waste so much time a day looking for things I just had in my hands. I have gained a ton of weight no matter what I eat. I have gotton soooo lazy and tired. I was told by the doctor to excersize and that will help with energy, well it doesn’t. I just want to take a nap after. It does wonders for anxiety but it is causing more anxiety for the fear of the consequenses the side effects are getting me into.

Is this drug really legal? Does the company know what it is doing to people? Why do doctors keep pushing it with all these aful side effects?

I am Screwed, I have been in effexor for 8 years, and all of the above. I have neurological disorders and take other drugs, Lamictal, Modafinal, Aanax. I was sent to a loony bin once. well i walked into hospital a bit manic and wanted to talk to someone. They drugged me, stole my person items, mobile phone etc. Did not complete the admittance formes regarding my medical usage. I specifically stated i was on effexor!.

I was drugged with 30 mg of zyprexa per day. My effexor was abruptly ceased. I was also taken of my dexamphetamine abruptly. Add to this 1500mg od sodium valporate and 2500mg lithium.

I was a zombie.

I told them i had a head injury, and i proved it. They are yet to be held accountable, for my current state or lack of if u know what i mean…..

Forever to be lost……… CDB

I am glad I am not alone, I too have had memory loss, my doctor has taken me off for that reason, but the side effects are much worse than the memory loss, what are we going to do people, we are in a catch 22, who is going to pay for this???

I thought i am having an early sign of dementia! i;m only 38…i am having a hard time remembering …specially i just started a new job….It’s been hill for me now for almost a year.

I am so happy to find 150+ comments about this! I have been taking Effexor XR for 1.5 years. Most of the first year was at 75mg because I was pregnant and they wouldn’t give me more, then I went to 150 and then to 225mg. I started Effexor right before I got pregnant. People said my memory loss was common with pregnancy and not to worry. However, I had the baby and my memory was still horrible. Mid conversation I would be unable to remember a word or would lose my train of thought altogether. My husband was getting sick of hearing me say “sorry, I forgot”. I finally linked it to Effexor because it seemed to get worse as my dosage went up, but my doctor just smiled and said it wasn’t because of the meds it was because I had a one year old at home and was focussing on her instead of other things.

I am a chemist, I have always had a really sharp memory. I was really insulted when my doctor just blew me off. Now I’m really happy that I found this site. I’m not the only one. I was getting brain zaps too, but never mentioned them to the doctor because I didn’t even know how to describe them.

I asked him to switch my meds because I wasn’t happy with all the side effects. So, now I’m weaning off of Effexor XR 225 and starting to take Cymbalta. I know that will have side effects, too, (libido be damned), but I just want my mind back!!! I want to have a conversation without someone having to finish a sentence for me because I can’t grab the right word!

Thanks everyone for affirming that I’m not really losing my mind! (an my doctor should try surfing the web sometime)

I didn’t notice an significant loss of memory while on the drug. I was only on it for about a year and took a very low dose at the time. I did, however, notice that after weening from the drug I still have these weird electrical sensations that shoot through my body when a loud dull noise occurs….especially if my body is in a relaxed state when the noise happens. This is the same thing that had occurred during the weening process, not entirly painful, but discomforting none the less. Good Luck…

Ineffexor
No result at all after 9 months of effexor prescription.I am still very depressed and unable to face the realities of everyday life.(treatment from 2×37.5 to 3×75mg now).Before my depression I was always enthusiastic and positive(teacher).My psychiatrist keeps saying that it is because of the depression ,and not the inefficiency of effexor.Personally I Think the treatment doesn’t help me at all .Thank you for your experience and opinion on this topic.

I took was on Effexor and weaned myself off after taking the medication for two years. I began experiencing memory loss and lapses about 6months into the two years. This affected mt family life, social life and job which I was released from, they did not know I was taking this medication. While I am relieved that I am not the only one, it doesnt change the ‘alone’ feeling that I do still carry with me. I wish I would have thought to have an MRI done pre and post medication, maybe it would have shown?

I googled “memory loss on effexor xl” on the off chance that it might provide an explanation as to why I have gone from having a photographic memory in college to someone who feared they might be getting early alzheimers at 34. I’ve been on Effexor XL for about 5 years now, for the majority of that time at 225mg. It has had a wonderful effect on my depression and social phobia, but in the past year my memory has turned to mush. I’ve become more worried recently though with people telling me I’ve already told them something just a few minutes earlier and not being able to find words I’m looking for. I was never the best at remembering people’s names, but when you struggle to remember a colleague of nine years name something must be wrong. I’m due to see my psychiatrist next tuesday, I will be printing out the comments of other’s on this site and asking that he takes me off effexor as soon as possible.

Same thing with me! I am 56 and been on Effexor a couple years. I can’t remember anything. I feel stupid and forgetful. I also have no attention span. I can’t sit for even a half hour. I also don’t sleep well. At this age and with depression….if it’s not one thing, it’s ten others. Good luck to all.

I am so glad I found this site. I thought I was the only one. Memory loss is driving me crazy!! Can’t remember people’s names, words to songs, etc. I have missed more appointments than I’d like to admit to. Sometimes I feel like I’m going crazy. I am glad to hear it’s not just me. PLEASE tell me that my brain isn’t screwy and than I WILL get my memory back?! Also, how can I get off this stuff? I am only taking 75mg daily. Thanks.

WOW… and I thought I’m getting old and loose my mind here. I’m only 44 years old and need my brain for a couple more years here. Basically I experience all of those same symptoms as described by many of you here. I start a sentence and can not finish… pause for words… forget things and can not live without my PDA anymore. It’s very scary… and make you feel stupid. Also… ever since I have been on Effexor my eyesight went within a couple of weeks.
Last year I went through a divorce and also switched meds… BAD timing!!! … so after the doc tried me on the 3rd drug within 6 month, I crashed… BAD (suicide attempt etc.)
Since I did not respond to any med I was convinced that ECT (E-shock therapy) was my last resort.
I also started on a combo of Effexor and Wellbutrin… but blamed the ECT for all my memory problems. (you loosed some through the treatment… but are supposed to recover your memory)
After over a year now and reading this blog… I’m CONVINCED that the Effexor is screwing me up. I’m a computer specialist and NEED my brain to earn a living… I HAVE to stop Effexor… and fast!
Thanks again for all of you that have posted here…

Its become a standing joke at work that I am forgetful – I forget my swipe card to access work more than once a week, lose my keys and the other day left my phone on a table. Last year I got a certificate on a ski trip “forgetful skiier of the week” for doing silly forgetful things. Joking aside, its since I have been taking effexor – I’m ready to come off effexor now and I hope that I get my memory back.

I’ve been on Effexor XR for the past 6 years. I don’t have much of a memory, so I write things down. My attention spand is as if I had AAD. However it seems to effect my short term memory more than it does my long term memory. I can still remember things that happened and things that were said when I was a kid, but I can’t remember to pick up lunch meat that the grocery.

The problem with stopping Effexor, is that you start having those horrible mood swings again. I tried it, and I get suscidial, and just go pain nuts.

