Definition: Tricyclic antidepressants are older antidepressants which inhibit reuptake of serotonin and norepinephrine. In addition, they interfere with the metabolism of other compounds in the central nervous system, the amines.
Tricyclic Antidepressant
By Nancy Schimelpfening, About.com Guide
Updated September 22, 2007
About.com Health's Disease and Condition content is reviewed by the Medical Review Board
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