Definition: Unipolar depression is another name for major depressive disorder. It is a mood disorder characterized by a depressed mood, a lack of interest in activities normally enjoyed, changes in weight and sleep, fatigue, feelings of worthlessness and guilt, difficulty concentrating and thoughts of death and suicide. If a person experiences the majority of these symptoms for longer than a two-week period they may be diagnosed with major depressive disorder.
The term unipolar depression is used to distinguish it from depression which occurs within the context of bipolar disorder, a disorder in which a person experiences alternating periods of depression and mania.
Also Known As: major depression, major depressive disorder