I’m another. I’ve always had a fantastic memory but just lately things aren’t coming into my mind when I call them. I’ve put it down to having babies (for those of you who have them you know that one) and age or 20 years of social drinking. Someone only just said to me that her brother had lost his memory from anti depressants he was on (more than me)and so I too Googled Effexor memory loss and here you all are. My losses aren’t as bad as some of you. I have been on about a year on 150mg but I do experience some unpleasant feelings if I don’t take it at exactly the same time of the day but all other potential side effects don’t seem to affect me anymore. I would say to anyone who wants to come off it, do it how your Doctor advises or you probably are asking for a hard time. There’s a reason why your Doctor tells you to do it the right way because they don’t want you to experience a setback. I know this because my brother went through a cycle of suddenly starting and stopping meds with the obvious consequences. Anyway, thanks for all your comments. I hope we all get to a point very soon where we can come off this drug and enjoy our lives without it HOWEVER it has most certainly helped me to enjoy my life a hell of a lot more in 1 year than I had in the previous 5 without it so I’m not rushing it. Take care.

I have been on Effexor for my chronic headaches. I was on topamax before (another memory loss med.) Before meds, I had a great photographic memory and was more in-tune to my feelings, the world, nature, and what was around me. I had great judgement and was a whole lot better. Now, I just stare wide-eyed and have a chonic I have no idea why I’m here mentality

…so I stopped the Effexor (cold turkey) but I’m still on the Wellbutrin.
Besides the nausea I’m just so irritable, nervous and almost aggressive. My memory is actually getting worse right now (can’t remember on Wednesday what I did on Monday…etc.) … withdraw side effects.
I really hope that those memory damages are reversible in the long run.
Some folks here posted that the memory damage is permanent, even after stopping Effexor. I can’t believe that. The brain is quite good in “re-mapping”… using all those spare cells we never actually use.
Does anybody here have any evidence that the memory loss gets better after a while???
Any feedback would be appreciated. THANKS.

I have poor and find it hard to contrate.forgeting things i should know like how to add [sums] or how to spell and tasks around the house. one point I think i had some kind of black out or hallucinating where i did something even that i was conscious but remeber till later on [DAYTIME!]. my brother came to viste and he said that personality has change. help!im scared, worryed about this but might not be anything but im sure somethings not right?

I’m relieved to see that there are so many others losing their memory that are on Effexor as well. I thought it was just me! My dosage isn’t even considered high, but it definately is having bad side effects with my memory. I forget constantly where I placed things only minutes later, and lose my train of thought constantly

I googled “effexor makes me stupid” and ended up here. What a relief to find this discussion! I take effexor for fibromyalgia pain relief. And, while it does a wonderful job at that (as well as the obvious mood benefit), it does make me more tired and slow-witted. It’s gotten to the point where it’s affecting everything, home, nutrition control, and work. It does seem worse to me since I switched from XR to generic (faster uptake perhaps on the generic?) With the support of my MD I’ve been tapering off, but this is a long process (I do NOT recommend going cold turkey, having tried it once). I’m more determined now to really taper off, and to supplement and eventually replace the Effexor with Cymbalta or Wellbutrin if needed, but I’d prefer to be off of all of these. I feel like I need to be off of all of them to really know if it’s me (age or other related memory problems at 49) or the meds. I just don’t feel sharp or smart anymore… and it’s helpful to see that others have had similar experiences and side effects.

I’m 35 year old.I’ve been taking effexor xr for about 3 months (cant remember exactly) for chronic depression and Post traumatic stress disorder.I was originally taking Zoloft)Now I find that my memory is getting worse, it feels like there is a concrete block in my head.last few weeks I really don’t care about anything or anyone.I’ve stopped thinking about the traumatic events which caused my situation (which is good) but now I cant think or focus about anything.I lie in bed for hours staring at the ceiling trying to grasp a thought.(any thought)but there is nothing there or maybe nobody home anymore.I have given up on going to the Psychiatrist.I really can’t be bothered with anything! I’ve lost my job, I’ve resorted to selling myself (because I just don’t care about myself anymore!)and I need to look after my teenager and pay bills.I cant be bothered talking to anyone about it.I feel like I’m stuck in a big hole that if only I had some energy (like a normal person) and if I could string a thought together, maybe I could get out of it!The only big bonus that effexor has given me is that I now keep my house tidier?

I’ve been on Effexor XR for 4 years now and have had a lot of memory loss. I have difficulty focusing and can’t remember facts as well as I used to and my short term memory is awful. I got by in high school on my memory, and now I can’t remember the simplest things.

I have been having a hard time staying focused at home. I am taking math classes and having a hard time remember stuff that used to be very easy for me to remember.

I had been on effexor xr for 6 months. My mail order got messed up and I did not get it for about a week and a half. In the mean time I went thru the withdrawal. I always felt dizzy, ears always had a whishing sound in them like having a sea shell up to my ear. Speech slurred, unfocused, Unbalanced on my feet, fatigue, memory lost, just really out of it. I really thought I had had a stroke. I went to work feeling bad, found a place to lay my head on my 15 minutes breaks and hour lunch. I think I had gone through the worse of the withdrawal symptons so when the medicine arrived I decided not to take it anymore. I did not ever want to feel this way again. I am doing much better as far as my reason for taking effexor xr in the first place, except for being unfocused and memory loss. I have been off of it for 3 months now. Now this being unfocused and memory loss is another thing. I have been doing a particular job for 2 years same procedures every day. Now all of a sudden I am having a hard time remembering how to go about doing the job. And work that I have done earlier upon my taking effexor xr are now coming back to hunt me. I was not aware that I was making all these mistakes, It is so embarrasing. To make common sense decisions is a challange. Just this past week I missed a step in processing a job that will cost the company money. I love my job and I take pride in my work. So to come up yet again with all these mistakes is driving me crazy (as well as my boss). I thought a was losing my mind until I went on line and type in unfocused and memory loss and low and behold this site popped up. I feel so much better knowing there is a reason for my shortcomings because I will have to try and explain this to my boss after the holidays, as well as, I will have to find a solution to this problem. Good luck and good health to you all.

Has anyone contacted Wyeth or gone beyond their literature to research the supposed correlation between Effexor XR and memory function? One post indicates a person sure to know chemical interactions on memory and yet indicates nothing about research.

Please post any findings or sources other than the one book listed in these posts.

Thank you.

My husband has been taking Effexor for about 5 years. He just turned 50 and over the last year or so has been having terrible memory loss. Mostly short term problems. I’m so thankful I found this site, except what does a person with bad depression switch to? He cannot go off of his meds as his depression causes severe mood swings, suicidal thoughts, manic episodes, etc.

I’m a 51 yr old male and have been on Effexor for about 6 yrs. My memory continues to deteriorate. I saw Suzanne Somers on Larry King last week who mentioned memory loss as a side effect of Effexor and Lipitor. I’m on both. I’ve experienced both short term and long term ML. I take Efxr every other day BC I find that dosage allows me to continue an active sex life with my wife. I’ve always had a bad memory but over the past few years I’ve noticed a progression that really concerns me. I’m trying to learn a new lanquage and am finding it next to impossible to remember words I learned just a few minutes past. I’m glad I’m seeing I’m not the only one and will discuss this with my doctor.

