Medication and Alcohol Wellbutrin and Alcohol Don't Mix
From daisys4me, for About.com
Updated February 21, 2008
About.com Health's Disease and Condition content is reviewed by the Medical Review Board
I took Wellbutrin SR for several months. I only drink occasionally, but the day after I had a couple of drinks, I would become more depressed. It would take around 3 days to snap out of it. I believe the alcohol would negate the positive effects of the Wellbutrin. For me, a few hours of being happier while enjoying a drink or two wasn't worth the days of depression that followed. I don't drink at all anymore.
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