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Unipolar Depression

By Nancy Schimelpfening, About.com

Updated: May 04, 2007

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Definition: Unipolar depression is another name for major depressive disorder. It is a mood disorder characterized by a depressed mood, a lack of interest in activities normally enjoyed, changes in weight and sleep, fatigue, feelings of worthlessness and guilt, difficulty concentrating and thoughts of death and suicide. If a person experiences the majority of these symptoms for longer than a two-week period they may be diagnosed with major depressive disorder.

The term unipolar depression is used to distinguish it from depression which occurs within the context of bipolar disorder, a disorder in which a person experiences alternating periods of depression and mania.

Also Known As: major depression, major depressive disorder
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