I’ve been on old school Desipramine for 15 years. Got weird side effects from 6-8 new age SSRI’s (close)that I tried. And literally everyone who’s been on antidepressants over a duration of time all seem to have similar complaints over short term memory. Wellbutrin especially seems to have many nasty side effects….in my case, got the equivalent to whiplash in 5 days. Quit and symtoms cleared up within 48 hours.
-Gerry

I was on Effexor for over 8 years and when i had to quit taking it when I got pregnant with my son the withdrawl was awful…. and then when my levels would drop abit.. I was going thru withdrawl all over again… In the last 2 years the memory forgetfulness has gotten worse…. I have recently been switched to celexa… But I am scared the memory is gone for good… I am gonna talk to my dr next appointment and see what she says. Its nice to see others have gone thru what I have.People told me I was faking it. I have forgotten things that are so simple…. It drives me insane!!

I just started on effexor 2 weeks ago and have noticed memory problems already…I am going to stop taking it immediately….seems like it should be listed as a major side effect.

I’ve been on Effexor XR 150mg/day for 5 years now and have finally reached the point where I am willing to experience the horrible side effects to regain my memory and ability to concentrate. I have concurrently taken Lamictal 200mg/day the the same length of time and thought maybe the memory loss was due to that. However, after reading these entries and being told by my psychiatrist that he has never had complaints of this from taking Lamictal I am 98% sure it is the Effexor XR. I am in my early thirties and don’t feel confident enough to apply for jobs which will further my career along because of the difficulty I have now. If this is what it can do to your mind, I don’t want to be on it any longer than necessary. My depression is now in check and might be able to do well on something else. Thanks for all the comments – it helps!

Wow! It would stand to reason that a doctor could take one look at the 184 comments on this subject and see that Effexor XR definitely impairs a person’s memory! I asked my Psychiatrist and my Family Doctor about the possible risks/side effects before taking this medicine and was assured that it was a safe antidepressant. WRONG!

I took Effexor XR for about one year and now can no longer handle finances, keeping appointments, nor working at the professional level(I have a master’s degree)job that I used to enjoy. Instead, I am a basketcase who can’t handle a checkbook and has to have a family member with me just to go on trips to the grocery store. I’ve applied for disability and most likely will get it, my psychiatrist believes, primarily based on the memory impairment…this psychiatrist, by the way, still denies that there could be any link between Effexor XR and memory loss; This doctor believes that the memory loss was due to the extreme level of stress, anxiety and depression that I exerienced(the most severe of these occurring during the horrible withdrawal from Effexor XR the last two months.) This drug should be banned-it has destroyed too many lives.

Oh my god! I am so glad that I am not the only one experiencing this. I have truly been starting to get scared there was more going on with me. I am definitely going to consult my doctor about this and possibly stop taking it.

This is incredible. I thought I was crazy and getting old, but I’m only 26 and had always had a good memory before I started taking Effexor. I feel like I lose track of time, forget people’s names, faces, what I was about to do ten minutes ago and whether I did something before or not. Oh and the brain zaps, my goodness I had them and wouldn’t have known what to call them but just hearing about them makes me think, yes that’s exactly what I’ve experienced, like a buzzing in your brain. Sigh* I had not heard yet that it was really difficult getting off the medication. Now I’m kind of scared to even think about it.

Add me to the list. I am 47 and have been on Effoxor for 3 years. I take the original 100 mg form. No question the memory is different. But in all honesty the drug has changed my life. Perhaps the short circuiting of some memory is one of the ways it works. One way to combat generalized anxiety disorder is to understand the thoughts, or mental processes, that trigger anxiety. No making excuses, just trying to help. God bless.

I was on Effexor for 5 months and the memory problems were almost immediate. I had trouble remembering words. It really became noticeable when I went back to university. My GPA dropped from A- to B. I couldn’t make “connections” in my brain and when I went to get information it was like the “file folder” was empty.

A friend suggested that I check side effects of EffexorXR, which I’ve been taking for depression for a few years. I’m 67 and thought the memory thing could be my age. Started at 75 mg and moved up to 225 mg within the last couple of years. When I didn’t see anything about memory listed by the manufacturer I searched further and came across this site. On the one hand, less than 200 comments in a few years doesn’t really seem significant. On the other, I’m glad to know that I’m not totally alone in what I’ve been experiencing. I’ll wean myself off this either alone or with my doctor’s advice. I’m very grateful to the others who took the time to write about their experiences.

Wow! This has been like reading my biography. Been on effexor xr 150 for about 5 yrs. I’m 63 and was sure that I was suffering from alzeimers. I get lost going to familiar places, call the kids and grandkids by the wrong names, forget appts, get 3/4 through reading a book before I realize that I’ve already read it. It was so frustrating. I used to be a math wizard. I worked for years as an accountant. Now I can’t even help my youngest with her algebra and geometry. If I forget to take a dose for a day or two, I have outrageous dreams/nightmares. I’ve also been suffering from extreme hot flashies and non-stop persperation.. It’s standing joke among my friends that no matter the temperature, I wear sleeveless tops and open-toed shoes. I have talked to my doctor several times about my symptoms and he NEVER suggested that effexor might be causing them. I WILL be talking to him again. Thanks everyone!

Wow, is right! I just called my dr. after taking Effexor for 3 years. My coworkers, my husband and myself have all noticed my memory loss. I just figured with chemo and medications and age (45) that this was just part of life. I’m on Effexor to balance the side effects of Tamoxifin, that I need to take for the 5 yrs after cancer. I am going to switch for sure after reading these other entries!

I took Effexor for several months in 2004. I quit it because it didn’t seem to help my depression and all my friends said I seemed weird on it. I was not aware of my memory loss until several years later when I was reviewing an online journal I kept and I saw an entry about a minor automobile accident I was in that I had absolutely no collection of. Looking back on the time, I remembered a friend of mine said I did something that I had no memory of, and it made me think I may have lost that memory as well. Today I was reviewing my Netflix history from that time frame and about 1/3 of the movies I rented and rated I have absolutely no recollection of. I have had no memory problems at all since quitting the Effexor XR.

I just searched Effexor and memory. I’ve found that Effexor makes me very sleepy and if I go without sleep (or even have less than maximal sleep) my memory is shot. Others have noticed this about me, so it’s not just me. I’ve only been on the drug for 6 months, up to full dose for 4, so the change is marked.

38yrs old. European Male. 2 kids – one is 5yrs old the other is 8 months.
Been on Effexor XR for 8 years. Paxil before that. Brother passed away before that.

I have noticed memory problems, but its been around stressful times in life. After my oldest one was under a year to maybe 3 years old, it was a stressful time. My brain was mush, and felt it was to much spongebob! Once he became a bit more independent, i became stronger, better w/ my memory. Even picked up a habit of drinking coffee in the mornings and found it improved my concentration. Got interested in everything again.
Well, we have an 8 month old now, and i notice i’m in the same boat as before. What has changed, lack of sleep. My wife isn’t on any drugs and her mind has also ‘went’. And she was a gifted student.
I do however, wish DR’s would put people on an excercise program and/or fish oils – herbs before pushing the hard drugs. I would love to get off this drug becasue i hate feeling dependant on it. But the withdrawl is hard to deal with and my family is dependent on me working full-time for a roof over our head and food on the table. So i can’t miss any work. I think a month off work would be ideal to get me off the drug.

Also, i would like to see everyone posting, their background : on race (nationality), male or female and age, and how stressful there days are form a scale of 1 (not stress) to 10 (very stressful) And maybe where you are from. I think winters are tough for many.
I’m in the northeast.
I’ve took Cipro once and found i was allergic to it. It screwed me up by adding anxiety and noticed i clinched my jaw, so are many of you on other drugs, no matter how short a time? I was looking up Fish oil and Effexor to see if that combination was ok. Thats what brought me here.
Good Luck everyone.
Calm the mind, and you’ll notice your body will follow.
Mark

Absolutely I have experienced short term memory loss. I have been on Effexor for less than a year and I have been worried that I have early Alzheimers. Has anyone gone off the medication and experienced that your memory got better?

after 4 months of being on EVIL EFFEXOR

after 4 months of effexor, i had to get off my vision would vibrate. that was june 08 now i don’t feel anything. the anxiety and depression are gone. I am sure i have brain damage from this stuff. Have confusion, lots of trouble communicating, can’t drive. thought process is gone. I CAN DEFINITELY SAY THIS HAS GIVEN ME BRAIN DAMAGE….I don’t know what to do anymore!!!!!!!!

I’ve been taking XR at increasing doses for a year and a half. I experience the memory, concentration, word-finding problems, and etc. However, I experienced the same prior to finally seeking help for my depression. I notice that such problems are most noticable during stressful times. When I am relaxed, busy, and happy, I notice little if any problems. I believe the problems are due to the depression, and it’s lasting brain effects. Regardless of the cause, I’d rather be happy with some memory issues than endure the pain and problems of chronic and espisodic major depression!!! Focus on what you CAN do! And live in the MOMENT!!

I have been on Effexor for maybe a month and a half. My memory has gotten really bad over the last week or so. I want to come off the medication before it has any long term effects.

I lost my second job due to severe memory loss. As many of the comments above, I can’t finish sentences, forget even which side of the street to drive on, which floor I live on, my kids’ names, etc. It’s made a MESS of my life!!! I changed to Pristiq with no help at all. The depression, however, is so bad without something. I think maybe I’ll try Cymbalta? Any suggestions for those who have gone off Effexor to something else that works?

I also have been wondering about this for some time. I am drawing blanks on tests in school. I also have been more forgetful than usual. This morning my doctor took me off to see if there is a connection for me. He told me that with many of the Anti-depresent’s memory problems affect a % of patients. Drug therapy is his practice at a large HMO. I had the same problems with Lexapro but it seems to be worse with Effexor

I started on effexor XR in dec ‘06, my memory hasn’t been the same since…I have also had attention problems, since stopping the drug in oct 07 these symptoms has lessened in severity, but my mind isn’t as sharp as it used to be…I was also wondering whether or not anyone has experienced slight shaking of the hands…my right hand has been affected to the point where it is noticable by others, I am only 20 years old and cannot find any other explination for this.

The withdraws will kill you but I did it convulzing and seizures right in the hospital.

I’m 23, and have been on and off antidepressants and for the past 8 years. I moved north for college and was experiencing increased seasonal depression and anxiety, and ended up smoking pot daily in combo with antidepressants and anti-anxiety meds. I became more and more dysfunctional until I dropped out of school and checked into a hospital. No school meant no health insurance, so I painfully weaned off of everything and have been fairly miserable for the past year. My mom was just thinking of starting an antidepressant, so we were going through my experiences and I TOTALLY FORGOT I’D EVER BEEN ON EFFEXOR. The next day she came home with her Rx for Effexor and I realized. I can FINALLY read a whole book, (hadn’t been able to for YEARS,) but college was a waste, as I retained nothing. I believe my memory is intact, but the retrieval system is still altered. I still rerent and rewatch movies that seem “familiar”. I KNEW it wasn’t the pot, but now what?

P.S. Fish oil seems to boost my mood a bit, without any side-effects

I should add, I had only been a light smoker, but stopped smoking pot 4 or 5 months ago, without any change in memory since.

I have been taking various dosages of Effexor SR for many years combined with Depakote as a mood stabilizer for bipolar symptoms. I suspect memory loss and some of the other symptoms described above are not unique to effexor. My husband and I both have shaky hand when using depakote. As his primary complaint is depression, he switched medication and he no longer has that symptom.
We both have memory issues, but take different meds. We are professionals who work together which means a dual to triple calendaring system to make sure no one and no task gets lost. Someone suggested that taking these meds is making a “deal with the devil”. I view it more as a symptom trade-off. I do miss the capacity for hyper-concentration and sharpness of functioning, however.

Hello. I´m bipolar and I´ve had major depression at least 3 times and mild depression 2 or 3 times(thanks to early diagnoses)since I was 16 – I´m 27 now. I´m on therapy for at least 9 years and my psychiatrist is very very competent. I took effexor on 3 different ocasions and it has worked greatly for me. Of course I have experienced some side effects, but it always paid off.
Depression have many different symptoms, not only the sadness and the non-stop crying. Apathy, anxiety, problems with affection, and mostly MEMORY LOSS and cognitive problems are some of those symptoms.
When a person gets depressed he(she) looses a great number of brain cells, The brain gets fisically sick. That happens
also with mania. Each episode – manic or depressed – leaves a scar on the person´s brain. THAT causes memory loss. Your doctors are right. And it takes a while after the depression or mania are treated for the memory to come back – but it´s not quite the same as before – because of lost the brain cells. That´s why is so important to treat it before it gets too serious. It seems to me that you are too focused in blaming something else (in this case your medication) to try to avoid looking into yourselves and the issues that may be harming you. Therapy + medication is the best way out.

P.S.: I never had to take efexor for more than 1 year to be ok.

And my memory is fine and I´m doing great: I´m on my way to be a vet.

The SSNRIs (Effexor and Cymbalta) boost the effects of serotonin and norepinephrine. http://en.wikipedia.org/wiki/Serotonin-norepinephrine_reuptake_inhibitor is the wiki page with fairly accurate information that is quite helpful.

Studies have shown that intense emotions help with short and long-term memory. If you are taking an SSRI or an SSNRI, you will likely not benefit from those intense emotions. It’s a trade off, for sure.

I have a very good memory from when I was very young (due to intense emotions), but I find that I have some troubles now (possibly because of medications, but possibly because I’m loosing my…gulp…mental functions). Taking drugs to modify emotions is not as much of a science as we’d like to believe and it’s definitely not without risks.

I have been taking Effexor XR 225mg. for 14 yrs. My memory problems began 4 to 5 years after starting. Stress was given as an answer to my concern over memory proplems…now I’m told it is age related. I’m scared and need to get off this drug. I hope that I can get my mind back, because I don’t know how I can support myself with such diminished capasity.

I am 32 been taking effexor for about 4 years and my memory is so bad. It has been getting very bad and my boss and co-workers poke fun that I am a scatter brain. I began taking the drug after problems with PTSD after being in Iraq. I am a mechanic and it is very hard for me to do my job because memory is key when pulling apart an engine. It is short term loss. This is very frustrating and I am going to try and get off this stuff. I thought I was getting dementia. I have never been absent minded and managed a large number of troops in and out of combat. My memory and mind have always been clear. I use to work on some of the most advanced weapon systems in the world. Now I set a wrench down and have no idea where I put it 10 seconds later.

I’m 37 years old. I made this deal with the devil/symptom trade off. I, too, am a college graduate from a Tier 1 university.

I’m Bipolar 1, and it isn’t just the manic and depression episodes that killed my memory. It’s the 150 mg of Effexor XR, 150 mg of Lamictal, and 100 mg of Wellbutrin I’ve taken for the past SIX years. It’s the short term memory loss that is the worst. Effexor XR is the worst of them. If I take it 4 hours later than my regular schedule, I’m pretty screwed mentally for the day. Forget it altogether? I’ll throw up. This is a heavy duty drug. I went on it willingly. This is the only cocktail that has helped the bipolar.

And I’m going to stay on it. I don’t have severe manic or depressive episodes anymore. This is my trade off. Can’t do the fish oils because I’m allergic. I will try the magnesium (thank you). Maybe it will help the memory loss. Slow it down, something.

Oh and I’m doing a durable power of attorney for health care and finances just in case I completely lose it. =)

Good luck to everyone!!

*Forgot*(heh) to add my symptoms:

1. Leaving my keys in the door (did this just 10 minutes ago)
2. Having a coworker mentioning a name and forgetting it 30 seconds later (while trying to write it down)
3. Going to another room and forgetting the reason why I had to go in the first place.
4. Putting something in a place where it’s NOT supposed to be, which makes me search for it later.
5. Forgetting people after I’ve met them a week earlier.
6. Forgetting I took my medication 5 minutes after I take them.
7. My favorite: I had my keys with me, and I was on the couch thinking of a special place to put them so I always know where they are. I proceeded to forget about the keys altogether and left them on the couch.

Man, this list can go on ad infinitum.

Microsoft Outlook reminders are a GODSEND, and I highly recommend its use.

Yes, just like Cheryl experiences. I am on 450mg. Inability to conduct my chosen profession adequately. In Australia, suing my psychiatrist for inappropriate treatment for Bipolar when I was not bipolar. Now just on Effexor and valium and the mem loss has commenced since I was off the bipolar anti psychotics….plus confusion. Terrible….

I too experienced memory loss on effexor xr. I would be in the middle of a sentence speaking with my family members and forget what I was about to say or even what we were talking about. I told my doctors also and they never even acknowledged my concerns only to say, “that’s wierd!” I would be on the isle of the supermarket and forget what I turned down the isle for and so on. I am now on Prestiq and not sure if it is working the way its supposed to. I will research and visit doctors until i beat this thing. I really hope and pray you get what you need from your antidepressants, but I just wanted you to know that you are definately not alone.

I have also had memory loss and I am only 25. Me and my friend both have tons of memory loss and we both took it. She was on 75 three times a day and I was on 75mg once a day. I cannot remember anything. Not very helpful for my job as well.

This is interesting, and I’m glad to see I’m not alone. I’m 30 now, and was on Effexor XR for about six months almost two years ago. In addition to not helping my moods whatsoever, it seems I have developed an inability to consistently remember day to day things like dates, appointments, some events and conversations and some fairly simple work-related tasks.

I was suspicious that it was the drug, but have never taken the time to check into it until now, as the problem still persists.

I also found that this drug changed the way I processed and responded to alcohol. I began to become very drunk, quite suddenly, after only a few drinks, at which point I could easily angered or otherwise negatively emotional.

Thanks for your posts.

Has anyone experienced this with OTHER MEDICATIONS as well? My memory problems have been on-going even when I was no longer on Effexor but still on other antidpressant(s). Or does it just not get better?

I was on effexor for 4 months (over 2 years ago). The two major side effects I noticed were short term memory & verbal communication breakdown (including vocabulary loss). How many people have to experience this before its listed as a side effect?

I took Effexor roughly ten years ago for a short period of time after my doctor prescribed it to help with fibromyalgia symptoms. It did nothing for those symptoms but immediately I experienced problems with my equilibrium, weight gain, and most importantly MEMORY LOSS! I told my doctor about those symptoms and he suggested I increase my dosage and give it some time. After a few months of these adverse symptoms just getting worse I decided to slowly go off of it myself (I switched doctors too). To this day my memory is horrible. It is so frustrating. I feel like I am on the onset of Alzheimers and I’m only 38. Does anyone know of anything that can be done to reverse the memory loss?

Same here! I found that if I don’t make a list, I’ll forget to complete a task. I was hoping to find info on moving from 150 to 300 mg but I found this on memory and wanted to chime in. Sometimes I can’t remember if I took my pill, like today so I am just going to take hope for the best and take another one. My only real concern is that I really don’t care much about the things that used to get me fired up. That internal fire that I had that motivated me to clean when I was angry to rush because I was running late is GONE! I suppose if I did go to 300 mg I may not care enough to go to work. Hope my husband doesn’t read this.

I googled for memory loss on effexor to see if anyone else is having the problem. I have been having memory losses, but i am not on effexor anymore, but maybe it is not memory loss too much but a struggle to remember. However, i used to teach and i could read a book and remember so much of it, now i struggle to remember what was on the previous page.
Has there been any study on this?

Thanks for everyone leaving these comments. I just was prescribed 37.5 dosage(s) of the medication yesterday by my family physician. I need my memory as it is the key to my successes in life. It sounds like this medication has serious sideaffects, that I do not want to take these risks I have seen posted here. None of this was mentioned by my physician but it sounds like you folks have connected the dots to this medication and memory loss. Whether this is characteric of the drug in general for everyone who knows. I am going to immediate discontinue use of the drug and find another remedy after reading these posts.

Thank of you for sharing this information.

I had taken one of the 37.5 pills before I found the article yesterday. Late into the evening I was doing a couple of things, and suddenly I found myself at the refrigerator with my hands against it looking up, asking myself what am I doing. I just got confused as to what two items I was doing, and I had to slowly stop and think what they were. I don’t recall when I have found myself like that just staring into space like what am I doing. I just do not think this could be attributed to one dose, but I found it interesting the way I found myself. My body is extremely sensitive to medications and I know this left me feeling different and a little spaced this evening. I found myself sweating and warm today very abnormal for me. Could one dose affect someone if your body is sensitive like this?

I took just one capsule this past week, and I went back to my Vitamin-B’s, Omega-3, and other supplements. I also tried the SEROTAIN that is available at specialized vitamin places, and I did notice it did help but it didnt get me all the way there. I asked my MD and he said there was very similar compounds but not of the dosage levels a prescription had in those pills. I experienced several memory struggles this week beyond my normal, but I have found myself feeling with more energy and mentality like something was disengaged that was taking the life out of me. I would find myself exhausted on the weekends and completely without any lack of motivation and energy but no way to snap out of it.

In the defense of Effexor XR, I feel like something has disengaged something like electrically in my brain like a short circuit that I could not get disengaged with other prescribed relaxants. I been like this for years but it was like a constant of the symptons of possible depression that I just could not kick. It just robbed me of my life at times, but I knew that if I excerised alot that I felt better. The problem is there were times I had no engergy or motivation or ability to go. It was like my electrical system in my brain was grounded at times and I would just want to sleep and withdraw from contact with the outside world.

I know the Efflexor XR changed something electrically in my brain enough to disengage something enough to re-engerize me and start to recover my motivation. I listened to the physican tell me to take all the medications etc., but I am wondering maybe I just needed something to break some bad electrical connections that I could not get disconnected in my brain.

Im curious if anyone else has had any experiences where they thought they may have had bad brain electrical like short circuits but have recovered through some other means by feeling there have been a disengagement of those negative impulses that held them back from feeling normal.

I am going to speak with my physican again but I think the discussions will be beyond his capability to answer, and I wonder if Wythe monitors this blog.

I am thinking I will hold onto my prescription and if I see a slight return of where I have been mentality with some state of depression, that I take another dose of Efflexor XR to breakup negative electrical impluses.

I am an extremely successful person in life, and I was even concerned about going to the doctor to discuss my condition and situation. Finally, I could not take it anymore and had to seek help of feeling lifeless.

I recently went over to a different health care with a primary physican that I have not seen. In dicussing with them in a telephone discussion, I was immediate given the impression, oh another “nutcase” is on the phone and what all the steps would be with psychological help and potential meds.

My long time general MD that I just have the greatest respect for, I decided to see him rather than the other healthcare plan.

My questions to him were how can they determine which medication or how can they measure your serotonin level and other levels to know what to prescribe. I wanted to know how scientific the process was if you needed to be medicated. I basically came away with the feeling its not really a measured situation other than your counselling sessions seem to determine what might be best depending on your issues, and it was like determining which drugs might be better suited for that problem.

At this point, I have determined to see my general MD again and get further advice if I see a progression back again if I take an Efflexor XR to see if I can reproduce the process of breaking the negative brain activity with the negative electrical impulses.

Again, I am wondering as crazy as this sounds do others find themself in similar type of situation(s) deploring to take medications if you do not have too just because a medical proffessional or a company tells you to take all your medication? Can there be those situations you just need to like reset your brain activity like rebooting your computer?

I’m on venlafaxine, I have trouble concentrating, I can’t even watch a movie, I’ve never experienced memory loss, but I also get restless legs, I need to move them for some reason, I told my psychaitrist and he told me that it’s not a side effect, but I didn’t have it before starting venlafaxine.

I started taking effexor XR in May after my husband was in as erious motorcycle accident and I went crazy threatening to kill 10 people for blowing their horns at me at a parking garage, since I no longer have that desire, but I have difficulty sleeping, and this past weekend I brought Charlie home for the day we got him out of the SUV into his wheelchair and the house, I started painting the guest bath and an hour later remembered I did not turn the truck off let alone pull it in the driveway but left it sitting in the street. I am very concerned here and think I will go back to my herbal hormonal replacement and risk Breast Cancer.

My forgetfulness has caused many problems in my personal life. My husband is sick of me forgetting and wants me to stop taken effexor. I need my medications for depression. My short term memory is shot and I lose track of so much.

HELP! I’m really worried now! I’m having all the same problems – severe memory problems, inability to learn new information and even basic processing. I am a child mental health practitioner and my job involves daily assessments of suicide risk, which is obviously a huge responsibility, and these cognitive problems are gonna lose me my career if something doesn’t change soon. I end up having panic attacks when I’m cornered and can’t remember crucial things. HOWEVER: The only reason I started taking effexor in the first place is because I had a break down at work which was triggered by panic due to memory loss and confusion! I was having all the same problems WITHOUT this drug, yet it’s got worse. So… what the hell is going on with me? I’m beginning to wonder if I wasn’t depressed in the first place, but suffering from acute and chronic anxiety due to prolonged stress in my life. An anxious mind will struggle to concentrate, have racing thoughts, and therefore be unable to pay attention and retain information! I have OCD aswell, which in itself, is an anxiety disorder. I insisted that I wasn’t depressed at the time, but the P.docs insisted that I was! My main concern now is whether the damage to my brain is permanent, whether or not the Effexor is making things worse, and whether I should try to come off them by using a benzo or something. I was prescribed Clobazam recently for panic and anxiety, so perhaps I could use that? I guess I need a new referral to a P.doc..
Has anybody here got any answers or suggestions?

I forgot to say that I too have always prided myself on excellent spelling and on being very articulate, however, both have been affected significantly and it’s maddening! I learn directions to somewhere, yet cannot retain them even when making the same journey over and over. I have no drive any more (I miss my mania!) and don’t want to socialise. Friends are very worried that I’m becoming reclusive and not caring about my appearance any more…Hmmm, don’t know what to make of all this!

I’m a fourth year PhD graduate student who has been off effexor for 2 years and continue to see declines in my memory and ability to learn new things. I was previously on Effexor for 2 years and noticed the memory loss shortly after beginning but figured it was related to depressive symptoms or significant life changes at the time. I am an Ivy League graduate and always prided myself on my intellect. Math came easy to me. The first time I noticed the memory loss was after a few months during a job interview in which I had to do a few easy math problems. I just blanked. But chalked it up to nerves. Two years later I began teaching SAT prep and noticed it would take me much longer to answer the simple math problems than the kids – after getting nearly a perfect score on my SAT I couldn’t do arithmetic. My memory loss for song lyrics has also been dramatic. My sister used to joke at how easily I could remember songs. That always came easy for me, after a single listen. I’m currently trying to begin singing again with a band and can’t learn lyrics. My friends think it’s hilarious, or that I’m not trying, but to me the deficit is far clearer than that. I just CAN’T learn it, even when I want to, even when I’ve listened 100 times, or even when the material (like schoolwork or job tasks) is important. I simply can’t remember. Something is very wrong here. Very very wrong.

Re: comment above – I agree, something is definately wrong. I was doing a Masters in Psychotherapy and had to abandon the course after 18mths due to cognitive problems. I could not, and still cannot work out problems. It’s as though there is a huge segment of my brain that is inaccessible to me. Like you, I put it all down to the depressive symtpoms, but now I’m not so sure at all. Your comment worries me even more, as you say that despite being off Effexor for 2 yrs, you continue to see a decline in cognitive functioning. I’m worried about how reversible these problems are… what can we do? I think I will talk to one of the psychiatrists that I work with and ask him to check online psychiatric journals for any news about this drug.

I took effexor off and on for 8 years. My max dosage was 450mg. Back in 2004 I weaned off of it as I felt it was no longer working. After the withdrawl symptoms subsided I began to experience confusion, reasoning and memory problems which, at the time, I attributed to exposure to construction adhesive during renovations in my house. I began taking it again soon thereafter though I never exceded 150mg again. I finally weaned off it again this past Feb./March because in addition to the fact that it was not helping me, I began having memory problems(not remembering whether I took a pill or not, etc.) and felt “the fog” that folks describe here becoming even more dense. I remember telling my sister I felt brain dead. Since about April or May, it is as though a portion of my brain has completely seized up. I cannot follow conversations, make connections/determine direct, let alone indirect, implications of an idea or action of slight complexity(I’m still okay with knowing when it’s okay to cross the street… for now) because I can’t remember enough to complete a chain of thought. Like one poster said it’s as though I have a brick in my skull and when presented with a problem not encountered on a daily basis, though still relatively simple(well within my former capabilities), I draw a blank as to how to solve it. I can only get my news from the paper because I cannot keep up with the pace of news anchors( super frightening ). It’s as though I’m listening to another language I’m in the process of learning and catching portions of a sentence that I then have to repeat back to myself in order to fully comprehend. I thus have to use periodicals so I can read and reread articles and backtrack to facts I’ve already forgotten.
I can see where people who write that memory and cognitive issues are symptoms of depression are coming from but Ive had episodes of depression in the past and NEVER had problems to this degree. Apathy and concentration issues: yes. Problems with basic math and very basic comprehension: no. Repeatedly forgetting what your saying mid sentence: no. I am now on Wellbutrin and it is not helping with any of these issues. I wish more folks from a few years back would  visit and update regarding their status. I’m so afraid this is permanent. This in and of itself is making me want to kill myself. If my job were any more complex, I would have been fired by now. If it gets any worse I undoubtedly will be.

I’ve been off 75 mg Effexor Xr for approx. 4 yrs now. I was noticing slight memory loss at first (I weaned myself off, due to a massive lay off at work & of course ended up losing the medical insurance…that was horrible)…Now in the last 2 yrs, the memory loss has incresed dramatically. It’s scarey. I’m suffering at work. My family doesn’t understand…and my boyfriend is frustrated with me all the time.It’s ruining my life!I’m only 40 and my memory makes me feel like I’m 80 or 90 at times!

I’ve been on Effexor for many, many years. From a low dose to the current dose of 75mg. There is no doubt in my mind that Effexor causes loss of memory, and difficulty concentrating. I asked my psychiatrist whether these symptoms are a direct result from the medication. Her response was yes. When I went to another doctor, she said no. Her comment was it is from depression and anxiety. Really??? Then why am I taking the Effexor??? I refuse to take a higher dose for fear I will become a complete zombie!
I think it would be very interesting to see if any papers have been published by reputable doctors on this subject.

I have the same problem, it bothered me so much and was kind of scary so I quite taking them (slowly, as recommended). I quite fully about 2 weeks ago and I still have some memory issues but it is better so I know it was the meds. I never had this type of issue before the meds and I it was really bad sometimes. I think this needs to be looked into by someone because this could hurt people and maybe it is perminate after a long time on this medication, who knows. It got to thinking how scary it would be for an older person if this happened to them and their family thought they had demintia and put them on even more meds or worse. Good luck, I hope you can find something that helps but has fewer bad side effects. Prayer really helps but don’t be afraid to try additional some out there are maybe better for your particular system than this one.

In a way I’m happy to have found this site. But I’m also scared… To hear about so many who have problems similar to mine and to hear that the memory loss may be progressive and permanent. I am a GP who graduated at the top of my undergraduate class with no mark lower than an A in all four years. Then in medical school became severely depressed and was placed on Effexor 75 mg daily. It really helped my depressive symptoms but after 1 year I weaned myself off of it because I couldn’t concentrate and study while on it as I wasn’t making A’s any more. In the years since then, I have struggled with my short term memory and my recall for words and names. And it’s getting worse over time. It hit me yesterday that, because of the time frame, it could be a side effect from Effexor. Then I found this website with so many describing exactly what’s happening to me! Wow! And probably no cure. What disturbs me is that these medications get approved by federal agencies for use after proving effectives and low risk for side effects after trials of only 6 weeks duration!!!!!!! So our sorts of problems only come out with post marketing studies that may or may not be acknowledged by the medical community.

My best friend has been on effexor for 6 years. suring this time i have helped her through a uni degree and 4 hositalisations plus there have been many signifiacant things that have happened with family. She can not remember any major events or even imoortant conversations that took place.
She can not work as a nurse as she can not remember long term what she has learned and experienced. Emotions are what people use as triggers for memories but as Effexor turned her into the “Ice Queen” with no emotions. She can not remember or realte to events that she was apart of with any certainty as they are other peoples memeories as she doesn’t have any of her own.

Our relationship has been destroyed ad this drug meant the our relationship was a vague dream and she can not remember the dpression and suffering the entire family and friends went throught in helping her deal. She is now off Effexor and everyone that stood by her have been pushed aside as she is happy to move on with life while turning her back on everyone who supported her.

I HATE EFFEXOR and what it has done to her and how it has effected the lives of those around her.

After 12months of not taking Effexor she is happy (shich is great ) but she has decided that what people tell her what happened and she went theough doesn’t exisit as she can ot remember it.

I would reccommend Effexor for a maximum of 3 months but no longer as emotions and memeries are linked. Not emotional triggers can happen if the person involved isn’t feeling any emotions.!!!!
It has ruined more than just one life.

Withdrawal from Effexor was hell. I was weaned down to 37.5 from 300 over a one year period. I got suicidal every time my dose was lower than 75; my children called these my crazy pills because I would get crazy as hell if I was without my meds for over 24 hours. I had a photographic memory before use of this med. I now have very little recall of the four years I took Effexor, and my memory still is damaged. My final withdrawal required use of sedatives to control my hot flashes, restless legs, hysteria, tetany. My withdrawal lasted for many weeks. I can’t imagine any withdrawal from heroin, cocaine, crystal meth or any other drug being any worse. The prescription liner mentioned possible minor withdrawal symptoms. My physician stupidly said that my symptoms during withdrawal indicated that my body needed the med!!! Would he have said that about withdrawal from illegal substances or misuse of prescriptions for amphetamines or narcotics? How many lives have been damaged by this drug! When does this rate a major class action suit?

Sigh.

I have been off of Effexor for 5 years now. I was on it for a year and a half when I was 18-20ish. I can’t remember my exact dosage (ha!) but no more than 130ish.

I had horrible withdrawal symptoms. I was able to get off my taking apart the pills and going down 5 beads a day. I didn’t realize then that my memory was gone. I just felt out of place and uncomfortable in my family and life- like I was a stranger. I had forgotten all of that familiar family humor/interactions/inside jokes.

I went off in the summer after my first year of university. In year two of university (Art major), I found my desire to draw decreased dramatically. It became (and still is a chore).

In year three after university, the memory loss became very very evident. Couldn’t remember keys, homework. Still getting great grades, but couldn’t convert the information into my long-term memory. Therefore, I can’t remember MOST of what I learned in University. And now I am a teacher and feeling inadequate ever day.

Year three and year four of university were the worst for forgetting simple tasks. I cried for hours when I put a pizza into the over while still leaving the cardboard under it (it burnt). I nearly crippled my hand when I left a pyrex glass dish on an element that I forgot was on. When I noticed the dish smoking I carried it to the sink and dropped it into the water, and it exploded. Probably the most traumatic thing I have ever experienced. My engineer ex-boyfriend did not understand my memory problems and he ridiculed me for it.

Year five of university got slightly better in terms of forgetfulness. This went down. HOWEVER I still couldn’t remember how to CONVERT things I have learned into LONG0-term stuff. Got my uni degree feeling like I cheated the system- was able to maintain an A- average by cramming for every exam and essay the night before and spewing it all back out quickly so as not to forget!

Year one after university is very very slightly getting better. Still can’t remember names or quote Shakespeare like I used to, but oh well. I also notice that I don’t get stumped in conversations as easily, but my comments are no where near as intelligent as those of my peers. This causes great self-esteem issues.

So, does it get worse? Around year two of being off it. Does it get better? Very slightly. The extremely embarrassing things like word-recall have for me.

What hasn’t gotten better- lots. But now I am able to retrieve random memories at random times. And I am dreaming again if I take 20 mgs of zinc.

As for Masnesium, I take it daily at 125 mg- it certainly won’t hurt. Fish oil did not help me, but my body reserves of vitamin k are too low to take it, and it was causing skin bleeds.

My language has gotten very simplistic, but I think that this has plateaued out. I still mispronounce words, but what can you do.

SO there is hope. It will eventually go away. I still feel very disconnected from life, but am looking very forward to looking through the new family photo album my mom is preparing.

Perhaps this will get better in time too.

I have tried several differant approaches to dealing with sleep difficulties steming from anxiety. The various ‘potions’ all had side effects of one form or another and in hindsight the cure was often much worst than the desease.
My work demands the ability to think clearly and make informed decisions. This stated I took Effexor on 2 separate occasions (75mg XR). On the first occasion I found it to aid in my sleeping however with prolonged use I began to feel tired all the time and somewhat out of it.
I should have known better but after discussion with my doctor I ended up back on the drug after a 5 year absence. (This followed trials of Zoloft and Wellbutrin and I believe 1 other.) In any event I was assigned a rather large complex project of the type that should have been rather straight forward due to my familiarity with the equipment etc.
Initially the drug seemed to help however now that I have ceased taking it realize just how messed up I was. During the course of work I found myself doing and re-doing the same task and not being able to think clearly enough to drive anything through to completion.This affected my ability to make decisions at work and at home. In addition I seemed to forget what I was doing if at all interrupted and also found that I had to look up basic calculations which were generally second nature.
The end result is that I now realize that I totally screwed up a major installation. I was ‘let go’ as part of a mass layoff and have basically been black balled within an industry I worked in for 20 years .Other than being unemployed and feeling terrible for what transpired I am drug free and although not sleeping the best can at least think and reason better.
The personalities I was working with throughout the project were interesting and did not help matters. This stated, had I been on my game I could have easily given clear direction and ensured a sucessful outcome.
Upon my departure I decided it was time to try going without the medication. This led to a weaning off which was to say the least also interesting.I cut the dose from 75 to 37 and then extended the period between doses over a 4 wk period. At the end of this I experienced dizziness, what I believe is reffered to as brain zaps and intermittent upset stomach. This lasted for a further 2-3 months. This little pill has an huge impact on your body. Take care when getting off of it!
In closing, the drugs are probably great for a lot of folks however as I found the person taking the pill often times does not fully realize the impact it is having. If I had it to go through all over again I would strongly recommend maintaining a journal to document how the drug is affecting you.
In addition please take care if you are working in a position of authority or one which requires an attention span of some length.

Why is there not a class action suit brought against the manufacture of the medication? I saw the petition on the first page of comments but wonder if there is more to be done…..
I too took this pill and it really isnt worth it

Get off that shit medication!
I wet off of it cold turkey. suffered for 3-4 days but i am ok now.
Doctors know shit about metabolism, brain neurochemistry and micronutrients. i was depressed/bipolar and found out it was caused by a inborn error of metabolism causing me not to absorb vitamin b12 properly. The lack of this vit can fuck you up really bad. I was ok 24hours after i started taking the vitamines and minerals my doctor told me.
Go to a doctor you trust and do the blood test for vitamines a to z, Mg, Na, K, Cr… Psychiatrists know nothing about medicine. Take care.
P.S.: I was wrong about effexos not fucking your brains up. very wrong. Stop taking it. I think it is like anyother drug, sice sometimes it gave me this feeling of pleasure in my frontal lobe, like Xanax.

Get off that sh*t medication!
I wet off of it cold turkey. suffered for 3-4 days but i am ok now.
Doctors know sh*t about metabolism, brain neurochemistry and micronutrients. i was depressed/bipolar and found out it was caused by a inborn error of metabolism causing me not to absorb vitamin b12 properly. The lack of this vit can f*ck you up really bad. I was ok 24hours after i started taking the vitamines and minerals my doctor told me to.
Go to a doctor you trust and do the blood test for vitamines a to z, Mg, Na, K, Cr… Psychiatrists know nothing about medicine. Take care.
P.S.: I was wrong about effexos not fuc***g your brains up. very wrong. Stop taking it. I think it is like anyother drug, sice sometimes it gave me this feeling of pleasure in my frontal lobe, like Xanax.

I’ve been taking Zoloft for 10 years and recently switched to Effexor. It’s only been one week and I feel the same. My doctor was hesitant to increase my Zoloft (200 mg/daily) and suggested I switch. I lost my job six months ago and I am under a tremendous amount of stress.

I am reading all these comments about brain zaps and forgetfulness and it’s making me nervous. Zoloft always worked well for me, except that I gained a lot of weight while taking it. It could be due to the fact that I haven’t exercised in a while and just lazy sitting a round looking for jobs all day. I have to say, I don’t feel as hungry on Effexor as Zoloft. I don’t know if it’s just because I am anxious or not but I just found out I have high cholesetrol on top of everything. Still waiting on the breakdown of numbers but the total is 275- not good. Could it be because of Zoloft? Has this happened to anyone else?

Please let me know. Now I am freaking out that I will have a heart attack. By no means am I obese, just gained weight over the past two years and could easily lose 20-25 lbs.

I am scared I am going to lose my job – I have made so many little (not TOO bad, yet!) mistakes over the last few weeks -or since starting Effexor, and I am so unproductive. I just don’t care and everything feels like too much effort. I can’t concentrate and it feels like I can’t learn anything. When I try to learn I just get a frustrated headache and give up. I feel like I forget everything- I feel like I am going crazy…. but this may have started just before taking the Effexor – I can’t remember, exactly. Maybe this is just symptoms from my anxiety, not Effexor…. Maybe I should resign…. I want to cry

I’ve been taking Effexor XR for over a year, and I’ve noticed some memory loss. I have to use stickys all the time at work. If my wife gives me a grocery list without writing it down, I begin forgotting the items after about the 3rd or 4th item.

Niacinamide…. I read that it helps memory problems with Alzheimers. I searched online and it helps with depression. Big doses at least 500 mg 4x day. I’m living with someone taking Effexor. His memory is lousy and was worse when he was on higher doses of medicine. Maybe some of you can try niacinamide and see if it helps and report back….